47 616.89–008.441.33–091:612.017.1 . « », , 219 . , - . , 37,4% , 26,5% , - . . , : , - . 219 , (213 16-38 . 6 ). - - , . NK, 16]. , , [1, 4, 7, 10, 11, 12, 14, - 65 , , (58 ), 21-42 7 – 20 , , . , 3 16-35 – , [2, 3, 5, 6, 8, 9, 13, 15, 17]. « » , 80- (17 ). [18]. , , . , - - [7], , [2, 9, 13]. : 1 - - , 10,5 , 1. 2- 2- - - 88,6%, . 23,7% . , 6 2009 , - 48 ( , , ), , ( CD4, CD8, IgG, IgM . IgA) Ki-67, - ( , , , .). . ( , ) , , ( «Statgraphix», «Stadia» Statsoft Inc.99, USA). , , , - 38,8% 12,8% – , « 8,7% - , 10,9% - » 6,4% - , , , , - . , . , ( . 53,8%. ( 100% - , 6,2% – 26,5% ). 98,6% 97,5% 1 , 100% - 2-10,5 . - IgM). 37,4% 1 10 19,2% , , - 98,7% - 1-2 - ( 16% 1 , 66,7% – 1-2 33,3% – 2-10,5 ) - - . , , . - , – , . , . – , 80- . . - » [18] , . - , , - , . - ) [16], , – . , - , 6 2009 49 2-3- 93,8% - – 0,5-3,2% . , , . - : - CD4+/CD8+, - IgM , « IgG; » . ( - , - , ) - , - [2, 6]. ); - - , , - , . . - , , – , , , , , – , 1 (I (II ) ), 2- 1 ( ), ( 210,5 ), ). , - « ). - » III , (III - . .I - : CD4+/CD8+; . - : ; CD4+/CD8+, , - ( IgM); ; - - ; ; – , - , ( » « - ). – ). , . II - , , , III , . 6 2009 - 50 , - 98,6% ; ( . 2. . 9. 3. ; 37,4% . - 7. . , . - – (II) (III). , . , , , - -, , . ., 4. . 50. . // ., 1. . 2001. .- . . 2004. ., 4. ., . 2002. . 64, . . 1. . 3. : . . . // . , . 6. . 6. 9. , 2002. 27 . ., . // .. ., . - . 2001. . : . . . , , 2004. 19 . 10. Arora P.K., Fride E., Petitto J. et al. // Cell. Immunol. 1990. Vol. 126. 4. P. 343. 11. Des Jarlais D.C., Friedman S.R., Hopkins W. // Ann. Intern. Med. 1985. Vol. 103. 11. P. 755. 12. Friedman H., Newton C., Klein T.W. // Clinical Microbiology Reviews. 2003. Vol. 16. 2. P. 209. 13. Kringsholm B., Christoffersen P. // Forensic Science International. – 1987. Vol. 34. 4. P. 245. 14. Mathew J., Addai T., Anand A. // Arch. Intern. Med. 1995. Vol. 155. 15. P. 1641. 15. McCarthy L., Wetzel M., Sliker J.K. et al. // Drug Alcohol Depend. 2001. Vol. 62. 2. P. 111. 16. Rezza G., D Egidio P., Lepri A.C. et al. // Addict. Biol. 1997. Vol. 2. 2. P. 201. 17. Risdahl J.M., Khanna K.V., Peterson P.K., Molitor T.W. // J. Neuroimmunol. 1998. Vol. 83. 1-2. P. 4. 18. Toccanier M.F., Kapanci Y. // Virchows Arch. A. Pathol. Anat. Histopathol. 1985. Vol. 406. 2. P. 149. . . . // . 2002. ., 8. 26,5% 1. - . 21 . . ., 4. . 21. ., . // 6. - III . 2001. . // 5. - , ., . ., ., . 2002. . 64, 4. ( ) (I), ., .- . // . 89. IgM); - 2. . 6 2009 51 FUNCTIONAL MORPHOLOGY OF IMMUNE SYSTEM ORGANS AT OPIATE NARCOMANIA Gasanov A.B. «Forensic medical expertise and Pathological anatomy» Unification, Baku, Azerbaijan Morphology of the organs of immune system is investigated in 219 autopsy cases, which died by reason of opiate narcomania. HIV-infection was excluded. Revealed immune disorders are differ according to staging of development and characterized by inversion of immunoregulation index, atrophy of the thymus and T-zones, follicular hyperplasia of B-zones with broken architectonics of lymph nodes in 37,4% of cases, development lymphadenopathy and splenomegaly in 26,5 % of cases, as at HIV-infection. Atrophy of T-zone and hyperplasia of Bzones (especially in spleen and hepatic hiliar lymph nodes) intensify at HBV and HCV infection. Keywords: opiate narcomania, immune system morphology. 6 2009