ФУНКЦИОНАЛЬНАЯ МОРФОЛОГИЯ ОРГАНОВ ИММУННОЙ

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.
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,
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.
,
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.
,
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.
.
,
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,
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.
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.
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,
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),
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7
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,
.
,
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,
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).
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,
,
.
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,
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:
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.
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.
,
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,
-
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(
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.
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Ki-67,
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.
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Statsoft Inc.99, USA).
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,
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,
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»
6,4% -
,
,
,
,
-
.
,
.
,
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.
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(
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-
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).
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,
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.
-
IgM).
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10
19,2%
,
,
-
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, 66,7% – 1-2
33,3% – 2-10,5
)
-
-
.
,
,
.
-
,
–
,
.
,
.
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,
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.
.
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,
.
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,
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,
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.
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-
,
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2-3-
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.
,
,
.
-
:
-
CD4+/CD8+,
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IgM
,
«
IgG;
»
.
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-
,
-
,
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-
,
-
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);
-
- ,
,
-
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.
.
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,
,
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,
,
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),
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,
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.
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:
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.
-
:
;
CD4+/CD8+,
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-
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IgM);
;
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-
;
;
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,
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«
-
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).
,
. II
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,
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.
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50
,
-
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;
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.
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3.
;
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.
-
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.
,
.
-
–
(II)
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,
.
,
,
,
-
-,
,
.
.,
4. . 50.
. //
.,
1.
. 2001.
.-
.
. 2004.
.,
4.
.,
. 2002. . 64,
.
. 1. . 3.
:
.
.
. //
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9.
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.,
. //
..
.,
.
-
. 2001.
.
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.
.
.
,
, 2004. 19 .
10. Arora P.K., Fride E., Petitto J. et al. //
Cell. Immunol. 1990. Vol. 126. 4. P. 343.
11. Des Jarlais D.C., Friedman S.R., Hopkins W. // Ann. Intern. Med. 1985. Vol. 103. 11.
P. 755.
12. Friedman H., Newton C., Klein T.W.
// Clinical Microbiology Reviews. 2003. Vol. 16.
2. P. 209.
13. Kringsholm B., Christoffersen P. //
Forensic Science International. – 1987. Vol. 34.
4. P. 245.
14. Mathew J., Addai T., Anand A. //
Arch. Intern. Med. 1995. Vol. 155. 15. P. 1641.
15. McCarthy L., Wetzel M., Sliker J.K. et
al. // Drug Alcohol Depend. 2001. Vol. 62. 2. P.
111.
16. Rezza G., D Egidio P., Lepri A.C. et
al. // Addict. Biol. 1997. Vol. 2. 2. P. 201.
17. Risdahl
J.M.,
Khanna
K.V.,
Peterson P.K., Molitor T.W. // J. Neuroimmunol.
1998. Vol. 83. 1-2. P. 4.
18. Toccanier M.F., Kapanci Y. //
Virchows Arch. A. Pathol. Anat. Histopathol.
1985. Vol. 406. 2. P. 149.
.
.
. //
. 2002.
.,
8.
26,5%
1.
-
. 21
.
.
.,
4. . 21.
.,
. //
6.
-
III
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. //
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-
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.,
.
.,
.,
. 2002. . 64,
4.
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.-
. //
. 89.
IgM);
-
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.
6 2009
51
FUNCTIONAL MORPHOLOGY OF IMMUNE SYSTEM ORGANS
AT OPIATE NARCOMANIA
Gasanov A.B.
«Forensic medical expertise and Pathological anatomy» Unification, Baku, Azerbaijan
Morphology of the organs of immune system is investigated in 219 autopsy cases, which
died by reason of opiate narcomania. HIV-infection was excluded. Revealed immune disorders
are differ according to staging of development and characterized by inversion of immunoregulation index, atrophy of the thymus and T-zones, follicular hyperplasia of B-zones with broken
architectonics of lymph nodes in 37,4% of cases, development lymphadenopathy and
splenomegaly in 26,5 % of cases, as at HIV-infection. Atrophy of T-zone and hyperplasia of Bzones (especially in spleen and hepatic hiliar lymph nodes) intensify at HBV and HCV infection.
Keywords: opiate narcomania, immune system morphology.
6 2009
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