. 2013. 1. . 175–178. 615.322:582.916.6:547.814.5:543.422.3 (FORSYTHIA INTERMEDIA ZABEL.) © * . , . , . , 11, , 357532 ( . , ), e-mail: [email protected] . - . , 70% . (2,05 0,052%). : , , , . , , - , . . . (Forsythia intermedia Zabel.) (Oleaceae) , . , , - [1]. . . - , , , , . , , ( ), . - , ( ), ( , , ). . – , .: (8793) 39-10-87, , e-mail: [email protected] – 2009 . , . – , e-mail: [email protected] * , , , , , . , - 176 . , , . , , . 3–9 , 5 , 1,5 . , 7–13 . , - . , . , 7 . , - . . : 30, 50, 70 90%. . , , , . , . . . XI, - , [2]. 1,0 150 ( 30 , ) [2]. 30 , . 100 . - 30 . . - . . , 5 . 25 95% 2 2,5 , 2%- . 10 10 0,1 95% ( . 25 0,1 10 ( 2,5 , ). 95%95%- 10 - ) [3, 4]. 30 -2000 10 : 0,05 410±2 ( ( . ) , - ) 100 .1 25 , ( ). : X A a W W V A a V W W x % cm x1 cm x ax x2 cm1 acm cm 2 100 100 (100 A a 1 100 100 , A a V (100 ) x ) cm cm x ax … Ax – x – ; Acm – cm – , ; , ;V – cm , , , ; 177 ; , - , ;V – ; W 1, W 2 – ; Wcm1, Wcm2 – , %. – 1. 1 , 1. 70%- . , ,% . 30 50 70 90 2. 2 ,% 1,57 1,62 2,05 1,65 , - 2,05 0,052%. 2. , 1 2 3 4 5 =408 0,405 0,419 0,411 0,413 0,397 cm, =410 ,% 2,03 2,10 2,06 2,07 1,99 0,452 – 70%- =2,05 S=0,0418 S =0,02 =0,052 = 2,54% . - (2,05 0,052%). 2,54%. 1. 2. 3. . : 2 . : ., . ., 2004. . 1. 840 . : 2 . 11., . ., 1987–1989. : . 1, 2. . ., 4 2011 . 1969. 168 . 4. ., . ., . . , 1987. 193 . 178 . , . , . Leonova V.N.*, Popova O.I., Savenko I.A. DEFINITION OF FLAVONOIDES IN LEAVES OF FORSYTHIA INTERMEDIATE (FORSYTHIA INTERMEDIA ZABEL.) Pyatigorsk State Pharmaceutical Academy, pr. Kalinina 11, Pyatigorsk, 357532 (Russia), e-mail: [email protected] As object of research used of forsythia intermediate leaves. The purpose of work was definition of the sum flavonoides in forsythia intermediate leaves. Are carried out researches by definition optimum extragent as which 70% spirit ethyl have been chosen. The method of differential spectrofotometry in investigated object installs the quantitative maintenance of the sum flavonoides in recalculation on routines (2,05±0,052%). Keywords: forsythia intermediate, leaves, flavonoides, differential spectrofotometry. References 1. 2. 3. 4. Shreter A.I. Prirodnoe syr'e kitaiskoi meditsiny [The natural raw materials of Chinese medicine]. Moscow, 2004, vol. 1. 840 p. (in Russ.). Gosudarstvennaia farmakopeia SSSR: Obshchie metody analiza : v 2 t. 11-e izd. [State Pharmacopoeia of the USSR: General methods of analysis: in 2 vol 11 ed.]. Moscow, 1987–1989, no. 1, 2. (in Russ.). Barkovskii V.F., Ganapol'skii V.I. Differentsial'nyi spektrofotometricheskii analiz: spravochnik. [Differential spectrophotometric analysis: a guide]. Moscow, 1969, 168 p. (in Russ.). Krasnov E.A., Berezovskaia T.P., Alekseiuk N.V. et al. Vydelenie i analiz prirodnykh biologicheski aktivnykh veshchestv. [Isolation and analysis of biologically active substances]. Tomsk, 1987, 193 p. (in Russ.). Received July 4, 2011 * Corresponding author.