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инструкция МТ медэкспресс

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AHMvlTl4'{ECKl',lE ]',iAuArHOcrl4qEcKl4E
14HCTPyKql49
Ane
,"ry"orporr"rorpaQravecxoro BbteBieHhn
r Mycobacterium Tuberculosis (MT)
""rri"r,
qenuxoi xpoar
B CbtBopoTKe (nnaarrae)
no npxMeHeHnrc (Ha6opa peareHroB
14
(hrurrlyxoXporrl-anru-MT'Sxcnpecc)D
XAPAKTEPI4GTHKI'|
Onoct,tenbHas qyBcrBllTenbHocrb onpeAeneHufl 83,0%' orHocureflbHat cneqrQnvrocru - 98,9% no ornouLernp x 6arrepuonofhgecKuM MeToAaM uccfleAoBaHil9.
BpeunnpoeegenntaHan[3a-10r,'unyr.
I
Ha6op lzhar,ryroXpou-amrl-MT-Sxcnpecc pa3peueH K npou3BOACTBy, npoAaxe I nphMeHeHIto la reppuropnr PO '
unu 20
Kaxautl4 sa6op npeAsaaxa'{eH Afle npoBeAeHue
onpegeneutt Haflt4tlue aHT[ren r MT e csteoporxe (nnasn're) n
qenutofr rPoeu qefloBeKa.
HA3HAt{EH1,lE
MEPbI nPEgocroPoxHocTl4
Ha6op 14rrlrrlynoXpotu-atrr-MT-Sxcnpecc npeAHa3Ha'{eH Anr In
vitro ogtosrannoro 6utcrporo xalecrBeHHol'o Bbl9BneHh9 aHTuren lgG, lgM r,r lgA xnaccoa k Mycobacterium Tuberculosis (MT)
qenbHol4 KpoBil qefloBeKa MeroAoM
B cbrBoporKe (nnasrrle)
14MMyHOXpOMaTOf paQuqecK0ro a$an[34.
[
c
Pesynurar, nonyveuuti
lz1
u
r.l4cflon$osaHneM Haoopa
ruyroXpotrl-amu-MT-Sxcnpecc,
He
AonxeH paccMarphBarb-
KaK eAIHcrBeHtutr,l rpurepni a gnarlocrnxe ry6epKyne3a, a
pe3yflbraAonxer 6utrs uHTepnpeTilpoBaH B coBoKynHocrl4 c
cs
florerquanutulil
pt4cK
nphMeHeH[9
-
rnacc 2a.
Ha6op 14 urvrynoXpotrl-asru-MT-3xc+pece-Fpeft€$lar+eH ToFbro !ns in vitro AuarHocrl4Kt4.
Bce xorltnotestut Habopa g flcnorb3yeMblx KoHqeHTpaq[nx
sBnFlorcfl HeroKct4tlHbtMl4 CocraanRoque nonocKh hMMyHoxpoMarorpaQuqecxofi ue copepxar MhKo6afiepuh ry6epxyre3a tlfl[ 14x Ko[4noHeHTbl, Moryqile npheecrr r ul$uqupoeanno.
flpu pa6ore c ra6opotu cnegyer co6rrcgaru "flpaeuna ycrpotacrBa, rexHIKtt 6egonacHocru, npon3BoAcrBeHHo n ca+Vr apt4v"
[t
pexilMa il fltl'lHol4 il4r[eHbl np[
pa6ore s na6oparopunx (or4enelnnx, orgenax) caHhrapHognugerruottot'l4qecxrx yvpe4qeluta cilcreMbl Murncrepcraa
llpr,rxqr,tn Aeficreuq. Ha6op ocloean Ha np[Hqhne uMMyH0xpouarorpaQr,tvecKoro aHanh3a. 14cnstryeustt,t o6paseq ecacutBaeTcg BnuTblBapquM yqacTKoM tlMMyH0xp0MaTorpaQfiqe-
3ApaBooxpaHeHun CCCP" (M., 1981 r )
flpr,t pa6ore c ta6opolr cneAyer HaAeBarb oAHopa3oBble pe3r4HoBbre [nI nnacr[KoBble nepqarx[, rar xax o6paaqut xpoau
cxofi nonocxr, noMeqeHHoh B nflaHUer.
qenoBeKa cneAyer paccMaTpuBaTb KaK noTeHqnanbHo t4HQtl-
TaMI Apyftlx KnilHuqecKnx uccneAoBaHu14
XAPAKTEPilCTI4 KA 143[En
npoTl4BoSn[AeMuqecKoro
E4l'|lQllEoe qpq4!1 qqlga[flTb
narura uru Apyrue aos6yAnren[
14
KoHblofhpo-
B cnyvae Han[ehfl B o6paaqe anruren x [tl-T, nocne4nnePepeKoM6uHaHTHblMu MT-alrrrelaun,
an4pyror
BaHHbrMl4 c qacruqa[lu KoJ]norgHofo sonora, o6pasyn
c
oxpa-
rrQexqntl'
oSoPyAoBAHl4E
uexruti rounrerc. 3tor xounnexc ABrxerce no ueu6pane
c OpoHToM xr,rAKocl4 t4 Bcrynaer B peaKqln c
tstuu MT-atrnrexanau,
utrllao6unn3oBaHHbtMt4
pexou6nuaxr- '
ta
ueubpale,
o6pasyn nnxuro posoaoro-$noneroBofo qBera B HuxHe14'lacTh
recroeola sonrr (T -
recr;.
.
ceKyHAoMep
14
MATEPI4MbI:
[nu qacbl;
nepqarKh pe3[HoBble
[n[
nj]acrrKoBble.
AHMl43l4PyEMblE OEPA3qbl
qenoBeKa'
cblBoporKa (nnasua) KpoBl4
ocranbHbre KoMnoHeHTbr npoAonxaor ABr4farbce no MeM6pa- HereuonuaupoeaHHas
l-lenulan xpoau (eeloslar [n[ Kan[nnqpHae)' [o npoae4ere r o$pasyrcr po3oBo-QiloneroByn nhHno e aepxlefi
cblBoporKl4 t4uh
,aaroroi sbnur (C - xonrpons) He3aBilct4Mo or npilcyrcrBr4e Hh9 aHartn3a Bo3MoxHo xpaHeH[e oopasqoa
+2-8"C
48 '{acoa'
ne
6onee
re[lneparype
npfl
KpoBl'4
ntla3Mbl
Bu3yanbHo.
peaKqflu
vacru
oqeHilBanT
aHTuTen K MT. Pe3ynbTar
cocrae
.
.
.
.
xa6opa:
Tecr-nnaHuer
B
repuernvron ynaroaxe-1
peareHT Ans pa3BeAeH[n - 1
cKaprot4Karop-1 ulr.
cn[proBag canQerra - 2
uLr
QnaKoH.
ur
lonycraercn nocraBKa Ha6opa
.
B
l'1uttllynoXporrl-alru-MT-
cneAytoqet KoMnneffiaquh:
Tecr-nraHuer
B repMeruqHoi ynaxoere - 20
. nunerxa - 20 ur.
. peareHTAnt pa3BeAeH[n
. cxapnQurxaroP - 20 ur.
MeHAyercF. 3auopaxnaaure Llensxori xpoau He AonycKaercg.
l'lepe4 npo6egenraeM aHanu3a KoMnoHeHTbl xa6opa u uccnegyeuste o6pa3qbt cneAyer BblAepx[Barb flp14 KoMHarHol't
uxcrpyxqun-1 ur.
3xcnpecc
ilil:l','J.il3i;#'i;JlffiJ5:rl.:lH il:il'3:.i.13.
NPOBEAEHI,IE AHAJI143A
.nhnerKa-1ur.
.
npu reo6xo4ur'rocru 6onee AflurenbHoro xpanenr,r (4o 2-3
ur.
TeMneparype (+18-25"C) B TeqeHue 5-10 ut'tryr'
Bcxpurrs ynaxoexy nnaHUera, pa3pblBae ee BAonb npope3h'
[3Bne'{b nnaHUer u norloxl4Tb ero Ha qucryo cyxylo fopl430HTanbHyro n0BepxHocTb.
- 1 QnaKoH.
Cureoporra
.
hrI
nna3Ma:
Bnecru c noMolllblo nunerKu
B
oKotllxo S (o6paseq)
nflaHUera 2 xannr,r (-80 MKn) cblBoporKh (nnaauut).
. 9epes 10 M[Hyr Bl43yanbHo oqeHnrb pe3ynbrar.
Onru6oqxsri pe3ynbtar. Orcyrcrene
{enuxan xposu.
.
ueTa rlH1414 po3oBo-Q[oneToBoro
Brecru c noMorlblo nrnerKu B oKotuKo S (o6paseq)
nnaruera 2 xannu (-80 raxn) qenuroi xpoeu.
. Kor4a o6paseq enrraerce, go6aaurs 1 xannn (-40
urn) pearerra gne pa3BeAeHne.
.
C (xonrpons) cBuAerenbcrByer o6 ouu6xe recrupoBaHxe
Cnegyer npoeecrn noBTopHoe onpeAeneHle c ucnoflb3oBaHHeM Apyror0 nnaHUeTa.
ycnoB[fl
KpoB14 HenocpeAcrBeHHo
13 nanbua.
. fun
nonyvenur xanunnrpxoi xpoau o6pa6orars
naneq gesur$r,rqupynqeti canSerxoi
I
npoKonorb efo
cKapuQuKaropoM
.
flosnqnorupoaaru nporonorutfi cxapn$nxaropotrl
S (o6paseq) nnaHUera
ynacrb
B oKoluKo Korga xpoau
KpoBr4
anuraercn,4o6aanru 1 xannn (-80 urn) pealeHTa Me
pa3BeAeHug.
.
XPAHEHl4fl
14
3KCnIyATAUl4l4
Ha6op lrlrr,uaynoXpot'l-arrn-MT-Srcnpecc AonxeH xpaHurbct
B ynaKoBKe npeAnpugTxfl-n3roToBl,lTeng npI reMneparype +228'C e reqeHue Bcelo cpoKa foAHocrt4. 3auopaxuaatne ta6opa re gonycxaercn.
Cpox rogrocru - 24 uecnqa.
naneqraK, qro6st rannn KpoBh HaxoAnnacb HaA oKotllKoM
. fiars 2-l,r KannsM
TecroBoi 3oHe nnaH-
xr,r
9epes 10 MlHyr Bn3yanbHo oqeHurb pesynbrar.
llcnonsoogaxlre Kanunnf, pHoi
B
qBeTa Ha ypoBHe MapKlp0B-
'gr
l4sene,reHxurH r43 yflaKoBKt4 nnaHuJer pexoMeHAyercs
3oBarb
B
TeqeH[e
'1
vaca nocne ecrpbtrl4s
[cnonb-
ynaKoBKt4.
lnr
nonyvernr HaAexHbrx pe3ynbraroB xeo6xo4ut'lo crporoe
co6nrcgerre uHcrpyKqun no npuuetenrrc ta6opa.
ulepes 10 MuHyr B[3yanbHo oqeHurb pe3ynbrar.
He cnegyer [HTepnperxpoBarb pe3ynbrar no3AHee, qeu
ueper 30 unryr.
KOHTponb
TECT
-
-
- oKolllKo
gnn o6paoqa
flonoxnenuruti
pe3ynbrar
Orplqarenuxuttr.
Otur6oqrui
pe3ynbrar
pe3ynbrar
flo eonpocan, KacatoquMcfl (a\lecrBa xa6opa pearelroa
14ur,,rynoXpou-aru4/T-3xcnpecc cfleAyer o6paqarscn
l,tHTEPnPETAql4t PE3yITbTATOB
PerrurparyrperptraroB
Bt43yanbHzln.
llonoxlrrenuxuri pe3ynbrar. ButqaneHre g tecrosotl gote
nraHuJera Ha ypoBHe MapKr4poBoK T (recr) I C (xotlrponu)
gayx nrtrt,tr,t posoao-$uoneroeofo qBera cBuAerenbcrByeT o
nonoxrTeflbHoM pe3ynbraTe aHan[3a, T.e. yKa3blBaeT Ha To,
qro B aHanu3upyeuou o6paoqe npucyrcrBypr amrrena x MT
B KOHqeHTpaqUn
Bbrue n0poroBor4.
Orprqarensxuri pe3ynbrar. BHqeneHue g tectosoil sote
nraHurera ronuxo oAroi nuuu poaoeo-$nofleroBolo qBera
Ha ypoBHe MapxnpoBxr4 C (xomponu) caugerenscrayer o6
or-
pnqareflbHoM pe3ynbraTe aHanu3a, To ecTb yKa3blBaeT Ha T0,
qro
B
x MT
aHaflu3r4pyenltou obpaeqe KpoBr4 r(oHqeHTpaq[l aHruren
grxe
noooroBoro 3HaqeHrg.
e
OOO IMEI-SKCflPECC-AilA|HOCTI/Kb no
a
aApecy:
88, xopn. 3, o$ttc 100;
119313, Mocrea, Ilexrrcxutl np.,
renegor/Qaxc: 8 (499) 138-00-79, (499) 138-19-91, e-mail:
med@progbio.ru; info@domtest.su; www.progbio.ru; www.
domtest.su,
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