llrrqma3- O5E35ONilBAH]4E B TEPANEBT]4I{ECKO]4 CTOMATOfl O!'IqECKOfr NPAKThKE DM. po0Be Hra .rM lr,!R nu- UE 03, Eyrunoocxni Arercangp Banepremr, HaH[uaT rcllq[florlrx ttay[, Aoqeilr 2.i raQe4pu repanerumcltol cloilaTofioffI Eenopyccroro rocyflapcTBeflHoro ilefllqlffifioro yrrrepcmera, ilnncn Saxapora llpma AnaroaleBfla, accrclerT 2-I ra$egpbt repaneul+croi cTomlo,loill ilellqlilcfloro prrepcrera, lllmcn Eempyccnoro rocyflapcToeHfloro rc- Borolremq finrtpril lleon4omq, l0-i Bpaq-croraTonor ltl[[c[, ropopron cToilaToflorilqecfio[ nomxnmrru, Alexander Butvilovsky, Eerapycr PhD, Asociate Profesor of the 2nd of the Irina Zakharova, of lhuapeutic Depailment Belarusian Stah iledhal Dentistry University, ilinsk Assistant of the 2nd lhpartment of Therapeutic Dentistry of the Belarusian State iledical University, itinsk Dmitriy Ualadkevich, Dentist of the t0th City Dental Clinic, ltinsk, Ane$hesia in therapeutic dental Belarus practice Pespue. B nexquu npeqcraBneHa xapaKTepucruKa MecTHHx aHecreruKoB, IUAIB MecrHNx auecresurt u BapuaHTu urn, ucnohayeMux Ha auiynaropxont repaneBTuqecKoM u oproneAuqecKoM croMaTolnruqecKoM npueMe. Paccuorpeuu npeuMyqecrBa apTuKauHa KaK MecrHoro aHecreruKa au1opa u aonpoc o1ee6onueauun npu neofiparuuou BocnafieHuu nyfibn*. Kngeeue cnoaa: aHecreaufr, 6on4 crouaronorun, apTuKauH, nuAoKauH, MenuBaKanH. Corpeuennar croMarororrs. Sunmary. - 2019. - J\!2. C. 13-f6. - The lecture presents the characteristics of local anesthetics, types of local anesthesia and variants of needles used at an outpatient therapeutic and orthopedic dental reception. The advantages of afticaine as a local anesthetic of choice and the issue of anesthesia in,the non-reversible inflammation of the pulp are considered. Keywords: anesthesia, pai n, dentistry articaine, lidCcaine, mepivacaine. Sovremennaya stomatologiya. fi a6ora epaqa-cToMaTonoTa 3aHa pc vacrurtr npoBeAeHueM MecTHoro I c6ee6onuBaHufl, nocKonbKy npoTocBf, rcnb .e.eruf, 6onuuJuHcrsa sa6oneeaHilfi x TrE1r pra BKrIoqa0T gran o6es6on[Ai{ecre3uf, no3Bonf, er noBbtctrrb rpoooAr4Moro reqeHun. SQSex"TG{!F ;]€cre3uf, noMoraeT cHH3LtTb pr4cK mrr raffi "!fr i FccHam€cxr4x ocroxHeHufi , cengaHHurx :1rErcra..ErcflanbHbtM cTpeccoM, xoropuM Gbtcrr naqI4eHTH, a TaoKe peuilTb ST[I- rwrE to6rcuy npravuHenun 6onu. Hacro ilEElEG {H(ilMtrr e${exruenoro o6es- furcfl, Enf,ercn KptrrepueM BbtcoKoro nffiJo€rl,Blvut narc'-- Bpaqa B npeACTaBneHilU h-4]. -,l pr-ipr llreflln lrf,r,E .=€ruf, fus rc rmssi, OIHOCIITeJbHO npe[My- aHecreguu: oTcyrcTB[e c8f,3€ll{.{bxc aHecresuefi; ltr*{E?b ruroi 4uarnocn4Kt4, onpeAe- f,lliI ryHIa,(IoB t4ToqKu anilKanbHoro sprTr. Effinrfpcu Ha ou.lyqeHun na- - 2019. queFna; orcyrcTBueoneuenun - N2. - P. 13-16. ry6, lt1eK, f,3bxa noBblueHilo qacToTbl t ctlltbt cepAe'{Hbtx coxpaqenufi , aprepilanbHoro AaBneHufl , nocre reqeHuf, o6ecneqilsaer xou$opr. Ognaxo n6 xaxgurfi u3 npuBeAeHHbrx ap- ypoBHfl rnoKo3br ryMeHToB M0xH0 npuBecTu KoHTpapryMeHT: yBenuquBaeT pLrcK Bo3HrrKHoBeHilfl HeoTfl - 6onu npil neqeHulr conpoBoxAaercfl 6onee sHcoxr,rMr/ pr4cKaMu ocnoxueuufi , npu TqaTeflbHolvr c6ope aHaMHe3a u npa- B KpoBt4, rtTo, HecoMHeHHo, 0x- uurx cocroRnuil Ha npueMe. Sonegnennocru np[ fleqeHuu raxxe Qopruupyer cTpax TpeBoxHocTb naqueHTa, L{To BeAeT K u oTKa3y eunuHofi TexHuKe npoBegeHufl aHecTegu[ pt cKt4 ocnoxHeHuf, MaJIbt; or o6paqenun - A[arHo3 AonxeH 6uru nocraenen go HaqaIa fleqeH14fl; ogoHrorennoil ux$exquu [1, 3, 5]. Taxuu o6pasoM, neqeH[e Ha npueMe - coBpeMeHHoe o6opygoaaHue no3Bo- nf,eT onpeAefluTb cynepKoHTaKTbr Lr To'{Ky K cToMarorory nporpeccupo- BaHuo naro.noruu u $opurupoaaHuo oqaroB y Bpaqa-croMaTonora 6eg aHecre3uu AonxH0 npoBoAr4Tbcf rolbKo npu Hanuquu npo- anuKanbHoro oTBepcTnfl 6onee rovno, veu n4Bonoxa3aluI, cy6uexruaHue oqyqeHiln nallueHTa; or aHecre3uu nra6o - oHeMeHue ry6, qex, figHKa He flBrFeTcfl o6noarenunuu npu3HaKoM e$Qexrraanofi 6orcgHeHHocru BMeuJarerbcrBa. 3a4a,au e cnyvae orxaaa naqueHTa npr,r yoepennocru e 6€- ffieafionunflnn 1. fioeHureHue KaqecrBa oKa3aHuR cro- aHecTestrtr. Taxxe neo6xoAt4Mo yt{uruBatu, vto 60TerbcTB npuBoAr/T K yBen[qeHuo ypoBHn MaronoruqecKofi nomoqu. 2. CnuxeHue p[cKa pa3Burun o6qux ocnoxnenufi, cBt3aHHbtx c ncuxogMotlt/o- aApeHaflHHa B KpoBr/l, cooTBeTcTBeHHo, HarbHbrM cTpeccoM. fl e3HeHHoCTb CToMaTororuqecKLtx &ft-:-\-l BMeuJa- ll l-llrrqnr 4Fal,I. il Amtrarx Jlnaomr Sqnrr*rprx rc ywrcr s$QeKT aHecTe- i.,ralt{o ylJxmer ee eperr,rn [1, 5]. i-tsotrmrc orrcrxrb npoTtrBonoKa3atI { @FlE a€CTe3},il4 C Ba3oKOH- 5ff( rxr*nro cErforrL i " Hesa&ro nepeHeceHHbtfi nxQaprr EAa 2 fhomtauas rETarynr- &w[rsn ftuMKapAt4n u Apy- X 3aqrraryrut+nr rnayKoMa. 4 CqfrmryuJ1af, Tepanun uxru6uro- 45S axrxcxe pr llA0 ur rpqxKnlrqecKuMu aHTLr.Erpecffrr5. Epm;tua &rua c nosuluJeHHofi Pilc. 1. ArrusHocTb aHecreruKa B 3aBucrlMocrr4 or pH (7,4 - pH uex<nero+oi cpqqr) lErnrerucrhD x cyrrQurarvr (cynuQur- crf.ircropu agpexanr,tra). ni 3. l4s6aeneHue naqueHTa or 6onu. Mecrnue aHecreruKr4 - fl eKapcrBeHHHe BeqecrBa, BpeMeHHo nogaannoque eos6yAilMocTb oKoHrraxuil ryacraurenbHHx HepBoB r,r 6noxr,tpyror4r,te npoBeAeHue [MnynbcoB no a raKxe cnoco6xue MecTHyro 14flu peruoHapHyo nG HepBHbrM BoroKHaM, tsbrsHBaTb Tepo qyBcrBr4Tenunocru [4, 6]. Pagnuqaor cfloxHbre e$upur, cnoxHbre Csseu*anue c &nxan. Axecrer: peqefrropor.. uro6u orxpuru xarpreari raxan. tler 6onuue cnoco6xocru aHecrerf,a AOnxeH CBR3HBaTbCR C 3HBarbcR c 6emarn, ce rfl fi/rreltr€e 6errn y + rrKarHa - 95%, rernarara - 851, nuAoxaxHa - 65%. aHecre3xf,. CaRatnalc c Ocofiemrcn wMJ- un- kmn 6" crarorffIr Qopa neueuo.trofi xego(rrcpQpus). 7- ilero+rponayeuoe noBb[ueHue ap- reFIDlEro ga8rEiffi. 8" tleranponpye*rfi runeprupeos. 9- fbonponpye*,ti caxapxrfi gua6er. t. {Deo4ouo4rroua. 11. BoryI naqperra go 4 ner. fhr rcmogrucru r 6es EErrxoxcrpilKropa npeAnoqTeHue srr agn €rry 6es agpexanuxa (Ynurpa- HOBOKAUH. Bce HHe aHecreTrKH pa3pylrnErcn B ,B€rf. Apruxaux, KpoMe roro, ntarrnrpyerctr ecrepa3aMlr nra3Mu xposf,(9s%), rrub Cnoxnwe auugw : nuAoKauH; TpuMeKauH; MenuBaKauH; npunoKauH; 6ynuaaxaun; tl€HetX. t{eu uenuue BpeMf, nonyBHBegerm axe llerrereerg)F-91. lfuDtEHrH @BpeM e HH H x n pe n ap aroB 0Tr/lA0KauH. creruKa, aMugbr, a raxxe ruoSeHoBHe aHecreruKrr. Cnoxuue eQwpu: AuKauH; aHecre3uH; TuoQenoewe (co cnoxxofi eQr,lpxofi r,r cnoxuofi auugHofi cansuo): apr[KauH. S$Qerruenocrb MecrHbrx aHecreruKoB n 6esonacHocTb aHecTe3uu 3aBucfiT or geficreyroqero Beu.lecrBa (pKa, xupopacTBopr4Mocrb, cBfl3uBaHue c 6enxauu, oco6enxocru eueeAeH[n) u Sopurynur / 5o/o apTnKaUHa l,lHaKT!4BXpyeTCR B reu 6egonacxee ero nplrretefle (uenuu:e prcK nepeAo3upoaxu). Bpeun nonyBHBeAeHus y nrrAoKauHa 114 - y apruKalrHa - 29 urx, 96 ut,tx, y MenuBaxalHa - r<ar.r & npoBeAeHun aHecre- nr6o Meilaaxauny (Cr<anAonecl apnKatrffi - aprlilculr (10 ur s 1 un pacraopa - To ecrb 4% pacreop); - BOAa AXCTUTlnlrpOBaHHaf, ; - uux. lrlcxogn us caoilcrB npenaparoB, aprt,tKauH flBrrneTcfl npenaparoM eufopa na au6yna- Harpun xnopr,rg (4nR usoronuvnocru pacraopa); - coruHan xlrcrlom luru ruApoKcl4A HaTpufl TOpHOM CToMaTOrOrUqeCKoM npueMe, n0pnA cKonbKy uMeeT npeuMyqecre: 6ucrpoe go sa4axxoro pH; no- HacrynneHue aHecresuu (exonouun pa6ouero cToflHHafl BeIUqUHa, f,Bnf,lou.lafcf, xapaK- apeuenu), AocraroqHaf, rny6una u npoAonxuTenbHocrb gefi craun gnn 6onuuuncrea 1:100000, 1:200000, 1:400000 co cra6unu3aropoM narpnn uera6ucynu$r,rrour 6penga (ra6n. 1). pKa - roxuaHTa fquccor{uaquu - repucruxofi KaxAoro axecreruxa. 3ro 3HaqeHue pH, npu KoropoM 50% uonexyn aHecTeTuKa HaxoAf,Tcf, B aKTL|BHOM C0crorHrnr (pr,rc. 1). XtWt*tmonpegenner HocTb MoneKynbr npoxoArrTb r{epes KrerKu. TeM leu nyque cnoco6- nenl6pany 6onuu:e xupopacTBopr4Mocrb, aHecTeTr4K npoHuKaeT B HepBHHe xnerxu (guuJe eS$exruaxocrb - HyxHa gosa). XrapopacrBopr,rMocrb MenuBaKa[Ha paexa 1, nuAoxa[Ha - 4, apruMeHblrJurfl - CTOMATOJIOTUqECKLIX ToKcrrr{Hocrb (4o/o - BMEUJATETbCTB, H143KZIR nuexuil purcK pa3B}fluf, ocnoxnenufi), Manoe BfluflHr4e Ha qacrory cepAeqHbx coxpaqeHrail [5]. llocxonuxy apTuKa!{H o6nagaer uecrHbrM cocyAopacuJLrpf, rorlr4M gefi creueu, B cocraB aHecreruKa KoHcTpr/KTop - go6aennor easo- aApeHafl uH (entane$pun). Agpexarux cyxaer cocyAu B Mecre BBe- AeH[fl , npennTcreyer 6ucrpoMy paccacH- 17. Burcoxyro xr4popacTBopr,rMocTb BaHUlo Aeno aHecTeTltKa B Mf,rKlitx TKaHflx aprurauna o6ecneiusaer TuoQeHoBoe KoJb- n nponoHrupyer geficreue aHecre3xx. Heo6xogr,ruo o6paruru BHl4MaHue, r{To KauHa qo B ero xuuuqecxoil cTpyKrype. - conu aApeHafluHa B pa3BeAeHuu ; - SAIA (crd6urra3aTq uoHoB MeraflnoB, KG Toptle Moryr RrAeftErbcn ue crexna xapnynur); napa6exu (onr{r,tonanuno). - Epsryoexa npeflaparoB aprrKarHa MaxcuuanuaR pa3oBan Ao3a - 1 xapny- na npenapaTa apTuKauHa na 10 xr uaccur Tena naqx$rra. Baxno, wo eeoAurb naq[eH- ry uoxno xe 6onee 5096 or uaxcurrranuxofi pasoeofi gosu. OAqrc npaouna npoBeAeHlrf, uHbeKqxormol anecreeuu . fl pegeapurefl bHaR annruKaquoHHan aHecTe3ufl. . O6pa6orxa Kapnyflbr 70% cnuprour. llmqm r BCTE- ri'; upaBHuTenbHaf, xapaKlepucr riKa aHecreTilKoe no geficraynqeMy BeqecrBy ypoBHe BepuJt4HU luexsy6nofi neperopoAxr,r. Konuqecruo npenapaTa apruKauHa t, sl. Ioxaearenu t:t3a- Ilngoxaun Menugaxaux Aprurarx 7,9 7,6 7,8 0,2-0,4 un, XipopacTBopt4Mocrb hnehaaHue c 6enrauu, Apy- o/o 114 29 4 5 -.. .,'-*lcTb 2 1,7 1,5 2 2,4 3,3 30-60 45-90 60 . lporpenapupoBaHue .IE}tr B rpoqecce npo- ITNH B MffKI4X TKAHf,X. rmran). (bote r atRU aHecregxu - r$mrpaquoHHafl B cromaroro , npoBoAHt4KoBafl , ilp?- {ecl ATOB )a)cT14 o HH af, aH ecre e u n. llpu- G*nErcn Mf, neqeH[fi sy60e eepxneil u +md qenncru. l4tuexqun npoBoAl4Tcf, : a=ca6ynnpnoil croponu, BKon urflbl t rE@roAHyto cKnaAKy, npoABuxeHue r ]@llf,) BepxytxKt/ KopHfi , noIoxeH[e []Ib rJl yrnou 45o K Kocl4. Beognrcn &^3-3 8 rn npenapaTa apruKauHa Ha - rri B TepaneBTuqecxoil nparruxe l€re(s c opanunofi cropoHbt He npory:r [1. a]. l;rl oruerurb, r{To Anf arqeKBarHofi E,EII UOnf,pOB ttUXneft qeI|ocTu, He- rphfi HUU '0,O6 nn a6r,rt; t, K0- hjrrr: - rrrmr.rexr,ri -/_ *.ts- + flpoaognuxoeafl aHecresue. B repaaeqeH[f, MonRpoB nuxnefi qenocrtr. [IJnpuq pacnonaraor Ha ypoBHe npeMo,rfipoB unu nepBoro MonFpa npoTr4Bono- noxHoil -::;iiffiffir* rrHbeKLltrt4 B narepaflbHbrfi cropoHu, BKor urflbr cxar rpunoBuAHo-Hrrx- neqenpcrnofi cKflaAKu Ha rpaHuLle ee cpegnefi n nuxneil Tperu, npoABuxeHue Ao KocTrr. Konuqecrgo apruKauHa Ha AaHHyro rrHbeKllrno or 1,5 po 2 run [1, 4 5]. l7 epuogonran oH afl aHecres u f,. fl annuil B[A aHeCTe3UU npUMeHf,eTCf, Mfl neqeHufl ecex sy6oa. K nepuogoHralunoil anecresuu npuHfTo oTHocrrTb [HTpacenTanbHylo u uHTpanuraMeHTapHyo - l4nrpacenrarbHafi aHecre3ufl - BKon urnH noA npflMbrM yrnoM K noBepxHocTt/, nocepeAuHe MexAy geyun sy6auu Ha % T- (* flpoqegypa npaKTuqecKu 6eo6oneg- / OrcFcraue oHeMeHufl rrrnrxux nanefi. / Munuuanunoe uqecrBo aHecreTuKa Kofl cHlrxaer Bepof,THocTb no6oqnux peaxquil, qro BaxHo npu Hafluquu conyrcrayoqeil naToll0ruu. / BosMoxHocrb fleqeHuf, sy6os uerupex KBaEpaHTOB B 0AH0 noceqeHue. Orparuqeru,rn nepuogorranuxofi aHecTBl{U: . Hanuque naTonoruqecKoro KapMaHa. . 0crpue unu o6ocrpexun sa6oneeaHuil . Hanuque B aHaMHe3e oHAoKapAilTa g]. [5, 6, O6ee6onrBaHre npt neo6pauuux aflbBeolrf,pHoro Hepea 6es npu3HaKoB Boc- nareHufl xone6nercs or 85% go 90%, e ro BpeMf, KaK npu BocnafleHuu nylbnbt MoxeT onycKarbcn nnxe 20o/o. 3ro o6ycnoeneno cyu.lecTB0BaHueM TeTp0AoT0Kc14H-pe3ucTeHTHbtx ]4OHHUX KaHanoB, KOnUqeCTBo h -lnH fiHTpaMrai/enrapnori aHecTe3il[ r' HEHHA. He BcerAa BocnpuuMr{r4Bbt x ruecrxofi ane- Koropbrx Bo3pacTaeT npu aocnanexuu. HHe xaHanH npaKTuqecKu xe !gn- 6noxupynrcn MecTHbtMl4 aHeCTeT[(aMU. Cyqecreyer HecKonbKo BapuaHroB pewenua gannort npo1neuu rxaroaar{{ccttnx oco6cxromra nar{rerTa :j : --: --a,,-a=- -.:_-. Maxcuuanuxui e0Qerr pa3BuBaercn t,r gnurcn 20 uunyr. cre3uu. Ycnex o6es6onuBaHur HtrxHero Xorcrxsf; rxn: anarragHr aaNrilrlrt pacTlopa x : / cpa3y nyflbnt{riu Cornacno KnuHuqecKuM t ccJlegoBaHunu, sy6u c ocrpbrMr,t cocrof,H14fMt4 nynbnbt *0,01-0,I nn - - Munuuanuxuil narerrnufi nepraoA (<1 MapruHaflbHoro nepuoAoHTa, aHecTe3uD. '0,06 un / rrrr,ln). negruqecxoil npaKTuKe npuMeHRercfl *$nbrpaUu )HUe o6xogurvro npoBecTu npoBoAHllKoBylo l4llrr AaR 'rEmG{TaIbHafl. lcTe- llpenuyqecraa neprogonanuxof, nepu0A0HTanbHylo aHecTe3up. . Ooor<parrroe ucnonmoBaHile uill. t6er. BBoAl4TcR MeAleHHo, cKopocTb 0,12-0,18 un I 7 cex Ha oAuH KopeHb. fiocne aaaepuleHufl trHbeKllrn4 [rny MoxHo AocraBaTb cnycrn 10-15 ceBBeAeHuf, aHecT$]t1{: . lcilpaquoHHar npo6a (axruaxan unu 3. Axecrerux xyn4 (pr,rc. 2). aHecreguu, 6eg @rcrpxl$opa $u- ) ap- 17 95 4 ,[!rcruocru xsofi 1 75 96 Conouexue arr[aHocru/rorcuqHocru lHT14- 4 65 lecreanpyor.qan aKruBHocrb M14H. iuro- eAo- - - l,'lnrpanuraueHTapHan aHecreguf, aHTucenruqecxan o6pa6orxa ey6ogecneeoil 6oposgxra, BKon t{rnu nog yrnou 30o x gnuuoil ocu ey6a, npoABuxeHue Ha 1-3 trru Ao orJ.lyrJ.leHur conpoTuBreHuf,. xoHapKT -- - o6uev aHecTeTuKa Ha - flpegeapurenurufi npueu ra6ynpoQena nu6o gpyroro necTepouAHoro npoTt4BoBocnaruTerbHoro npenapaTa BHyrpb. Ta6tu4a 2 Kapnynuxue [rnH Mf, aHecr$r,t{ Trnopasmep mnu (eHyrpenxuf, Ar,railep annn) B ra6nuqe 2 npegcraaneHu urflH B PE rqflR aHecTe3uil KapnynbHbrM unpuqeM. - Bneunrfi O urnu x plrutarrnu, Brg anecresuu MM OorosHue HanpaBreHln npoQnnamuxu ocnoxnenufi npu npoBe4eH[[ aHecresul 30G x 12 uu 0,3x 12 (roporr<an, ToHKan) 30G x 16 uu 0,3x16 (xoporxan, ronran) 30G x 21 r'irr'ir 0,3x21 (cpegneil 4nranu, ronr<ar) 30G x 25 r',rr'it 0,3x25 (cpepner,r Mr,rnu, ronxa.a) r,rHTpanuraMeHTapHafl 27G x 30 t,tt',t 0,4x30 (Mr,lHHan, 27G x 35 uu 0,4x35 (Anr,tHHan, ToncTaff ) 27G x 38 tutu 0,4x38 (gnr,lHHan, Toncras) Tofl / Tu.larenunuril c6op anauneea co cBoe- BpeMeHHbrM 3anoflHeHueM ueguquncxofi AOKyMeHTaLlur4. un$unurpaquonnar / 0r{enxa o6u.lero cocronHrlf, naLl!4eHTa u ero AuHaMilqecxuil xonrponu. r' Paquonansnufi au6op MeToAa aHecre- cras) np0BoAH14K0Bau 31414 r' il neKapcTBeHHoro cpeAcTBa. Koppexrnan rexHilKa aHecre3uu. 3axlpqeuue - Kotu6unaqun fluauerp (anyrpennuil) n,tecTHbrx aHecre3rail (Hanpr,t- 6onsuLe AaBneHue npu [HbeKllnr rI BHUJe BepofTHOCTb nepeKpbrTl4fl TKaHf,- - Kour6unaquf, ?a3flur{Hbrx npenaparoB aHecreruKa (crporo B coorBercTBr4rr c rrH- - cTpyKqueil npou3BoAurenn) [6, 7]. Bu6op urnu gnfl aHecrmuti flnuna -ueu Kopoqe gnuna, reu 6onee - ,Quauerp (napyxnurt) - ueM Tonqe ilrna, TeM oHa 6onee ynpaenf,eMa !r MeHbue pucK nonalaHun BHyrpb cocyAoB, Ho TeM 6onesHeHHee [HbeKquR. rou, cnoco6creyer HopManbHoMy ncuxooMo Cpee: gna nerKoro npoABrrxeHun noA HarqKocrHrrqy - xoporxufi (70') r,t cpegnr,rfi r_ll4oHanbHoMy cocTofiHr/lo KaK Bpaqa, TaK u nefi - gnunrufi (10-20'), Mfl cHuxeHuf, 6onesxexxocru - Mynbrucpea (cnoxuufi, rpoilnoil). yBepeHHocl/ Bpaqa B 6eg6onesHeHHocril BMeuJarerbcrBa (c cornacun naquenra). uecrtoro o6e- - - 1997 -T.76, C.25-29. 3. 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Ko$nrm rrrepecoa Cornacxo sanenenuo aBTopoB, xoxSnurr uxrepecoB orcyrcTByer. llocrynuna 08.11.208 llpuunra e neuan 15.03.2019 Address lor conespondence 2nd Depafinent of Therapeutic Dentisty Belarusian State Medical Univemity 28, Sukhaya steet Minsk 2200p4, Republic of Belarus drone: + 375 17 200-5t-36 Alexander Butvilovsky, e-mait alerbutv@ ramtrler.ru