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;BHEH=BYFHJYlhfk483–485 M>D FHJKD:YN:JF:DHEH=BY <EBYGB?WDKLJ:DL:BAFY=DH=HDHJ:EE: LOBOPHYTUM PAUCIFLORUMG:LJHNHAHBLH< ENTAMOEBA HISTOLYTICA IN VITROBIN VIVO1 ]R=hrZe1<EZdrfb2 1 Hl^_e_gb_fbdjh[bheh]bbb2Hl^_e_gb_obfbbP_gljZevgh]hbgklblmlZ bkke_^h\Zgbye_dZjkl\EZddghmBg^by e-mail: vijailakshmi@rediff.com KlZlvyijbgylZdi_qZlb] MklZgh\e_ghqlhf_lZghevgu_wdkljZdlubafhjkdh]hdhjZeeZLobophytum pauciflorum\mkeh\byoin vitro hdZau\Zxl Zf_[hpb^gh_ ^_ckl\b_ gZ ljhnhahblh\ Entamoeba histolytica b \ kemqZ_\ bae_qb\Zxl Zf_[bZa ke_ihcdbrdbmdjukH[gZjm`_ggZyZdlb\ghklvoZjZdl_jgZ^eyn[mlZghevghcnjZdpbbbadhlhjhc[ueb\u^_e_guljbqbkluokh_^bg_gby Dexq_\u_keh\ZZf_[hpb^gh_^_ckl\b_Entamoeba histolyticaZf_[bZake_ihcdbrdbLobophytum pauciflorum. Activity of soft coral Lobophytum pauciflorum extract against Entamoeba histolytica in vitro and in vivo. S. Ghoshal1, V. Lakshmi2 (1Division of Microbiology and 2Division of Chemistry, Central Drug Research Institute, Lucknow-226001, India) Methanol extracts of the marine coral Lobophytum pauciflorum showed in vitro amoebicidal activity against trophozoites of Entamoeba histolytica and effected 85% cures of caecal amoebiasis in rats. The activity was localized in the n-butanol fraction, from which three pure compounds were isolated. (Biologiya Morya, Vladivostok, 2004, vol. 30, no. 6, pp. 483–485). 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LOBOPHYTUM PAUCIFLORUM Bkoh^ybaihemq_gguoj_amevlZlh\fh`ghkdZaZlvqlh L. pauciflorum h[eZ^Z_l agZqbl_evghc Zf_[hpb^ghc Zdlb\ghklvx \ hlghr_gbb E. histolytica Ih ^Zgguf ^jm]bo Z\lhjh\ qbklu_ kh_^bg_gby dhlhju_ [ueb Zdlb\gu \mkeh\byo in vitro hdZaZebkv kl_jheZfb g_ ijhy\ey\rbfb l_jZi_\lbq_kdhcZdlb\ghklbijbZf_[bZa_ke_ihcdbrdbmdjuk&HGLOORV HWDOFy]dbcdhjZeeL. pauciflorum^_ckl\bl_evghijb\e_dZ_l \gbfZgb_ mq_guo LZd W^jZ^Z k khZ\lhjZfb (GUDGD HW DO hibkZeb Zdlb\ghklv kh_^bg_gbc ihemq_gguo ba wlh]hhj]ZgbafZ\hlghr_gbbnblhiZlh]_gguo]jb[h\Cladosporium cucumerinum ]jZfiheh`bl_evguo [Zdl_jbc Bacillus subtilis b ^jh``_c Saccharomyces cerevisiae <hafh`gh fhjkdb_ hj]Zgbafu fh]ml kh^_j`Zlv g_dhlhju_ ki_pbnbq_kdb_ obfbq_kdb_ kh_^bg_gby dhlhju_ lhdkbqgu ^ey fbdjhhj]Zgbafh\bwnn_dlb\guijbe_q_gbbq_eh\_dZ :\lhju \ujZ`Zxl [eZ]h^Zjghklv ]hkih^Zf $3 6LQJK +50LVKUDb130LVKUDaZl_ogbq_kdmxih^^_j`dm KIBKHDEBL?J:LMJU Anjaneyulu V., Babu B.H $ QHZ WULK\GUR[\ VWHURO PHWK\OFKROHVWHQH UWULRO IURP D VRIW FRUDO RI Lobophytum species of the Indian Ocean // Indian J. 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