о патогенетической взаимосвязи нарушений реологических

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56
-
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.
2.
Y.pestis
-
.
3.
,
-
2.
,
. –
. 33-34.
3.
.
./
.
»; 1998. –
., «
,
.
,
. Y.pestis,
,
.
//
1994. - 8. – .21-24.
4.
, .
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,
76./
.
.
»; 1999.
./ .
. - .: «
– . 390-422.
5.
.
.
/
.
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.–
; 1992. – .19-22.
6.
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– . 9-20.
7.
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//
.
. – 2002. -
Y.pestis,
1./
.
,
3. – .3-23.
.
-
.
, 1990.
,
.
.–
,
.
,
.
. //
,
. – 2000. - 3, (3). – . 5-12.
8. Tapper, H. Modulation of hemostasis mechanisms in bacterial infections diseases / . Tapper, . Herwald // Blood. –
2000. – Vol. 96. - 7. - . 2329-2337.
ON PATHOGENETIC INTERRELATION OF BLOOD FLOW PROPERTIES
DISORDERS AND LEMIC INTOXICATION COARSE SERIOUSNESS
Afanasyeva G.A., Chesnokova N.P.
Saratov state medical university of Roszdrav
The disturbances of the blood viscosity at different shear rates in dynamics of plague intoxication were investigated. Experimental plague intoxication of different degrees of severity
was reached by parenteral administration to mice of a endotoxin in a dose equivalent to LD50
and LD25. Correlation between the degree of autointoxication severity and integrative indices
of rheological properties of the blood was established.
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