163505 Medications Oral Ru - UWMC Health On-Line

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Diabetes Care Center
Box 356176
1959 N.E. Pacific St. Seattle, WA 98195
206-598-4882
120069
© University of Washington Medical Center
Diabetes Care Center
Medications: Oral Agents
Russian
03/2000r
Patient Education
Diabetes Care Center
Medications: Oral
Agents
Drugs that treat type 2 diabetes
Type 2 diabetes is a
complex disease involving
not just the pancreas but
other organs in the body as
well. There are a number of
medications to treat this
form of diabetes. Your
doctor can help you find
which one is right for you.
Medication Options
Drug
Names
Drug Class
Site of
Action
How They Work
Glyburide
(Dibeta/
Micronase)
Glipizide
(Glucotrol)
Repaglinide
(Prandin)
Metformin
(Glucophage)
Insulin
Secretagogues
• Sulfonylureas
• Meglitinides
Pancreas
Makes the
pancreas release
more insulin
Hypoglycemia
Biguanides
Liver
Decreases the
amount of
glucose the liver
puts out
Acarbose
(Precose)
Miglitol
(Glyset)
Alpha Glucosidase
Inhibitors
Gut
Slows the
breakdown of
carbohydrates
Rosiglitazone
(Avandia)
Pioglitazone
(Actos)
Thiazolidinediones
(insulin
sensitizers)
Muscle
Improves the
ability of
muscle and
other cells to
use the available
insulin
Diarrhea/nausea/
vomiting/gas⎯
usually resolve
with continued
use
Diarrhea/nausea/
vomiting/gas –
can minimize if
start low dose
and increase
slowly
Weight gain,
edema, liver
damage
Type 2 diabetes is
characterized by insulin
resistance which is the
body's inability to use
insulin effectively, and a
relative insulin deficiency.
Individuals with Type 2
diabetes have varying
degrees of insulin
resistance and insulin
deficiency. The challenge
is to match the individual
with the correct medicine.
Possible Adverse
Effects
Hypoglycemia, or low blood glucose reactions, can occur with insulin
secretagogues. It is very important that you not skip meals if taking
one of these medicines. The other classes of oral diabetes medication
do not cause hypoglycemia by themselves. If they are used in
combination with insulin secretagogues, the chance of hypoglycemia
can increase.
Page 2
Diabetes Care Clinic
Medications: Oral Agents
Notes:
Questions?
Call 206-598-4882
Your questions are
important. Call your doctor
or health care provider if
you have questions or
concerns. The UWMC
Clinic staff is also available
to help at any time.
___________________
___________________
___________________
___________________
___________________
Diabetes Care Center
Box 356176
1959 NE Pacific St. Seattle, WA 98195
206-598-4882
© University of Washington Medical Center
03/2000