SURVEILLANCE REPORT HIV/AIDS surveillance in Europe 2014 www.ecdc.europa.eu www.euro.who.int HIV/AIDS surveillance in Europe 2014 HIV/AIDS surveillance in Europe 2014 Suggested citation for full report: European Centre for Disease Prevention and Control, WHO Regional Office for Europe. HIV/AIDS surveillance in Europe 2014. Stockholm: ECDC; 2015. Tables and figures should be referenced: European Centre for Disease Prevention and Control, WHO Regional Office for Europe. HIV/AIDS surveillance in Europe 2014. This publication follows the ECDC terminological practice, which reflects the European Union Interinstitutional Style Guide with regard to names and designations of countries. The names and designations of countries used in this publication should not be understood as an endorsement by WHO of the terminology used in this publication. ECDC amended the maps supplied by the WHO Regional Office for Europe for this publication. The designations employed and the presentation of this material do not imply the expression of any opinion whatsoever on the part of the Secretariat of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers and boundaries. The WHO Regional Office for Europe is responsible for the accuracy of the translation of the Russian summary. © World Health Organization, 2015. Keywords ACQUIRED IMMUNODEFICIENCY SYNDROME – EPIDEMIOLOGY AIDS AND ITS CONTROL DISEASE OUTBREAKS – STATISTICS HIV INFECTIONS – EPIDEMIOLOGY POPULATION SURVEILLANCE Errata: The legend of Map 7 was corrected on 4 December 2015. On 9 February 2016, the following changes were made: On page 15, paragraph 2, the words ‘decrease may even out’ replaced the words ‘increase is likely to be reinforced’; on page 27, some repeated text was deleted; on page 101, the column heading was corrected to ‘Coverage’. Cover picture © Stockxpert ISBN 978-92-9193-731-8 ISSN 2363-3085 doi 10.2900/29461 Catalogue number TQ-AL-15-001-EN-N © European Centre for Disease Prevention and Control, 2015. Reproduction is authorised, provided the source is acknowledged. ii SURVEILLANCE REPORT The report was coordinated by Anastasia Pharris (ECDC) and Annemarie Stengaard (WHO Regional Office for Europe). Report review and production support were provided by Andrew J. Amato-Gauci, Julien Beauté, Mike Catchpole, Denis Coulombier, Martin Donoghoe, Nedret Emiroglu, Shahin Khasiyev, Valentina Lazdina, Marc Rondy, Chantal Quinten and Phillip Zucs. The European Centre for Disease Prevention and Control (ECDC) and the WHO Regional Office for Europe would like to thank the nominated national operational contact points for HIV/AIDS surveillance from EU/EEA Member States and the national HIV/AIDS surveillance focal points from other countries of the WHO European Region for providing data and valuable comments on this report: Albania: Marjeta Dervishi; Andorra: Jennifer Fernández Garcia; Armenia: Trdat Grigoryan; Austria: Daniela Schmid; Azerbaijan: Farhad Singatulov, Shahin Khasiyev; Belarus: Svetlana Sergeenko, Elena Fisenko; Belgium: Andre Sasse, Dominique Van Beckhoven; Bosnia and Herzegovina: Zlatko Cardaklija, Stela Stojisavljevic; Bulgaria: Tonka Varleva; Croatia: Tatjana Nemeth Blazic; Cyprus: Linos Hadjihannas, Maria Koliou; Czech Republic: Marek Maly; Denmark: Susan Cowan; Estonia: Kristi Rüütel; Finland: Kirsi Liitsola, Mika Salminen; the former Yugoslav Republic of Macedonia: Zarko Karadzovski, Zvonko Milenkovic; France: Françoise Cazein, Josiane Pillonel, Florence Lot; Georgia: Otar Chokoshvili, Maia Tsereteli; Germany: Barbara Gunsenheimer-Bartmeyer; Greece: Georgios Nikolopoulos, Dimitra Paraskeva; Hungary: Maria Dudas; Iceland: Haraldur Briem, Gudrun Sigmundsdottir; Ireland: Derval Igoe, Kate O’Donnell, Darina O’Flanagan; Israel: Daniel Chemtob; Italy: Barbara Suligoi; Kazakhstan: Lolita Ganina, Gulnar Temirkhanov; Kyrgyzstan: Aigul Solpueva; Latvia: Šarlote Konova; Liechtenstein: Sabine Erne; Lithuania: Irma Čaplinskienė; Luxembourg: Jean-Claude Schmit; Malta: Jackie Maistre Melillo, Tanya Melillo; Moldova: Stepan Gheorghita, Lucia Pirtina; Monaco: Dominique De Furst; Montenegro: Boban Mugosa, Alma Cicic; Netherlands: Eline Op de Coul; Norway: Hans Blystad; Poland: Magdalena Rosinska; Portugal: Antonio Diniz; Romania: Mariana Mardarescu; Russia: Natalia Ladnaia; San Marino: Andrea Gualtieri, Mauro Fiorini; Serbia: Danijela Simic; Slovakia: Peter Truska; Slovenia: Irena Klavs; Spain: Mercedes Diez; Sweden: Maria Axelsson; Switzerland: Martin Gebhardt; Tajikistan: Zukhra Nurlaminova; Turkey: Ekin Cubukci; Ukraine: Ihor Kuzin, Violetta Martsynovska; United Kingdom: Valerie Delpech; Uzbekistan: Vokhid Nurmatov. SURVEILLANCE REPORT HIV/AIDS surveillance in Europe 2014 Contents Abbreviations ............................................................................................................................................................................................................................................ vii Overview of HIV and AIDS in Europe ........................................................................................................................................................................ viii European Union and European Economic Area ................................................................................................................................................................. viii WHO European Region .............................................................................................................................................................................................................................x Conclusions .................................................................................................................................................................................................................................................. xii Обзор эпидемиологической ситуации по ВИЧ/СПИДу в Европе ............................................................................... xiv Европейский союз и Европейская экономическая зона ...................................................................................................................................... xv Европейский регион ВОЗ ............................................................................................................................................................................................................. x vii Выводы ..........................................................................................................................................................................................................................................................xix 1 HIV and AIDS in the European Union and European Economic Area ............................................................................ 1 1.1 HIV diagnoses ....................................................................................................................................................................................................................................... 1 1.2 Trends in HIV diagnoses ............................................................................................................................................................................................................... 2 1.3 AIDS cases, morbidity and mortality ................................................................................................................................................................................... 6 1.4 Conclusions ........................................................................................................................................................................................................................................... 8 2 HIV and AIDS in the WHO European Region ............................................................................................................................................... 11 2.1 HIV and AIDS diagnoses in the WHO European Region ........................................................................................................................................ 11 2.2 HIV and AIDS diagnoses in the East .................................................................................................................................................................................. 15 2.3 HIV and AIDS diagnoses in the Centre ............................................................................................................................................................................. 21 2.4 HIV and AIDS diagnoses in the West ................................................................................................................................................................................ 23 2.5 Number of HIV tests performed ............................................................................................................................................................................................24 2.6 Conclusions ......................................................................................................................................................................................................................................... 25 Tables Table A: Characteristics of new HIV diagnoses reported in the WHO European Region, the EU/EEA, and West, Centre and East of the WHO European Region, 2014 ............................................................................................................................................................................................................................viii Table 1: New HIV diagnoses and rates per 100 000 population, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region ..................................................................................................................................................................... 32 Table 1a: New HIV diagnoses and rates per 100 000 population, by country and year of statistics (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region ..................................................................................................................................................................... 34 Table 2: New HIV diagnoses in males and rates per 100 000 population, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region .................................................................................................................................................. 36 Table 3: New HIV diagnoses in females and rates per 100 000 population, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region ..................................................................................................................................................38 Table 4: New HIV diagnoses in men infected through sex with men, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region .................................................................................................................................................. 40 Table 5: New HIV diagnoses in people infected through injecting drug use, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region .......................................................................................... 41 Table 6: New HIV diagnoses in people infected through heterosexual contact, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region ........................................................................................... 42 Table 7: New HIV diagnoses in people infected through mother-to-child transmission, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region ............................................................................................................................ 43 Table 8: New HIV diagnoses, by sex, transmission mode and year of diagnosis (2005–2014) and cumulative totals .................................................... 44 iii HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 8a: EU/EEA and non-EU/EEA countries .......................................................................................................................................................................................... 44 Table 8b: West, Centre and East of the WHO European Region ........................................................................................................................................................ 46 Table 9: New HIV diagnoses, by sex, age and year of diagnosis (2005–2014) and cumulative totals .................................................................................. 48 Table 9a: EU/EEA and non-EU/EEA countries .......................................................................................................................................................................................... 48 Table 9b: West, Centre and East of the WHO European Region ........................................................................................................................................................ 50 Table 10: HIV diagnoses in people infected through heterosexual contact, by country and transmission subcategory, cases diagnosed in 2014, in EU/EEA and other countries of the WHO European Region ............................................................................................................................................... 53 Table 11: HIV diagnoses, by country of report and region of origin, cases diagnosed in 2014, in EU/EEA and other countries of the WHO European Region .................................................................................................................................................................................................................................................... 54 Table 12: HIV diagnoses, by geographical area, transmission mode and country or subcontinent of origin, cases reported in 2014 ...................... 56 Table 12a: EU/EEA and non-EU/EEA countries ......................................................................................................................................................................................... 56 Table 12b: West, Centre, East of the WHO European Region .............................................................................................................................................................. 56 Table 13: New HIV diagnoses, by country of report and probable region of infection, in 2014, in EU/EEA and other countries of the WHO European Region .................................................................................................................................................................................................................................................... 58 Table 14: Percentage of new HIV diagnoses (2014) among persons >14 years reported with information about CD4 cell count, by CD4 cell count level (<200 and <350 cells per mm3 blood) and by transmission mode in cases with CD4 <350, in EU/EEA and other countries of the WHO European Region ............................................................................................................................................................................................................................ 61 Table 15: AIDS diagnoses and rates per 100 000 population, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/ EEA and other countries of the WHO European Region............................................................................................................................................................................ 62 Table 16: AIDS diagnoses in males and rates per 100 000 population, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region ................................................................................................................................................. 64 Table 17: AIDS diagnoses in females and rates per 100 000 population, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region ................................................................................................................................................. 66 Table 18: AIDS diagnoses in men infected through sex with men, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region ............................................................................................................................................................... 68 Table 19: AIDS diagnoses in people infected through injecting drug use, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region ................................................................................................................................................. 69 Table 20: AIDS diagnoses in people infected through heterosexual contact, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region ......................................................................................... 70 Table 21: AIDS diagnoses in people infected through mother-to-child transmission, by country and year of diagnosis (2005–2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region ........................................................................................................................... 71 Table 22: AIDS diagnoses, by sex, transmission mode and year of diagnosis (2005–2014) and cumulative totals ......................................................... 72 72 74 Table 23: AIDS diagnoses, by sex, age and year of diagnosis (2005–2014) and cumulative totals ....................................................................................... 76 Table 23a: EU/EEA and non-EU/EEA countries ........................................................................................................................................................................................ 76 Table 23b: West, Centre, East of the WHO European Region ............................................................................................................................................................ 78 Table 24: The most common AIDS-indicative diseases diagnosed in 2014, ordered by frequency ........................................................................................ 80 Table 24a: EU/EEA and non-EU/EEA countries ........................................................................................................................................................................................ 80 Table 24b: West, Centre, East of the WHO European Region .............................................................................................................................................................80 Table22a: EU/EEA and non-EU/EEA countries ......................................................................................................................................................................................... Table 22b: West, Centre, East of the WHO European Region ............................................................................................................................................................. Table 25: Deaths among people diagnosed with HIV and/or AIDS, by country and year of death (2005–2014) and cumulative totals in EU/EEA and other countries of the WHO European Region ..................................................................................................................................................................... 81 Table 26: Deaths among AIDS cases, by transmission mode and year of death (2005–2014) and cumulative totals ...................................................... 82 Table 26a: EU/EEA and non-EU/EEA countries ........................................................................................................................................................................................ 82 Table 26b: West, Centre, East of the WHO European Region ............................................................................................................................................................. 84 Table 27: Number of HIV tests performed, excluding unlinked anonymous testing and testing of blood donations, by country and year (2005–2014) and number of tests per 1 000 population in 2014, in EU/EEA and other countries of the WHO European Region ................................. 86 Figures Figure A: Rate of new HIV diagnoses per 100 000 population, by year of diagnosis and adjusted for reporting delay, in the EU/EEA and the WHO European Region, 1984-2014 ........................................................................................................................................................................................................... ix Figure B: Cumulative number of new HIV diagnoses in the EU/EEA and other countries of the WHO European Region, 1984-2014 .............................. x Figure C: New HIV diagnoses among non-migrants, European migrants, other migrants, adjusted for reporting delay, WHO European Region, 2005-2014 ..................................................................................................................................................................................................................................................xi Figure 1.1: Male-to-female ratio in new HIV diagnoses, by country, EU/EEA, 2014 ......................................................................................................................... 2 Figure 1.2: Age- and gender-specific rates of new HIV diagnoses per 100 000 population, EU/EEA, 2014 ............................................................................ 3 Figure 1.3: Number of new HIV diagnoses by age group and transmission mode, EU/EEA, 2014 ............................................................................................... 3 Figure 1.4: Percentage of new HIV diagnoses in people between 15 and 24 years old, by country, EU/EEA, 2014 ............................................................. 4 iv SURVEILLANCE REPORT HIV/AIDS surveillance in Europe 2014 Figure 1.5: Percentage of new HIV diagnoses with known mode of transmission, by transmission route and country, EU/EEA, 2014 ............................................................................................................................................................................................................................................................. 4 Figure 1.6: Percentage of new HIV diagnoses among migrants out of all reported cases with known information on region of origin, by country of report, EU/EEA, 2014 ......................................................................................................................................................................................................................... 5 Figure 1.7: New HIV diagnoses, by CD4 cell count per mm3 at diagnosis and transmission mode, EU/EEA, 2014 ................................................................ 5 Figure 1.8: New HIV diagnoses, by CD4 cell count per mm3 at diagnosis and region of origin of the case diagnosed, EU/EEA, 2014 ............................................................................................................................................................................................................................................................. 6 Figure 1.9: New HIV diagnoses, by transmission mode and year of diagnosis, adjusted for reporting delay, EU/EEA, 2005-2014 ............................... 7 Figure 1.10: New HIV diagnoses, by transmission and migration status, EU/EEA, 2005-2014 .................................................................................................... 7 Figure 1.11: Median CD4 cell count per mm3 at HIV diagnosis, by transmission group, EU/EEA, 2005-2014 ........................................................................ 8 Figure 1.12: AIDS diagnoses, by transmission mode, EU/EEA, 2005-2014 (logarithmic scale) ................................................................................................... 8 Figure 1.13: Percentage of AIDS diagnoses made in 2014 which occurred within 90 days of HIV diagnosis, EU/EEA, 2014 ............................................ 9 Figure 2.1: New HIV diagnoses, by CD4 cell count per mm3 at diagnosis and transmission mode, WHO European Region, 2014 ................................12 Figure 2.2a: Rates of new HIV diagnoses, by year of diagnosis, WHO European Region, 2005-2014 (including Russia) .................................................12 Figure 2.2b: Rates of new HIV diagnoses, by year of diagnosis, WHO European Region, 2005-2014 (excluding Russia) ................................................ 12 Figure 2.3: New HIV diagnoses, by transmission mode and year of diagnosis, WHO European Region, 2005-2014 ..........................................................1 4 Figure 2.4: Rates of new AIDS diagnoses, by geographical area and year of diagnosis, WHO European Region, 2005-2014 ........................................1 4 Figure 2.5: Male-to-female ratio in all new HIV diagnoses and new diagnoses with heterosexual transmission, by country, East, 2014 ................15 Figure 2.6: New HIV diagnoses, by age group and transmission mode, East, 2014 ......................................................................................................................16 Figure 2.7: New HIV diagnoses by country and transmission mode, East, 2014 ............................................................................................................................. 17 Figure 2.8: New HIV diagnoses, by CD4 cell count per mm3 at diagnosis and transmission mode, East, 2014 ...................................................................18 Figure 2.9: New HIV diagnoses, by transmission mode and year of diagnosis, East, 2005-2014 .............................................................................................19 Figure 2.10: New AIDS diagnoses, by transmission mode and year of diagnosis, East, 2005-2014 ...................................................................................... 20 Figure 2.11: Distribution of the three most common AIDS-defining illnesses per transmission mode, East, 2014 ..........................................................20 Figure 2.12: Male-to-female ratio in new HIV diagnoses, by country, Centre, 2014 .....................................................................................................................21 Figure 2.13: New HIV diagnoses by country and transmission mode, Centre, 2014 .................................................................................................................... 23 Figure 2.14: New HIV diagnoses, by CD4 cell count per mm3 category at diagnosis and transmission mode, Centre, 2014 ........................................24 Figure 2.15: New HIV diagnoses, by transmission mode and year of diagnosis, Centre, 2005-2014 ..................................................................................... 25 Figure 2.16: New AIDS diagnoses, by transmission mode and year of diagnosis, Centre, 2005-2014 .................................................................................. 25 Figure 2.17: Distribution of the three most common AIDS-defining illnesses per transmission mode, Centre, 2014 ..................................................... 26 Figure 2.18: New HIV diagnoses, by transmission mode and year of diagnosis, West, 2005-2014 ........................................................................................26 Figure 2.19: New AIDS diagnoses, by transmission mode and year of diagnosis, West, 2005-2014 ..................................................................................... 26 Figure 2.20: Distribution of the three most common AIDS-defining illnesses per transmission mode, West, 2014 ....................................................... 27 Maps .................................................................................................................................................................................................................................................................... 87 Map 1: New HIV diagnoses per 100 000 population, 2014 .....................................................................................................................................................................88 Map 2: New HIV diagnoses in men per 100 000 male population, 2014 ...........................................................................................................................................88 Map 3: New HIV diagnoses in women per 100 000 female population, 2014 ..................................................................................................................................89 Map 4: New HIV diagnoses in men who have sex with men per 100 000 male population, 2014 ............................................................................................89 Map 5: New HIV diagnoses acquired through injecting drug use per 100 000 population, 2014 ............................................................................................ 90 Map 6: New HIV diagnoses acquired through heterosexual transmission per 100 000 population, 2014 ........................................................................... 90 Map 7: Percentage of adult (>14 years) HIV diagnoses with CD4 <350 cells/mm3 at diagnosis, 2014 ..................................................................................... 91 Map 8: AIDS diagnoses reported per 100 000 population, 2014 ......................................................................................................................................................... 91 Annexes .......................................................................................................................................................................................................................................................... 93 Annex 1: Framework for data collection, validation and presentation ............................................................................................................................................... 95 Annex 2: List of variables* for 2014 HIV/AIDS data collection .............................................................................................................................................................. 99 Annex 3: Completeness of variables for data reported in 2013 and 2014 ...................................................................................................................................... 100 Annex 4a: HIV surveillance system overview: data source information .......................................................................................................................................... 101 Annex 4b: AIDS surveillance system overview: data source information ....................................................................................................................................... 102 Annex 5: Country-specific comments regarding national HIV and AIDS reporting ...................................................................................................................... 103 Annex 6: HIV diagnoses and rate per 100 000 population, adjusted for reporting delay and adjustment coefficients, EU/EEA countries, 2011–2014 ............................................................................................................................................................................................................................................................. 104 Annex 7: HIV/AIDS surveillance in Europe: participating countries and national institutions ............................................................................................... 105 v SURVEILLANCE REPORT HIV/AIDS surveillance in Europe 2014 Abbreviations AIDS Acquired immunodeficiency syndrome ART Antiretroviral therapy ECDC European Centre for Disease Prevention and Control EEA European Economic Area EU European Union HIV Human immunodeficiency virus ICJ International Court of Justice MSM Men who have sex with men TESSy The European Surveillance System UN United Nations UNSCR United Nations Security Council Resolution WHO World Health Organization vii HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Overview of HIV and AIDS in Europe Although HIV is preventable through effective public health measures, significant HIV transmission continues in Europe. In 2014, 142 197 people were newly diagnosed with HIV in 50 of the 53 countries of the WHO European Regioni. Of those, 56 945 were officially reported to the joint ECDC/WHO Regional Office for Europe surveillance system by 49 countries, including 29 992 from the European Union and European Economic Area (EU/ EEA), while information about 85 252 new diagnoses in 2014 was published by the Russian Federal Scientific and Methodological Centre for Prevention and Control of AIDS [1]. In the 50 countries, the rate of newly diagnosed infections was 16.4 per 100 000 population (Table A). The cited data source from Russia allowed inclusion of Russian data within regional HIV annual and cumulative totals and rates, quotation of country-specific annual and cumulative HIV totals and rates and data by transmission mode, and inclusion of cumulative total AIDS diagnoses into regional totals. All other regional HIV figures and all 2014 AIDS data presented in this report are based on data from the 49 countries reporting to ECDC/ WHO. Among the 49 officially reporting countriesii the rate was 7.9 per 100 000 population and 5.9 per 100 000 for the EU/EEA (Figure A). As in recent years, rates and overall numbers of people diagnosed with HIV were highest in the East of the Region and lowest in the Centreiii (Table A). The main transmission mode varied by geographical area, illustrating the diversity in the epidemiology of HIV in Europe; sexual transmission between men was the most common mode in the EU/EEA and heterosexual transmission was the main transmission mode in the East of the Region. 31% of new HIV diagnoses in the WHO European Region were among people originating from outside of the reporting country, including 22% originating from outside the WHO European Region and 9% originating from a European country other than the country of report. Between 2005 and 2014, new HIV diagnoses among non-natives decreased by 28% overall. Examining this trend by region of origin reveals that new diagnoses in migrants originating from outside the WHO European Region decreased by 41% but increased by 48% among European migrants (i.e. people originating from a European country other than the country of report) (Figure C, Table 11). In 2014, 16 037 people were diagnosed with AIDS in 47 countriesiv of the WHO European Region and the rate of new diagnoses for the WHO European Region was 2.3 per 100 000 population and 0.8 per 100 000 for the EU/EEA. Although the number of AIDS cases continued its steady decline in the West and the EU/EEA, it has more than doubled in the East during the last decade. European Union and European Economic Area i No data available from Bosnia and Herzegovina, Turkmenistan or Uzbekistan. One case from Liechtenstein is included in the total number of newly diagnosed HIV infections presented in this report but, since Liechtenstein is not a Member State of the WHO European Region, data for Liechtenstein are not included in the totals for the West, Centre and East of the WHO European Region. In 2014, 29 992 people were diagnosed with HIV in the 31 countries of the EU/EEA, with a rate of 5.9 per 100 000 population (6.4 per 100 000 when adjusted for reporting delay) (Table 1). Countries with the highest rates ii No data from Bosnia and Herzegovina, Russia, Turkmenistan or Uzbekistan. iii The grouping of countries into the West (23 countries), Centre (15 countries) and East (15 countries) of the WHO European Region is based on epidemiological considerations and follows the division of countries used in previous reports published by EuroHIV since 1984: See Annex 1, Figure A1 for details. iv No data available from Bosnia and Herzegovina, Russia, San Marino, Sweden, Turkmenistan or Uzbekistan. Table A: Characteristics of new HIV diagnoses reported in the WHO European Region, the EU/EEA, and West, Centre and East of the WHO European Region, 2014 Reporting countries/Number of countries Number of new HIV diagnoses Rate per 100 000 population Percentage age 15-24 years Male-to-female ratio Transmission mode Men who have sex with men Heterosexual Injecting drug use Mother to child transmission Unknown WHO European Region 49/53 (50/53) 56 972 (142 197) 7.9 (16.4) 10.2% 2.2 West 23/23 27 325 6.4 10.6% 3.3 Centre 14/15 4950 2.6 14.9% 4.4 East 12/15 (13/15) 24 669 (109 930) 22 (43.2) 8.7% 1.4 EU/EEA 31/31 29 992 5.9 11.1% 3.3 24.4% 46.8% 14.0% 1.0% 13.5% 43.9% 33.7% 3.1% 0.8% 18.1% 28.0% 24.3% 5.4% 1.0% 40.9% 2.2% 66.0% 27.8% 1.2% 2.9% 42.3% 32.8% 4.1% 0.8% 19.7% No data received from Bosnia and Herzegovina, Russia, Turkmenistan, Uzbekistan. All data presented were reported to ECDC/WHO through the European Surveillance System (TESSy), except for data for Russia which were obtained through the Russian Federal Scientific and Methodological Center for Prevention and Control of AIDS [1] . Russian data are included in the numbers in parentheses for the European Region and the East. viii HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT of 6.7 per 100 000 in 2005 (29 129 cases) compared with 6.4 per 100 000 (32 605 cases) in 2014 when adjusted for reporting delay (Table 1, Annex 6). Trends by transmission mode show that the number of HIV diagnoses among MSM in countries with consistent reporting has continued to increase in the EU/EEA as a whole (Table 8; Figure 1.9), with sustained increases over the last decade reported in all but six EU/EEA countries (Table 4). Cases attributed to MSM increased over this period both among men born in the country of report and those born outside it (Figure 1.10). The numbers of HIV diagnoses due to heterosexual transmission decreased by 40% during the last decade, with sharper decreases seen among people born outside of the country of report, particularly those coming from countries with generalised HIV epidemics (Table 8, Figure 1.10). The number of people who acquired HIV through injecting drug use has decreased by 44% over the same period (Table 8). An overall increase among cases attributed to injecting drug use was observed in 2011 and 2012 due to localised outbreaks in Greece and Romania (Table 5), but reported cases in 2013 and 2014 in these countries show a downward trend. Mother-to-child transmission and transmission through nosocomial infection or blood transfusion have decreased steadily between 2005 and 2014 and remain at less than 1% of cases diagnosed (Table 8). of new HIV diagnoses reported in 2014 were Estonia (22.1; 291 cases), Latvia (17.3; 347 cases) and Luxembourg (12.6; 69 cases). The lowest rates were reported by Slovakia (1.6; 86 cases), Croatia (2.2; 92 cases) and the Czech Republic (2.2; 232 cases). The rate of new HIV diagnoses was higher among men (9.2 per 100 000 population; Table 2), than women (2.6 per 100 000 population; Table 3). The overall male-tofemale ratio was 3.3 (Table A). This ratio was highest in Slovenia (15.0), Hungary (10.6), Croatia (9.2), the Czech Republic (9.1) and Malta (9.0) (Figure 1.1). The predominant mode of transmission in these countries was sex between men (Figure 1.5). The highest crude age-specific rate of HIV diagnoses was observed among 25-to-29-year-olds (14.6 per 100 000 population) with the rates for men and women peaking in this age group at 22.7 and 6.2 per 100 000, respectively (Figure 1.2). Similar to recent years, the highest proportion of HIV diagnoses was reported to be in men who have sex with men (MSM) (42%), with heterosexual contact the second most common transmission mode (33%).Transmission due to injecting drug use accounted for 4% of HIV diagnoses, and for nearly 20% of new HIV diagnoses the transmission mode was not reported or was reported to be unknown (Table A). Of the total number of people diagnosed, more than one third (37%) originated from outside of the reporting country (Figure 1.6), although this varied widely from 82% in Iceland and 78% in Sweden to less than 5% of cases in Croatia, Estonia, Hungary, Latvia, Poland, Romania and Slovakia. In 2014, information on CD4 cell count at the time of HIV diagnosis was provided by 22 countries (Table 14) for 18 411 (61%) people (>14 years old) diagnosed with HIV (Table 14). Nearly half (47%) of all people diagnosed who had CD4 cell count information available had a reported CD4 cell count of less than 350 cells per mm3 at diagnosis, including 27% of cases with advanced HIV infection (CD4 <200 cells/mm3). Among all those diagnosed for whom CD4 cell count information was available, 20% had a CD4 cell count of between 350 and Despite continuing prevention efforts and resources allocated by countries in the EU/EEA, there has been only a minimal decline in the number of HIV diagnoses per 100 000 population over the last decade, with a rate Figure A: Rate of new HIV diagnoses per 100 000 population, by year of diagnosis and adjusted for reporting delay, in the EU/EEA and the WHO European Region*, 1984-2014 9 WHO European Region Cases per 100 000 population 8 EU/EEA 7 6 5 4 3 2 1 0 1984 1986 1988 1990 1992 1994 1996 1998 2000 2002 2004 2006 2008 2010 2012 2014 Year of diagnosis Countries reporting * 15 25 27 36 36 39 42 42 42 42 44 43 45 48 48 47 47 49 46 50 52 52 52 51 52 52 53 51 51 49 49 Rates may increase in the coming years due to reporting delays Data from Russia are not included ix HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT 500 cells per mm3 and 33% had a CD4 cell count of 500 or more per mm3 (Figure 1.7). When analysing CD4 cell count by transmission mode, the highest proportion of people presenting at a later stage of HIV infection (CD4 <350 cells/mm3) was observed among people who inject drugs (61%) (Figure 1.8). The lowest proportion with a CD4 count lower than 350 cells per mm3 was observed among people who acquired HIV through sex between men (37%). The proportion of cases diagnosed at or below 350 CD4 cells per mm3 increased with age, and 61% of persons aged 50 or older were diagnosed with HIV at or below 350 cells per mm3. Higher proportions of persons from sub-Saharan Africa (57%) and south and south-east Asia (57%) had CD4 counts of less than 350 cells per mm3 at diagnosis than non-migrants (46%) and other migrant groups (Figure 1.8). In 2014, 4 020 people were diagnosed with AIDS in 31 EU/EEA countries, which is a rate of 0.8 cases per 100 000 population (Table 15). The highest rates were reported by Latvia (8.5) and Portugal (2.4). In the EU/ EEA, the number of AIDS cases has consistently declined since the mid-1990s. Among the 20 EU/EEA countries where it was possible to fully link HIV and AIDS cases, 69% of AIDS diagnoses occurred at the same time as, or within 90 days of, the HIV diagnosis. This ranged from 100% of AIDS cases reported (Cyprus, Denmark, Norway and Slovenia) to around 47% of new AIDS diagnoses in Austria and Belgium and 26% in Latvia (Figure 1.13). WHO European Region With 142 197 people newly diagnosed with HIV in the WHO European Region in 2014 – the highest annual number since reporting started in the 1980s – the cumulative number of diagnosed infections in the European Region increased to 1 840 136. This number includes 995 175 diagnoses officially reported to the joint ECDC and the WHO Regional Office for Europe surveillance system (Figure B) and 907 607 infections diagnosed in Russiai i Minus the 62 581 cases officially reported to ECDC/WHO by Russia in 2010. [1]. Of the 142 197 people newly diagnosed with HIV in 2014 in the 50 countriesii, 77% were diagnosed in the East (109 921), 19% in the West (27 325) and 3% in the Centre of the Region (4 950) (Table A). The rate was also highest in the East (43.2 per 100 000 population), considerably higher than in the West (6.4 per 100 000) and the Centre (2.6 per 100 000) (Table A). Across the 49 countries reporting to ECDC/WHOiii, 43% of people newly diagnosed (24 669) were reported in the East with a rate of 22.0 per 100 000, 48% in the West and 9% in the Centre. For men, the Regional rate was 11.1 per 100 000 population (Table 2) and for women, 4.7 per 100 000 population (Table 3). Rates of newly diagnosed HIV infections for 2014 varied widely between countries in the WHO European Region. In Russia the rate was 58.4 per 100 000 population, the highest in the Region [1]. Among countries reporting to ECDC/WHO, rates were highest in Ukraine (36.9) iv, Estonia (22.1), Moldova (20.4), Belarus (19.1), Latvia (17.3), Kazakhstan (13.5), Georgia (13.3), Luxembourg (12.6), Tajikistan (11.9) and Kyrgyzstan (11.0) and lowest in the former Yugoslav Republic of Macedonia (1.4), Serbia (1.4), Slovakia (1.6), Croatia (2.2), the Czech Republic (2.2), Turkey v (2.3) and Slovenia (2.4) (Table 1). In the reporting countries the majority of people newly diagnosed (36%) were in the age group 30–39 years, while 10% were young people aged 15–24 years. The male-to-female ratio was 2.2, lowest in the East (1.4.), higher in the West (3.3) and highest in the Centre (4.4) (Table A). People had been infected most commonly through heterosexual contact (47%), including 13% who originated from countries with generalised epidemics, ii No data available from Bosnia and Herzegovina, Turkmenistan or Uzbekistan. iii No data from Bosnia and Herzegovina, Russia, Turkmenistan or Uzbekistan. iv Excluding data from Crimea and Sevastopol City. v HIV data for Turkey do not include people diagnosed with AIDS at the time of HIV diagnosis and are therefore not directly comparable with data for other countries. Figure B: Cumulative number of new HIV diagnoses in the EU/EEA and other countries of the WHO European Region*, 1984-2014 1000000 EU/EEA Other countries of the WHO European Region Number of cases 800000 600000 400000 200000 0 1985 1990 1995 2000 Year of diagnosis * x Data from Russia not included 2005 2010 2014 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Figure C: New HIV diagnoses among non-migrants, European migrants, other migrants, adjusted for reporting delay, WHO European Region, 2005-2014 20000 Non-migrants (people originating from the reporting country) Other migrants (people originating from outside the WHO European Region) Number of cases 15000 European migrants (people originating from a European country other than the reporting country) 10000 5000 0 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Year of diagnosis Data from Bulgaria, Estonia, Italy, Russia, Spain, Ukraine, Uzbekistan and Turkmenistan excluded due to inconsistent reporting on incomplete reporting on country of birth and region of origin during the period while 24% were infected through sex between men, 14% through injecting drug use and 1% through motherto-child transmission. Information about transmission mode was missing for 13% of new diagnoses. In the East, heterosexual contact and injecting drug use were the main modes of HIV transmission (66% and 28% of new diagnoses, respectively) while reported transmission through sex between men remained very low (2% of cases). In Russia, of people newly diagnosed with a known mode of HIV transmissioni (which amounts to about half of cases [2]), 57% were infected through injecting drug use, 40% through heterosexual transmission, 1% through sex between men and 0.1% through mother-to-child transmission [1]). The large number of new diagnoses in Russia of people infected through injecting drug use increases the significance of that mode of transmission in the East of the Region. In the Centre, sex between men (28%) and heterosexual contact (24%) were the main transmission modes, with sex between men predominating in 10 of the 14 countries, while information about transmission mode was lacking for 41% of new diagnoses. In the West, sex between men remained the main transmission mode (44% of new diagnoses), followed by heterosexual transmission (34% of new diagnoses). Overall, between 2005 and 2014, the rate of newly diagnosed HIV infections increased by 59% from 10.3 per 100 000 population (80 652 cases) to 16.4 per 100 000 population (142 197 cases) for 50 countries (Russia included [1]). The increase is mainly driven by an upward trend in the East where the rate continued to rise with a 115% increase from 20.1 per 100 000 in 2005 (51 058 cases) to 43.2 per 100 000 in 2014 (109 921 cases). In the 49 countriesii that provided data to ECDC and WHO, the rate for the Region increased by 11%, from 7.1 in 2005 (45 251 cases) to 7.9 in 2014 (56 945 cases); and in the East the rate increased by 59%, from 14.1 in 2005 (15 657 cases) to 22.3 in 2014 (24 669 cases). In the Centre, the rate increased by 117%, the largest relative increase of the three geographical areas, from 1.2 (2 165 cases) to 2.6 (4 950 cases) whereas in the West the rate decreased by 20%, from 8.0 (27 429 cases) in 2005 to 6.4 (27 325) in 2014. Trends by transmission mode in 44 countries with consistent dataiii showed increases in the number of people infected through heterosexual contact (28% increase) and sex between men (28% increase), whereas infections due to injecting drug use decreased by 22%. In the East, sexual transmission increased (by 171% for heterosexual transmission and 10-fold for transmission through sex between men), while transmission through injecting drug decreased by 17% in comparison with 2005. At the same time, the number of women newly diagnosed increased by 74%, and the number of men newly diagnosed increased by 49%. In the Centre, people infected through sex between men more than tripled, heterosexual transmission increased by 26% and transmission through injecting drug use increased sixfold due to an outbreak in Romania that started in 2011, peaked in 2012 and has since slowed. In the West, transmission through sex between men increased by 15% whereas heterosexual transmission decreased by 44%, with an even steeper decline among people originating from generalised epidemic countries, and transmission through injecting drug use decreased by 60%. ii No data from Bosnia and Herzegovina, Russia, Turkmenistan or Uzbekistan. i This analysis approach is different from the rest of the report where cases with unknown transmission mode are shown separately and included in the denominator for percentage calculations. The percentages for Russia are therefore not directly comparable with those of other countries or groups of countries in this report. iii Data from Estonia, Poland and Turkey were excluded because more than 50% of their data on transmission mode was missing; data from Spain and Italy were excluded because coverage of the national surveillance system increased over this time period; and data from Bosnia and Herzegovina, Russia, Turkmenistan and Uzbekistan were not reported. xi HIV/AIDS surveillance in Europe 2014 Close to half (48%) of people (>14 years old) newly diagnosed for whom information about CD4 cell count at the time of HIV diagnoses was available, were late presenters with CD4 cell counts below 350 cells per mm3, including 28% with advanced HIV infection (CD4 <200 cells/mm3). 20% had a CD4 cell count of between 350 and 500 cells per mm3 and 32% had a CD4 cell count of 500 or more cells per mm3. The percentage of late presenters varied across transmission categories and was highest for people infected through injecting drug use (64%), lower for people infected through heterosexual contact (56%) and lowest for men infected through sex with men (37%). The percentage of people diagnosed at or below 350 CD4 cells per mm3 increased with age, and 61% of persons aged 50 or older were diagnosed with HIV with CD4 cell counts at or below 350 cells per mm3. In 2014, 16 037 people were newly diagnosed with AIDS in 47 countries of the WHO European Regioni with a rate of 2.3 per 100 000 population. 74% of people (11 890) were diagnosed in the East, 20% (3 214) in the West and 6% (932) in the Centre of the Region. The rate was also highest in the East (10.7 per 100 000 population), thirteen times higher than in the West (0.8 per 100 000) and 21 times higher than in the Centre (0.5 per 100 000). Between 2005 and 2014, the rate of new AIDS diagnoses decreased by 4% in the Region from 2.3 (14 294 cases) to 2.2 (16 037 cases). There was, however, great variation between the three geographical areas: a 143% increase in the East from 4.4 per 100 000 in 2005 (4 926 cases) to 10.7 (11 890 cases), a 25% rate increase in the Centre from 0.4 (751 cases) to 0.5 (932 cases) and a steady 69% decline in the West from 2.6 per 100 000 (8 617 cases) to 0.8 (3 214 cases). Conclusions HIV transmission remains of major concern in Europe, in particular in the eastern part of the WHO European Region. In 2014, more than 142 000 people were diagnosed with HIV, the highest number of newly diagnosed infections ever reported in one year. Of these, 77% were diagnosed in the East of the Region and 21% in the EU/ EEA. The most recent surveillance data indicate that, despite significant efforts dedicated to the prevention and control of HIV, the number of new HIV diagnoses has not declined substantially in the western part of the Region and the EU/EEA and has more than doubled over the last decade in the East. In the Centre, while remaining lower than in the East and West, the number of new diagnoses has also more than doubled over the last decade. While epidemic patterns and trends vary widely across European countries, there have been sustained increases in the number of infections among men who have sex with men in the western and central parts of the Region and among people infected heterosexually, notably women, in the eastern part of the Region. i No data available from Bosnia and Herzegovina, Russia, San Marino, Sweden, Turkmenistan or Uzbekistan. xii SURVEILLANCE REPORT Transmission through injecting drug use has continued to decrease but still accounted for more than a quarter of reported new diagnoses in the East. At the same time, new diagnoses among persons born outside the reporting country, particularly people originating from countries outside the European Region, are decreasing. In 2015, new WHO HIV treatment guidelines were issued recommending that antiretroviral therapy (ART) should be initiated in all people living with HIV, irrespective of CD4 count [3]. There is now evidence that early treatment is beneficial both to the health of the treated individual and in preventing onward HIV transmission [4, 5]. However, too many people throughout the European Region are diagnosed late (48%), with implications for greater risks for ill health, death and onward HIV transmission. The high and alarming increases in the number of AIDS cases in the East also suggest that late HIV diagnosis, delayed initiation of ART and low treatment coverage remain major challenges. To decrease the number of people who are diagnosed late, new strategies are required for the delivery of expanded targeted HIV testing services. New WHO consolidated guidance for HIV testing services [6] provides new recommendations that support HIV testing by trained lay providers (community-based HIV testing) in addition to provider-initiated testing; considers the potential of HIV self-testing to increase access to, and coverage of, HIV testing; and outlines focused and strategic approaches to HIV testing services that are needed to support the first of the three 90-90-90 targets (90% of people living with HIV know their HIV status) [7]. These services should focus on reaching the most affected population groups in the local epidemic context, be tailored to the specific needs of these groups and support timely linkage to HIV prevention, treatment and care. This will ensure earlier diagnoses and treatment initiation and result in improved treatment outcomes, reduced morbidity, mortality and HIV incidence in support of the second and third 90-90-90 targets (90% of diagnosed people living with HIV receive treatment and 90% of people on treatment achieve viral suppression). Interventions to control the epidemic should be based on evidence and adapted to the national and local epidemiology. From the comprehensive epidemiological data presented in this report, the following can be concluded: • For the countries in the EU/EEA and West, considering the persistent increase in cases diagnosed in MSM over the last decade, it would appear that current prevention and control interventions need to be scaled up and strengthened and should remain the priority cornerstone of the HIV response. Multi-component interventions, including the consideration of new strategies such as the inclusion of pre-exposure prophylaxis for HIV into the package of prevention interventions, could help to curb this increased trend [8, 9, 10]. The observed increases in HIV cases among people who inject drugs in a number of countries [2, 3] in recent years demonstrates the need to maintain or scale up harm reduction programmes. HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT • For the countries in the Centre, the epidemic remains at a low level but with a higher relative increase than in any other part of Europe. With the increase being driven by sexual transmission, mainly among MSM but also through heterosexual contact and with 4 in 5 new diagnoses being among men, the priority is to strengthen and target a mix of interventions to prevent, test and treat HIV in this relatively broad group. Efforts to reduce stigma and discrimination will be key to achieving this. • For the countries in the East, there is an urgent need to scale up bold evidence-based actions and deliver more effective, integrated services through health systems that better address the social determinants of health. Comprehensive coverage with effective prevention for people at risk of heterosexual transmission and people who inject drugs, effective targeted HIV testing, and access to counselling and integrated care should be provided to all in need. In couples where one partner is engaged in a high-risk behaviour (injecting drug use, purchased sex, bisexual relations or is working abroad for long periods of time) bolder prevention interventions should address the risk of heterosexual transmission, including through the use of pre-exposure prophylaxis where relevant and according to WHO recommendations [3, 11]. Evidencebased policies targeting key populations, particularly people who inject drugs, and including harm reduction programmes, need to remain central in the HIV response. Access to antiretroviral therapy needs to be scaled up to treat and prevent HIV transmission and reduce the growing number of AIDS cases. • Although HIV diagnoses among migrants have decreased considerably since 2005, 31% of diagnoses are among persons born abroad, including 22% originating from outside the WHO European Region. New diagnoses among all migrants decreased by 28% overall and by 41% in people originating from countries outside Europe since 2005. There is evidence that a significant proportion of migrants acquire HIV after migrating to the European Region [12, 13, 14]. It therefore remains crucial that countries ensure that HIV prevention, treatment and care are accessible to migrants. References 1 Federal Scientific and Methodological Center for Prevention and 1 Russian Federal Scientific and Methodological Center for Prevention and Control of AIDS. Information note ”Spravka” on HIV infection in the Russian Federation as of 31 December 2014. Moscow: Russian Federal Scientific and Methodological Center for Prevention and Control of AIDS; 2015. Available at: http://hivrussia.org/files/ spravkaHIV2014.pdf. 2 Hedrich D, Kalamara E, Sfetcu O, Pharris A, Noor A, Wiessing L, et al. Human immunodeficiency virus among people who inject drugs: Is risk increasing in Europe? Euro Surveill. 2013;18(48):pii=20648. Available online: http://www.eurosurveillance.org/ViewArticle. aspx?ArticleId=20648 3 World Health Organization. Guidelines on when to start antiretroviral therapy and on pre-exposure prophylaxis for HIV. Geneva: World Health Organization; 2015. http://apps.who.int/iris/bitstr eam/10665/186275/1/9789241509565_eng.pdf 4 INSIGHT START Study Group. Initiation of antiretrovial therapy in early asymptomatic HIV infection. N Engl J Med. 2015;373(9):795-807. 5 Cohen MS, Chen YQ, McCauley M, Gamble T, Hosseinipour MC, Kumarasamy N, et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med. 2011;365(6):493-505. 6 World Health Organization. Consolidated guidelines on HIV testing services. Geneva: World Health Organization; 2015. 7 UNAIDS. Ambitious treatment targets: Writing the final chapter of the AIDS epidemic. Geneva; 2014. Available at: h t t p://w w w. u n a i d s .o r g /s i te s/d e f a u l t /f i l e s/m e d i a _ a s s e t / JC2670_UNAIDS_Treatment_Targets_en.pdf 8 European Centre for Disease Prevention and Control. HIV and STI prevention among men who have sex with men. ECDC Guidance. Stockholm: ECDC; 2014. Available at: http://ecdc.europa.eu/en/ publications/Publications/hiv-sti-prevention-among-men-whohave-sex-with-men-guidance.pdf 9 World Health Organization. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection. Recommendations for a public health approach. Geneva: World Health Organization; 2013. 10 McCormack S, Dunn DT, Desai M, Dolling DI, Gafos M, Gilson R, et al. Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial. Lancet. 2015 Sep 9. pii: S0140-6736(15)00056-2 [Epub ahead of print]. 11 World Health Organization. Consolidated guidelines on HIV prevention, diagnosis, treatment and care for key populations. Geneva: World Health Organization; 2014. 12. Rice BD, Elford J, Yin Z, Delpech VC. A new method to assign country of HIV infection among heterosexuals born abroad and diagnosed with HIV. AIDS. 2012;26(15):1961-1966. 13. Fakoya I, Alvarez-del Arco D, Woode-Owusu M, Monge S, RiveroMontesdeoca Y, Delpech V, et al. A systematic review of postmigration acquisition of HIV among migrants from countries with generalised HIV epidemics living in Europe: implications for effectively managing HIV prevention programmes and policy. BMC Public Health. 2015; 15: 561. 14. Alvarez-del Arco D, Fakoya I, Monge S, Gennotte AF, Touloumi G, Zuure F, et al; aMASE. HIV Acquisition among migrants living in Europe: Results from aMASE (Advancing Migrant Access to Health Services in Europe). Paper presented at: European AIDS Clinical Society Conference. 15th European AIDS Conference; 2015 October 21-24; Barcelona, Spain. Finally, robust surveillance data are critical to monitor and inform the public health response to the European HIV epidemic in an accurate and timely fashion. The number of countries conducting enhanced HIV surveillance and reporting surveillance data at European level has gradually increased over time. For the first time in 2014, 33 countries submitted linked HIV and AIDS data, enabling greater understanding of the clinical status of persons diagnosed with HIV. This approach increases possibilities for longer-term monitoring of outcomes of the HIV continuum of care such as linkage to care, treatment and viral suppression following diagnosis and can support national and global efforts to monitor progress towards the 90-90-90 targets. xiii HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Обзор эпидемиологической ситуации по ВИЧ/СПИДу в Европе Несмотря на возможность предотвращения ВИЧ путем проведения эффективных мер общественного здравоохранения, в Европе продолжается значительное распространение вируса иммунодефицита человека. В 2014 году в 50 из 53 стран Европейского региона ВОЗ было зарегистрировано 142 197 новых случаев ВИЧ-инфекцииi. Сорок девять стран официально предоставили ЕЦКЗ/Европейскому региональному бюро ВОЗ сведения о 56 945 случаях, в том числе о 29 992 случаях из стран-членов Европейского союза и Европейской экономической зоны (ЕС/ЕЭЗ). Данные еще о 85 252 новых случаях в 2014 г. были опубликованы Российским федеральным научно-методическим центром по профилактике и борьбе со СПИДом [1]. В 50 странах частота новых случаев ВИЧ-инфекции составила 16,4 на 100 000 населения (Таблица А). Наличие источника приведенных данных по России позволило включить российские сведения в ежегодные и сводные региональные итоговые значения и показатели по ВИЧ-инфекции, в ссылки на ежегодные и сводные итоговые значения и показатели стран, в данные о путях передачи вируса, а также включить сводные итоговые данные по диагностике СПИДа в общие региональные показатели. Все другие региональные показатели по ВИЧ и все данные по СПИДу за 2014 г., представленные в этом докладе, основаны на информации, полученной от 49 стран, предоставляющих свои сведения в ЕЦКЗ/ВОЗ. i Нет данных от Боснии и Герцеговины, Туркменистана и Узбекистана. Один случай из Лихтенштейна включен в общее число новых случаев ВИЧ-инфекции, представленных в этом докладе, но поскольку Лихтенштейн не является государствомчленом Европейского региона ВОЗ, данные от этой страны не вошли в состав итоговых значений по западной, центральной и восточной частям Европейского региона ВОЗ. Среди 49 странii, официально предоставивших отчетные данные, частота случаев составила 7,9 на 100 000 населения и 5,9 на 100 000 населения для стран ЕС/ ЕЭЗ (Рис. А). Как и за последние годы, показатели и общее число людей с установленным диагнозом ВИЧ были самыми высокими в восточной части Региона, а самыми низкими – в центральнойiii (Таблица A). Основной путь передачи вируса различается по географическим зонам, что указывает на широкое разнообразие эпидемиологической ситуации с ВИЧинфекцией в Европе. В странах ЕС/ЕЭЗ доминирует передача ВИЧ при сексуальных контактах между мужчинами, а основным путем передачи вируса в восточной части Региона является гетеросексуальный. В Европейском регионе ВОЗ 31% новых случаев ВИЧ был зарегистрирован среди людей, которые не являлись выходцами из страны, включившей их в отчетные данные, из них 22% людей были рождены за пределами Европейского региона ВОЗ, а 9% - были выходцами из европейской страны, отличной от той, что включила их в отчет. В период между 2005 и 2014 годами число новых случаев ВИЧ-инфекции среди неместного населения сократилось в целом на 28%. Анализ этой тенденции по региону происхождения указывает на то, что число новых случаев ВИЧ-инфекции среди мигрантов, рожденных за пределами Европейского региона ВОЗ, сократилось на 41%, но увеличилось на 48% среди европейских мигрантов (т.е. людей, рожденных в одной из стран ii Нет данных от Боснии и Герцеговины, России, Туркменистана и Узбекистана. iii Группировка стран Региона по принципу «Запад» (23 страны), «Центр» (15 стран) и «Восток» (15 стран) основана на эпидемиологических данных и следует делению стран на группы, которое использовалось в предыдущих докладах, публикуемых EuroHIV с 1984 года: Для получения более подробной информации смотрите Приложение 1, Рис. A1. Таблица A: Характеристики случаев ВИЧ-инфекции, зарегистрированных в Европейском регионе ВОЗ, в ЕС/ЕЭЗ, в западной, центральной и восточной частях Европейского региона ВОЗ, 2014 Европейский регион ВОЗ Страны, предоставившие отчетные данные/Число стран Число новых случаев ВИЧ-инфекции Частота случаев на 100 000 населения Процент случаев у людей в возрасте 15-24 лет Соотношение мужчины/женщины Путь передачи инфекции Сексуальные контакты между мужчинами Гетеросексуальные контакты Употребление инъекционных наркотиков От матери ребенку Путь неизвестен Западная часть Центральная часть Восточная часть ЕС/ЕЭЗ 49/53 (50/53) 23/23 14/15 12/15 (13/15) 31/31 56 972 (142 197) 7.9 (16.4) 10.2% 2.2 27 325 6.4 10.6% 3.3 4950 2.6 14.9% 4.4 24 669 (109 930) 22 (43.2) 8.7% 1.4 29 992 5.9 11.1% 3.3 24.4% 46.8% 14.0% 1.0% 13.5% 43.9% 33.7% 3.1% 0.8% 18.1% 28.0% 24.3% 5.4% 1.0% 40.9% 2.2% 66.0% 27.8% 1.2% 2.9% 42.3% 32.8% 4.1% 0.8% 19.7% Данные не были получены от Боснии и Герцеговины, России, Туркменистана и Узбекистана. Все представленные данные поступили в ЕЦКЗ/ВОЗ через Европейскую систему эпиднадзора (TESSy), за исключением данных по России, которые были получены от Российского федерального научно-методического центра по профилактике и борьбе со СПИДом [1]. Российские данные включены в цифры по Европейскому региону и его восточной части, они указаны в круглых скобках. * Цифры, включающие данные по России, представлены в скобках в колонках по Европейскому региону ВОЗ и по его восточной части xiv HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Европы, отличной от той, что включила их в отчет) (Рис. C, Таблица 11). соотношения отмечают в Словении (15,0), Венгрии (10,6), Хорватии (9,2), Чешской Республике (9,1) и на Мальте (9,0) (Рис. 1.1). Преобладающим путем передачи вируса в этих странах являются сексуальные контакты между мужчинами (Рис. 1.5). В 2014 году в 47 странах i Европейского региона ВОЗ было диагностировано 16 037 случаев СПИДа (данные по России отсутствуют), а частота новых случаев составила 2,3 на 100 000 населения для Европейского региона ВОЗ и 0,8 на 100 000 населения для ЕС/ЕЭЗ. Несмотря на то, что в западной части Региона и в ЕС/ЕЭЗ число случаев СПИДа продолжает устойчиво снижаться, на востоке Региона за последнее десятилетие оно увеличилось почти вдвое. Наивысший общий показатель диагностики ВИЧинфекции по отдельным возрастным группам наблюдался среди людей в возрасте 25-29 лет (14,6 на 100 000 населения), при этом пиковые значения у мужчин и женщин в этой возрастной группе составили 22,7 и 6,2 на 100 000 населения, соответственно (Рис. 1.2). Европейский союз и Европейская экономическая зона Как и в предыдущие годы, самая высокая доля случаев ВИЧ-инфекции зарегистрирована среди мужчин, практикующих секс с мужчинами (МСМ) – 42%, а вторым наиболее распространенным путем передачи ВИЧ стали гетеросексуальные контакты (33%). Распространение ВИЧ-инфекции вследствие потребления инъекционных наркотиков привело к появлению 4% новых случаев ВИЧ-инфекции, и почти в 20% случаев путь передачи вируса был неизвестен (Таблица А). От общего числа диагностированных людей, более трети (37%) зарегистрировано среди тех, кто был рожден за пределами страны, предоставившей отчетные данные (Рис.1.6). Однако здесь наблюдаются широкие колебания от 82% в Исландии и 78% в Швеции до менее 5% случаев в Венгрии, Латвии, Польше, Румынии, Словацкой Республике, Хорватии и Эстонии. В 2014 году диагноз ВИЧ был установлен у 29 992 человек в 31 стране ЕС/ЕЭЗ, что составляет 5,9 случаев на 100 000 населения (6,4 на 100 000 населения с поправкой на задержки в предоставлении данных) (Таблица 1). Страны с самой высокой частотой новых случаев ВИЧ-инфекции, зарегистрированных в 2014 году, это Эстония (22,1; 291 случай), Латвия (17,3; 347 случаев) и Люксембург (12,6; 69 случаев). Самые низкие показатели ВИЧ-инфицирования были зарегистрированы в Словакии (1,6; 86 случаев), Хорватии (2,2; 92 случая) и Чешской Республике (2,2; 232 случая). Частота новых случаев ВИЧ-инфекции была выше среди мужчин (9,2 на 100 000 населения; Таблица 2), чем у женщин (2,6 на 100 000 населения; Таблица 3). В целом соотношение случаев у мужчин и женщин составило 3,3 (Таблица A). Наивысшее значение этого Несмотря на постоянную работу по профилактике и ресурсы, выделяемые странами ЕС/ЕЭЗ, за последнее десятилетие было отмечено лишь весьма незначительное снижение числа случаев ВИЧ-инфекции на 100 000 населения, частота которых в 2005 году составил 6,7 на 100 000 населения (29 129 случаев) по сравнению с 6,4 на 100 000 населения (32 605 i Нет данных от Боснии и Герцеговины, России, Сан-Марино, Швеции, Туркменистана и Узбекистана. Рис. A: Частота зарегистрированных новых случаев ВИЧ-инфекции на 100 000 населения, с разбивкой по году постановки диагноза, в ЕС/ЕЭЗ и в Европейском регионе ВОЗ*, 1984–2013 гг. – с поправкой на задержки в предоставлении данных 9 Европейский регион ВОЗ случаи на 100 000 населения 8 ЕС/ЕЭЗ 7 6 5 4 3 2 1 0 1984 Количест во стран, которые подали 15 отчет 1986 1988 1990 1992 1994 1996 1998 2000 2002 2004 2006 2008 2010 2012 2014 Год постановки диагноза 25 27 36 36 39 42 42 42 42 44 43 45 48 48 47 47 49 46 50 52 52 52 51 52 52 53 51 51 49 49 Из-за задержки сообщения в ближайшие годы частота может увеличиться. * Данные по Российской Федерации не включены. xv HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT случаев) в 2014 году - с поправкой на задержки в предоставлении данных (Таблица 1, Приложение 6). Тенденции в отношении путей передачи инфекции указывают на то, что число случаев ВИЧ-инфекции среди МСМ в странах с систематической отчетностью увеличилось в ЕС/ЕЭЗ в целом (Таблица 8; Рис. 1.9). При этом за последнее десятилетие устойчивый рост наблюдался во всех кроме шести стран ЕС/ЕЭЗ (Таблица 4). Число случаев, относимых к МСМ, увеличилось за этот период как среди мужчин, рожденных в стране, предоставившей отчетные данные, так и среди мужчин, рожденных за ее пределами (Рис. 1.10). Число случаев ВИЧ-инфекции, возникших в результате гетеросексуальных контактов, за последнее десятилетие сократилось на 40%, при этом более резкое снижение наблюдалось среди людей, рожденных за пределами страны, предоставившей отчетные данные, в особенности среди выходцев из стран с генерализованной эпидемией ВИЧ (Таблица 8, Рис. 1.10). Число случаев среди людей, инфицированных ВИЧ вследствие потребления инъекционных наркотиков, за этот период сократилось на 44% (Таблица 8). Общий рост числа случаев, отнесенных к потреблению инъекционных наркотиков, наблюдался в 2011 и 2012 годах и был вызван локальными вспышками в Греции и Румынии (Таблица 5). Однако число случаев, зарегистрированных в этих странах в 2013 и 2014 гг., указывает на продолжающуюся тенденцию к снижению. В период с 2005 по 2014 годы число случаев передачи ВИЧ-инфекции от матери ребенку, а также число случаев нозокомиального заражения или заражения путем переливания крови постоянно снижалось, оставаясь на уровне менее 1% диагностированных случаев (Таблица 8). В 2014 г. информация о числе клеток CD4 на момент постановки диагноза ВИЧ была получена от 22 стран (Таблица 14) для 18 411 (61%) диагностированных людей в возрасте >14 лет и старше (Таблица 14). Почти половина (47%) всех людей с установленным диагнозом и информацией об уровне клеток CD4 на момент постановки диагноза имела зарегистрированное число клеток CD4 менее 350 на мм3, из них 27% случаев находились на продвинутой стадии ВИЧ-инфекции (CD4 <200 клеток/мм3). Среди всех диагностированных случаев с данными о числе клеток CD4, у 20% уровень CD4 был в диапазоне от 350 до 500 клеток на мм3, а у 33% - от 500 и более клеток CD4 на мм3 (Рис. 1.7). При анализе уровня клеток CD4 и путей передачи инфекции доля диагнозов, поставленных на более поздней стадии (CD4 <350 клеток/мм), была самой высокой у людей, потребляющих инъекционные наркотики (61%) (Рис. 1.8). Самая низкая доля диагнозов, поставленных при уровне CD4 ниже 350 клеток на мм3, была зарегистрирована среди тех, кто инфицировался в результате сексуальных контактов между мужчинами (37%). Доля случаев, диагностированных при количестве клеток CD4 на уровне 350 на мм3 и менее, увеличивается с возрастом - шестидесяти одному проценту людей в возрасте 50 лет и старше диагноз ВИЧ был установлен, когда число клеток CD4 составляло 350 клеток на мм3 и ниже. По сравнению с коренными жителями (46%) или другими группами мигрантов (Рис. 1.8), более высокие доли людей из стран Африки, расположенных к югу от Сахары (57%), из Южной и Юго-Восточной Азии (57%) на момент постановки диагноза имели число клеток CD4 менее 350 на мм3. В 2014 году в 31 стране ЕС/ЕЭЗ было диагностировано 4 020 случаев СПИДа. Таким образом, частота случаев составила 0,8 на 100 000 населения (Таблица 15). Данные о самых высоких показателях поступили из Латвии (8,5) и Португалии (2,4). С середины 1990-х годов число случаев СПИДа в ЕС/ЕЭЗ последовательно снижается. Среди 20 стран ЕС/ЕЭЗ, где удалось полностью установить связь между случаями ВИЧ-инфекции и СПИДа в 2014 г., 69% случаев СПИДа возникли во время или в течение 90 дней после поставки диагноза ВИЧ. При этом процентное значение варьировалось от 100% зарегистрированных Рис. B: Совокупное число новых случаев ВИЧ-инфекции в ЕС/ЕЭЗ и других странах Европейского Региона ВОЗ*, 1984-2014 1000000 ЕС/ЕЭЗ Другие страны Европейского региона ВОЗ Число случаев 800000 600000 400000 200000 0 1985 1990 1995 2000 Год постановки диагноза Данные по Российской Федерации не включены. xvi 2005 2010 2014 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Рис. C: Новые случаи ВИЧ-инфекции среди людей, не являющихся мигрантами, а также среди европейских и других мигрантов с поправкой на задержки в предоставлении данных, Европейский регион ВОЗ, 2005-2014 Люди, не являющиеся мигрантами ( выходцы из страны, предоставившей отчетные данные) 15000 Другие мигранты (выходцы из стран за пределами Европейского региона ВОЗ) Число случаев 20000 Европейские мигранты (выходцы из европейской страны, отличной от той, что предоставила отчетные данные) 10000 5000 0 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Год постановки диагноза Данные из Болгарии, Италии, Испании, России, Узбекистана, Украины Туркменистана и Эстонии исключены вследствие непоследовательной или неполной отчетности по данным о стране происхождения или регионе происхождения за указанный период времени. случаев СПИДа (Дания, Кипр, Норвегия и Словакия) до почти 47% впервые установленных диагнозов СПИДа в Австрии и Бельгии и 26% - в Латвии (Рис. 1.13). Европейский регион ВОЗ В 2014 г. в Европейском регионе ВОЗ было зарегистрировано 142 197 новых случаев ВИЧ-инфекции – это самое высокое годовое значение, зарегистрированное с момента начала отчетности в 1980-х. Таким образом, совокупное число диагностированных случаев ВИЧ-инфекции в Европейском регионе ВОЗ увеличилось до 1 840 136. В это число вошло 995 175 диагностированных случаев, о которых было официально сообщено в объединенную систему эпиднадзора ЕЦКЗ и Европейского регионального бюро ВОЗ (Рис. В), и 907 607 случаев инфекции, диагностированных в Россииi [1]. Из 142 197 человек с впервые установленным диагнозом ВИЧ-инфекции в 2014 г. в 50 странах ii, 77% было диагностировано в восточной части (109 921), 19% - в западной (27 325) и 3% - в центральной части Региона (4 950) (Таблица A). Частота случаев была также самой высокой в восточной части (43,2 на 100 000 населения), что значительно выше, чем в западной (6,4 на 100 000) и центральной части (2,6 на 100 000) (Таблица A). В 49 странах, предоставляющих данные отчетности в ЕЦКЗ/ВОЗiii, 43% новых диагностированных случаев (24 669) было зарегистрировано на востоке Региона, при этом частота случаев составила 22,0 на 100 000 населения, 48% - в западной части и 9% - в центральной части Региона. У мужчин региональная частота случаев составила 11,1 на 100 000 населения i Минус 62 581 случай, официально представленный в ЕЦКЗ/ВОЗ Россией в 2010 г. ii Нет данных от Боснии и Герцеговины, Туркменистана и Узбекистана iii Нет данных от Боснии и Герцеговины, России, Туркменистана и Узбекистана. (Таблица 2), а у женщин - 4,7 на 100 000 населения (Таблица 3). Показатели новых диагностированных случаев ВИЧинфекции в 2014 году значительно варьируются по странам Европейского региона ВОЗ. В России этот показатель составил 58,4 на 100 000 населения и стал самым высоким в Регионе [1]. Среди стран, предоставляющих отчетные данные в ЕЦКЗ/ВОЗ, самые высокие показатели были зарегистрированы в Украине (36,9)iv, Эстонии (22,1), Молдове (20,4), Беларуси (19,1), Латвии (17,3), Казахстане (13,5), Грузии (13,3), Люксембурге (12,6), Таджикистане (11,9) и Кыргызстане (11,0), а самые низкие – в бывшей югославской Республике Македония (1,4), Сербии (1,4), Словакии (1,6), Хорватии (2,2), Чешской Республике (2,2), Турцииv (2,3) и Словении (2,4) (Таблица 1). В странах, предоставляющих свои отчетные данные, большая часть новых случаев ВИЧ-инфекции (36%) зарегистрирована в возрастной группе 30–39 лет, а 10% – в возрастной группе 15–24 года. Соотношение случаев у мужчин и женщин составило 2,2 – с самым низким значением в восточной части Региона (1,4), выше - на западе (3,3) и с самым высоким значением в центральной части Региона (4,4) (Таблица А). Чаще всего инфицирование происходило при гетеросексуальных контактах (47%), включая 13% случаев среди выходцев из стран с генерализованной эпидемией. У 24% случаев заражение произошло при сексуальных контактах между мужчинами, у 14% - при употреблении инъекционных наркотиков, и 1% новых случаев инфицирования был обусловлен передачей вируса от матери ребенку. Информация о пути заражения отсутствовала у 13% новых случаев ВИЧ-инфекции. iv За исключением данных по Крыму и г. Севастополю v Данные по ВИЧ в Турции не включают случаи СПИДа, диагностированные на момент постановки диагноза ВИЧ, поэтому они не являются полностью совместимыми с данными по другим странам. xvii HIV/AIDS surveillance in Europe 2014 В восточной части Региона основными путями распространения ВИЧ-инфекции были гетеросексуальные контакты и потребление инъекционных наркотиков (66% и 28% новых случаев, соответственно), а зарегистрированный уровень распространения ВИЧ посредством сексуальных контактов между мужчинами остается очень низким (2% случаев). В России среди новых случаев ВИЧ-инфекции с известным путем передачи вирусаi (это около половины случаев [2]), 57% были инфицированы в результате потребления инъекционных наркотиков, 40% - через гетеросексуальные контакты, 1% - в результате сексуальных контактов между мужчинами и 0,1% - вследствие передачи вируса от матери ребенку [1]). Большое число новых случаев ВИЧ-инфекции в России среди людей, инфицированных в результате потребления инъекционных наркотиков, подчеркивает значимую роль этого пути передачи вируса в восточной части Региона. В центральной части Региона сексуальные контакты между мужчинами (28%) и гетеросексуальные контакты (24%) были основными путями передачи ВИЧ-инфекции, при этом преобладающим путем в 10 из 14 стран были сексуальные контакты между мужчинами, в то время как у 41% новых случаев путь передачи вируса был неизвестен. В западной части Региона сексуальные контакты между мужчинами оставались основным путем передачи ВИЧ-инфекции (44% новых случаев), за которым следовал гетеросексуальный путь (34% новых случаев). В целом, в период с 2005 по 2014 год в 50 странах (включая Россию [1]) частота впервые диагностированных случаев ВИЧ-инфекции увеличилась на 59% - с 10,3 на 100 000 населения (80 652 случая) до 16,4 на 100 000 населения (142 197 случаев). Такой прирост обусловлен главным образом тенденцией к росту в восточной части Региона, где частота случаев продолжает увеличиваться, а прирост составляет 115% - с 20,1 на 100 000 населения в 2005 г. (51 058 случаев) до 43,2 на 100 000 населения в 2014 г. (109 921 случай). В 49 странах ii, предоставивших данные в ЕЦКЗ и ВОЗ, частота случаев для Региона увеличилась на 11% - с 7,1 в 2005 г. (45 251 случай) до 7,9 в 2014 г. (56 945 случаев); в восточной части региона частота увеличилась на 59% - с 14,1 в 2005 г. (15 657 случаев) до 22,3 в 2014 году (24 669 случаев). В центральной части частота увеличилась на 117% это самый большой относительный прирост из всех трех географических зон - с 1,2 (2 165 случаев) до 2,6 (4 950 случаев), тогда как в западной части Региона произошло снижение частоты на 20% - с 8,0 (27 429 случаев) в 2005 г. до 6,4 (27 325 случаев) в 2014 году. i Этот подход к анализу отличается от остальных подходов, используемых в докладе, где случаи с неизвестным путем передачи ВИЧ показаны отдельно и включены в знаменатель для вычисления процентов. По этой причине проценты по России не полностью сопоставимы с процентами по другим странам или группам стран в этом докладе. ii Нет данных от Боснии и Герцеговины, России, Туркменистана и Узбекистана. xviii SURVEILLANCE REPORT Тенденции, наблюдаемые в путях передачи вируса в 44 странах, которые располагают последовательными даннымиiii, указывают на рост числа людей, инфицирование которых произошло в результате гетеросексуальных контактов (увеличение на 28%) и сексуальных контактов между мужчинами (увеличение на 28%), в то время как число случаев инфицирования вследствие потребления инъекционных наркотиков снизилось на 22%. На востоке Региона число случаев инфицирования в результате гетеросексуальных контактов увеличилось на 171% и в 10 раз – при передаче вируса во время сексуальных контактов между мужчинами, в то время как число случаев ВИЧ-инфицирования вследствие потребления инъекционных наркотиков сократилось на 17% по сравнению с 2005 годом. Вместе с тем, число новых случаев ВИЧ-инфекции у женщин увеличилось на 74%, а у мужчин - на 49%. В центральной части Региона число людей, инфицированных в результате сексуальных контактов между мужчинами, увеличилось более чем в три раза, на 26% увеличилось распространение вируса гетеросексуальным путем, и в шесть раз - в связи с употреблением инъекционных наркотиков, вследствие вспышки в Румынии, которая началась в 2011 году, достигла своего пика в 2012 году, после чего пошла на спад. На западе Региона распространение вируса в результате сексуальных контактов между мужчинами увеличилось на 15%, тогда как число случаев передачи ВИЧ-инфекции гетеросексуальным путем сократилось на 44% (при этом более резкий спад наблюдался среди выходцев из стран с генерализованной эпидемией) и на 60 % при потреблении инъекционных наркотиков. Почти половина (48%) людей (>14 лет) с впервые установленным диагнозом, по которым на момент постановки диагноза ВИЧ имелась информация об уровне клеток CD4, были случаями позднего обращения, когда количество клеток CD4 составляло менее 350 на мм3, из них 28% новых случаев было диагностировано на продвинутой стадии ВИЧинфекции (CD4<200/мм3). У 20% случаев уровень CD4 был в диапазоне от 350 до 500 клеток на мм3, а у 32% - число клеток CD4 было на уровне 500 и более на мм3. Процент поздних обращений варьировался по категориям распространения ВИЧ-инфекции и был наивысшим среди людей, инфицированных в результате потребления инъекционных наркотиков (64%), далее следуют случаи передачи вируса через гетеросексуальные контакты (56%), и самый низкий процент – у мужчин, инфицированных в результате сексуальных контактов между мужчинами (37%). Процент людей, диагноз которым был поставлен при количестве клеток CD4 на уровне или ниже 350/ мм3, с возрастом увеличивался, и у 61% людей в возрасте 50 лет и старше диагноз ВИЧ-инфекции был iii Исключены данные из Эстонии, Польши и Турции, т.к. у них отсутствует более 50% данных о путях распространения вируса; данные из Испании и Италии были исключены, поскольку за этот период времени увеличился охват их систем эпиднадзора; данные из Боснии и Герцеговины, России, Туркменистана и Узбекистана не были сообщены. SURVEILLANCE REPORT поставлен, когда число клеток CD4 было на уровне или ниже 350 клеток на мм3. В 2014 году в 47 странах Европейского региона ВОЗi было диагностировано 16 037 случаев СПИДа; частота случаев составила 2,3 на 100 000 населения. В Восточной части Региона было диагностировано 74% случаев (11 890), на западе Региона - 20% (3 214), и 6% (932) в его центральной части. Частота случаев была самой высокой также на востоке Региона (10,7 на 100 000 населения), что в 13 раз выше, чем в западной части (0,8 на 100 000) и в 21 раз выше, чем в центральной части (0,5 на 100 000 населения). В период между 2005 и 2014 годами частота новых случаев СПИДа в Регионе сократилась на 4% - с 2,3 (14 294 случая) до 2,2 (16 037 случаев). При этом большие колебания наблюдаются по трем географическим зонам: увеличение на 143% - на востоке Региона - с 4,4 (4 926 случаев) до 10,7 (11 890 случаев) на 100 000 населения, увеличение на 25% в центральной части Региона- с 0,4 (751 случай) до 0,5 (932 случая) на 100 000 населения, и стабильное снижение на 69% в западной части Региона - с 2,6 (8 617 случаев) до 0,8 (3 214 случаев) на 100 000 населения. Выводы Распространение ВИЧ-инфекции продолжает вызывать серьезную обеспокоенность в Европе, в особенности в восточной части Европейского региона ВОЗ. В 2014 г. диагноз ВИЧ был установлен у более 142 000 человек - это самое большое число новых случаев ВИЧ-инфекции, когда-либо зарегистрированных за один год. Из них 77% случаев было диагностировано в восточной части Региона, и 21% - в ЕС/ЕЭЗ. Последние данные эпиднадзора указывают на то, что, несмотря на значительные усилия по профилактике и контролю ВИЧ, большого снижения числа новых случаев ВИЧ-инфекции в западной части Региона и в ЕС/ЕЭЗ не произошло, а в восточной части Региона за последнее десятилетие это число увеличилось более чем в два раза. В центральной части Региона число новых случаев остается на более низком уровне, чем на востоке и на западе, однако за последнее десятилетие оно также увеличилось более чем вдвое. Несмотря на то, что модели и тенденции эпидемии в странах Европы значительно различаются, в западной и центральной части Региона наблюдался значительный рост числа случаев инфицирования среди мужчин, имеющих сексуальные контакты с мужчинами, в восточной части региона – среди людей, инфицированных вследствие гетеросексуальных контактов, в особенности среди женщин. Число случаев передачи вируса в результате потребления инъекционных наркотиков продолжает сокращаться, однако именно этот путь стал причиной возникновения более четверти новых случаев ВИЧ-инфекции i Нет данных от Боснии и Герцеговины, России, Сан-Марино, Туркменистана, Узбекистана и Швеции. HIV/AIDS surveillance in Europe 2014 в восточной части Региона. В то же время, сокращается число новых случаев ВИЧ-инфекции среди людей, рожденных за пределами страны, предоставившей отчетные данные, и особенно - среди рожденных за пределами Европейского региона. В 2015 г. были выпущены руководящие принципы по лечению ВИЧ-инфекции, в которых рекомендуется начинать антиретровирусную терапию (АРТ) всем людям, живущим с ВИЧ, вне зависимости от числа клеток CD4 [3]. В настоящее время существуют доказательства того, что раннее начало лечения благотворно влияет на здоровье людей, получающих терапию, и предотвращает дальнейшее распространение ВИЧ-инфекции [4, 5]. Однако слишком большому числу людей (48%) в Европейском регионе ВОЗ диагноз устанавливают на поздней стадии, что ведет к риску ухудшения состояния здоровья, смерти и дальнейшему распространению ВИЧ-инфекции. Высокий и тревожный рост числа случаев СПИДа в восточной части Региона также указывает на то, что поздняя постановка диагноза ВИЧ, запоздалое начало АРТ и низкий охват лечением остаются главными проблемами. Для сокращения числа случаев поздней диагностики нужны новые стратегии для оказания расширенных, целенаправленных услуг тестирования на ВИЧ. Новые сводные руководства ВОЗ для служб тестирования на ВИЧ [6] дают новые рекомендации в поддержку проведения тестирования на ВИЧ обученными волонтерами (тестирование на ВИЧ на базе местных сообществ) в дополнение к тестированию, проводимому по инициативе медицинских работников. В них рассматриваются потенциальные возможности проведения самостоятельного тестирования на ВИЧ для повышения охвата тестированием и его доступности, а также целенаправленные стратегические подходы к оказанию услуг по тестированию на ВИЧ, которые необходимы для поддержки первого из трех целевых ориентиров ООН «90-90-90» (90% людей, живущих с ВИЧ, знают свой статус) [7]. Эти услуги должны быть сосредоточены на группах населения, особенно подверженных ВИЧ-инфицированию в местном эпидемическом контексте. Они должны удовлетворять конкретные потребности этих групп и способствовать установлению своевременной связи с профилактикой, лечением ВИЧ и оказанием ухода. Такой подход обеспечит раннюю диагностику и своевременное начало лечения, что в конечном итоге приведет к улучшению результатов лечения, сокращению болезненности, смертности, заболеваемости ВИЧ и будет способствовать достижению второго и третьего целевого ориентира «90-90-90» (90% диагностированных ЛЖВ получают АРТ, и 90% людей, получающих АРТ, достигают вирусной супрессии). Меры по противодействию эпидемии должны быть основаны на научных данных и адаптированы к национальным и местным эпидемиологическим условиям. На основании данных эпиднадзора, представленных в этом докладе, можно сделать следующие выводы: xix HIV/AIDS surveillance in Europe 2014 • Принимая во внимание устойчивый рост числа случаев ВИЧ-инфекции среди МСМ, наблюдаемый за последнее десятилетие, странам ЕС/ЕЭЗ и западной части Региона необходимо укреплять и расширять существующие мероприятия по профилактике и борьбе с ВИЧ-инфекцией, которые должны оставаться основой мер реагирования на ситуацию с ВИЧ. Многокомпонентные меры вмешательства, в том числе новые стратегии, такие как включение предэкспозиционной профилактики ВИЧ (ПрЭП) в общий набор мероприятий по профилактике, могут помочь в сдерживании этой растущей тенденции [8, 9, 10]. Рост числа случаев ВИЧ-инфекции среди людей, потребляющих инъекционные наркотики, который наблюдается в последнее время в ряде стран [2,3], указывает на необходимость поддерживать проведение или расширение масштабов программ по снижению вреда. • В странах центральной части Региона эпидемия сохраняется на низком уровне, но имеет более высокий относительный прирост, чем в других частях Европы. Он обусловлен ростом числа случаев инфицирования в результате сексуальных контактов, главным образом среди МСМ, но также и вследствие гетеросексуальных контактов; 4 из 5 новых случаев ВИЧ-инфекции регистрируют у мужчин, и приоритетом здесь является укрепление и целенаправленное проведение целого ряда мер по профилактике, тестированию и лечению ВИЧ-инфекции в этой относительно широкой группе населения. Ключевую роль в достижении поставленной цели будут играть усилия по сокращению стигмы и дискриминации. • Для стран восточной части Региона существует срочная необходимость расширять масштабы действий, основанных на фактических данных, и оказывать эффективные и всеобъемлющие услуги через системы здравоохранения, которые успешно воздействуют на социальные детерминанты здоровья. • Людям, подверженным риску гетеросексуальной передачи ВИЧ-инфекции, а также людям, употребляющим инъекционные наркотики, необходимо обеспечить полный охват эффективными услугами по профилактике, а всем нуждающимся следует предоставлять услуги целевого тестирования на ВИЧ, доступ к консультированию и комплексному уходу. В парах, где у одного из партнеров отмечают поведение повышенного риска (потребление инъекционных наркотиков, использование коммерческих сексуслуг, бисексуальные отношения или длительная работа за границей), более активные меры должны помочь направить усилия на сокращение риска распространения вируса гетеросексуальным путем. К числу таких мер относят предэкспозиционную профилактику ВИЧ-инфекции там, где это уместно и согласуется с рекомендациями ВОЗ [3,11]. Доказательные практики, нацеленные на ключевые xx SURVEILLANCE REPORT группы населения и, в частности, на потребителей инъекционных наркотиков, включают программы по снижению вреда. Их следует поддерживать как основополагающие элементы ответных действий, направленных на ВИЧ-инфекцию. Доступность антиретровирусной терапии следует расширять для лечения и профилактики распространения ВИЧ-инфекции, а также для сокращения растущего числа случаев СПИДа. • Несмотря на то, что с 2005 года число случаев ВИЧ среди мигрантов значительно сократилось, 31% диагнозов регистрируют среди людей, рожденных за границей, из них 22% являются выходцами из стран, расположенных за пределами Европейского региона ВОЗ. С 2005 года число новых случаев ВИЧ-инфекции среди всех мигрантов в целом сократилось на 28% и на 41% - среди людей, которые являются выходцами из стран, расположенных за пределами Европы. Существуют доказательства того, что значительная доля мигрантов инфицируется ВИЧ после миграции в Европейский регион [12, 13, 14]. Поэтому странам по-прежнему важно обеспечивать мигрантам доступность мер по профилактике, лечению и уходу. И наконец, для проведения точного и своевременного мониторинга и обоснованного выбора мер общественного здравоохранения в ответ на эпидемию ВИЧ в Европе необходимы надежные данные эпиднадзора. Со временем происходит постепенное увеличение числа стран, осуществляющих усиленный эпиднадзор за ВИЧ и отчитывающихся по данным эпиднадзора на уровне Европы. Впервые в 2014 году 33 страны предоставили объединенные данные по ВИЧ и СПИДу, позволяющие лучше понять клинический статус людей с установленным диагнозом ВИЧ. Этот подход расширяет возможности для проведения долгосрочного мониторинга результатов континуума медицинской помощи, таких как связь с помощью, лечением и вирусной супрессией после установления диагноза; он также способен поддержать национальные и глобальные усилия, направленные на проведение мониторинга успехов на пути достижения целевых ориентиров ОНН: 90-90-90. Ссылки 1 Российский федеральный научно-методический цент по профилактике и борьбе со СПИДом. Информационная записка «Справка. ВИЧ-инфекция в Российской Федерации», 2014. Москва: Российский федеральный научно-методический центр по профилактике и борьбе со СПИДом; 2015. Смотрите на сайте: http://hivrussia.org/files/spravkaHIV2014.pdf. 2 Hedrich D, Kalamara E, Sfetcu O, Pharris A, Noor A, Wiessing L, et al. Human immunodeficiency virus among people who inject drugs: Is risk increasing in Europe? Euro Surveill. 2013;18(48):pii=20648. Смотрите на сайте: http://www.eurosurveillance.org/ViewArticle. aspx?ArticleId=20648 3 World Health Organization. Guidelines on when to start antiretroviral therapy and on pre-exposure prophylaxis for HIV. Geneva: World Health Organization; 2015. http://apps.who.int/iris/bitstr eam/10665/186275/1/9789241509565_eng.pdf 4 INSIGHT START Study Group. Initiation of antiretrovial therapy in early asymptomatic HIV infection. N Engl J Med. 2015;373 (9) :795-807. 5 Cohen MS, Chen YQ, McCauley M, Gamble T, Hosseinipour MC, Kumarasamy N, et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med. 2011;365(6):493-505. SURVEILLANCE REPORT 6 HIV/AIDS surveillance in Europe 2014 World Health Organization. Consolidated guidelines on HIV testing services. Geneva: World Health Organization; 2015. 7 UNAIDS. Ambitious treatment targets: Writing the final chapter of the AIDS epidemic. Geneva; 2014. Смотрите на сайте: h t t p://w w w. u n a i d s .o r g /s i t e s/d e f a u l t /f i l e s/m e d i a _ a s s e t / JC2670_UNAIDS_Treatment_Targets_en.pdf 8 European Centre for Disease Prevention and Control. HIV and STI prevention among men who have sex with men. ECDC Guidance. Stockholm: ECDC; 2014. Смотрите на сайте: http://ecdc.europa. eu/en/publications/Publications/hiv-sti-prevention-among-menwho-have-sex-with-men-guidance.pdf 9 Всемирная организация здравоохранения. Сводное руководство по использованию антиретровирусных препаратов для лечения и профилактики ВИЧ-инфекции. Краткий обзор основных особенностей и рекомендаций. Женева: Всемирная организация здравоохранения; 2013. 10 McCormack S, Dunn DT, Desai M, Dolling DI, Gafos M, Gilson R, et al. Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial. Lancet. 2015 Sep 9. pii: S0140-6736(15)00056-2[Epub ahead of print]. 11 World Health Organization. Consolidated guidelines on HIV prevention, diagnosis, treatment and care for key populations. Geneva: World Health Organization; 2014. 12. Rice BD, Elford J, Yin Z, Delpech VC. A new method to assign country of HIV infection among heterosexuals born abroad and diagnosed with HIV. AIDS 2012; 26(15):1961-1966. 13. Fakoya I, Alvarez-del Arco D, Woode-Owusu M, Monge S, RiveroMontesdeoca Y, Delpech V, et al. A systematic review of postmigration acquisition of HIV among migrants from countries with generalised HIV epidemics living in Europe: implications for effectively managing HIV prevention programmes and policy. BMC Public Health, 2015; 15: 561. 14. Alvarez-del Arco D; Fakoya I; Monge S; Gennotte AF; Touloumi G; Zuure F; Barros H, et al. HIV Acquisition among migrants living in Europe: Results from aMASE (Advancing Migrant Access to Health Services in Europe). Устная презентация на 15-й Европейской конференции по СПИДу; 21-24октября 2015; Барселона, Испания. xxi HIV/AIDS surveillance in Europe 2014 xxii SURVEILLANCE REPORT SURVEILLANCE REPORT HIV/AIDS surveillance in Europe 2014 1 HIV and AIDS in the European Union and European Economic Area 1.1 HIV diagnoses In 2014, 29 992 new HIV diagnoses were reported by all the 31 EU/EEA countries, with a rate of 5.9 per 100 000 population (6.4 per 100 000 when adjusted for reporting delay) (Table 1). The highest rates were reported by Estonia (22.1; 291 cases), Latvia (17.3; 347 cases), and Luxembourg (12.6; 69 cases). The lowest rates were reported by Slovakia (1.6; 86 cases), Croatia (2.2; 92 cases), and the Czech Republic (2.2; 232 cases). The overall rate for men in the EU/EEA was 9.2 per 100 000 population (Table 2) and for women, 2.6 per 100 000 population (Table 3). The overall male-to-female ratio was 3.3. The ratio was highest in Slovenia (15.0), Hungary (10.6), Croatia (9.2), the Czech Republic (9.1), and Malta (9.0) (Figure 1.1). The predominant mode of transmission in these countries was sex between men. Men had higher age-specific rates than women in all age groups, except among persons under 15 years, where age-specific rates were similar (Figure 1.2). The highest overall rate of new HIV diagnoses per 100 000 population was in the age group 25–29 years (14.6) with the rate in men and women peaking in this age group at 22.7 and 6.2, respectively. The 30–39-year-olds accounted for most HIV diagnoses overall (32%) and in all transmission groups: 42% of these cases were attributed to injecting drug use, 32% to sex between men and 32% to heterosexual transmission (Figure 1.3). Cases attributed to sex between men predominated in all age groups under 50 years while cases attributed to sex between men and women were predominant among those 50 years of age and over. Young people 15 to 24 years of age comprised 12% of the EU/EEA population and 11% of HIV diagnoses in 2014. Romania, Slovakia Cyprus, and Luxembourg reported more than 15% of their HIV diagnoses in this age group (Figure 1.4). In ten countries, this proportion was lower than 10%, and in two countries (Liechtenstein and Iceland), no cases were reported among 15–24-year-olds. Data on transmission mode provide information on the groups that are most affected by HIV in the EU/EEA (Table 12a, Tables 4–7): • Sex between men remains the predominant mode of HIV transmission reported in the EU/EEA, accounting for 42% (12 677) of all HIV diagnoses in 2014, and 53% of those where the route of transmission was known (Table 4, Figure 1.5). Among those with known route of HIV transmission, sex between men accounted for more than half of new diagnoses in 16 countries reporting more than one case (Austria, Croatia, Cyprus, the Czech Republic, Denmark, Germany, Greece, Hungary, Ireland, Malta, the Netherlands, Poland, Slovakia, Slovenia, Spain and the United Kingdom) (Figure 1.5). • Sex between men and women is the second most commonly reported mode of transmission in the EU/EEA, accounting for 41% (9 833) of HIV diagnoses where the route of transmission was known (Table 6, Figure 1.5). Heterosexual transmission is the most commonly reported known mode of transmission in 12 EU/EEA countries (Belgium, Estonia, Finland, France, Italy, Latvia, Lithuania, Luxembourg, Norway, Portugal, Romania and Sweden). More than one quarter (28%; 2 771) of newly diagnosed cases among heterosexuals originate from countries with generalised HIV epidemics. The highest proportions of these were observed in Germany (63%), Ireland (57%), the United Kingdom (48%) and France (46%) (Table 10). • Five per cent (1 244 cases) of HIV diagnoses with known route of HIV transmission were attributed to injecting drug use (Table 5, Figure 1.5). Injecting drug use was the probable route of transmission for one quarter or more of cases reported in Lithuania (33%), Latvia (31%), Estonia (28%) and Romania (25%) (Figure 1.5). • Of the remainder, 236 diagnoses (1%) were reported as mother-to-child transmission (Table 7); 41% (97) of those cases originated from countries with generalised HIV epidemics. Seventy-one diagnoses were reported to be due to transfusion of blood and its products, and 22 cases were hospital-acquired infections (Table 12a). The majority of these cases were born or thought to be acquired outside of the country in which the case was reported. • Transmission mode was reported as ‘unknown’ for 5 908 diagnoses (19.7%) with a wide variation between countries: less than 5% of diagnoses reported as ‘unknown’ in Bulgaria, the Czech Republic, Denmark, Luxembourg, Norway and Portugal and more than 60% reported as unknown in Iceland and Poland. In 2014, 29 EU/EEA countries provided information on the country of birth, country of nationality, or region of origin for 25 445 (85%) HIV diagnoses. In the EU/EEA, 9 579 diagnoses (37% of those with known information on region of origin) were made among people originating from outside of the reporting country. Of these, 4 139 diagnoses (16% of those with known information on region of origin), irrespective of transmission mode, were among people originating from countries with generalised HIV epidemics (Figure 1.6, Table 11). An additional 21% of new diagnoses with known region of origin (5 440 cases) were among people originating outside of the reporting country, but not from a generalised epidemic country. Countries with at least half of new HIV diagnoses among people originating from outside 1 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Figure 1.1: Male-to-female ratio in new HIV diagnoses, by country, EU/EEA, 2014 (n=29 912) Slovenia Hungary Croatia Czech Republic Malta Cyprus Slovakia Greece Netherlands Spain Poland Iceland Bulgaria Germany Italy Austria EU/EEA average Denmark Finland United Kingdom Norway Ireland Portugal Belgium Romania Latvia France Lithuania Estonia Luxembourg Sweden 0 4 8 12 16 Male-to-female ratio of the reporting country were Iceland (82%), Sweden (78%), Luxembourg (65%), Norway (60%), Ireland (60%), Belgium (53%), the United Kingdom (53%) and France (51%) (Figure 1.6). Information on CD4 cell count at the time of HIV diagnosis was provided by 23 countries (Table 14) for 18 411 HIV diagnoses (61%) in adults and adolescents. All countries providing these data were able to provide CD4 cell counts for more than 50% of their reported cases. Nearly half (47%) of all cases with a CD4 cell count available were diagnosed with a count of less than 350 cells per mm3, including 27% of cases with advanced HIV infection (CD4 <200 cells/mm3). The proportion of those diagnosed with a CD4 count lower than 350 cells per mm3 was higher than 50% in eight countries: Estonia (63%), Greece (51%), Italy (53%), Latvia (53%), Luxembourg (52%), Portugal (51%), Romania (58%) and Slovenia (62%). Among all cases diagnosed for whom a CD4 cell count was available, 20% (3 749) had a CD4 cell count of between 350 and 500 cells per mm3 and 33% (6 050) had a CD4 cell count of 500 cells or more per mm3. When analysing CD4 cell count by transmission mode, the highest proportion of people presenting at a later stage of HIV infection (CD4 <350 cells/mm3) was observed among people who acquired HIV through injecting drug use (61%) (Figure 1.7; Table 14). The lowest proportion with CD4 counts lower than 350 cells per mm3 was observed among men who acquired HIV through sex 2 with another man (37%). Twelve countries reported that half or more of the cases acquired through injecting drug use had a CD4 cell count lower than 350 cells per mm3 at diagnosis; four countries reported that more than half of new diagnoses among MSM had a CD4 cell count of less than 350 cells per mm3 at diagnosis (Table 14). The proportion of cases diagnosed at or below 350 CD4 cells per mm3 increased with age, and 61% of people aged 50 or older were diagnosed with HIV at or below 350 cells per mm3 (data not shown). Higher proportions of migrants from sub-Saharan Africa (57%) and South and Southeast Asia (57%) had CD4 counts of less than 350 cells per mm3 at diagnosis than non-migrants (46%) and other migrant groups (Figure 1.8). 1.2 Trends in HIV diagnoses The trend of reported HIV diagnoses for the period 2005– 2014 remains relatively stable, although the overall rate of HIV diagnoses per 100 000 population fluctuated between 6.6 and 6.9 until 2012 and has slightly declined thereafter to 6.4 per 100 000 population (32 605 cases when adjusted for reporting delay; see Annex 1 for methods; Annex 6 for results). Moreover, in the previous HIV/ AIDS surveillance report [1], 29 157 HIV diagnoses were reported for 2013, but after additional data collections included some historical data updates, this number has increased by more than 3 000 cases and may still HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT missing. Data from Spain and Italy were also excluded because coverage by the surveillance system was not constant and increased over this time period. Data on transmission mode from the countries consistently reporting indicate the following (Table 8a, Figures 1.9 and 1.10): increase further in similar updates over the coming one to two years. Over the past decade, trends at national level have varied widely. Since 2005, rates of HIV diagnoses have more than doubled in Bulgaria, the Czech Republic, Hungary, Malta and Slovakia and have increased by more than 50% in Poland. Rates of new HIV diagnoses decreased in 11 countries between 2005 and 2014, with decreases of more than 25% observed in Austria, Estonia, France, the Netherlands, Portugal and the United Kingdom (Table 1). Reporting delay affects some countries more than others and, thus, decreases in the rates of new HIV diagnoses may be overestimated. • The number of HIV diagnoses reported among MSM increased from 7 451 cases in 2005 to 9 110 cases in 2014, with a peak of 9 726 cases in 2013. The proportion of all HIV diagnoses attributed to sex between men increased over the period from 30% of cases in 2005 to 42% of cases in 2014. Between 2005 and 2014, increases were observed in all but six EU/ EEA countries (Table 4). Cases attributed to MSM increased over the period both among men born outside of the country of report and among native cases (Figure 1.10). Since 2005, 29 EU/EEA countries have consistently reported data on transmission mode. Data from Estonia and Poland were not included in this analysis because more than 50% of their data on transmission mode was Figure 1.2: Age- and gender-specific rates of new HIV diagnoses per 100 000 population, EU/EEA, 2014 (n=29 923) 25 Women Cases per 100 000 population Men 20 15 10 5 0 < 15 15-19 20-24 25-29 30-39 40-49 50+ Age category (years) Figure 1.3: Number of new HIV diagnoses by age group and transmission mode, EU/EEA, 2014 (n=23 747) 5000 Sex between men 4000 Injecting drug use Number of cases Heterosexual contact 3000 2000 1000 0 15-19 20-24 25-29 30-39 40-49 50+ Age category (years) Data for people <15 years old, other/unknown transmission, mother-to-child transmission, transfusion-related transmission, and nosocomial transmission not shown. 3 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Figure 1.4: Percentage of new HIV diagnoses in people between 15 and 24 years old, by country, EU/EEA, 2014 (n=29 992) Romania Slovakia Cyprus Luxembourg Hungary Bulgaria Czech Republic Croatia Poland Spain Portugal Ireland United Kingdom Germany EU/EEA Norway Greece Austria Denmark Malta Latvia Netherlands France Belgium Italy Sweden Estonia Lithuania Finland Slovenia Liechtenstein Iceland 0 5 10 15 20 25 Percentage Figure 1.5: Percentage of new HIV diagnoses with known mode of transmission, by transmission route and country, EU/EEA, 2014 (n=24 083) Sex between men Hungary Croatia Slovenia Czech Republic Cyprus Slovakia Malta Netherlands Germany Poland Spain Greece United Kingdom Ireland Denmark EU/EEA Austria Italy Belgium Norway France Bulgaria Finland Sweden Portugal Luxembourg Romania Latvia Lithuania Estonia Heterosexual contact Injecting drug use Other 0 20 40 60 80 100 Percentage Unknown route of transmission is excluded from proportions presented here. One HIV case reported in Liechtenstein in 2014 was attributed to sex between men and one case reported in Iceland in 2014 was attributed to injecting drug use. 4 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Figure 1.6: Percentage of new HIV diagnoses among migrants out of all reported cases with known information on region of origin, by country of report, EU/EEA, 2014 (n=25 525) New diagnoses among people originating from countries with generalised HIV epidemics Iceland Sweden Luxembourg Norway Ireland Belgium United kingdom France Malta Denmark Austria Finlad EU/EEA Cyprus Germany Netherlands Spain Portugal Italy Czech Republic Greece Slovenia Bulgaria Lithuania Slovakia Croatia Estonia Latvia New diagnoses among people originating from other countries 0 20 40 60 80 100 Percentage One or no cases were reported in 2014 among people born abroad by Hungary, Liechtenstein, Poland and Romania. Figure 1.7: New HIV diagnoses, by CD4 cell count per mm3 at diagnosis and transmission mode, EU/EEA, 2014 <200 cells/mm3 n = 8857 Transmission mode Sex between men 200 to <350 cells/mm3 350 to <500 cells/mm3 ≥500 cells/mm3 Heterosexual n = 7122 Injecting drug use n = 827 0 20 40 60 80 100 Percentage 5 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Region of origin Figure 1.8: New HIV diagnoses, by CD4 cell count per mm3 at diagnosis and region of origin of the case diagnosed, EU/EEA, 2014 Western Europe n =819 Central and Eastern Europe n =992 <200 cells/mm3 200 to <350 cells/mm3 350 to <500 cells/mm3 ≥500 cells/mm3 n =1182 Latin America and Caribbean n =11268 Non-migrants (native) n =430 South and Southeast Asia n =2698 Sub-Saharan Africa 0 20 40 60 80 100 Percentage People diagnosed with other or unknown region of origin are not presented here • The number of heterosexually acquired cases decreased from 11 912 in 2005 to 7 110 in 2014, with a steadily decreasing trend. The proportion of all HIV diagnoses attributed to sex between men and women decreased from 48% of cases in 2005 to 33% in 2014. The number of cases among women and among foreign-born heterosexuals decreased between 2005 and 2014 more than cases among men and nonforeign-born people (Figures 1.9 and 1.10). This was mainly due to a 52% decrease among cases originating from countries with generalised HIV epidemics (7 380 in 2005, 3 567 in 2014). • The number of HIV diagnoses reported among people who inject drugs has declined since 2005 (from 1 589 cases to 884 cases) in both foreign-born and non-foreign-born groups (Figure 1.10). A temporary increase in overall numbers for the EU/EEA was observed in 2011 and 2012 due to localised outbreaks in Greece and Romania, but reported cases in 2014 show a continued downward trend (Table 5). • The number of diagnoses reported to be due to HIV transmitted from mother to child decreased from 288 in 2005 to 215 in 2014. • The number of HIV diagnoses reported to be due to nosocomial infection has remained stable over this period, with 24 cases in 2005 and 21 in 2014. The number of cases reported to be due to transfusion of blood and its products has decreased from 122 in 2005 to 61 cases in 2014. The majority of these cases originate from outside of the reporting countries. • The number of cases reported to have an unknown mode of transmission has increased from 3 207 in 2005 to 4 177 cases in 2014. This increase is an underestimate as some countries reporting higher rates of incomplete data on transmission mode were excluded from the analysis. • Reporting delays differ significantly between transmission categories for some countries. When standardised adjustments for reporting delay are made, these increase the number of reported HIV cases in all transmission categories by between 8% and 19%, depending on the category. Figure 1.9 shows the adjusted trends. The median CD4 count at diagnosis improved over time among people with sex between men as the reported route of HIV acquisition as well as among those with heterosexual contact as the route of transmission (Figure 1.11). The median CD4 cell count at diagnosis among people that acquired HIV through injecting drug use fluctuated during the period and did not improve substantially over time. 1.3 AIDS cases, morbidity and mortality For 2014, 4 020 diagnoses of AIDS were reported by 30 EU/EEA countriesi, resulting in a rate of 0.8 cases per 100 000 population (Table 15). The highest rates were reported by Latvia (8.5, 171 cases) and Portugal (2.4, 249 cases). In the EU/EEA during the last decade, the rate of reported AIDS cases has halved from the 2.0 per 100 000 (9 203 cases) reported in 2005. This decline is noted in all transmission groups but appears greatest among cases attributed to heterosexual contact and injecting drug use (Figure 1.12). Despite the general EU/ EEA-wide decline, since 2005 an increase in the rate of AIDS diagnoses has been reported in Bulgaria, the Czech Republic, Greece, Hungary, Latvia, Lithuania, Malta, Norway and Slovenia. In the 20 EU/EEA countries where it was possible to fully link HIV and AIDS cases in 2014, 69% of AIDS diagnoses i All EU/EEA countries except Sweden. 6 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT occurred at the same time as, or within 90 days of, the HIV diagnosis. This ranged from 100% of AIDS cases reported (Cyprus, Denmark, Norway and Slovakia) to around 26% of new AIDS diagnoses in Latvia (Figure 1.13). diagnosed with AIDS. Overall, 1 131 individuals with AIDS were reported to have died during 2014 (Table 25). This figure has been consistently decreasing since 2004 when 3 094 deaths were reported among the same 28 countries reporting deaths in 2014, although delays in reporting affect the latest figures. From the beginning of the HIV epidemic to the end of 2014, a cumulative total of 344 265 individuals have been diagnosed with AIDS in the EU/EEA (Table 15). The cumulative total of cases reported as known to have died by the end of 2014 was 185 572 (Table 25). In the EU/EEA, the most common AIDS-indicative diseases diagnosed in 2014 were Pneumocystis pneumonia (22%), pulmonary and/or extra-pulmonary tuberculosis (14%), oesophageal candidiasis (10%), and wasting syndrome due to HIV (9%) (Table 24). Twenty-eight EU/EEA countries (all but Finland, Italy and Sweden) reported data on deaths of individuals Figure 1.9: New HIV diagnoses, by transmission mode and year of diagnosis, adjusted for reporting delay, EU/EEA, 2005-2014 12000 Sex between men Heterosexual contact (women) Number of cases 10000 Heterosexual contact (men) Injecting drug use 8000 Mother-to-child transmission Other/undetermined 6000 4000 2000 0 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Year of diagnosis HIV diagnoses reported by Estonia and Poland excluded due to incomplete reporting on transmission mode during some years of the period; diagnoses reported by Italy and Spain excluded due to increasing national coverage during the period Figure 1.10: New HIV diagnoses, by transmission and migration status, EU/EEA, 2005-2014 9000 Heterosexual contact (native) 8000 Heterosexual contact (foreign-born) Sex between men (native) Number of cases 7000 Sex between men (foreign-born) 6000 Injecting drug use (native) 5000 Injecting drug use (foreign-born) 4000 3000 2000 1000 0 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Year of diagnosis HIV diagnoses reported by Estonia and Poland excluded due to incomplete reporting on transmission mode during some years of the period; diagnoses reported by Italy and Spain excluded due to increasing national coverage during the period 7 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT CD4 cell count/mm3 at diagnosis Figure 1.11: Median CD4 cell count per mm3 at HIV diagnosis, by transmission group, EU/EEA, 2005-2014 500 Sex between men 450 Injecting drug use 400 Heterosexual contact 350 300 250 200 150 100 50 0 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Year of diagnosis Excludes countries with >60% incomplete data on CD4 cell count during any year over the period (Belgium, Bulgaria, Croatia, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Latvia, Lithuania, Malta, Norway, Poland, Portugal, Slovakia, Sweden) Figure 1.12: AIDS diagnoses, by transmission mode, EU/EEA, 2005-2014 (logarithmic scale) 10000 Sex between men Injecting drug use Number of cases Heterosexual contact Other/undetermined 1000 100 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Year of diagnosis Data from Sweden excluded due to inconsistent reporting during the period 1.4 Conclusions The 2014 HIV surveillance data suggest that the epidemic in EU/EEA countries persists, with little fluctuation in the rate of diagnoses per 100 000 population over the last decade. While the 2014 rate of 5.9 per 100 000 population is lower than previous years, it is expected to increase in future reporting cycles due to reporting delay which is common for HIV generally, and in some countries in the EU/EEA in particular. Despite the stable trend of HIV in the region, these data provide evidence of important changes in the 8 epidemiology of HIV during the past decade in EU/EEA countries. There has been a sustained increase in HIV diagnoses among both native and foreign-born MSM. MSM account for the largest number of new HIV diagnoses and are the only population in the EU/EEA where HIV cases continue to increase at an alarming rate. During the past decade, HIV increases among MSM were observed in all but six EU/EEA countries, and substantial increases were seen in countries with overall low rates of HIV such as Bulgaria, Croatia, Cyprus, the Czech Republic, Lithuania, Hungary, Malta, Romania and Slovakia. While some of these increases could be due to decreased stigmatisation resulting in reducing HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Figure 1.13: Percentage of AIDS diagnoses made in 2014 which occurred within 90 days of HIV diagnosis, EU/EEA, 2014 (n= 2 381) Slovenia Norway Denmark Cyprus Bulgaria Ireland Hungary Czech Republic Slovakia United Kingdom Poland Netherlands EU/EEA Portugal Romania Greece Luxembourg France Belgium Austria Latvia 0 20 40 60 80 100 Percentage In countries not listed, it was not possible to fully link HIV and AIDS diagnoses underreporting of sex between men as a transmission mode over time, in many countries the data indicates a pressing need to significantly scale up more effective multi-component prevention programmes for this at-risk population [2]. There has been a substantial decrease in the number of HIV infections transmitted through sex between men and women during the past decade. However, heterosexual transmission still remains the second most common mode of HIV transmission in the EU/EEA and is the most common transmission mode in some countries. Part of the decline in heterosexual cases is the result of the 52% decline (since 2005) in the number of heterosexually acquired cases in persons originating from countries with generalised HIV epidemics. However, cases among non-migrant heterosexuals have also decreased. Further investigation is required to understand whether the trends in decreased HIV diagnoses are mainly driven by decreasing incidence of HIV in these populations, increased use of ART, decreased testing, migration trends, or a combination of factors. In 2014, migrants, (or persons originating from outside of the reporting country), constituted a considerable proportion (37%) of new HIV diagnoses in the EU/EEA. There is evidence that a proportion of migrants, even those originating from HIV-endemic areas, acquire HIV after arrival in the EU/EEA [3-5] indicating the need for targeted interventions directed at this vulnerable population. Transmission among people who inject drugs is declining and remains at a low level in most countries in the EU/EEA. However, sudden increases were observed in recent years in Romania and Greece, countries with previously very low levels of HIV among people who inject drugs [6]. This illustrates the importance of maintaining adequate coverage of harm reduction services and that patterns can change quickly in this at-risk group, in the absence of effective prevention delivered at scale [7]. Although small, the continued numbers of cases infected through mother-to-child transmission indicate that greater efforts are needed to address these entirely preventable cases still occurring in some EU/EEA countries. Despite the clear evidence of the benefits of early introduction of antiretroviral treatment for the health of the HIV-positive individual [8, 9], many persons continue to be diagnosed with HIV at an advanced stage of illness. In addition to the clinical and personal benefits to the individual diagnosed, early diagnosis and treatment can also benefit sexual and injecting partners by inhibiting 9 HIV/AIDS surveillance in Europe 2014 onward HIV transmission. Nearly half of people (47%) diagnosed have a CD4 cell count of less than 350 cells per mm3 at diagnosis, including 27% of cases with advanced HIV infection (CD4 <200 cells/mm3). Furthermore, while AIDS cases are declining in the EU/EEA, 69% of the AIDS cases reported in 2014 were diagnosed at the same time or shortly after being diagnosed with HIV. This suggests problems with access to, and uptake of, HIV testing and counselling by those most at risk in many countries. The changes in the epidemiology of HIV infections observed in the EU/EEA over the last decade indicate that some progress has been achieved, particularly with regard to reduced infections attributed to heterosexual transmission and injecting drug use. However, these epidemiological trends also indicate that it is crucial to sustain evidence-based HIV prevention interventions that are tailored to the local epidemiological context and targeted at those most at risk. Programmes on the prevention and control of HIV infection adapted appropriately to key populations and maintained to scale remain important in EU/EEA countries. For most EU/EEA countries this means a strong focus on MSM, including foreign-born men who have sex with men. Other migrants, both those from high-endemic countries and other countries, are also a key population that needs specific prevention and control efforts in the majority of EU/EEA countries. Given the increasing evidence of post-migration HIV acquisition, it is important that migrant-sensitive services for prevention and HIV testing, combined with policies which promote and ensure linkage to, and access to, care are delivered in all countries across the EU/EEA. Finally, harm reduction programmes among people who inject drugs and their sexual partners are crucial and should be maintained and scaled up where service coverage is low. References 1 European Centre for Disease Prevention and Control/WHO Regional Office for Europe. HIV/AIDS surveillance in Europe 2013. Stockholm: ECDC; 2014. Available at: http://ecdc.europa.eu/en/publications/ Publications/hiv-aids-surveillance-report-Europe-2013.pdf 2 European Centre for Disease Prevention and Control. HIV and STI prevention among men who have sex with men. ECDC Guidance. Stockholm: ECDC: 2014. Available at: http://ecdc.europa.eu/en/ publications/Publications/hiv-sti-prevention-among-men-whohave-sex-with-men-guidance.pdf 3 Rice BD, Elford J, Yin Z, Delpech VC. A new method to assign country of HIV infection among heterosexuals born abroad and diagnosed with HIV. AIDS 2012; 26(15):1961-1966. 4 Fakoya I, Alvarez-del Arco D, Woode-Owusu M, Monge S, RiveroMontesdeoca Y, Delpech V, et al. A systematic review of postmigration acquisition of HIV among migrants from countries with generalised HIV epidemics living in Europe: implications for effectively managing HIV prevention programmes and policy. BMC Public Health. 2015; 15: 561. Available at: http://www.biomedcentral.com/ content/pdf/s12889-015-1852-9.pdf 5 Alvarez-del Arco D, Fakoya I, Monge S, Gennotte AF, Touloumi G, Zuure F, et al; aMASE. HIV Acquisition among migrants living in Europe: Results from aMASE (Advancing Migrant Access to Health Services in Europe). Paper presented at: European AIDS Clinical Society Conference. 15th European AIDS Conference; 2015 October 21-24; Barcelona, Spain. 6 Hedrich D, Kalamara E, Sfetcu O, Pharris A, Noor A, Wiessing L, et al. Human immunodeficiency virus among people who inject drugs: Is risk increasing in Europe?. Euro Surveill. 2013;18(48):pii=20648. Available online: http://www.eurosurveillance.org/ViewArticle. aspx?ArticleId=20648 7 European Centre for Disease Prevention and Control/European Monitoring Centre for Drugs and Drug Addiction. Prevention of infections among people who inject drugs. Stockholm: ECDC, 2011. Available at: http://ecdc.europa.eu/en/publications/ Publications/111012_Guidance_Infectious_diseases_IDU_brief.pdf 10 SURVEILLANCE REPORT 8 INSIGHT START Study Group. Initiation of antiretrovial therapy in early asymptomatic HIV infection. N Engl J Med. 2015:373(9):795-807. 9 World Health Organization. Guideline on when to start antiretroviral therapy and on pre-exposure prophylaxis for HIV. Geneva: WHO; 2015. Available at: http://apps.who.int/iris/bitstr eam/10665/186275/1/9789241509565_eng.pdf SURVEILLANCE REPORT HIV/AIDS surveillance in Europe 2014 2 HIV and AIDS in the WHO European Region 2.1 HIV and AIDS diagnoses in the WHO European Region HIV diagnoses With inclusion of 142 197 HIV infections newly diagnosed in 50 of the 53 countries of the WHO European Region in 2014i, the cumulative number of people diagnosed with HIV in the Region since reporting began in the 1980s increased to 1 840 136, including 995 175 people officially reported to the joint ECDC and WHO Regional Office for Europe surveillance system (Figure B) and 907 607 diagnosed in Russiaii [1]. The 142 197 people newly diagnosed in 2014 corresponded to a rate of 16.4 per 100 000 population (Table A). This number includes 56 945 newly diagnosed infections officially reported to ECDC/WHO Regional Office for Europe by 49 countriesiii and 85 252 new diagnoses from Russia [1]. The cited data for Russia were published by the Federal Scientific and Methodological Centre for Prevention and Control of AIDS and allowed inclusion of Russian data into HIV annual and cumulative regional totals and rates, quotation of country-specific annual and cumulative HIV totals and rates and new HIV diagnoses by transmission mode, as well as cumulative total AIDS diagnoses. All other regional HIV figures and all 2014 AIDS data presented in this report are based on data from the 49 countries reporting to ECDC/WHO. Seventy-seven per cent of people diagnosed with HIV in the 50 countries in 2014 were diagnosed in the East (109 921), 19% in the West (27 325) and 3% in the Centre of the Region (4 950) (Table A) (see Annex 1, Figure A1 for grouping of countries). The rate was also highest in the East (43.2 per 100 000 population), almost seven times higher than in the West (6.4 per 100 000) and sixteen times higher than in the Centre (2.6 per 100 000) (Table A). In the 49 countries reporting to ECDC/WHO, the 56 945 new diagnoses resulted in a rate of 7.9 per 100 000 population (not adjusted for reporting delayiv ). In the 49 countries, 43% of people newly diagnosed (24 669) were reported in the East with a rate of 22.3 per 100 000, 48% in the West and 9% in the Centre. For men, the rate for the Region was 11.1 per 100 000 population (Table 2) and for women, 4.7 per 100 000 population (Table 3). i No data from Bosnia and Herzegovina, Turkmenistan or Uzbekistan. One case from Liechtenstein is also included in the total number of newly diagnosed HIV infections presented in this report but, since Liechtenstein is not a Member State of the WHO European Region, data for Liechtenstein are not included in the totals for the West, Centre and East of the WHO European Region. ii Minus the 62 581 cases officially reported to ECDC/WHO by Russia in 2010. Rates of newly diagnosed HIV infections varied widely across countries in the WHO European Region for 2014. In Russia the rate was highest at 58.4 per 100 000 population [1]. Among reporting countries, the highest rates were reported by Ukraine (36.9)v, Estonia (22.1), Moldova (20.4), Belarus (19.1), Latvia (17.3), Kazakhstan (13.5), Georgia (13.3), Luxembourg (12.6), Tajikistan (11.9) and Kyrgyzstan (11.0) and the lowest were reported by the former Yugoslav Republic of Macedonia (1.4), Serbia (1.4), Slovakia (1.6), Croatia (2.2), the Czech Republic (2.2), Turkey vi (2.3) and Slovenia (2.4) (Table 1). Monaco reported zero cases. Among reporting countries, the majority of people newly diagnosed (36%) were in the age group 30–39 years, while 10% were young people aged 15–24 years. The male-to-female ratio was 2.2, lowest in the East (1.4), higher in the West (3.3) and highest in the Centre (4.4) (Table A). At country level, the highest male-tofemale ratios were observed in Slovenia (15.0), Hungary (10.6), Croatia (9.2), the Czech Republic (9.1) and Malta (9.0) and the lowest in Moldova (1.2), Kazakhstan (1.3), Kyrgyzstan (1.3), Tajikistan (1.3), Ukraine (1.3), Belarus (1.4) and Sweden (1.4) (Figures 1.1, 2.5, 2.12). Data on transmission mode provide information about risk exposure among people newly diagnosed with HIV in 2014 and indicate that (Table A, Tables 4–7): • Forty-seven per cent of people newly diagnosed were infected through heterosexual contact (26 664) (Table 6). Among people reported as infected through heterosexual contact, 13% originated from countries with generalised epidemics (data not shown). • Twenty-four per cent of people newly diagnosed were infected through sex between men (13 926) (Table 4). • Fourteen per cent were infected through injecting drug use (7 998) (Table 5). • One per cent (550) was infected through mother-tochild transmission (Table 7) and 0.2% (124) through other transmission routes (nosocomial infection, transfusion or use of other blood products). Eighteen per cent of children infected through mother-to-child transmission originated from countries with generalised epidemics (data not shown). • Transmission mode was reported as unknown or missing for 13% (7 674 cases). Information about country of birth, country of nationality or region of origin was provided by 43 countries for 32 406 newly diagnosed infections (57% of all new iii No data from Bosnia and Herzegovina, Russia, Turkmenistan or Uzbekistan. v Excluding data from Crimea and Sevastopol city iv When adjusting the Regional rate for reporting delay it increases to 8.2 per 100 000 population (59 647 cases), see Annex 1 for methods and Annex 6 for results. vi HIV data for Turkey do not include persons diagnosed with AIDS at the time of HIV diagnoses and are therefore not directly comparable with data for other countries. 11 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Figure 2.1: New HIV diagnoses, by CD4 cell count per mm3 at diagnosis and transmission mode, WHO European Region, 2014 (n=19 886) <200 cells/mm3 n = 9343 Sex between men 200 to <350 cells/mm3 350 to <500 cells/mm3 Transmission mode >500 cells/mm3 Heterosexual n = 9215 Injecting drug use n = 1328 0 20 40 60 80 100 Percentage Figure 2.2a: Rates of new HIV diagnoses, by year of diagnosis, WHO European Region*, 2005-2014 (including Russia) 50 West Cases per 100 000 population Centre East 40 WHO European Region 30 20 10 0 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Year of diagnosis * In 50 countries (data from Bosnia and Herzegovina, Turkmenistan and Uzbekistan excluded due to inconsistent reporting during the period). Figure 2.2b: Rates of new HIV diagnoses, by year of diagnosis, WHO European Region*, 2005-2014 (excluding Russia) 25 West Cases per 100 000 population Centre East 20 WHO European Region 15 10 5 0 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Year of diagnosis * In 49 countries (data from Bosnia and Herzegovina, Russia, Turkmenistan and Uzbekistan excluded due to inconsistent reporting during the period). 12 SURVEILLANCE REPORT diagnoses) (Table 11). 31% of these people (10 157) originated from outside of the reporting country, including 22% (7 174) who originated from outside the WHO European Region and 9% (2 983) from a European country other than the country of report. 13% originated from countries with generalised HIV epidemics. Information about probable country of infection was reported by 36 countries for 18 067 newly diagnosed infections (covering 32% of all new diagnoses). Among these people, 22% (3910 new diagnoses) were acquired abroad, among whom 38% were reported as infected in sub-Saharan Africa, 24% in central and eastern Europe, 15% in western Europe and 13% in south and south-east Asia (Table 13). In 2014, 34 countries provided information about CD4 cell count at the time of HIV diagnosis for 21 628 people over 14 years old (covering 38% of new diagnoses) (Table 14). Close to half (48%) of these people were late presenters with CD4 cell counts below 350 per mm3 at the time of HIV diagnosis, including 28% with advanced HIV infection (CD4 <200/mm3). 20% had a CD4 cell count of between 350 and 500 cells per mm3 and 32% had a CD4 cell count of 500 or more per mm3 (data not shown). The percentage of people diagnosed with a CD4 count of less than 350 per mm3 was higher than 50% in sixteen countries (8 East, 4 Centre, 4 West). The percentage of late presenters varied across transmission categories and was highest for people infected through injecting drug use (64%), lower for people infected through heterosexual contact (56%) and lowest for men infected through sex with men (37%) (Figure 2.1). The percentage of people diagnosed at or below 350 CD4 cells per mm3 increased with age, and 61% of people aged 50 or older were diagnosed with HIV at or below 350 cells per mm3. Trends in HIV diagnoses The rate of newly diagnosed HIV infections increased by 59% for the period 2005–2014, from 10.3 per 100 000 population in 2005 (80 652 cases) to 16.4 per 100 000 population in 2014 (142 197 cases) in 50 countries with consistent datai. The increase is mainly driven by an upward trend in the East where the rate increased by 115%, from 20.1 in 2005 (51 058 cases) to 43.2 in 2014 (109 921 cases) (Figure 2.2a). In the 49 countries that reported to ECDC and WHO, the regional rate increased by 11%, from 7.1 in 2005 (45 251 cases) to 7.9 in 2014 (56 945 cases) (not adjusted for reporting delayii). In the East, the rate increased by 59%, from 14.1 in 2005 (15 657 cases) to 22.3 in 2014 (24 669 cases); in the Centre, by 117%, the largest relative increase across the three geographical areas from 1.2 (2 165 cases) to 2.6 (4 950 cases) whereas in the West, the rate decreased by 20%, from 8.0 i Data from Bosnia and Herzegovina, San Marino, Turkmenistan and Uzbekistan not included. ii When adjusting the 2014 rate for the WHO European Region (49 countries) for reporting delay it increases to 8.2 per 100 000 population (59 630 cases) and the trend for the period 2005–2014 changes from an 11% increase to a 16% increase (see Annex 1 for methods and Annex 6 for results). HIV/AIDS surveillance in Europe 2014 (27 425 cases) to 6.4 (27 325 cases) (not adjusted for reporting delay, see Chapter 2.4) (Figure 2.2b). A total of 16 748 716 HIV tests performed for diagnostic purposes were reported by 26 countries for 2014. Countries in the East and West tended to report higher testing rates than countries in the Centre (Table 27). In 24 countries with data for both 2005 and 2014, the total number of tests increased by 35%, from 12 263 189 to 16 558 233. The number of tests increased by 10% or more in 18 countries and decreased by 10% or more in five countries. Some 44 countries have consistently reported data on transmission mode for the period 2005–2014 (Table 8, Figure 2.3). Data from Estonia, Poland and Turkey were excluded because more than 50% of their data on transmission mode was missing; data from Spain and Italy were excluded because coverage of the national surveillance system increased over this time period; and data from Bosnia and Herzegovina, Russia, Turkmenistan and Uzbekistan were not reported. Data on transmission mode from the countries with consistent data indicate the following: • The number of new diagnoses of people infected through heterosexual contact increased by 28% from 18 392 in 2005 to 23 456 in 2014 (Table 6, inconsistently reporting countries excluded). • The number of new diagnoses of people infected through sex between men increased by 28% from 7 859 in 2005 to 10 086 in 2014 (Table 4, inconsistently reporting countries excluded). • The number of new diagnoses of people infected through injecting drug use decreased by 22% from 9 738 in 2005 to 7 628 in 2014 with a peak of 11 427 in 2007 (Table 5, inconsistently reporting countries excluded). • The number of new diagnoses of children infected through mother-to-child transmission decreased by 11% from 570 in 2005 to 507 in 2014 with a peak of 643 in 2007 (Table 7, inconsistently reporting countries excluded). • Of the new diagnoses of people infected by other means, nosocomial infections increased by 29% from 28 in 2005 to 36 in 2014 (with peaks of 117 in 2007 and 106 in 2012), and infections due to transfusion of blood and its products decreased by 52% from 140 in 2005 to 67 in 2014. • The number of new diagnoses reported with unknown risk factors increased by 35% from 3 648 in 2005 to 4 934 in 2014. Analysing trends by region of origin, there was a 27% increase in new diagnoses among people originating from within the reporting country, whereas new diagnoses among non-natives decreased by 28%. Examining the trend among non-natives by region of origin revealed a 41% decrease among non-European migrants (people originating from a country outside the WHO European 13 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Figure 2.3: New HIV diagnoses, by transmission mode and year of diagnosis, WHO European Region, 2005-2014 30000 Heterosexual Sex between men Number of cases 25000 Injecting drug use Mother-to-child transmission 20000 Other/undetermined 15000 10000 5000 0 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Year of diagnosis Data from Bosnia and Herzegovina, Russia, Turkmenistan and Uzbekistan excluded due to inconsistent reporting during the period; data from Estonia, Poland and Turkey excluded due to incomplete reporting on transmission mode during the period; data from Italy and Spain excluded due to increasing coverage of national surveillance during the period. Cases per 100 000 population Figure 2.4: Rates of new AIDS diagnoses, by geographical area and year of diagnosis, WHO European Region, 2005-2014 12 West Centre 10 East WHO European Region 8 6 4 2 0 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Year of diagnosis Data from Bosnia and Herzegovina, Russia, San Marino, Sweden, Turkmenistan and Uzbekistan excluded due to inconsistent reporting during the period. Region) and a 48% increase among European migrants (i.e. people originating from a European country other than the country of report) (Figure C). The decrease among non-European migrants is mainly driven by a decline in people with sub-Saharan African origin while the increase in new diagnoses among European migrants is mainly driven by an increase among people originating from central and eastern Europe (data not shown). AIDS cases, morbidity and mortality Since the beginning of the epidemic, at least 487 087 people have been diagnosed with AIDS in the WHO European Region. This number includes 451 667 diagnoses officially reported to ECDC/WHO and 35 420 people 14 diagnosed with AIDS in Russia as of 31 December 2014 [1]. In 2014, 16 037 people were newly diagnosed with AIDS in 47 countries of the WHO European Regioni, which is a rate of 2.3 per 100 000 population (Table 15). 74% of people (11 890) were diagnosed in the East, 20% (3 214) in the West and 6% (932) in the Centre of the Region. The rate was also highest in the East (10.7 per 100 000 population), 13 times higher than in the West (0.8 per 100 000) and 21 times higher than in the Centre (0.5 per 100 000). i No data available from Bosnia and Herzegovina, Russia, San Marino, Sweden, Turkmenistan or Uzbekistan. HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Figure 2.5: Male-to-female ratio in all new HIV diagnoses and new diagnoses with heterosexual transmission, by country, East, 2014 Georgia Latvia Armenia 1.8 0.9 1.6 0.7 1.4 0.8 Belarus 1.4 1.1 Ukraine 1.3 0.8 Tajikistan 1.1 Kazakhstan 1.3 0.6 1.0 0.5 1.3 1.3 0.7 Moldova 0.0 1.7 1.1 East average Kyrgyzstan 1.8 1.4 Estonia Azerbaijan People infected through heterosexual contact 2.1 1.2 Lithuania All people newly diagnosed 2.6 1.1 1.0 1.2 1.5 2.0 2.5 3.0 Male-to-female ratio At country level the rate of new AIDS diagnoses varied widely, with the highest rates reported in Ukraine (23.0), Latvia (8.5), Georgia (6.6), Armenia (5.7), Moldova (5.7) and Belarus (5.0) and the lowest rates (0.3 or less) in Slovakia (0.1), Czech Republic (0.2), Turkey (0.2) i, Germany (0.3) and Poland (0.3). Andorra, Iceland and Monaco reported zero cases. Between 2005 and 2014, the rate of new AIDS diagnoses decreased by 4%, from 2.3 per 100 000 population (14 294 cases) to 2.2 per 100 000 (16 037 cases) in the 47 countries with consistent AIDS dataii (Figure 2.4). Because of reporting delays in some countries, this decrease may even out over the coming years. AIDS trends varied greatly across the three geographical areas. In the East, the rate increased by 143% from 4.4 in 2005 (4 926 cases) to 10.7 in 2014 (11 890 cases). In the Centre, the rate increased by 25% from 0.4 in 2005 (751 cases) to 0.5 in 2014 (932 cases) while in the West, the steady downward trend continued with a 69% decrease in the rate from 2.6 in 2005 (8 617 cases) to 0.8 in 2014 (3 214 cases). i AIDS data for Turkey only include people diagnosed with AIDS at the time of HIV diagnosis and are therefore not comparable with AIDS data from other countries. ii Data from Bosnia and Herzegovina, Russia, San Marino, Sweden, Turkmenistan and Uzbekistan excluded or not available. Information about deaths of people who had previously been diagnosed with AIDS (irrespective of the year of diagnosis) was provided by 45 countries in the WHO European Regioniii for 2014. In these 45 countries, 5 052 people with AIDS were reported to have died during 2014; a 12% decrease compared with the 5 725 deaths in 2005. Of the 5 052 deaths in 2014, 78% were reported from the East of the Region, 15% from the West and 7% from the Centre. These new figures bring the total number of reported deaths of people with AIDS from the beginning of reporting to 31 December 2014 to 263 727: 235 466 officially reported to ECDC/WHO and 28 261 in Russia as of December 2013iv [2]. 2.2 HIV and AIDS diagnoses in the East HIV diagnoses in the East In 2014, 109 921 people were newly diagnosed with HIV in 13 countriesv in the East of the WHO European Region, giving a rate of 43.2 per 100 000 population. This number includes 24 669 new diagnoses officially reported to iii No data from Bosnia and Herzegovina, Finland, Italy, Russia, San Marino, Sweden, Turkmenistan or Uzbekistan. iv Latest publicly available data. v No data from Turkmenistan and Uzbekistan. 15 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Figure 2.6: New HIV diagnoses, by age group and transmission mode, East, 2014 (n= 23 828) 15-19 n = 6872 Transmission mode Injecting drug use 20-24 25-29 30-39 Heterosexual contact n = 16424 Sex between men 40-49 50+ n = 532 0 20 40 60 80 100 Percentage No data from Russia, Turkmenistan or Uzbekistan. WHO/ECDC and 85 252 from Russia [1] and it is the highest number of people and the highest rate ever observed in the East. • Twenty-eight per cent of people newly diagnosed were infected through injecting drug use (6 872) (Table 5). For the 12 countries reporting to ECDC/WHO, the rate was 22.3 per 100 000 population. At country level, the highest rates for 2014 were observed in Russia (58.4 per 100 000 population) [1], Ukraine (36.9), Estonia (22.1), Moldova (20.4), Belarus (19.1) and Latvia (17.3); while the lowest rates were reported by Lithuania (4.8) and Azerbaijan (6.3). In 11 of 13 countries the rate for 2014 was higher than 10 per 100 000 population. • Two per cent were infected through sex between men (532) (Table 4). The majority of people newly diagnosed in the 12 reporting countries were in the age group 30–39 years (41%), while 9% were young people aged 15–24 years (Table A). The male-to-female ratio was 1.4, the lowest of the three geographical areas, translating into 42% of new diagnoses being in women in the East. The male-to-female ratio was highest in Georgia (2.6), Latvia (2.1) and Armenia (1.8) and lowest in Moldova (1.2), Kazakhstan (1.3), Kyrgyzstan (1.3), Tajikistan (1.3) and Ukraine (1.3) (Figure 2.5). Among people infected through heterosexual contact, the male-to-female ratio was higher than 1 (i.e. more men than women) in seven countries (Armenia, Belarus, Estonia, Georgia, Latvia, Moldova and Tajikistan) suggesting more men than women being newly infected through heterosexual contact. In the East of the Region, heterosexual contact and injecting drug use are the main modes of HIV transmission while few people are reported as infected through sex between men. For 2014, information about transmission mode was provided by 12 countries and indicates the following (Table A, Tables 4–7): • Sixty-six per cent of people newly diagnosed were infected through heterosexual contact (16 247) (Table 6). 16 • 1.2% (289) were infected through mother-to-child transmission (Table 7) and 0.1% (17) through other transmission routes (nosocomial infection, transfusion or use of other blood products). • Transmission mode was reported as unknown or missing for 3% of people newly diagnosed (712). In Russia, among people newly diagnosed with known mode of HIV transmissioni (about half of cases [2]), 57% were infected through injecting drug use, 40% through heterosexual transmission, 1% through sex between men and 0.1% through mother-to-child transmission [1]). The 30–39-year-olds accounted for most HIV diagnoses in all transmission groups, including 51% of people infected through injecting drug use, 38% of people infected through heterosexual contact and 34% of people infected through sex between men. People in the younger age groups tended to be infected through sex between men while people in the older age groups were more frequently infected through injecting drug use or heterosexual contact, with people aged 50 and older being twice as likely to be infected through heterosexual contact as through drug injecting or sex between men (Figure 2.6). In 2014, heterosexual contact remained the main reported transmission mode in all 12 countries in the East while transmission through injecting drug use accounted i This analysis approach differs from the rest of the report where cases with unknown transmission mode are shown separately and included in the denominator for percentage calculations. The percentages for Russia are therefore not directly comparable with those presented of other countries or groups of countries. HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Figure 2.7: New HIV diagnoses by country and transmission mode, East, 2014 (n= 24 338) Heterosexual contact Armenia Injecting drug use Azerbaijan Sex between men Mother-to-child transmission Belarus Other Estonia Unkown Georgia Kazakhstan Kyrgyzstan Latvia Lithuania Moldova Tajikistan Ukraine 0 20 40 60 80 100 Percentage for 30% or more of new diagnoses in four countries (Azerbaijan, Georgia, Kazakhstan and Ukraine) and less than 15% of new diagnoses in two countries (Armenia and Moldova) (Figure 2.12). Information on transmission mode was lacking for more than 10% of people newly diagnosed in five of the 12 countries (Estonia, Latvia, Lithuania, Moldova and Tajikistan). Eight countries provided information about CD4 cell count at the time of HIV diagnosis for 2 753 people over 14 years old (covering 11% of new diagnoses in the East and 60% of new diagnoses in the eight reporting countries) (Table 14). 58% of these people were late presenters with CD4 cell counts below 350 per mm3, including 33% with advanced HIV infection (CD4 <200/mm3). 20% had a CD4 cell count of between 350 and 500 cells per mm3 and 22% had a CD4 cell count of 500 or more per mm3. The percentage of people diagnosed with a CD4 count of less than 350/mm3 was higher than 50% in all countries: Kyrgyzstan (71%), Tajikistan (64%), Estonia (63%), Georgia (58%), Armenia (55%), Latvia (53%), Azerbaijan (52%) and Moldova (52%). The percentage of late presenters varied across transmission categories and was highest for people infected through injecting drug use (68%), lower for people infected through heterosexual contact (56%) and lowest for men infected through sex with men (44%) (Figure 2.8). In 2014, seven countries in the East provided information on the probable source of infection for the 2 653 people infected through heterosexual contact (Armenia, Azerbaijan, Estonia, Georgia, Kyrgyzstan, Moldova and Tajikistan) (Table 10). Among those people, the probable source of infection for 46% of cases (data not shown) was a heterosexual partner from a country without a generalised epidemic , sexual contact with a person who injects drugs was the source of infection for 5% of cases, and ‘other or unknown’ partner risk factors for 47% of cases. These data suggest that the increasing numbers of people reported as infected through heterosexual contact might be linked with periodical migration to neighbouring countries without a generalised epidemic. Nine countries provided information about the probable country of infection for 4 866 people newly diagnosed in 2014 (covering 20% of new diagnoses in the East) (Table 13). From that sample, 12% (578 new diagnoses) were acquired abroad; among whom 92% were infected in neighbouring countries of central and eastern Europe. This variable, if better reported, could provide key information about the extent to which people are becoming infected in their home country or during periods of being abroad. 17 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Figure 2.8: New HIV diagnoses, by CD4 cell count per mm3 at diagnosis and transmission mode, East, 2014 (n=2 609) <200 cells/mm3 n = 117 Transmission mode Sex between men 200 to <350 cells/mm3 350 to <500 cells/mm3 ≥500 cells/mm3 Heterosexual n = 1938 Injecting drug use n = 554 0 20 40 60 80 100 Percentage Trends in HIV diagnoses in the East The trend of newly diagnosed HIV infections continued to increase during the decade with a 115% increase in the rate of diagnoses per 100 000 population between 2005 and 2014, from 20.1 in 2005 (51 058 cases) to 43.2 in 2014 (109 921 cases) (Russia included) (Figure 2.1a). In the 12 officially reporting countries, the rate increased by 58% from 14.1 in 2005 (15 657 cases) to 22.3 in 2014 (24 669 cases) (Figure 2.1b). The number of women newly diagnosed increased by 74% between 2005 and 2014 in the 12 countries, from 5 903 to 10 298 and the number of men newly diagnosed increased by 49%, from 9 562 to 14 251 (Tables 2 and 3). Of the 12 countries with consistent data, 11 have reported increasing numbers and rates of new HIV diagnoses during the period 2005–2014. The rate of new diagnoses increased more than threefold in Armenia, Kyrgyzstan and Tajikistan and more than doubled in Azerbaijan, Belarus, Georgia and Kazakhstan. In Russia the number of people newly diagnosed more than doubled with a 141% increase from 35 401 in 2005 to 85 252 in 2014. In Ukraine, the rate of new diagnoses seems to have stabilised over the past four years with the rate in 2014 (36.9) remaining at a similar level as that for 2010 (36.4). In Estonia, the only country in the East where a decrease was observed over the decade, the rate of new diagnoses halved from 45.7 to 22.1 per 100 000 (Table 1). During the same period, the number of HIV tests doubled in the 12 countries with consistent data, from 3 545 291 in 2005 to 7 424 986 in 2014 (Table 27). Information about mode of transmission for the period 2005–2014 from the 11 countries with consistent datai indicates the following (Table 8b, Figure 2.9): in Azerbaijan, Kazakhstan and Kyrgyzstan it increased more than fivefold. • The number of new diagnoses of people infected through injecting drug use decreased by 17% from 8 203 in 2005 to 6 805 in 2014 following a peak in 2007–2010 (Table 5, inconsistently reporting countries excluded). In six countries, however, the number of new diagnoses has increased in comparison with 2005 (Azerbaijan, Belarus, Georgia, Kazakhstan, Kyrgyzstan and Tajikistan) although the numbers have decreased in comparison with more recent years (2008–2011) in all countries. • The number of new diagnoses of people infected through sex between men increased almost ten times from 57 in 2005 to 529 in 2014. (Table 4, inconsistently reporting countries excluded). • The number of children infected through mother-tochild transmission increased by 9% from 260 in 2005 to 284 in 2014. (Table 7, inconsistent reporting countries excluded). • The number of new diagnoses for which the mode of transmission was unknown increased by 16% from 568 in 2005 to 658 in 2014. On a logarithmic scale, allowing comparison of rates of change regardless of starting point, the very large relative increase in the rate of new diagnoses acquired through sex between men as compared with other transmission modes is clearly visible (Figure 2.9). AIDS cases, morbidity and mortality in the East • The number of new diagnoses of people infected through heterosexual contact increased by 171% from 5 935 in 2005 to 16 085 in 2014 (Table 6, inconsistently reporting countries excluded). In Armenia and Tajikistan the number increased tenfold or more and In 2014, 11 890 people were diagnosed with AIDS in the 12 countries in the Eastii that provided AIDS data, giving a rate of 10.7 per 100 000 population. The highest rates were reported in Ukraine (23.0), Latvia (8.5), Georgia (6.6), Armenia (5.7), Moldova (5.7) and Belarus (5.0) and the lowest rates in Lithuania (1.3), Estonia (1.4), Kazakhstan (1.4) and Kyrgyzstan (1.4) (Table 15). Since the beginning of reporting and up to 31 December 2014, i Data from Estonia, Russia and Uzbekistan not included. ii No data from Russia, Turkmenistan or Uzbekistan. 18 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Figure 2.9: New HIV diagnoses, by transmission mode and year of diagnosis, East, 2005-2014 Arithmetic scale 20000 Heterosexual contact Sex between men Injecting drug use Number of cases 15000 Mother-to-child transmission Other/undetermined 10000 5000 0 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Year of diagnosis Logarithmic scale 100000 Heterosexual contact Sex between men Number of cases 10000 Injecting drug use Mother-to-child transmission Other/undetermined 1000 100 10 1 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Year of diagnosis Data from Russia, Turkmenistan and Uzbekistan excluded due to inconsistent reporting during the period; data from Estonia excluded due to incomplete reporting on transmission mode during the period. 130 096 people in the East have been diagnosed with AIDS: 94 676 diagnoses officially reported to ECDC/WHO and 35 420 people diagnosed in Russia [1]. Between 2005 and 2014 the AIDS rate increased by 143%, from 4.4 cases per 100 000 population (4 926 cases) to 10.7 (11 890 cases) in the 12 countries (Figure 2.4). The number of new AIDS diagnoses increased in all countries in the East except Estonia, most noticeably in Tajikistan (a 40-fold increase), Azerbaijan (a 10-fold increase) and in Armenia, Kyrgyzstan, Lithuania and Moldova (3–4-fold increases). By mode of transmission, new AIDS diagnoses among people infected through heterosexual transmission increased sixfold while new diagnoses in men infected through sex with men, although much lower in absolute terms, increased almost as much (fivefold) in 2014 compared with 2005 (Figure 2.10). The most common AIDS-indicative diseases diagnosed in 2014 were pulmonary tuberculosis (24% of all disease events reported), wasting syndrome due to HIV (14%) and oesophageal candidiasis (13%) (Table 24). By transmission mode, pulmonary tuberculosis was the most common disease in all three groups, while wasting syndrome due to HIV, extrapulmonary tuberculosis and oesophageal candidiasis were distributed across categories as the second and third most common diseases (Figure 2.11). Mortality among people who ever had an AIDS diagnosis remains high in the East. Some 3 941 deaths were reported by the 12 countries for 2014, a 55% increase 19 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Figure 2.10: New AIDS diagnoses, by transmission mode and year of diagnosis, East, 2005-2014 Arithmetic scale 8000 Heterosexual contact 7000 Sex between men Injecting drug use Number of cases 6000 Mother-to-child transmission 5000 Other/undetermined 4000 3000 2000 1000 0 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Logarithmic scale 100000 Heterosexual contact Sex between men Number of cases 10000 Injecting drug use Mother-to-child transmission Other/undetermined 1000 100 10 1 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Year of diagnosis Data from Russia, Turkmenistan and Uzbekistan excluded due to inconsistent reporting during the period. IDU Hetero Figure 2.11: Distribution of the three most common AIDS-defining illnesses per transmission mode, East, 2014 240 Mycobacterium tuberculosis, pulmonary 92 Wasting syndrome due to HIV 58 Candidiasis, oesophageal 240 Mycobacterium tuberculosis, pulmonary 127 Mycobacterium tuberculosis, extrapulmonary 64 MSM Wasting syndrome due to HIV 6 Mycobacterium tuberculosis, pulmonary 5 Candidiasis, oesophageal 3 Mycobacterium tuberculosis, extrapulmonary 0 5 10 15 Percentage No data from Russia, Turkmenistan or Uzbekistan. Hetero: heterosexual transmission; IDU: injecting drug use; MSM: men having sex with men. 20 20 25 30 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Figure 2.12: Male-to-female ratio in new HIV diagnoses, by country, Centre, 2014 Slovenia Hungary Croatia Czech Republic Cyprus Slovakia Serbia Montenegro Poland Bulgaria Centre average Turkey Albania Romania 0 4 8 12 16 Male-to-female ratio The former Yugoslav Republic of Macedonia did not report any female cases in 2014. in comparison with the 2 544 deaths in 2005, although the number of deaths has begun to decline since 2012 (Table 25). The 2014 data bring the cumulative number of deaths in the East since the beginning of reporting to 70 846; 42 585 officially reported to WHO/ECDC and 28 261 in Russia [1]. 2.3 HIV and AIDS diagnoses in the Centre HIV diagnoses in the Centre The HIV epidemic in the Centre remains at a relatively low level although the number of new diagnoses is increasing in many countries, especially in people infected through sex between men. A total of 4 950 people were newly diagnosed with HIV in 2014 in 14 of the 15 countries in the Centre of the WHO European Region, igiving a rate of 2.6 per 100 000 population (Table 1). The highest rates were observed in Cyprus (6.5), Romania (4.0), Bulgaria (3.4) and Montenegro (3.2); and the lowest in the former Yugoslav Republic of Macedonia (1.4), Serbia (1.4) and Slovakia (1.6). The most affected age group in 2014 was the 30–39-yearolds with 34% of cases, whereas 15% were diagnosed in young people aged 15–24 years (Table A). The maleto-female ratio was 4.4, higher than in both the West and the East. The highest male-to-female ratios were observed in Slovenia (15.0), Hungary (10.6), Croatia (9.2) and the Czech Republic (9.1) (Figure 2.12). In the Centre, sex between men and heterosexual contact were the predominant transmission modes. For 2014, information on transmission mode was provided by 14 countries and indicates the following (Table A, Tables 4–7): • Twenty-eight per cent of people newly diagnosed were infected through sex between men (1 386) (Table 4). • Twenty-four per cent of people newly diagnosed were infected through heterosexual contact (1 205) (Table 6). i No data from Bosnia and Herzegovina for 2014 21 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT • Five per cent of people newly diagnosed were infected through injecting drug use (270). in 2005 to 878 in 2014 (Table 4, inconsistently reporting countries excluded). • One per cent was infected through mother-to-child transmission (50). • The number of new diagnoses in people infected through heterosexual transmission increased by 26% from 501 cases in 2005 to 632 cases in 2014 (Table 6, inconsistently reporting countries excluded). • Transmission mode was unknown for 41% of people newly diagnosed (2 026). In 2014, sex between men remained the predominant reported mode of transmission in ten countries: Bulgaria, Croatia, Cyprus, the Czech Republic, the former Yugoslav Republic of Macedonia, Hungary, Montenegro, Serbia, Slovakia and Slovenia; whereas heterosexual transmission was the main mode of transmission in Albania and Romania. In Poland and Turkey, transmission mode was unknown for more than 50% of new diagnoses making the assessment of main transmission mode uncertain. Transmission mode information was lacking for more than 10% of people newly diagnosed in nine of 14 countries (Figure 2.13). Nine countries provided information about CD4 cell count at HIV diagnosis for 1 596 people over 14 years old (covering 33% of new diagnoses in the Centre) (Table 14). 51% of these people were late presenters with CD4 cell counts below 350 per mm3 at HIV diagnosis, including 32% with advanced HIV infection (CD4 <200/mm3). 19% had a CD4 cell count of between 350 and 500 cells per mm3and 30% had a CD4 cell count of 500 or more per mm3. The percentage of people diagnosed with CD4 counts of less than 350/mm3 was higher than 50% in two countries: Albania (77%) and Serbia (67%). The percentage that were late presenters varied across transmission categories and was highest for people infected through injecting drug use (58%), lower for people infected through heterosexual contact (54%) and lowest for men infected through sex with men (39%) (Figure 2.14). Trends in HIV diagnoses in the Centre In the 14 countries in the Centre, the rate of new HIV diagnoses increased by 117% between 2005 and 2014, from 1.2 per 100 000 population in 2005 (2 165 cases) to 2.6 in 2014 (4 950 cases) (Figure 2.2). Rates increased in all countries and more than doubled in seven: Albania, Bulgaria, the Czech Republic, Hungary, Montenegro, Slovakia and Turkey. Reported data from six countries suggest a small increase in HIV testing, with a reported 18% increase in the number of tests performed in 2014 (3 163 703) compared with 2005 (2 677 179) in the eight countries with data for both years (Table 27). Information about mode of transmission for the period 2005–2014 in the 12 countries with consistent datai indicates the following (Table 8b, Figure 2.14): • The number of new diagnoses in people infected through sex between men more than tripled from 276 i Data from Bosnia and Herzegovina not reported, and data from Poland and Turkey not included because information on transmission mode was lacking for more than 50% of cases. 22 • The number of new diagnoses in people infected through injecting drug use increased sixfold from 35 in 2005 to 223 in 2014, mainly due to an outbreak in Romania that started in 2011 and decreased in 2014 (Table 5, inconsistently reporting countries excluded). • The number of new diagnoses in people infected through mother-to-child transmission decreased by 13%, from 30 children in 2005 to 26 in 2014 (Table 7, inconsistently reporting countries excluded). • The number of new diagnoses reported with unknown transmission mode increased by 3% from 308 in 2005 to 316 in 2014. AIDS cases, morbidity and mortality in the Centre A total of 932 people were diagnosed with AIDS in the 14 reporting countries in the Centre in 2014, corresponding to a rate of 0.5 per 100 000 population (Table 15). The highest rates were reported by Romania (1.9), Albania (1.7) and Montenegro (1.1). In the other countries, AIDS rates remained below 1.0 per 100 000 population. Between 2005 and 2014 the rate of new AIDS diagnoses increased by 25%, from 0.4 per 100 000 in 2005 (750 cases) to 0.5 per 100 000 in 2014 (932 cases) (Figure 2.4). At country level trends were heterogeneous. Of the nine countries reporting more than 20 AIDS cases in 2014, the rate increased in six (Albania, Bulgaria, the Czech Republic, Hungary, Romania and Turkey), decreased in two (Poland and Serbia) and remained stable in one (Croatia) (Table 15). By mode of transmission, new AIDS diagnoses increased most among men infected through sex between men (by 105%), second most in people infected through injecting drug use (by 72%) and third most in people infected through heterosexual contact (by 32%) in 2014 compared with 2005. Contrary to the distribution of transmission modes for new HIV diagnoses in the Centre (where sex between men predominates), the majority of new AIDS diagnoses were in people infected through heterosexual contact (Figure 2.16). The most common AIDS-indicative diseases diagnosed in 2014 were wasting syndrome due to HIV (18%), pulmonary tuberculosis (11%) and Pneumocystis pneumonia (10%) (Table 24). By transmission mode, the most common diseases for people infected through sex between men are Pneumocystis pneumonia, wasting syndrome due to HIV and oesophageal candidiasis; for people infected through injecting drug use, pulmonary tuberculosis, wasting syndrome due to HIV and extrapulmonary tuberculosis; and for heterosexuals, wasting syndrome due to HIV, pulmonary tuberculosis and oesophageal candidiasis (Figure 2.17). HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Figure 2.13: New HIV diagnoses by country and transmission mode, Centre, 2014 (n= 9 790) Sex between men Albania Heterosexual contact Turkey Injecting drug use Romania Other Poland Unkown Bulgaria Serbia Slovakia Hungary Montenegro Slovenia Cyprus Czech Republic Croatia Former Yugoslav Republic of Macedonia 0 20 40 60 80 100 Percentage Mortality among people diagnosed with AIDS remains low and stable in the Centre. Some 365 deaths were reported by the 14 countries for 2014, no change compared with the 366 people who died in 2005 (Table 25). 2.4 HIV and AIDS diagnoses in the West HIV diagnoses in the West The epidemiological pattern of HIV infection in the West largely mirrors that of the EU/EEA as described in Chapter 1. In 2014, 27 325 people were newly diagnosed with HIV in the West of the WHO European Region in the 23 countries giving a rate of 6.4 per 100 000 population (not adjusted for reporting delayi) (Table 1, Table A). Of newly diagnosed HIV infections in 2014, the majority (32%) were 30–39-year-olds, 11% were aged 15–24 years old and the male-to-female ratio was 3.3 (Table A). Sexual transmission between men remained the main transmission mode in 2014, followed by heterosexual transmission, together accounting for 78% of new diagnoses. Information about transmission mode indicates the following (Table A, Tables 4–7): i When adjusting the rate for the West for reporting delay it increases to 7.0 per 100 000 population (29 728 cases), see Annex 1 for methods and Annex 6 for results. • Forty-four per cent of people newly diagnosed were infected through sex between men (12 007) (Table 4). • Thirty-four per cent of people newly diagnosed were infected through heterosexual contact (9 212 cases) (Table 6). • Three per cent of people newly diagnosed were infected through injecting drug use (856) (Table 5). • Mother-to-child transmission accounted for 0.8% of new diagnoses (211 cases) (Table 7). • Transmission mode was unknown for 18% of new diagnoses (4 941). Trends in HIV diagnoses in the West Between 2005 and 2014 in the 23 countries, the rate of new diagnoses declined by 20%, from 8.0 per 100 000 population (27 429) in 2005 to 6.4 (27 325) in 2014 (not adjusted for reporting delayii). Rates increased by 10% or more in six countries and decreased by 10% or more in 11 countries (not taking into account the impact of reporting delays in several countries). ii When adjusting the 2014 rate for the West for reporting delay it increases to 7.0 per 100 000 population (29 728 cases) and the decreasing trend for the period 2005–2014 changes from a 20% decline to a 12% decline (see Annex 1 for methods and Annex 6 for results). 23 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Figure 2.14: New HIV diagnoses, by CD4 cell count per mm3 category at diagnosis and transmission mode, Centre, 2014 (n=1 376) <200 cells/mm3 n = 603 Transmission mode Sex between men 200 to <350 cells/mm3 350 to <500 cells/mm3 ≥500 cells/mm3 Heterosexual n = 566 Injecting drug use n = 207 0 20 40 60 80 100 Percentage Information about trend by transmission mode during the period 2005–2014 suggests the following (Table 8b, Figure 2.18): • New diagnoses of people infected through sex between men increased by 15% from 7 526 to 8 679 (Table 4). • New diagnoses of people infected through heterosexual contact decreased by 44% (from 11 956 to 6 739) (Table 6), with the steepest decline among cases originating from countries with generalised epidemics (see Chapter 1.2 and Figure 2.18). • New diagnoses of people infected through injecting drug use decreased by 60%, from 1 500 to 600 (Table 5). • New diagnoses of children infected through motherto-child transmission decreased by 30% from 280 to 197 (Table 7). • New diagnoses with unknown transmission mode increased by 43% from 2 772 to 3 960. AIDS cases, morbidity and mortality in the West In 2014, 3 214 people were diagnosed with AIDS as reported by 19 of the 23 countries in the Westi, giving a rate of 0.8 per 100 000 population (Table 15). Between 2005 and 2014, the rate of new AIDS cases decreased by 69%, from 2.6 (8 617 cases) to 0.8 (3 214 cases) (Figure 2.4). By mode of transmission, new AIDS diagnoses decreased in all transmission groups, most notably among people who inject drugs (a 83% decline) and people infected through heterosexual contact (a 60% decline) (Figure 2.19). The most common AIDS-indicative diseases diagnosed in the West in 2014 were Pneumocystis pneumonia (23%) and oesophageal candidiasis (11%) (Table 24). By transmission mode, the most common AIDS-indicative diseases for men infected through sex with men were i No data from Finland, Italy, San Marino and Sweden. 24 Pneumocystis pneumonia, Kaposi’s sarcoma and oesophageal candidiasis; for people who inject drugs and heterosexually infected cases it was Pneumocystis pneumonia, oesophageal candidiasis and pulmonary tuberculosis (Figure 2.20). In the West, 736 people diagnosed with AIDS were reported to have died in during 2014 in the 19 countries (Table 25), continuing the decreasing trend from 2 815 deaths in 2005 (a 74% decrease). 2.5 Number of HIV tests performed The numbers of HIV tests performed annually for diagnostic purposes (i.e. excluding unlinked anonymous tests and screening of blood donations) are presented by country in Table 27. In 2014, 26 countries (12 East, 8 Centre and 4 West) reported a total of 16 748 716 HIV tests performed. Higher testing rates tended to be reported by countries in the East and West, and lower rates by countries in the Centre. The number of tests increased by 35%, from 12 263 189 in 2005 to 16 558 233 in 2014 in 24 countries with consistent data. The number of tests increased by 10% or more in 18 countries and decreased by 10% or more in five countries. Data on the number of HIV tests can support the interpretation of trends in newly diagnosed HIV infections. In the East where the rate of newly diagnosed infections and the number of HIV tests performed both doubled during the decade in the same 12 countries, increased testing activity may have contributed to the observed increase in new diagnoses. In the Centre, however, the rate of new diagnoses also doubled while the number of HIV tests only increased by 18% (by 26% if all 14 countries are included using the most recent data point available) and it appears less likely that increased testing should have contributed to the increase in new diagnoses. HIV test data for the West are too sparse to provide the basis for a similar assessment. HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Figure 2.15: New HIV diagnoses, by transmission mode and year of diagnosis, Centre, 2005-2014 1000 Heterosexual Sex between men Injecting drug use Number of cases 800 Mother-to-child transmission Other/undetermined 600 400 200 0 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Year of diagnosis Data from Bosnia and Herzegovina excluded due to inconsistent reporting during the period; data from Poland and Turkey excluded due to incomplete reporting on transmission mode during the period. Figure 2.16: New AIDS diagnoses, by transmission mode and year of diagnosis, Centre, 2005-2014 400 Heterosexual contact Sex between men Injecting drug use Number of cases 300 Mother-to-child transmission Other/undetermined 200 100 0 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Year of diagnosis Data from Bosnia and Herzegovina excluded due to inconsistent reporting during the period. It should be noted, however, that the presented data are derived from different sources, ranging from annual reports from national HIV testing sites, to extrapolations from information systematically gathered in laboratory networks performing HIV tests and to estimates based on national surveys. Contrary to countries in the East and the Centre, many countries in the West do not systematically collect data on the number of HIV tests and in some cases only estimates are available. Also, increasing numbers of HIV tests overall do not necessarily generate a higher HIV testing yield (case detection rate) if the HIV tests are performed among people at low risk of HIV infection. 2.6 Conclusions Three decades after the beginning of HIV surveillance in Europe, HIV infection continues to be of major public health importance in the Region and of particular concern in the eastern part of the Region. In 2014, more than 142 000 people were diagnosed with HIV infection in the WHO European Regioni with a rate of 16.3 per 100 000 population – the highest number and rate ever reported for the Region. 77% of these people were diagnosed in the East of the Region with a rate of 42.4 per 100 000 population, while 19% were diagnosed in the West with i No data from Bosnia and Herzegovina, San Marino, Turkmenistan and Uzbekistan. 25 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Figure 2.17: Distribution of the three most common AIDS-defining illnesses per transmission mode, Centre, 2014 MSM IDU 32 Candidiasis, oesophageal 36 Wasting syndrome due to HIV 51 Pneumocystis pneumonia 20 Mycobacterium tuberculosis, extrapulmonary 37 Wasting syndrome due to HIV 69 Mycobacterium tuberculosis, pulmonary 52 Hetero Candidiasis, oesophageal 66 Mycobacterium tuberculosis, pulmonary 104 Wasting syndrome due to HIV 0 5 10 15 20 25 30 35 Percentage No data from Bosnia and Herzegovina. Hetero: heterosexual transmission; IDU: injecting drug use; MSM: men having sex with men. Figure 2.18: New HIV diagnoses, by transmission mode and year of diagnosis, West, 2005-2014 12000 Heterosexual Sex between men Number of cases 10000 Injecting drug use Mother-to-child 8000 Other/undetermined 6000 4000 2000 0 2007 2008coverage 2009 2010surveillance 2011 during 2012 2013 Data from Italy 2005 and Spain 2006 excluded due to increasing of national the period. 2014 Year of diagnosis Figure 2.19: New AIDS diagnoses, by transmission mode and year of diagnosis, West, 2005-2014 4000 Heterosexual contact Sex between men Injecting drug use Number of cases 3000 Mother-to-child transmission Other/undetermined 2000 1000 0 2005 2006 2007 2008 2009 2010 2011 2012 2013 Year of diagnosis Data from San Marino and Sweden excluded due to inconsistent reporting during the period. 26 2014 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT a rate of 6.4, and 3% were diagnosed in the Centre with a rate of 2.6 per 100 000. The 2014 surveillance data suggest that epidemic patterns and trends vary widely across European countries but that HIV transmission is continuing in the majority of countries, mainly among men who have sex with men in the western and central parts of the Region and among people infected heterosexually, notably women, and people who inject drugs and their sexual partners in the eastern part of the Region. A third of new HIV diagnoses were among persons originating from outside of the reporting country, including 22% originating from outside the WHO European Region. New diagnoses decreased among non-European migrants (people originating from a country outside the WHO European Region) and increased among European migrants (people originating from a European country other than the country of report), particularly in people from central and eastern Europe. Overall, the predominant transmission modes, characteristics of population groups most affected, and trends over time vary by country and geographical/epidemiological area, demonstrating the diversity in the epidemiology of HIV in Europe and corresponding responses needed. In the eastern part of the Region, HIV transmission continues with increasing intensity in most countries. The number of people newly diagnosed more than doubled in 2014 compared with ten years ago and the trend for the 13 countries with data available (Turkmenistan and Uzbekistan lacking) continues its steady increase. Of the two reporting countries that were most heavily affected at the beginning of the reporting period, Estonia and Ukraine, Estonia has truly reversed its epidemic and halved the rate of new diagnoses over the decade. Ukraine also appears to have started to halt and reverse the epidemic in the last few years due to its expansion of HIV prevention programmes for people who inject drugs that began with the influx of external support in 2006 and expanded in the years following with considerable increases in the provision of opioid substitution therapy and antiretroviral therapy for people who inject drugs [3]. While HIV transmission through injecting drug use has decreased during the decade overall and in recent years in particular, injecting drug use still accounted for 28% of new diagnoses in the East (in the countries reporting to ECDC/WHO) and for 57% of people with known transmission mode in Russia in 2014 [1]. Heterosexual transmission is the main reported mode of transmission in the East and there have been large and sustained increases in people newly infected through heterosexual contact in all countries over the past decade. At the same time, although 58% of new diagnoses were in men, new diagnoses among women increased by 74% compared with a 49% increase among men. For a considerable number of people infected through heterosexual contact, the probable source of infection was reported to be a heterosexual partner from a country without a generalised epidemic, suggesting that the increases in heterosexual transmission might be linked with periodical migration to neighbouring countries without generalised epidemics. Further, there is also evidence to suggest that a substantial proportion of men reported as heterosexually infected may in fact be men who have sex with men or injecting drug users and misclassified as heterosexually infected [4]. To halt and reverse the HIV epidemic in the East, there is an urgent need to implement and scale up bold evidence-based actions: more comprehensive prevention strategies for people at risk of heterosexual transmission and people who inject drugs, including harm reduction interventions; HIV testing services that are in line with new consolidated WHO recommendations(HIV testing by trained lay providers (community-based HIV testing) and consideration of HIV self-testing in addition to provider initiated testing); and early ART initiation in all population groups [5]. In couples where IDU MSM Figure 2.20: Distribution of the three most common AIDS-defining illnesses per transmission mode, West, 2014 354 Pneumocystis pneumonia 188 Kaposi’s sarcoma 106 Candidiasis, oesophageal 57 Pneumocystis pneumonia 56 Candidiasis, oesophageal 43 Hetero Mycobacterium tuberculosis, pulmonary 439 Pneumocystis pneumonia 181 Candidiasis, oesophageal 171 Mycobacterium tuberculosis, pulmonary 0 5 10 15 20 25 30 Percentage No data from San Marino or Sweden. Hetero: heterosexual transmission; IDU: injecting drug use; MSM: men having sex with men. 27 HIV/AIDS surveillance in Europe 2014 one of the partners engages in high-risk behaviour, such as injecting drug use, purchased sex, bisexual relations or is working abroad for longer periods of time, prevention interventions should address the risk of heterosexual transmission, including the use of preexposure prophylaxis where relevant and according to WHO recommendations [6, 7]. The removal of laws and policies that hamper access to, and uptake of, key HIV prevention and treatment services for key populations could facilitate further progress in the reduction of HIV transmission among people who inject drugs and their partners. In the central part of the Region, the HIV epidemic remains at a low level although the rate of new diagnoses increased more in the Centre than in any other part of the WHO European Region and the number of new diagnoses is increasing in almost all countries. The epidemic in this part of Europe is diverse but sexual transmission prevails (with sex between men dominating over heterosexual transmission in the majority of countries) and men are far more affected than women in comparison with other parts of Europe. Recent increasing trends in new diagnoses are mostly driven by sustained increases among people infected through sex between men although new diagnoses in people infected through heterosexual contact also increased. Increases of HIV among people who inject drugs in the EU/EEA in recent years indicate that even low numbers can rapidly evolve into an outbreak when public health interventions are insufficient [8]. In the western part of the Region, the HIV epidemic remains constant overall but with continuing and increasing transmission among men who have sex with men. This population group accounts for the highest number of new diagnoses in the West in 2014 and is the only group where the trend continues to increase. Despite considerable efforts to prevent and control HIV among MSM in the West, further strengthening of combination HIV prevention strategies appears to be needed [7, 9, 10]. Recent guidance by WHO now recommends that countries consider offering pre-exposure prophylaxis as an additional prevention choice for people at substantial risk of HIV infection as part of combination prevention approaches [6]. Heterosexual transmission is decreasing, both among people originating from countries with a generalised epidemic and among nonmigrant heterosexuals. There is also evidence that a certain proportion of migrants, even those originating from HIV-endemic areas, acquire HIV after arrival in the EU/EEA [3, 4]. The extent to which the observed decreases can be explained by decreased incidence of HIV in migrant populations, decreased testing, changed migration patterns, or a combination of factors, is unclear. Despite these decreasing trends, the public health challenge of ensuring access to health services for migrant populations in general, and to HIV prevention, testing, treatment and care services specifically, remains as relevant as ever in Europe in 2015. 28 SURVEILLANCE REPORT It is of major concern that 48% of people newly diagnosed are detected late with CD4 cell counts below 350 per mm3 at diagnosis, and that, further, 28% of the newly diagnosed have CD4 cell counts below 200 per mm3. Among people infected through injecting drug use in the East, fully 68% had CD4 cell counts below 350 per mm3 at the time of their HIV diagnosis. These so-called late presenters reflect the low access to, and uptake of, HIV testing and counselling by those most at risk. Delayed initiation of antiretroviral treatment decreases the clinical benefits as well as the impact of treatment on preventing further HIV transmission. HIV testing strategies need to be reconsidered, including innovative approaches that consider the new consolidated WHO guidance on HIV testing service and focus on the most affected population groups and with services tailored to the specific needs of these groups. Support for timely linkage to HIV prevention, treatment and care is also essential. Appropriate HIV testing services delivered at sufficient scale are key to support progress towards the three UN 90:90:90 targets (90% of people living with HIV know their HIV status, 90% of diagnosed people living with HIV receive treatment, and 90% of people on treatment achieve viral suppression) [11], with improved treatment outcomes and reductions in further HIV transmission. AIDS trends varied greatly across the three geographical areas. While the rate continued its steady decline in the West, it increased slightly in the Centre and dramatically in the East of the Region. The high number of AIDS cases in the East is indicative of late HIV diagnosis, low treatment coverage and delayed initiation of life-saving HIV treatment. New WHO treatment guidance now recommends that antiretroviral therapy should be initiated for all persons living with HIV, irrespective of CD4 cell count [6, 12]. Improved access to, and earlier initiation of, treatment, particularly for key populations and discordant couples, is needed throughout Europe but particularly in the eastern part of the WHO European Region. The number of countries conducting enhanced surveillance for HIV in Europe has increased over the years. Enhanced HIV surveillance in Europe is essential to provide the strategic information for monitoring the epidemic and guiding the public health response to HIV. Interventions to control the epidemic need to be based on evidence and adapted to national and local epidemiology. In order to achieve this aim, surveillance data should be of high quality and provide complete case reports linked with clinical markers and with information about key variables such as transmission mode, probable country and source of infection and origin. SURVEILLANCE REPORT HIV/AIDS surveillance in Europe 2014 References 1 Russian Federal Scientific and Methodological Center for Prevention and Control of AIDS. Information note ‘Spravka’ on HIV infection in the Russian Federation as of 31 December 2014. Moscow: Russian Federal Scientific and Methodological Center for Prevention and Control of AIDS; 2015. Available at: http://hivrussia.org/files/ spravkaHIV2014.pdf. 2 Russian Federal Scientific and Methodological Center for Prevention and Control of AIDS. HIV-infection Bulletin number 39. Moscow: The Federal Service for Surveillance of Consumer Rights Protection and human well-being; 2014. 3 Vitek CR, Čakalo JI, Kruglov YV, Dumchev KV, Salyuk TO, Božičević I, et al. Slowing of the HIV epidemic in Ukraine: evidence from case reporting and key population surveys, 2005-2012. PLoS One. 2014;9(9):e103657. 4 Čakalo JI, Božičević I, Vitek CR, Mandel JS, Salyuk TO, Rutherford GW. Misclassification of Men with Reported HIV Infection in Ukraine. AIDS Behav. 2015;19:1938-1940. 5 World Health Organization. Consolidated guidelines on HIV testing services. Geneva: World Health Organization; 2015. 6 World Health Organization. Guidelines on when to start antiretroviral therapy and on pre-exposure prophylaxis for HIV. Geneva: World Health Organization; 2015. 7 World Health Organization. Consolidated guidelines on HIV prevention, diagnosis, treatment and care for key populations. Geneva: World Health Organization; 2014. 8 Hedrich D, Kalamara E, Sfetcu O, Pharris A, Noor A, Wiessing L, et al. Human immunodeficiency virus among people who inject drugs: Is risk increasing in Europe? Euro Surveill. 2013;18(48):pii=20648. Available online: http://www.eurosurveillance.org/ViewArticle. aspx?ArticleId=20648 9 European Centre for Disease Prevention and Control. HIV and STI prevention among men who have sex with men. ECDC Guidance. Stockholm: ECDC; 2014. Available at: http://ecdc.europa.eu/en/ publications/Publications/hiv-sti-prevention-among-men-whohave-sex-with-men-guidance.pdf 10 United Nations Population Fund, Global Forum on MSM and HIV, United Nations Development Programme, World Health Organization, United States Agency for International Development, the US President’s Emergency Plan for AIDS Relief, and the Bill & Melinda Gates Foundation. Implementing comprehensive HIV and STI programmes with men who have sex with men. New York (NY): United Nations Population Fund; 2015. 11UNAIDS. Ambitious treatment targets: Writing the final chapter of the AIDS epidemic. Geneva; 2014. Available at: h t t p://w w w. u n a i d s .o r g /s i t e s/d e f a u l t /f i l e s/m e d i a _ a s s e t / JC2670_UNAIDS_Treatment_Targets_en.pdf 12 INSIGHT START Study Group. Initiation of antiretrovial therapy in early asymptomatic HIV infection. N Engl J Med. 2015;373(9):795-807. 29 HIV/AIDS surveillance in Europe 2014 30 SURVEILLANCE REPORT SURVEILLANCE REPORT HIV/AIDS surveillance in Europe 2014 Tables 31 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 1: New HIV diagnoses and rates per 100 000 population, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region Area Country* EU/EEA West Austria West Belgium Centre Bulgaria Centre Croatia Centre Cyprus Centre Czech Republic West Denmark East Estonia West Finland West France West Germany West Greece Centre Hungary West Iceland West Ireland West Italy East Latvia Liechtenstein East Lithuania West Luxembourg West Malta West Netherlands West Norway Centre Poland West Portugal Centre Romania Centre Slovakia Centre Slovenia West Spain West Sweden West United Kingdom Total EU/EEA Non-EU/EEA Centre Albania West Andorra East Armenia East Azerbaijan East Belarus Centre Bosnia and Herzegovina Centre former Yugoslav Republic of Macedonia, the East Georgia West Israel East Kazakhstan East Kyrgyzstan East Moldova West Monaco Centre Montenegro East Russia*** West San Marino Centre Serbia**** West Switzerland East Tajikistan Centre Turkey***** East Turkmenistan East Ukraine East Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region Year of start of reporting 2005 2006 2007 2008 2009 N Rate N Rate N Rate N Rate N Rate 1980 1985 1986 1985 1986 1985 1990 1988 1980 2003 1993 1984 1985 1983 1981 2004 1987 1985 1988 1983 2001 1980 1984 1985 1985 1987 1985 1985 2003 1983 1981 339 1070 83 68 41 90 264 621 134 5995 2492 539 106 8 325 1490 299 0 120 55 15 1231 219 705 2225 597 21 38 1654 396 7889 29129 4.1 10.2 1.1 1.6 5.6 0.9 4.9 45.7 2.6 9.6 3.0 4.9 1.0 2.7 7.9 7.6 13.3 0.0 3.6 11.9 3.7 7.5 4.8 1.8 21.2 2.8 0.4 1.9 9.4 4.4 13.1 6.7 341 1018 91 57 34 91 245 668 191 5698 2643 506 81 11 353 2018 299 2 100 54 24 1144 276 811 2270 494 27 33 1784 397 7447 29208 4.1 9.7 1.2 1.3 4.6 0.9 4.5 49.5 3.6 9 3.2 4.6 0.8 3.7 8.4 8.4 13.4 5.7 3 11.5 5.9 7 5.9 2.1 21.6 2.3 0.5 1.6 10 4.4 12.3 6.6 356 1072 126 49 45 121 306 633 187 5679 2772 557 119 13 391 2221 350 0 106 45 14 1238 248 807 2173 480 39 37 2805 488 7354 30831 4.3 10.1 1.7 1.1 5.9 1.2 5.6 47.1 3.5 8.9 3.4 5 1.2 4.2 9 7.2 15.8 0 3.3 9.5 3.5 7.6 5.3 2.1 20.6 2.3 0.7 1.8 11.5 5.4 12 6.8 373 1092 123 71 37 148 285 545 147 5766 2830 612 145 10 404 2482 358 0 95 59 28 1321 299 839 2242 563 53 48 3471 426 7220 32092 4.5 10.2 1.6 1.6 4.8 1.4 5.2 40.7 2.8 9 3.4 5.5 1.4 3.2 9.1 6.7 16.3 0 3 12.2 6.9 8.1 6.3 2.2 21.2 2.7 1 2.4 12.4 4.6 11.7 6.9 311 1132 171 55 38 156 236 411 172 5458 2868 607 140 15 395 3825 275 1 180 60 19 1207 282 961 2041 550 53 48 3628 431 6659 32385 3.7 10.5 2.3 1.3 4.8 1.5 4.3 30.8 3.2 8.5 3.5 5.4 1.4 4.7 8.7 6.6 12.7 2.8 5.7 12.2 4.6 7.3 5.9 2.5 19.3 2.7 1 2.4 11.1 4.7 10.7 6.6 1993 2004 1988 1987 1981 1986 1993 1989 1981 1987 1987 1987 1985 1989 2010 1985 1984 1985 1991 1985 1990 1987 1981 31 6 75 206 751 13 1 239 355 958 171 533 0 10 4 103 724 220 271 0 11464 2159 18294 1 7.8 2.5 2.4 7.8 0.3 0 5.3 5.4 6.2 3.3 12.8 0 1.6 13.5 1.1 9.8 3.2 0.4 0 24.5 8.3 7.9 33 1 68 239 733 11 8 278 337 1729 244 621 1 8 2 88 760 201 276 0 13456 2205 21299 1.1 1.3 2.3 2.8 7.6 0.3 0.4 6.3 5 11.1 4.7 15 3 1.3 6.7 1 10.2 2.9 0.4 0 28.9 8.4 9.2 43 5 107 437 990 4 5 341 365 1973 409 731 1 9 0 91 757 350 349 0 13469 3169 23605 1.4 6.2 3.6 5 10.4 0.1 0.2 7.8 5.3 12.5 7.8 17.7 3 1.5 0 1 10 4.9 0.5 0 29.1 11.9 10.1 52 3 136 433 881 9 4 355 394 2321 553 793 0 11 4 118 763 362 396 0 15444 3061 26093 1.8 3.6 4.6 4.9 9.2 0.2 0.2 8.2 5.6 14.6 10.4 19.3 0 1.8 12.5 1.3 10 5 0.6 0 33.6 11.4 11.1 64 2 149 455 1072 6 6 387 387 2078 696 704 0 14 1 131 654 444 471 0 16268 4055 28044 2.2 2.4 5 5.1 11.3 0.2 0.3 9 5.3 12.9 12.9 17.2 0 2.3 3.2 1.4 8.5 6 0.7 0 35.5 14.8 11.8 27429 2178 17816 47423 8 1.2 13 7.1 27521 2143 20841 50507 7.9 1.1 15.2 7.5 29047 2324 23065 54436 8 1.2 16.8 7.9 30231 2617 25337 58185 8.1 1.4 18.4 8.3 30390 2864 27174 60429 7.6 1.5 19.6 8.3 * Country-specific comments are in Annex 5 ** Cumulative total is the total number of cases reported by the country since the start of reporting *** No official data were reported by Russia, except for 2010. Information about new and cumulative HIV diagnoses was obtained from the Federal Scientific and Methodological Center for Prevention and Control of AIDS: 2005 (35 401), 2006 (39 312), 2007 (45 099), 2008 (54 799), 2009 (58 142), 2010 (58 305), 2011 (62 385), 2012 (70 744), 2013 (79 728), 2014 (85 252), cumulative as of 31 December 2014 (907 607). Reference: HIV-infection bulletin number 39, available from http://hivrussia.org/files/bul_39.pdf and Spravka HIV 2014, available from http://hivrussia.org/files/spravkaHIV2014.pdf. 32 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT 2010 2011 2012 2013 2014 Cumulative Country* total** N Rate N Rate N Rate N Rate N Rate 332 1198 163 70 41 180 275 376 184 5539 2714 639 182 24 330 4027 274 4 153 53 18 1206 258 957 1937 553 28 35 3748 457 6348 32303 4 11.1 2.2 1.6 5 1.7 5 28.2 3.4 8.6 3.3 5.7 1.8 7.6 7.3 6.8 12.9 11.1 4.9 10.6 4.3 7.3 5.3 2.5 18.3 2.7 0.5 1.7 11.4 4.9 10.2 6.5 328 1183 201 77 54 153 266 366 172 5416 2699 953 162 23 328 3889 299 1 166 56 21 1151 269 1120 1685 784 49 55 3493 391 6181 31991 3.9 10.8 2.7 1.8 6.4 1.5 4.8 27.5 3.2 8.3 3.3 8.6 1.6 7.2 7.2 6.6 14.4 2.8 5.4 10.9 5.1 6.9 5.5 2.9 15.9 3.9 0.9 2.7 10.6 4.2 9.8 6.5 326 1229 157 74 58 212 201 315 156 5668 2978 1142 219 19 349 4144 339 0 160 58 30 1062 242 1098 1607 870 50 45 3732 381 6247 33168 3.9 11.1 2.1 1.7 6.7 2 3.6 23.8 2.9 8.7 3.6 10.3 2.2 5.9 7.6 7 16.6 0 5.3 11.1 7.2 6.3 4.9 2.9 15.2 4.3 0.9 2.2 9.9 4 9.8 6.6 266 1125 200 85 54 235 233 325 157 5525 3288 864 240 11 343 3811 340 0 177 61 36 1014 233 1103 1464 898 83 44 3866 354 6024 32459 3.1 10.1 2.7 2 6.2 2.2 4.2 24.6 2.9 8.4 4 7.9 2.4 3.4 7.5 6.4 16.8 0 6 11.4 8.5 6 4.6 2.9 14 4.5 1.5 2.1 8.3 3.7 9.4 6.3 235 1039 247 92 56 232 256 291 181 4327 3525 714 271 11 359 3695 347 1 141 69 40 831 268 1061 920 791 86 49 3366 350 6141 29992 2.8 9.3 3.4 2.2 6.5 2.2 4.5 22.1 3.3 6.6 4.4 6.5 2.7 3.4 7.8 6.1 17.3 2.7 4.8 12.6 9.4 4.9 5.2 2.8 8.8 4 1.6 2.4 7.2 3.6 9.5 5.9 8420 27896 2077 1206 903 2354 6828 8993 3399 65929 53760 14440 2845 321 7345 33268 6214 65 2378 1348 263 23076 5638 18757 52694 20536 625 683 34690 11137 139778 557866 43 5 149 459 1069 7 5 457 424 1987 567 703 0 15 62581 6 148 605 995 524 0 16617 3795 91161 1.5 5.9 5 5 11.3 0.2 0.2 10.8 5.7 12.2 10.4 17.2 0 2.4 43.7 19.2 1.6 7.7 13.1 0.7 0 36.4 13.7 23.9 78 2 182 548 1196 27 1 429 450 1999 614 721 0 9 8 127 559 978 654 0 17305 25887 2.7 2.6 6.1 5.9 12.6 0.7 0 10.2 5.9 12.1 11.1 17.7 0 1.4 25.1 1.4 7.1 12.6 0.9 0 38.1 12.2 81 2 228 517 1223 25 15 534 487 2011 701 757 0 14 5 130 621 849 1069 0 16850 26119 2.8 2.6 7.7 5.5 12.9 0.7 0.7 12.9 6.3 12 12.4 18.6 0 2.2 15 1.4 7.7 10.7 1.4 0 37.2 12.2 119 5 238 514 1533 27 15 480 473 2140 503 706 0 10 1 148 576 893 1319 17860 27560 4.1 6.6 8 5.4 16.1 0.7 0.7 11.8 6.1 12.5 8.8 17.3 0 1.6 3 1.7 7.1 11 1.7 39.5 12.7 77 3 332 604 1811 30 536 477 2350 645 831 0 20 3 126 515 985 1812 15796 26953 2.7 3.9 11 6.3 19.1 1.4 13.3 6 13.5 11 20.4 0 3.2 8.9 1.4 6.3 11.9 2.3 36.9 12.7 780 71 1953 4902 17522 250 101 4695 8465 24220 5758 9371 34 175 62581 85 3175 34461 6558 8589 2 219543 24018 437409 30327 2951 90182 123464 7.5 1.6 31.9 14.1 29523 3551 24803 57878 7.3 1.9 22.2 8.2 30686 4117 24484 59287 7.4 2.1 21.8 8.3 29730 4580 25709 60019 7 2.4 22.8 8.2 27325 4950 24669 56945 6.4 2.6 22.3 7.9 533346 63056 398708 995175 EU/EEA Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein Lithuania Luxembourg Malta Netherlands Norway Poland Portugal Romania Slovakia Slovenia Spain Sweden United Kingdom Total EU/EEA Non-EU/EEA Albania Andorra Armenia Azerbaijan Belarus Bosnia and Herzegovina former Yugoslav Republic of Macedonia, the Georgia Israel Kazakhstan Kyrgyzstan Moldova Monaco Montenegro Russia*** San Marino Serbia**** Switzerland Tajikistan Turkey***** Turkmenistan Ukraine Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region **** Includes data from Kosovo (without prejudice to positions on status, and in line with UNSCR 1244 and the ICJ Opinion on the Kosovo Declaration of Independence): 2005 (0, 0.0), 2006 (2, 0.1), 2007 (1, 0.0), 2008 (3, 0.1), 2009 (6, 0.3), 2010 (0, 0.0), 2011 (3, 0.2), 2012 (3, 0.2), 2013 (2, 0.1), 2014 (6, 0.3), cumulative 2000-2014 (46). ***** The 1812 new HIV diagnoses for Turkey in 2014 differ from national statistics for 2014 due to 6 cases diagnosed in 2013 and 8 cases diagnosed in the period 2001-2012. 33 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 1a: New HIV diagnoses and rates per 100 000 population, by country and year of statistics (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region Area Country* EU/EEA West Austria West Belgium Centre Bulgaria Centre Croatia Centre Cyprus Centre Czech Republic West Denmark East Estonia West Finland West France West Germany West Greece Centre Hungary West Iceland West Ireland West Italy East Latvia Liechtenstein East Lithuania West Luxembourg West Malta West Netherlands West Norway Centre Poland West Portugal Centre Romania Centre Slovakia Centre Slovenia West Spain West Sweden West United Kingdom Total EU/EEA Non-EU/EEA Centre Albania West Andorra East Armenia East Azerbaijan East Belarus Centre Bosnia and Herzegovina Centre former Yugoslav Republic of Macedonia, the East Georgia West Israel East Kazakhstan East Kyrgyzstan East Moldova West Monaco Centre Montenegro East Russia*** West San Marino Centre Serbia**** West Switzerland East Tajikistan Centre Turkey East Turkmenistan East Ukraine East Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region 2005 N Rate 2006 N Rate 2007 N Rate 2008 N Rate 2009 N Rate 339 1070 83 68 41 90 264 621 134 5995 2492 566 106 8 325 1490 299 120 62 15 1231 219 705 2225 597 21 38 1654 388 7889 29155 4.1 10.2 1.1 1.6 5.6 0.9 4.9 45.7 2.6 9.6 3 5.1 1 2.7 7.9 7.6 13.3 0 3.6 13.4 3.7 7.5 4.8 1.8 21.2 2.8 0.4 1.9 9.4 4.3 13.1 6.7 341 1018 91 57 34 91 245 668 191 5698 2643 572 81 11 353 2018 299 2 100 57 22 1144 276 811 2270 494 27 33 1784 385 7447 29263 4.1 9.7 1.2 1.3 4.6 0.9 4.5 49.5 3.6 9 3.2 5.1 0.8 3.7 8.4 8.4 13.4 5.7 3 12.2 5.4 7 5.9 2.1 21.6 2.3 0.5 1.6 10 4.3 12.3 6.6 356 1072 126 49 45 121 306 633 187 5679 2772 521 119 13 391 2221 350 106 48 16 1238 248 807 2173 480 39 37 2805 528 7354 30840 4.3 10.1 1.7 1.1 5.9 1.2 5.6 47.1 3.5 8.9 3.4 4.7 1.2 4.2 9 7.2 15.8 0 3.3 10.1 3.9 7.6 5.3 2.1 20.6 2.3 0.7 1.8 11.5 5.8 12 6.8 373 1092 123 71 37 148 285 545 147 5766 2830 659 145 10 404 2482 358 95 68 28 1321 299 839 2242 563 53 48 3471 441 7220 32163 4.5 10.2 1.6 1.6 4.8 1.4 5.2 40.7 2.8 9 3.4 5.9 1.4 3.2 9.1 6.7 16.3 0 3 14.1 6.9 8.1 6.3 2.2 21.2 2.7 1 2.4 12.4 4.8 11.7 6.9 311 1132 171 55 38 156 236 411 172 5458 2868 611 141 15 395 3825 275 1 180 64 18 1207 282 961 2041 550 53 48 3628 485 6659 32447 3.7 10.5 2.3 1.3 4.8 1.5 4.3 30.8 3.2 8.5 3.5 5.5 1.4 4.7 8.7 6.6 12.7 2.8 5.7 13 4.4 7.3 5.9 2.5 19.3 2.7 1 2.4 11.1 5.2 10.7 6.6 30 10 75 206 751 13 1 242 355 958 171 533 0 10 4 103 724 220 298 0 11464 2159 18327 1 13 2.5 2.4 7.8 0.3 0 5.4 5.4 6.2 3.3 12.8 0 1.6 13.5 1.1 9.8 3.2 0.4 0 24.5 8.3 7.9 32 1 66 239 733 17 8 276 337 1729 244 621 1 8 2 88 760 201 260 0 13456 2205 21284 1 1.3 2.2 2.8 7.6 0.4 0.4 6.2 5 11.1 4.7 15 3 1.3 6.7 1 10.2 2.9 0.4 0 28.9 8.4 9.2 43 3 109 437 990 4 5 344 365 1973 409 731 1 9 0 91 757 350 399 0 13469 3169 23658 1.4 3.7 3.6 5 10.4 0.1 0.2 7.8 5.3 12.5 7.8 17.7 3 1.5 0 1 10 4.9 0.6 0 29.1 11.9 10.1 48 4 136 433 881 9 4 351 394 2321 551 793 0 11 4 118 763 362 393 0 15444 3061 26081 1.6 4.8 4.6 4.9 9.2 0.2 0.2 8.1 5.6 14.6 10.4 19.3 0 1.8 12.5 1.3 10 5 0.6 0 33.6 11.4 11.1 61 2 149 455 1072 7 6 385 387 2078 687 704 0 14 1 131 654 444 470 0 16268 4041 28016 2.1 2.4 5 5.1 11.3 0.2 0.3 9 5.3 12.9 12.8 17.2 0 2.3 3.2 1.4 8.5 6 0.7 0 35.5 14.8 11.8 27459 2204 17819 47482 8 1.2 13 7.1 27576 2132 20837 50547 7.9 1.1 15.2 7.5 29054 2374 23070 54498 8 1.3 16.8 7.9 30303 2610 25331 58244 8.1 1.4 18.4 8.3 30451 2862 27149 60463 7.6 1.5 19.6 8.3 * Country-specific comments are in Annex 5 ** Cumulative total is the total number of cases reported by the country since the start of reporting *** No official data were reported by Russia, except for 2010. Information about new and cumulative HIV diagnoses was obtained from the Federal Scientific and Methodological Center for Prevention and Control of AIDS: 2005 (35 401), 2006 (39 312), 2007 (45 099), 2008 (54 799), 2009 (58 142), 2010 (58 305), 2011 (62 385), 2012 (70 744), 2013 (79 728), 2014 (85 252), cumulative as of 31 December 2014 (907 607). Reference: HIV-infection bulletin number 39, available from http://hivrussia.org/files/bul_39.pdf and Spravka HIV 2014, available from http://hivrussia.org/files/spravkaHIV2014.pdf. **** Includes data from Kosovo (without prejudice to positions on status, and in line with UNSCR 1244 and the ICJ Opinion on the Kosovo Declaration of Independence): 2005 (0), 2006 (2), 2007 (1), 2008 (3), 2009 (6), 2010 (0), 2011 (3), 2012 (3), 2013 (2), 2014 (6), cumulative 2000-2014 (46). 34 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT 2010 N Rate 2011 N Rate 2012 N Rate 2013 N Rate 2014 N Rate Cumulative Country* total** 332 1198 163 70 41 180 275 372 184 5539 2714 613 182 24 330 4027 274 4 153 63 19 1206 258 957 1937 553 28 35 3748 493 6348 32320 4 11.1 2.2 1.6 5 1.7 5 27.9 3.4 8.6 3.3 5.5 1.8 7.6 7.3 6.8 12.9 11.1 4.9 12.5 4.6 7.3 5.3 2.5 18.3 2.7 0.5 1.7 11.4 5.3 10.2 6.5 328 1183 201 77 54 153 266 370 172 5416 2699 969 162 23 326 3889 299 1 166 73 21 1151 269 1120 1685 784 49 55 3493 461 6181 32096 3.9 10.8 2.7 1.8 6.4 1.5 4.8 27.8 3.2 8.3 3.3 8.7 1.6 7.2 7.1 6.6 14.4 2.8 5.4 14.3 5.1 6.9 5.5 2.9 15.9 3.9 0.9 2.7 10.6 4.9 9.8 6.5 326 1229 157 74 58 212 201 315 156 5668 2978 1188 219 19 340 4144 339 160 83 30 1062 242 1098 1607 870 50 45 3732 441 6247 33290 3.9 11.1 2.1 1.7 6.7 2 3.6 23.8 2.9 8.7 3.6 10.7 2.2 5.9 7.4 7 16.6 0 5.3 15.8 7.2 6.3 4.9 2.9 15.2 4.3 0.9 2.2 9.9 4.7 9.8 6.6 266 1125 200 85 54 235 233 325 157 5525 3288 921 240 11 343 3811 340 177 82 36 1014 233 1103 1464 898 83 44 3866 458 6024 32641 3.1 10.1 2.7 2 6.2 2.2 4.2 24.6 2.9 8.4 4 8.4 2.4 3.4 7.5 6.4 16.8 0 6 15.3 8.5 6 4.6 2.9 14 4.5 1.5 2.1 8.3 4.8 9.4 6.4 235 1039 247 92 56 232 256 291 181 4327 3525 806 271 11 370 3695 347 1 141 96 40 831 268 1061 920 791 86 49 3366 350 6141 30122 2.8 9.3 3.4 2.2 6.5 2.2 4.5 22.1 3.3 6.6 4.4 7.4 2.7 3.4 8 6.1 17.3 2.7 4.8 17.5 9.4 4.9 5.2 2.8 8.8 4 1.6 2.4 7.2 3.6 9.5 5.9 8420 27896 2077 1206 903 2354 6828 8993 3399 65929 53760 14440 2845 321 7345 33268 6214 65 2378 1348 263 23076 5638 18757 52694 20536 625 683 34690 11137 139778 557866 48 6 148 459 1069 7 5 455 424 1987 570 703 0 15 62581 6 148 605 995 489 0 16617 3809 91146 1.7 7.1 5 5 11.3 0.2 0.2 10.7 5.7 12.2 10.4 17.2 0 2.4 43.7 19.2 1.6 7.7 13.1 0.7 0 36.4 13.7 23.9 72 2 182 548 1196 28 1 424 450 1999 598 721 0 9 8 127 559 978 699 0 17305 25906 2.5 2.6 6.1 5.9 12.6 0.7 0 10.1 5.9 12.1 10.8 17.7 0 1.4 25.1 1.4 7.1 12.6 1 0 38.1 12.2 90 2 228 517 1223 25 14 526 487 2011 724 757 0 14 5 130 621 849 1068 0 16850 26141 3.1 2.6 7.7 5.5 12.9 0.7 0.7 12.7 6.3 12 12.8 18.6 0 2.2 15 1.4 7.7 10.7 1.4 0 37.2 12.2 124 7 238 514 1533 27 17 490 473 2140 504 706 0 10 1 148 576 893 1313 17860 27574 4.3 9.2 8 5.4 16.1 0.7 0.8 12 6.1 12.5 8.8 17.3 0 1.6 3 1.7 7.1 11 1.7 39.5 12.7 84 3 334 604 1811 29 564 477 2350 645 831 0 20 3 126 515 985 1826 15796 27015 2.9 3.9 11.1 6.3 19.1 1.4 14 6 13.5 11 20.4 0 3.2 8.9 1.4 6.3 11.9 2.4 36.9 12.7 780 71 1953 4902 17522 250 101 4695 8465 24220 5758 9371 34 175 62581 85 3175 34461 6558 8601 2 219543 24018 437409 30349 2921 90192 123466 7.5 1.5 31.9 14.1 29624 3591 24786 58002 7.3 1.9 22.2 8.2 30808 4124 24499 59431 7.5 2.2 21.8 8.3 29914 4581 25720 60215 7.1 2.4 22.8 8.3 27455 4982 24699 57137 6.5 2.6 22.3 7.9 533346 63056 398708 995175 EU/EEA Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein Lithuania Luxembourg Malta Netherlands Norway Poland Portugal Romania Slovakia Slovenia Spain Sweden United Kingdom Total EU/EEA Non-EU/EEA Albania Andorra Armenia Azerbaijan Belarus Bosnia and Herzegovina former Yugoslav Republic of Macedonia, the Georgia Israel Kazakhstan Kyrgyzstan Moldova Monaco Montenegro Russia*** San Marino Serbia**** Switzerland Tajikistan Turkey Turkmenistan Ukraine Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region 35 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 2: New HIV diagnoses in males and rates per 100 000 population, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region Area Country* EU/EEA West Austria West Belgium Centre Bulgaria Centre Croatia Centre Cyprus Centre Czech Republic West Denmark East Estonia West Finland West France West Germany West Greece Centre Hungary West Iceland West Ireland West Italy East Latvia Liechtenstein East Lithuania West Luxembourg West Malta West Netherlands West Norway Centre Poland West Portugal Centre Romania Centre Slovakia Centre Slovenia West Spain West Sweden West United Kingdom Total EU/EEA Non-EU/EEA Centre Albania West Andorra East Armenia East Azerbaijan East Belarus Centre Bosnia and Herzegovina Centre former Yugoslav Republic of Macedonia, the East Georgia West Israel East Kazakhstan East Kyrgyzstan East Moldova West Monaco Centre Montenegro East Russia West San Marino Centre Serbia*** West Switzerland East Tajikistan Centre Turkey East Turkmenistan East Ukraine East Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region 2005 N Rate 2006 N Rate 2007 N Rate 2008 N Rate 2009 N 246 622 56 58 26 70 193 391 95 3697 1975 409 80 5 188 1067 193 0 90 31 9 937 122 512 1535 323 15 35 1262 229 4660 19131 6.2 12.2 1.5 2.8 7.2 1.4 7.2 61.9 3.7 12.2 4.9 7.5 1.7 3.4 9.2 11.3 18.7 0 5.8 13.6 4.5 11.6 5.3 2.8 30.4 3.1 0.6 3.6 14.5 5.1 15.8 9 256 674 71 48 20 71 174 429 134 3572 2121 402 49 8 221 1480 185 1 78 38 16 917 179 607 1525 269 20 30 1389 243 4500 19727 6.4 13.1 1.9 2.3 5.5 1.4 6.5 68.3 5.2 11.7 5.3 7.3 1 5.3 10.5 12.6 18.1 5.8 5.1 16.4 8 11.4 7.8 3.3 30.1 2.6 0.8 3.1 15.8 5.4 15.2 9.2 277 661 105 44 30 97 224 374 136 3664 2299 467 88 6 242 1604 224 0 74 33 8 998 166 575 1442 268 32 35 2216 304 4710 21403 6.9 12.8 2.8 2.1 8.1 1.9 8.3 59.9 5.3 11.9 5.7 8.5 1.8 3.8 11.1 10.7 22.1 0 4.9 14 4 12.3 7.1 3.1 28.5 2.6 1.2 3.5 18.6 6.7 15.8 9.6 281 745 102 68 24 121 204 315 105 3747 2340 508 110 7 258 1814 231 0 65 48 17 1116 182 615 1533 318 48 45 2761 267 4597 22592 7 14.3 2.8 3.3 6.3 2.4 7.5 50.6 4 12.1 5.8 9.2 2.3 4.4 11.6 10 22.9 0 4.4 20 8.4 13.8 7.7 3.3 30.2 3.2 1.8 4.6 20 5.9 15.2 9.9 246 748 133 49 26 130 179 243 106 3595 2394 511 109 6 258 2881 170 1 131 43 10 1000 183 733 1382 331 48 40 2915 281 4469 23351 6.1 14.2 3.7 2.4 6.7 2.5 6.6 39.1 4.1 11.5 6 9.3 2.3 3.7 11.5 10.3 17.1 5.7 8.9 17.6 4.9 12.3 7.6 4 27.3 3.3 1.8 4 18.1 6.1 14.7 9.7 23 5 60 172 399 8 0 173 226 692 122 316 0 10 2 87 478 198 179 0 6756 1715 11621 1.5 12.5 4.1 4.1 8.9 0.4 0 8.2 6.9 9.3 4.8 15.9 0 3.3 13.7 1.9 13.2 5.8 0.5 0 31.1 13.4 10.5 23 0 43 213 391 9 2 201 219 1278 181 369 1 6 2 73 498 152 193 0 7890 1683 13427 1.5 0 2.9 5 8.7 0.5 0.2 9.6 6.6 17 7.1 18.6 6.2 2 13.6 1.6 13.6 4.4 0.6 0 36.6 13 11.9 29 5 75 380 540 4 2 243 247 1391 287 422 1 8 0 75 524 268 248 0 8198 2087 15034 1.9 11.8 5 8.8 12.1 0.2 0.2 11.7 7.2 18.4 11.1 21.3 6.2 2.6 0 1.7 14.1 7.5 0.7 0 38.3 15.9 13.3 35 3 104 350 454 7 3 253 251 1642 309 438 0 8 2 98 550 285 273 0 8641 1830 15536 2.3 6.9 6.8 8 10.2 0.4 0.3 12.3 7.2 21.4 11.8 22.2 0 2.6 12.2 2.2 14.6 7.8 0.8 0 40.6 13.8 13.6 45 2 96 377 562 6 6 278 267 1393 514 400 0 12 1 122 468 337 345 0 9089 2248 16568 3 4.5 6.3 8.5 12.7 0.3 0.6 13.6 7.4 18 19.4 20.3 0 3.9 6.5 2.7 12.3 9 1 0 42.9 16.7 14.4 17993 1482 11277 30752 10.7 1.6 17.2 9.5 18569 1491 13093 33154 10.9 1.6 20 10.1 20234 1640 14563 36437 11.4 1.8 22.2 10.9 21336 1875 14917 38128 11.6 2 22.6 11.2 21945 2135 15838 39919 11.2 2.3 23.9 11.2 * Country-specific comments are in Annex 5 ** Cumulative total is the total number of cases reported by the country since the start of reporting *** Includes data from Kosovo (without prejudice to positions on status, and in line with UNSCR 1244 and the ICJ Opinion on the Kosovo Declaration of Independence): 2005 (0), 2006 (2), 2007 (1), 2008 (3), 2009 (5), 2010 (0), 2011 (3), 2012 (2), 2013 (2), 2014 (5), cumulative 2000-2014 (34). 36 Rate HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT 2010 N Rate 2011 N Rate 2012 N Rate 2013 N Rate 2014 N Rate Cumulative Country* total** 265 794 132 67 34 159 201 230 130 3651 2301 561 142 17 241 3038 170 2 125 37 16 1014 173 715 1301 336 25 31 3073 277 4312 23570 6.5 14.9 3.7 3.2 8.5 3.1 7.3 37 5 11.7 5.7 10.2 3 10.6 10.7 10.6 17.5 11.3 8.6 14.8 7.8 12.4 7.1 3.9 25.7 3.4 1 3.1 19 6 14.1 9.8 259 784 163 66 39 140 192 226 112 3590 2268 810 122 12 239 2930 196 1 134 42 17 984 190 918 1169 542 46 48 2881 245 4396 23761 6.3 14.5 4.5 3.2 9.5 2.7 7 36.5 4.2 11.4 5.7 14.9 2.6 7.5 10.5 10.2 20.7 5.6 9.5 16.5 8.2 11.9 7.7 5 23.1 5.5 1.8 4.7 17.9 5.2 14.2 9.8 263 836 123 71 49 185 146 209 111 3819 2522 968 186 13 252 3262 218 0 114 40 23 891 166 918 1129 632 44 42 3156 231 4510 25129 6.4 15.3 3.4 3.4 11.7 3.6 5.3 33.8 4.2 12.1 6.3 17.9 3.9 8.1 11.1 11.4 23.3 0 8.2 15.3 11.1 10.8 6.6 5 22.4 6.5 1.7 4.1 17 4.9 14.5 10.3 222 786 161 77 46 211 178 200 102 3701 2694 780 191 8 257 2972 203 0 125 50 30 886 158 944 1032 635 71 39 3288 223 4523 24793 5.4 14.3 4.5 3.7 10.9 4.1 6.4 32.5 3.8 11.7 6.7 14.6 4.1 5 11.3 10.3 21.9 0 9.1 18.6 14.3 10.7 6.2 5.1 20.7 6.5 2.7 3.8 14.3 4.7 14.4 9.9 184 725 202 83 49 209 196 182 138 2923 2864 615 212 9 261 2943 236 1 90 43 36 712 200 876 665 549 75 45 2851 203 4603 22980 4.4 13.2 5.7 4 11.7 4 7 29.6 5.1 9.2 7.2 11.6 4.5 5.5 11.5 10 25.7 5.4 6.6 15.6 16.9 8.5 7.8 4.8 13.4 5.6 2.8 4.4 12.5 4.2 14.5 9.2 6329 17560 1530 1040 645 1973 4972 6043 2474 42298 42654 11900 2198 228 3815 25152 4250 39 1902 996 196 18469 3818 14400 38110 11929 536 597 28161 7549 97479 399432 28 5 98 365 563 7 5 324 290 1254 399 341 0 15 36172 6 132 444 770 385 0 9521 2062 53186 1.9 11.4 6.4 8.1 12.8 0.4 0.5 16.1 7.9 16 14.8 17.4 0 4.9 54.5 39.1 3 11.5 20.2 1.1 0 45.1 15.1 29.2 55 2 115 410 621 23 0 305 297 1208 422 377 0 8 6 110 421 685 485 0 9472 15022 3.8 5 7.6 9 14.1 1.2 0 15.3 7.9 15.1 15.4 19.2 0 2.6 38.4 2.5 10.8 17.5 1.3 0 45.1 14.7 58 2 158 356 659 23 10 387 355 1169 406 375 0 13 2 119 462 517 819 0 9400 15290 4 5 10.7 7.7 14.9 1.2 1 19.6 9.3 14.4 14.6 19.1 0 4.2 12.3 2.7 11.7 12.9 2.2 0 44.9 14.7 82 4 161 329 802 21 15 362 353 1204 292 381 0 10 0 135 421 519 1077 10011 16179 5.7 10.3 11.1 7 18.2 1.1 1.5 18.6 9.1 14.6 10.3 19.4 0 3.2 0 3.1 10.5 12.7 2.9 47.9 15.4 59 3 215 375 1052 29 389 343 1337 366 451 0 17 3 109 384 565 1478 8993 16168 4.1 7.7 15.1 7.8 23.8 2.8 20.2 8.7 15.9 12.7 23 0 5.5 18.4 2.5 9.5 13.5 3.9 45.4 15.7 555 58 1349 3728 10393 201 79 3455 5558 16071 3866 5431 21 147 36172 66 2493 21765 4527 6399 1 130557 16234 269126 22147 2213 52394 76756 11.2 2.4 39.4 18.1 21846 2765 14171 38783 11 3 26.7 11.3 23159 3292 13968 40419 11.5 3.5 26.2 11.6 22668 3715 14589 40972 10.9 3.9 27.3 11.5 20904 3992 14251 39148 10.1 4.3 27.1 11.1 379749 44788 243982 668558 EU/EEA Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein Lithuania Luxembourg Malta Netherlands Norway Poland Portugal Romania Slovakia Slovenia Spain Sweden United Kingdom Total EU/EEA Non-EU/EEA Albania Andorra Armenia Azerbaijan Belarus Bosnia and Herzegovina former Yugoslav Republic of Macedonia, the Georgia Israel Kazakhstan Kyrgyzstan Moldova Monaco Montenegro Russia San Marino Serbia*** Switzerland Tajikistan Turkey Turkmenistan Ukraine Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region 37 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 3: New HIV diagnoses in females and rates per 100 000 population, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region Area Country* EU/EEA West Austria West Belgium Centre Bulgaria Centre Croatia Centre Cyprus Centre Czech Republic West Denmark East Estonia West Finland West France West Germany West Greece Centre Hungary West Iceland West Ireland West Italy East Latvia Liechtenstein East Lithuania West Luxembourg West Malta West Netherlands West Norway Centre Poland West Portugal Centre Romania Centre Slovakia Centre Slovenia West Spain West Sweden West United Kingdom Total EU/EEA Non-EU/EEA Centre Albania West Andorra East Armenia East Azerbaijan East Belarus Centre Bosnia and Herzegovina Centre former Yugoslav Republic of Macedonia, the East Georgia West Israel East Kazakhstan East Kyrgyzstan East Moldova West Monaco Centre Montenegro East Russia West San Marino Centre Serbia*** West Switzerland East Tajikistan Centre Turkey East Turkmenistan East Ukraine East Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region 2005 N Rate 2006 N Rate 2007 N Rate 2008 N Rate 2009 N 92 440 27 10 15 20 71 230 39 2297 481 130 14 3 137 423 106 0 30 24 6 294 97 174 690 274 6 3 392 167 3229 9921 2.2 8.2 0.7 0.4 4 0.4 2.6 31.6 1.5 7.1 1.1 2.3 0.3 2 6.6 4.2 8.7 0 1.7 10.3 3 3.6 4.2 0.9 12.7 2.5 0.2 0.3 4.4 3.7 10.5 4.4 84 338 20 9 14 20 71 239 57 2117 499 104 13 3 132 538 114 1 22 16 8 227 97 175 745 225 7 3 397 152 2947 9392 2 6.3 0.5 0.4 3.7 0.4 2.6 33.1 2.1 6.5 1.2 1.8 0.2 2 6.3 4.3 9.5 5.6 1.2 6.8 3.9 2.7 4.1 0.9 13.7 2.1 0.3 0.3 4.4 3.3 9.5 4.1 78 404 21 5 15 24 82 259 51 1995 449 89 10 7 149 617 126 0 32 12 6 240 82 155 731 212 7 2 589 184 2644 9277 1.8 7.5 0.5 0.2 3.9 0.5 3 36 1.9 6.1 1.1 1.6 0.2 4.6 6.9 3.9 10.5 0 1.8 5 2.9 2.9 3.5 0.8 13.4 2 0.3 0.2 4.8 4 8.5 4 90 343 21 3 13 27 81 230 42 1998 465 104 9 3 146 668 127 0 30 11 11 205 117 152 709 245 5 3 710 158 2623 9349 2.1 6.3 0.5 0.1 3.3 0.5 2.9 32.1 1.6 6 1.1 1.8 0.2 1.9 6.5 3.5 10.7 0 1.7 4.5 5.4 2.5 4.9 0.8 12.9 2.3 0.2 0.3 5 3.4 8.4 3.9 65 381 38 6 12 26 57 168 66 1843 458 96 15 9 137 944 105 0 49 17 9 207 99 160 659 219 5 8 713 149 2190 8910 1.5 6.9 1 0.3 2.9 0.5 2.1 23.5 2.4 5.6 1.1 1.7 0.3 5.7 6 3.2 9 0 2.9 6.8 4.4 2.5 4.1 0.8 12 2.1 0.2 0.8 4.3 3.2 6.9 3.5 8 1 15 34 352 5 1 66 128 266 49 217 0 0 2 16 242 22 92 0 4516 444 6476 0.5 2.7 1 0.8 6.8 0.3 0.1 2.8 3.8 3.3 1.9 10 0 0 13.2 0.3 6.4 0.6 0.3 0 18 3.4 5.5 10 1 25 26 342 2 5 77 118 451 63 249 0 2 0 15 254 49 83 0 5366 522 7660 0.7 2.7 1.7 0.6 6.7 0.1 0.5 3.3 3.4 5.6 2.4 11.5 0 0.6 0 0.3 6.7 1.4 0.2 0 21.5 3.9 6.4 14 0 32 57 450 0 1 98 116 582 115 309 0 1 0 16 222 82 101 0 5038 1082 8316 0.9 0 2.2 1.3 8.8 0 0.1 4.2 3.3 7.1 4.3 14.4 0 0.3 0 0.3 5.8 2.3 0.3 0 20.3 8 7 17 0 32 83 427 2 1 102 143 679 182 355 0 3 2 20 203 77 123 0 6582 1231 10264 1.2 0 2.2 1.9 8.4 0.1 0.1 4.5 4 8.2 6.8 16.6 0 1 12.8 0.4 5.2 2.1 0.3 0 26.6 9 8.5 19 0 53 78 510 0 0 109 120 685 182 304 0 2 0 9 180 107 126 0 7002 1807 11293 1.3 0 3.7 1.7 10 0 0 4.8 3.3 8.2 6.7 14.3 0 0.6 0 0.2 4.6 2.9 0.3 0 28.4 13 9.5 9385 665 6347 16397 5.4 0.7 8.9 4.8 8903 603 7545 17052 5 0.6 10.5 4.9 8747 584 8262 17593 4.7 0.6 11.5 5 8832 644 10137 19613 4.6 0.7 14.1 5.4 8399 645 11159 20203 4.1 0.7 15.4 5.4 * Country-specific comments are in Annex 5 ** Cumulative total is the total number of cases reported by the country since the start of reporting *** Includes data from Kosovo (without prejudice to positions on status, and in line with UNSCR 1244 and the ICJ Opinion on the Kosovo Declaration of Independence): 2005 (0), 2006 (0), 2007 (0), 2008 (0), 2009 (1), 2010 (0), 2011 (0), 2012 (1), 2013 (0), 2014 (1), cumulative 2000-2014 (12). 38 Rate HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT 2010 N Rate 2011 N Rate 2012 N Rate 2013 N Rate 2014 N Rate Cumulative Country* total** 67 402 31 3 7 21 74 146 54 1877 402 78 9 7 89 985 104 2 28 16 2 192 85 154 636 217 3 4 675 179 2036 8585 1.6 7.3 0.8 0.1 1.7 0.4 2.7 20.5 2 5.6 1 1.4 0.2 4.4 3.9 3.2 9 11 1.7 6.3 1 2.3 3.5 0.8 11.5 2.1 0.1 0.4 4 3.8 6.4 3.4 69 399 38 11 15 13 74 140 60 1824 424 143 12 11 89 959 103 0 32 14 4 167 79 160 516 242 3 7 612 146 1782 8148 1.6 7.1 1 0.5 3.5 0.2 2.6 19.7 2.2 5.4 1 2.5 0.2 6.9 3.9 3.1 9.1 0 1.9 5.4 1.9 2 3.2 0.8 9.3 2.3 0.1 0.7 3.7 3.1 5.6 3.2 63 392 34 3 9 27 54 106 45 1827 454 174 14 6 97 882 121 0 46 16 7 171 76 159 478 238 6 3 576 149 1736 7969 1.5 6.9 0.9 0.1 2 0.5 1.9 15 1.6 5.4 1.1 3.1 0.3 3.8 4.2 2.9 10.9 0 2.8 6.1 3.3 2 3.1 0.8 8.7 2.3 0.2 0.3 3 3.1 5.4 3.1 43 339 39 8 8 24 55 125 55 1802 592 84 17 3 86 839 137 0 52 11 6 128 75 146 432 263 12 5 577 130 1500 7593 1 6 1 0.4 1.8 0.4 1.9 17.8 2 5.3 1.4 1.5 0.3 1.9 3.7 2.7 12.5 0 3.2 4.1 2.8 1.5 3 0.7 7.9 2.6 0.4 0.5 2.4 2.7 4.6 2.9 51 314 45 9 7 23 60 109 43 1386 659 98 20 2 98 752 111 0 51 26 4 119 68 171 255 242 11 3 513 146 1536 6932 1.2 5.5 1.2 0.4 1.6 0.4 2.1 15.6 1.6 4.1 1.6 1.7 0.4 1.2 4.2 2.4 10.2 0 3.2 9.5 1.9 1.4 2.7 0.9 4.7 2.4 0.4 0.3 2.2 3 4.7 2.6 2082 10053 460 166 258 381 1855 2934 925 23484 10300 2495 296 93 2206 8112 1964 23 476 349 67 4607 1820 3781 14574 8607 89 85 6526 3580 42256 154926 15 0 51 94 506 0 0 133 134 733 168 362 0 0 26409 0 16 160 225 139 0 6915 1733 37793 1 0 3.5 2 10 0 0 6 3.6 8.7 6.1 17.1 0 0 34.4 0 0.3 4 6 0.4 0 28.2 12.3 19.2 23 0 67 138 575 4 0 124 152 791 192 344 0 1 2 17 132 293 167 0 7697 10719 1.6 0 4.6 3 11.3 0.2 0 5.6 4 9.2 6.8 16.3 0 0.3 12.3 0.4 3.3 7.6 0.4 0 31.5 9.9 23 0 70 161 564 2 4 147 132 842 295 382 0 1 3 11 150 332 250 0 7301 10670 1.6 0 4.7 3.4 11.1 0.1 0.4 6.8 3.4 9.7 10.3 18.1 0 0.3 17.5 0.2 3.7 8.4 0.7 0 30 9.6 37 1 77 185 731 6 0 118 120 936 211 325 0 0 1 13 151 374 242 7722 11250 2.6 2.7 5 3.9 14.4 0.3 0 5.5 3 10.6 7.3 15.4 0 0 5.8 0.3 3.7 9.3 0.6 31.8 10.2 18 0 117 229 759 0 147 133 1013 279 380 0 3 0 17 123 420 334 6683 10655 1.2 0 7.4 4.7 14.9 0 7 3.3 11.3 9.4 18 0 0.9 0 0.4 3 10.3 0.8 29.1 9.8 225 13 604 1174 7129 46 16 1240 2799 8061 1823 3922 13 28 26409 19 682 9984 2031 2188 1 87064 7783 163254 8150 619 37607 46378 3.9 0.7 25.2 10.3 7658 713 10496 18867 3.7 0.7 17.9 5.2 7488 784 10367 18639 3.6 0.8 17.6 5.1 7030 820 10993 18843 3.3 0.8 18.6 5.1 6386 903 10298 17587 3 0.9 17.7 4.7 148212 17329 152616 318180 EU/EEA Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein Lithuania Luxembourg Malta Netherlands Norway Poland Portugal Romania Slovakia Slovenia Spain Sweden United Kingdom Total EU/EEA Non-EU/EEA Albania Andorra Armenia Azerbaijan Belarus Bosnia and Herzegovina former Yugoslav Republic of Macedonia, the Georgia Israel Kazakhstan Kyrgyzstan Moldova Monaco Montenegro Russia San Marino Serbia*** Switzerland Tajikistan Turkey Turkmenistan Ukraine Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region 39 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 4: New HIV diagnoses in men infected through sex with men, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region Area EU/EEA West West Centre Centre Centre Centre West East West West West West Centre West West West East Country* Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein East Lithuania West Luxembourg West Malta West Netherlands West Norway Centre Poland West Portugal Centre Romania Centre Slovakia Centre Slovenia West Spain West Sweden West United Kingdom Total EU/EEA Non-EU/EEA Centre Albania West Andorra East Armenia East Azerbaijan East Belarus Centre Bosnia and Herzegovina Centre former Yugoslav Republic of Macedonia, the East Georgia West Israel East Kazakhstan East Kyrgyzstan East Moldova West Monaco Centre Montenegro East Russia*** West San Marino Centre Serbia**** West Switzerland East Tajikistan Centre Turkey East Turkmenistan East Ukraine East Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region Year of diagnosis 2009 2010 2011 2012 2013 2014 Cumulative total** 161 402 32 60 22 129 112 0 48 1505 1595 373 126 5 134 1267 18 0 7 23 6 771 85 162 454 65 21 28 1838 115 2728 12292 165 407 47 49 27 113 113 0 36 1423 1480 337 106 0 145 1279 20 0 9 29 4 753 97 314 465 103 32 35 1803 94 2844 12329 158 398 59 65 31 152 82 1 47 1612 1709 328 149 1 173 1578 18 0 11 27 8 694 76 346 486 90 28 33 1935 116 3057 13468 137 425 72 70 35 179 116 6 43 1584 1752 335 163 0 155 1507 27 0 30 29 16 709 98 272 433 94 58 27 2003 111 3028 13514 111 335 97 68 39 169 132 3 55 1136 1904 332 171 0 174 1513 28 1 11 21 25 555 115 236 283 125 53 33 1815 89 3048 12677 3074 6766 421 714 360 1526 2793 103 1074 16618 25215 6726 1656 105 2092 10910 313 3 169 523 78 13275 1836 2265 8264 764 397 431 16058 3675 62807 191011 6 1 5 2 9 3 3 7 142 20 0 12 0 6 0 84 250 0 3 0 94 1 648 5 3 0 7 14 4 5 26 147 22 0 6 0 11 0 0 81 245 0 32 0 90 0 698 15 1 4 5 29 12 1 25 151 27 0 5 0 5 4 66 210 0 0 0 143 703 9 1 4 12 31 21 7 43 155 24 3 4 0 8 0 84 227 0 0 0 152 785 11 3 13 11 41 13 13 67 163 40 14 4 0 6 0 94 195 0 189 262 1139 8 3 10 11 53 26 63 146 44 17 9 0 13 0 76 215 6 272 277 1249 90 27 47 63 215 79 62 281 2018 231 36 58 14 82 0 21 972 5516 6 681 0 1241 29 11769 11719 581 173 12473 12017 783 190 12990 11840 925 267 13032 12868 1082 303 14253 12842 1296 515 14653 12007 1386 532 13926 189485 10500 2792 202780 2005 2006 2007 2008 101 256 4 34 14 53 120 0 32 1375 1251 248 56 3 60 363 14 0 3 9 4 639 56 46 305 25 9 31 548 107 2642 8408 135 299 10 37 7 56 100 0 62 1360 1388 251 40 2 89 536 15 0 9 17 7 670 90 51 355 20 14 25 623 102 2600 8970 133 299 24 30 19 77 142 0 72 1455 1559 299 63 0 91 595 15 0 4 19 0 770 77 38 338 15 25 30 1257 124 2819 10389 164 368 17 52 9 93 133 0 49 1495 1578 324 93 2 105 716 21 0 9 29 0 855 92 62 437 49 33 34 1639 119 2655 11232 144 378 28 42 9 107 108 0 43 1432 1652 335 87 2 138 1183 14 0 9 26 4 772 87 80 416 59 35 29 1724 122 2760 11825 3 3 2 0 2 3 0 8 92 3 0 5 0 4 0 43 223 0 25 0 20 10 446 0 0 2 3 1 5 2 4 78 10 1 2 0 4 0 45 263 0 29 0 35 0 484 1 3 2 3 4 0 3 11 123 10 1 0 1 5 0 40 270 0 25 0 48 0 550 7 3 3 2 5 1 0 6 125 13 0 2 0 8 0 66 264 0 0 0 65 0 570 8437 350 67 8854 9027 345 82 9454 10446 395 98 10939 11152 524 126 11802 * Country-specific comments are in Annex 5 ** Cumulative total is the total number of cases reported by the country since the start of reporting *** No official data were reported by Russia. Information about new and cumulative HIV diagnoses by mode of transmission were obtained from the Federal Scientific and Methodological Center for Prevention and Control of AIDS: 2005 (178), 2006 (137), 2007 (203), 2008 (278), 2009 (364), 2010 (357), 2011 (380), 2012 (296), 2013 (371), cumulative as of 31 December 2013 (3647). Reference: HIV-infection bulletin number 39, available from http://hivrussia.org/files/bul_39. pdf. **** Includes data from Kosovo (without prejudice to positions on status, and in line with UNSCR 1244 and the ICJ Opinion on the Kosovo Declaration of Independence): 2005 (0), 2006 (0), 2007 (1), 2008 (3), 2009 (0), 2010 (0), 2011 (0), 2012 (1), 2013 (1), 2014 (4), cumulative 2000-2014 (10). 40 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 5: New HIV diagnoses in people infected through injecting drug use, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region Area EU/EEA West West Centre Centre Centre Centre West East West West West West Centre West West West East Country* Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein East Lithuania West Luxembourg West Malta West Netherlands West Norway Centre Poland West Portugal Centre Romania Centre Slovakia Centre Slovenia West Spain West Sweden West United Kingdom Total EU/EEA Non-EU/EEA Centre Albania West Andorra East Armenia East Azerbaijan East Belarus Centre Bosnia and Herzegovina Centre former Yugoslav Republic of Macedonia, the East Georgia West Israel East Kazakhstan East Kyrgyzstan East Moldova West Monaco Centre Montenegro East Russia*** West San Marino Centre Serbia**** West Switzerland East Tajikistan Centre Turkey East Turkmenistan East Ukraine East Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region Year of diagnosis 2009 2010 2011 2012 2013 2014 Cumulative total** 35 15 56 2 0 5 8 62 8 126 81 25 0 9 23 265 86 0 107 1 0 7 11 44 228 22 2 0 243 24 154 1649 37 17 63 4 0 9 10 69 8 119 77 311 0 12 18 186 90 1 87 1 0 6 10 66 138 171 1 0 225 13 130 1879 39 14 40 1 0 6 11 72 7 127 82 518 0 3 16 212 94 0 64 4 0 7 11 43 128 282 1 1 193 17 118 2111 23 17 33 0 0 6 13 72 3 103 101 260 1 1 22 178 77 0 64 5 3 6 8 39 94 275 0 2 159 8 127 1700 21 11 46 0 3 10 11 67 7 64 111 102 1 1 25 141 74 0 38 16 0 0 7 37 40 154 1 2 115 8 131 1244 1729 864 474 65 12 104 530 3950 381 1728 3438 1567 24 53 1563 2183 3117 5 1510 157 9 761 611 6079 18539 976 13 18 3028 1200 5947 60635 1 0 46 292 212 0 0 225 42 1230 466 62 0 0 0 9 26 263 1 0 7105 612 10592 0 0 49 273 223 0 0 216 41 1081 347 59 0 0 0 0 6 20 672 0 0 6934 1850 11771 0 0 41 319 254 0 0 190 42 903 355 61 0 0 0 9 21 455 5 0 6588 9243 1 0 44 217 247 0 0 230 71 774 255 40 0 1 0 5 24 299 6 0 5933 8147 0 0 32 204 201 1 0 168 71 719 188 20 0 0 0 11 13 243 4 5847 7722 1 0 42 183 376 0 171 38 772 181 62 0 0 0 5 7 236 10 4670 6754 5 13 546 2635 6937 22 2 2315 1151 13866 3147 2763 8 5 0 11 971 3767 3120 109 0 109885 11390 162668 1466 169 10794 12429 1324 137 11959 13420 1381 328 9412 11122 1602 387 8269 10258 1215 372 7835 9422 856 270 6872 7998 49238 8879 165181 223303 2005 2006 2007 2008 62 14 12 3 1 4 17 192 16 186 134 20 2 0 67 149 115 0 85 7 0 17 20 160 599 2 0 0 309 20 186 2399 41 19 34 3 0 5 10 191 10 173 150 14 0 1 59 187 108 0 62 3 3 15 7 126 522 10 1 0 278 34 196 2262 56 21 43 2 2 12 21 115 12 154 143 13 3 1 55 184 141 0 59 6 0 13 13 99 410 12 1 0 261 62 174 2088 40 18 54 1 1 8 13 36 7 142 115 9 2 0 40 212 100 0 44 5 2 8 12 55 396 6 3 0 279 23 175 1806 29 14 74 0 0 4 14 85 13 129 92 15 0 5 30 277 78 0 118 0 0 7 11 62 282 17 1 0 299 25 156 1837 0 0 46 108 276 2 0 129 61 664 103 228 0 0 0 11 74 179 6 0 6270 1120 9277 0 0 24 172 242 1 1 155 49 1208 168 236 1 1 0 8 56 125 5 0 7127 1454 11033 1 0 32 318 298 0 0 184 40 1292 254 224 0 0 0 12 50 209 5 0 7084 1816 11819 0 0 36 286 195 0 0 200 41 1475 294 136 0 0 0 10 30 206 0 0 7009 1561 11479 1958 203 9515 11676 1828 195 11272 13295 1689 192 12026 13907 1567 140 11578 13285 * Country-specific comments are in Annex 5 ** Cumulative total is the total number of cases reported by the country since the start of reporting *** No official data were reported by Russia. Information about new and cumulative HIV diagnoses by mode of transmission were obtained from the Federal Scientific and Methodological Center for Prevention and Control of AIDS: 2005 (10 988), 2006 (11 893), 2007 (12 429), 2008 (16 689), 2009 (16 009), 2010 (16 308), 2011 (16 937), 2012 (18 029), 2013 (19 875), cumulative as of 31 December 2013 (299 923). Reference: HIV-infection bulletin number 39, available from http://hivrussia.org/files/bul_39.pdf. **** Includes data from Kosovo (without prejudice to positions on status, and in line with UNSCR 1244 and the ICJ Opinion on the Kosovo Declaration of Independence): 2005 (0), 2006 (0), 2007 (0), 2008 (0), 2009 (1), 2010 (0), 2011 (0), 2012 (0), 2013 (0), 2014 (0), cumulative 2000-2014 (2). 41 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 6: New HIV diagnoses in people infected through heterosexual contact, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region Area EU/EEA West West Centre Centre Centre Centre West East West West West West Centre West West West East Country* Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein East Lithuania West Luxembourg West Malta West Netherlands West Norway Centre Poland West Portugal Centre Romania Centre Slovakia Centre Slovenia West Spain West Sweden West United Kingdom Total EU/EEA Non-EU/EEA Centre Albania West Andorra East Armenia East Azerbaijan East Belarus Centre Bosnia and Herzegovina Centre former Yugoslav Republic of Macedonia, the East Georgia West Israel East Kazakhstan East Kyrgyzstan East Moldova West Monaco Centre Montenegro East Russia*** West San Marino Centre Serbia**** West Switzerland East Tajikistan Centre Turkey East Turkmenistan East Ukraine East Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region Year of diagnosis 2009 2010 2011 2012 2013 2014 Cumulative total** 110 438 71 7 15 38 141 71 94 2198 450 118 18 10 127 1880 131 3 29 28 10 345 157 101 1190 279 4 7 1232 238 2995 12535 107 439 89 22 23 25 132 56 88 2039 517 147 19 6 126 1811 144 0 34 26 13 298 155 91 1046 313 12 8 1071 222 2830 11909 112 460 58 7 23 41 96 127 71 2160 485 149 24 0 134 1764 112 0 50 25 15 291 142 98 963 323 14 4 1096 198 2606 11648 86 385 70 13 16 44 90 169 67 2084 598 114 24 0 134 1690 125 0 51 23 10 232 123 82 898 336 21 7 1075 167 2223 10957 82 360 96 11 10 45 102 162 70 1443 780 127 28 0 119 1598 132 0 66 27 9 209 141 88 560 320 18 4 875 166 2185 9833 2874 10891 1108 348 481 603 3024 964 1360 27718 11905 3084 416 100 2849 15161 1619 12 456 546 129 7075 2948 1353 23923 4974 151 108 11732 4969 61713 204595 52 1 83 116 823 3 2 147 177 750 173 574 0 6 0 23 253 165 218 0 8541 955 13062 34 2 86 130 789 3 0 201 209 819 186 606 0 3 0 35 222 296 203 0 9122 852 13798 60 1 127 190 881 14 0 203 208 1010 181 613 0 4 4 37 211 437 251 0 10248 14680 66 1 161 243 919 4 7 244 203 1138 307 664 0 5 3 27 219 392 377 0 10440 15420 100 1 176 270 1265 12 2 237 185 1273 276 325 0 1 0 20 221 518 431 11472 16785 61 0 262 359 1349 4 292 192 1399 389 620 0 4 0 31 167 569 485 10648 16831 628 21 1224 1736 9954 126 31 1952 4296 8850 2020 5702 11 67 0 23 736 7306 2792 3612 0 101160 4711 156958 12624 852 12514 25991 12194 818 13318 26333 11497 968 14124 26589 11193 1078 14797 27068 10406 1179 16157 27742 9212 1205 16247 26664 203658 14742 143141 361553 2005 2006 2007 2008 159 467 65 26 25 29 110 0 67 2812 559 175 20 5 172 665 96 0 21 38 9 467 134 90 1263 268 12 2 696 208 4768 13428 140 420 46 15 27 25 127 0 93 2420 533 152 15 7 182 910 87 1 16 32 10 374 164 74 1335 220 8 3 748 201 4313 12698 139 441 58 15 21 28 130 0 74 2322 481 131 15 0 167 1059 127 0 28 20 12 372 141 72 1369 238 12 2 1063 228 3993 12758 148 402 52 15 22 44 122 3 59 2484 515 160 17 6 190 1153 164 0 28 25 24 360 185 62 1349 267 8 4 1251 207 3880 13206 122 425 68 12 27 43 105 17 91 2259 509 121 23 8 166 1852 133 1 37 28 9 343 170 76 1281 284 9 6 1228 209 3267 12929 24 2 25 63 428 8 0 81 177 247 58 291 0 5 0 25 364 39 158 0 4586 364 6945 30 1 38 41 464 4 5 112 187 334 71 366 0 2 1 24 340 70 153 0 5646 495 8384 36 1 70 77 657 4 2 125 176 504 107 500 0 4 0 23 295 123 295 0 5736 701 9436 43 0 86 100 656 8 3 132 201 682 162 588 0 2 0 28 279 142 275 0 7780 716 11883 13317 757 6299 20373 12690 651 7740 21082 12614 825 8755 22194 13000 850 11239 25089 * Country-specific comments are in Annex 5 ** Cumulative total is the total number of cases reported by the country since the start of reporting *** No official data were reported by Russia. Information about new and cumulative HIV diagnoses by mode of transmission were obtained from the Federal Scientific and Methodological Center for Prevention and Control of AIDS: 2005 (5653), 2006 (6329), 2007 (7255), 2008 (9910), 2009 (10 526), 2010 (12 230), 2011 (12 785), 2012 (14 038), 2013 (15 604), cumulative as of 31 December 2013 (117 389). Reference: HIV-infection bulletin number 39, available from http://hivrussia. org/files/bul_39.pdf. **** Includes data from Kosovo (without prejudice to positions on status, and in line with UNSCR 1244 and the ICJ Opinion on the Kosovo Declaration of Independence): 2005 (0), 2006 (2), 2007 (0), 2008 (0), 2009 (3), 2010 (0), 2011 (3), 2012 (1), 2013 (1), 2014 (2), cumulative 2000-2014 (31). 42 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 7: New HIV diagnoses in people infected through mother-to-child transmission, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region Area EU/EEA West West Centre Centre Centre Centre West East West West West West Centre West West West East Country* Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein East Lithuania West Luxembourg West Malta West Netherlands West Norway Centre Poland West Portugal Centre Romania Centre Slovakia Centre Slovenia West Spain West Sweden West United Kingdom Total EU/EEA Non-EU/EEA Centre Albania West Andorra East Armenia East Azerbaijan East Belarus Centre Bosnia and Herzegovina Centre former Yugoslav Republic of Macedonia, the East Georgia West Israel East Kazakhstan East Kyrgyzstan East Moldova West Monaco Centre Montenegro East Russia*** West San Marino Centre Serbia**** West Switzerland East Tajikistan Centre Turkey East Turkmenistan East Ukraine East Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region Year of diagnosis 2009 2010 2011 2012 2013 2014 Cumulative total** 1 7 4 0 0 0 3 2 1 41 20 3 0 0 9 12 4 0 0 0 0 23 1 11 17 27 0 0 15 16 105 322 2 10 2 1 0 0 3 2 1 35 15 4 0 0 3 24 2 0 1 0 0 9 4 7 9 22 0 1 11 13 107 288 0 8 0 0 1 2 4 4 2 50 20 0 1 0 5 13 7 0 0 1 0 12 7 4 5 19 0 0 7 8 78 258 1 5 5 0 0 0 5 2 2 31 21 0 1 0 3 9 10 0 1 0 0 4 1 4 10 23 0 0 12 3 90 243 1 7 1 1 0 1 5 5 2 29 25 1 1 0 2 12 4 0 2 2 0 4 3 2 6 18 0 0 2 3 97 236 56 437 20 14 3 7 101 51 26 425 361 65 12 1 77 131 63 1 5 10 0 297 79 195 426 701 0 7 97 206 2504 6378 2 0 3 5 15 0 0 4 10 22 16 8 0 0 0 2 4 11 7 0 169 96 374 0 0 3 11 22 0 0 13 7 21 19 10 0 0 0 0 0 7 14 0 0 177 73 377 3 0 2 9 23 0 0 7 8 18 20 16 0 0 0 1 4 26 4 0 136 277 3 0 3 14 16 0 0 9 7 30 33 9 0 0 0 0 2 39 12 0 149 326 6 0 5 10 16 0 0 3 9 36 10 13 0 0 0 4 3 46 11 127 299 3 0 7 18 15 0 5 9 22 15 19 0 0 0 1 1 55 22 122 314 30 1 35 83 245 1 2 86 240 265 150 141 1 4 0 1 46 191 203 104 0 1905 363 4097 261 49 354 664 288 42 369 699 262 41 262 565 229 42 313 584 209 54 279 542 211 50 289 550 5733 1146 3595 10475 2005 2006 2007 2008 1 8 1 0 1 0 3 4 1 39 24 2 2 0 3 9 2 0 0 1 0 15 5 7 9 24 0 0 4 12 136 313 2 6 0 1 0 0 2 4 1 28 19 3 0 0 2 5 5 0 0 0 0 9 6 25 12 20 0 0 4 9 137 300 4 19 1 1 0 0 7 2 0 38 27 3 2 0 6 5 8 0 1 0 0 13 9 16 18 8 0 0 11 8 118 325 1 8 0 1 0 0 4 8 1 29 16 1 0 0 7 5 8 0 0 0 0 23 4 13 16 14 0 0 10 17 102 288 2 4 1 0 0 0 0 3 2 34 11 0 2 0 5 7 2 0 0 1 0 18 4 12 15 23 0 0 13 11 120 290 0 0 2 3 34 0 1 7 16 9 2 9 0 0 0 1 5 0 5 0 192 11 297 3 0 4 1 19 1 0 6 13 20 2 14 0 1 0 0 1 1 3 0 200 31 320 4 0 3 3 25 0 0 15 11 30 8 7 0 0 0 1 7 8 3 0 230 84 439 1 0 0 5 17 0 0 12 16 44 25 17 0 1 0 1 2 3 8 0 217 57 426 293 42 275 610 259 54 307 620 304 36 424 764 262 39 413 714 * Country-specific comments are in Annex 5 ** Cumulative total is the total number of cases reported by the country since the start of reporting *** No official data were reported by Russia. Information about new and cumulative HIV diagnoses by mode of transmission were obtained from the Federal Scientific and Methodological Center for Prevention and Control of AIDS: 2005 (549), 2006 (581), 2007 (523), 2008 (621), 2009 (557), 2010 (494), 2011 (487), 2012 (446), 2013 (366), cumulative as of 31 December 2013 (5964). Reference: HIV-infection bulletin number 39, available from http://hivrussia.org/files/bul_39.pdf. **** Includes data from Kosovo (without prejudice to positions on status, and in line with UNSCR 1244 and the ICJ Opinion on the Kosovo Declaration of Independence): 2005 (0), 2006 (0), 2007 (0), 2008 (0), 2009 (2), 2010 (0), 2011 (0), 2012 (0), 2013 (0), 2014 (0), cumulative 2000-2014 (2). 43 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 8: New HIV diagnoses*, by sex, transmission mode and year of diagnosis (2005–2014) and cumulative totals Table 8a: EU/EEA and non-EU/EEA countries Transmission mode EU/EEA Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total EU/EEA Non-EU/EEA Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total non-EU/EEA Total WHO European Region Transmission mode EU/EEA Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total EU/EEA Non-EU/EEA Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total non-EU/EEA Total WHO European Region * Female 2005 Male Total** Female 2006 Male Total** Female 2007 Male Total** Female 2008 Male Total** 312 7008 148 72 15 1147 8702 7449 1272 4952 140 50 9 2027 15899 7451 1589 11977 289 122 24 3207 24659 324 6372 137 49 11 1152 8045 7750 1152 4583 125 49 7 2156 15822 7760 1480 10966 262 98 18 3343 23927 324 5972 168 38 14 1141 7657 8479 1101 4577 122 35 14 2306 16634 8499 1429 10564 291 73 28 3481 24365 248 6003 126 33 12 1167 7589 8793 974 4720 126 27 9 2438 17087 8815 1224 10737 252 61 21 3645 24755 1621 4039 39 13 1 220 5933 14635 408 6528 2376 50 5 3 347 9717 25616 408 8149 6415 281 18 4 572 15847 40506 1834 4868 41 9 24 277 7053 15097 449 7739 2863 44 8 51 386 11540 27361 450 9573 7731 285 17 75 674 18805 42730 1899 4878 57 6 33 260 7133 14790 523 8093 3556 65 6 56 396 12695 29329 525 9998 8436 352 12 89 671 20083 44448 1764 6742 67 1 38 294 8906 16495 569 8109 4138 75 8 36 489 13424 30511 569 9918 10884 361 9 86 796 22623 47378 Female 2013 Male Total** Female 2014 Male Total** Female Cumulative total*** Male Unkown Total 229 4283 110 30 6 1248 5906 9704 1023 3657 105 31 10 2859 17389 9726 1252 7941 216 61 16 4142 23354 197 3767 101 28 7 1287 5387 9095 687 3342 113 32 14 2844 16128 9110 884 7110 215 61 21 4177 21579 0 9890 96627 3002 2237 3068 18748 133572 161525 34689 78232 2880 4402 3977 39967 325673 150 816 524 22 108 0 1293 2913 161675 45395 175383 5904 6747 7045 60008 462158 1311 9244 71 6 4 365 11001 16907 937 6406 7098 90 5 11 534 15081 32470 937 7717 16342 288 11 15 903 26213 49567 1119 8826 80 4 7 285 10321 15708 975 5625 7519 92 2 8 466 14687 30813 977 6744 16346 292 6 15 758 25138 46715 0 30765 86392 771 180 200 8091 126399 259948 10762 119537 61690 923 270 292 15491 208965 534598 204 929 407 1934 105 13 2952 6544 9454 10966 151231 148489 3628 555 505 26534 341908 804000 Data from Bosnia and Herzegovina, Russia, Turkmenistan and Uzbekistan excluded due to inconsistent reporting during the period; data from Estonia, Poland and Turkey excluded due to incomplete reporting on transmission mode during the period; data from Italy and Spain excluded due to increasing national coverage over the period. Therefore, totals by transmission mode, gender and overall may data from totals presented in Tables 1-7. ** Annual totals include people diagnosed whose gender was unknown *** Cumulative total is the total number of cases reported by country since the start of reporting 44 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Female 2009 Male Total** Female 2010 Male Total** Female 2011 Male Total** Female 2012 Male Total** 241 5393 146 27 8 1110 6925 8819 870 4357 109 29 12 2383 16579 8838 1114 9756 255 56 20 3521 23560 212 5089 160 44 10 1110 6625 9014 823 4157 122 27 12 2359 16514 9025 1035 9251 282 71 22 3509 23195 263 4722 129 33 8 1122 6277 8931 1070 4155 112 22 6 2510 16806 8933 1333 8880 244 55 14 3664 23123 320 4618 115 35 6 1152 6246 9584 1271 3945 115 32 4 2633 17584 9608 1591 8563 230 67 10 3810 23879 1759 7277 32 7 16 269 9360 16285 641 8220 4609 70 5 25 398 13968 30546 641 9979 11886 271 12 41 681 23511 47070 1713 7525 49 4 7 214 9512 16135 662 8208 5215 78 1 9 381 14554 31066 662 9921 12740 304 5 16 600 24248 47439 1791 8463 65 2 23 202 10546 16823 686 7447 5948 71 6 32 318 14508 31313 687 9238 14411 273 8 55 526 25198 48320 1427 8643 79 6 39 221 10415 16661 763 6714 6392 86 3 57 431 14446 32030 764 8141 15036 314 9 96 660 25020 48899 Transmission mode EU/EEA Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total EU/EEA Non-EU/EEA Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total non-EU/EEA Total WHO European Region 45 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 8: New HIV diagnoses*, by sex, transmission group and year of diagnosis (2005–2014) and cumulative totals Table 8b: West, Centre and East of the WHO European Region Transmission mode West Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total West Centre Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total Centre East Men who have sex with men Female 2005 Male Total** Female 2006 Male Total** Female 2007 Male Total** Female 2008 Male Total** 310 7035 138 63 10 1012 8568 7524 1185 4904 141 41 2 1865 15662 7526 1500 11956 280 104 12 2903 24281 311 6440 134 44 10 1031 7970 7858 1048 4580 116 45 6 2045 15698 7868 1363 11031 250 89 16 3100 23717 292 5976 166 41 12 1054 7541 8574 948 4500 121 35 12 2224 16414 8594 1244 10492 288 76 24 3303 24021 227 5979 127 34 11 1074 7452 8775 847 4602 120 29 8 2378 16759 8797 1076 10596 247 64 19 3475 24274 5 215 19 15 5 135 394 276 30 286 11 12 7 161 783 276 35 501 30 27 12 308 1189 8 193 9 10 1 122 343 259 55 227 16 7 1 117 682 260 63 420 25 17 2 258 1045 16 188 11 1 2 110 328 330 72 266 6 3 2 134 813 332 88 454 17 4 4 265 1164 7 220 9 0 1 130 367 461 78 285 9 2 1 144 980 461 85 505 18 2 2 300 1373 - 57 57 - 82 82 - 98 98 - 126 126 Injecting drug use 1618 6585 8203 1839 7788 9627 1915 8174 10095 1778 8158 9981 Heterosexual contact 3797 2138 5935 4606 2639 7245 4686 3367 8054 6546 3971 10520 30 38 260 35 37 272 48 60 338 57 72 348 Haemophiliac/transfusion recipient 7 2 9 4 5 9 2 3 5 0 4 4 Nosocomial infection 1 3 4 24 51 75 33 56 89 38 36 86 Mother-to-child Other/undetermined Total East Total WHO European Region Transmission mode West Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total West Centre Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total Centre East Men who have sex with men 220 348 568 276 379 658 237 344 584 257 405 666 5673 9171 15036 6784 10981 17968 6921 12102 19263 8676 12772 21731 14635 25616 40506 15097 27361 42730 14790 29329 44448 16495 30511 47378 Female 2013 Male Total** Female 2014 Male Total** Female Cumulative total*** Male Unkown Total 160 4167 93 33 6 1154 5613 9310 718 3473 94 34 9 2770 16408 9332 878 7641 188 67 15 3931 22052 147 3641 95 31 6 1201 5121 8663 453 3096 101 33 13 2747 15107 8679 600 6739 197 65 19 3961 20261 0 10126 98139 2851 1410 137 20892 133555 162345 33065 78050 2630 3270 142 46867 326370 151 825 553 23 108 0 3718 5378 162496 44016 176742 5504 4788 279 71477 465303 60 257 18 0 0 91 426 822 268 397 21 0 1 164 1673 822 328 654 39 0 1 287 2131 35 244 13 0 1 105 398 877 188 388 13 0 1 171 1638 878 223 632 26 0 2 316 2077 0 369 3971 363 970 2931 2301 10905 7279 1563 5343 456 1361 3835 2863 22700 203 832 340 27 103 0 474 1979 7482 2764 9654 846 2434 6766 5638 35584 - 509 509 - 529 529 0 2660 0 2660 Injecting drug use 1320 6443 7763 1134 5671 6805 30157 119596 88 149841 Heterosexual contact 9103 6885 15988 8708 7377 16085 80906 56520 38 137464 70 80 277 73 91 284 559 716 1906 3181 Haemophiliac/transfusion recipient 3 2 5 1 1 2 37 41 2 80 Nosocomial infection 4 11 15 7 8 15 200 292 13 505 Mother-to-child Other/undetermined 368 459 827 266 392 658 3629 5704 50 9383 Total East 10868 14389 25384 10189 14069 24378 115488 185529 2097 303114 Total WHO European Region 16907 32470 49567 15708 30813 46715 259948 534598 9454 804000 * Data from Bosnia and Herzegovina, Russia, Turkmenistan and Uzbekistan excluded due to inconsistent reporting during the period; data from Estonia, Poland and Turkey excluded due to incomplete reporting on transmission mode during the period; data from Italy and Spain excluded due to increasing national coverage over the period. Therefore, totals by transmission mode, gender and overall may differ from totals presented in Tables 1-7. ** Annual totals include people diagnosed whose gender was unknown *** Cumulative total is the total number of cases reported by country since the start of reporting 46 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Female 2009 Male Total** Female 2010 Male Total** Female 2011 Male Total** Female 2012 Male Total** 206 5303 136 32 8 1057 6742 8793 681 4235 105 32 12 2290 16148 8812 890 9544 241 64 20 3365 22936 192 5048 147 48 9 1046 6490 8901 624 4029 114 27 12 2323 16030 8912 816 9082 261 75 21 3379 22546 202 4666 123 32 8 1054 6085 8752 768 3942 100 25 5 2437 16029 8754 970 8611 227 57 13 3501 22133 221 4561 104 35 5 1101 6027 9331 976 3768 105 33 4 2522 16739 9355 1197 8330 209 68 9 3637 22805 17 240 18 0 0 84 359 495 89 315 12 1 0 139 1051 495 106 555 30 1 0 239 1426 10 204 18 0 1 93 326 585 83 307 13 1 0 117 1106 585 93 511 31 1 1 241 1463 49 226 13 2 0 92 382 598 208 386 17 1 1 128 1339 599 257 612 30 3 1 248 1750 75 215 14 1 1 67 373 714 263 384 12 0 0 159 1532 715 338 599 26 1 1 245 1925 - 172 172 - 190 190 - 267 267 - 302 1777 8320 10097 1723 8324 10047 1803 7540 9343 1451 6746 7127 4415 11542 7361 5034 12395 8293 5775 14068 8485 6185 24 62 255 44 73 294 58 66 260 76 84 2 1 3 0 0 0 1 2 3 5 2 16 25 41 7 9 16 23 32 55 39 57 302 Transmission mode West Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total West Centre Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total Centre East Men who have sex with men 8197 Injecting drug use 14670 Heterosexual contact 309 Mother-to-child 7 Haemophiliac/transfusion recipient 96 Nosocomial infection 238 352 598 184 300 488 178 263 441 205 383 9184 13347 22708 9319 13930 23430 10356 13945 24437 10261 13759 24169 Total East 588 Other/undetermined 16285 30546 47070 16135 31066 47439 16823 31313 48320 16661 32030 48899 Total WHO European Region 47 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 9: New HIV diagnoses*, by sex, age and year of diagnosis (2005–2014) and cumulative totals Table 9a: EU/EEA and non-EU/EEA countries Age category EU/EEA <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown Total EU/EEA Non-EU/EEA <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown Total non-EU/EEA Total WHO European Region Age category EU/EEA <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown Total EU/EEA Non-EU/EEA <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown Female 2005 Male Total** Female 2006 Male Total** Female 2007 Male Total** Female 2008 Male Total** 173 432 1131 1941 3146 1359 770 154 9106 171 351 1226 2395 6124 3989 2223 323 16802 346 784 2360 4353 9285 5357 3000 500 25985 174 366 935 1718 3017 1313 774 162 8459 159 288 1204 2383 6094 4193 2194 343 16858 333 654 2144 4115 9140 5516 2969 535 25406 182 341 939 1617 2851 1384 741 16 8071 137 285 1428 2662 6133 4377 2476 85 17583 321 628 2376 4308 9023 5785 3225 139 25805 145 306 856 1498 2803 1451 890 22 7971 150 313 1452 2654 6040 4728 2601 79 18017 295 622 2323 4169 8892 6193 3492 153 26139 60 401 278 293 1704 560 147 2582 68 159 317 609 3876 1597 378 2892 320 560 595 902 5580 2158 526 5477 73 395 327 379 2136 747 198 2881 109 167 370 719 4822 1964 481 3101 382 563 697 1099 6958 2713 679 5990 109 445 444 534 2532 866 267 2037 141 125 512 955 5483 2319 610 2798 480 570 958 1490 8021 3187 877 4849 123 400 1813 2334 2932 1064 349 14 133 98 1098 2992 6018 2617 719 22 487 500 2914 5335 8974 3689 1071 49 6025 9896 16118 7136 11733 19081 7234 12943 20432 9029 13697 23019 16397 30752 47423 17051 33153 50505 17593 36437 54436 19613 38128 58185 Female 2013 Male Total** Female 2014 Male Total** Female Cumulative total*** Male Unkown Total 97 197 556 945 2106 1293 974 9 6177 95 295 1820 2948 5910 4347 3084 34 18533 193 493 2380 3898 8027 5651 4061 79 24782 87 171 498 813 1976 1157 961 4 5667 82 317 1604 2856 5308 4012 2979 28 17186 171 489 2104 3676 7300 5178 3944 69 22931 7541 6409 17635 28137 46126 19909 12549 2080 140386 9231 7585 32001 56881 119894 72564 43048 5516 346720 80 37 153 304 523 235 97 2072 3501 16847 14020 49722 85189 166345 92547 55570 9668 489908 119 250 1337 2219 4055 2174 1083 6 174 92 938 2559 7002 3749 1630 14 420 342 2275 4779 11058 5923 2713 22 143 234 1145 2056 3875 2044 1154 4 167 115 960 2460 6984 3713 1752 14 430 349 2107 4517 10860 5760 2906 21 1527 6310 15167 20611 41242 15913 6665 21445 1931 4386 13109 27853 86109 36556 12623 33119 1773 17 142 224 302 100 38 3950 5227 10712 28403 48647 127558 52501 19284 58505 Total non-EU/EEA 11243 16158 27532 10655 16165 26950 128880 215686 6546 350837 Total WHO European Region 18843 40972 60019 17587 39147 56944 318377 669397 10055 996855 * Data from Bosnia and Herzegovina, Russia, Turkmenistan and Uzbekistan excluded due to inconsistent reporting during the period; data from Italy and Spain excluded due to increasing national coverage over the period. Therefore, totals by gender and overall may differ from totals presented in Tables 1-3. ** Annual totals include people diagnosed whose gender was unknown *** Cumulative total is the total number of cases reported by country since the start of reporting 48 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Female 2009 Male Total** Female 2010 Male Total** Female 2011 Male Total** Female 2012 Male Total** 145 272 770 1325 2485 1324 915 17 7253 118 282 1497 2538 5763 4591 2698 68 17555 263 554 2273 3885 8283 5930 3617 127 24932 158 224 708 1175 2300 1417 932 11 6925 118 289 1648 2499 5644 4416 2793 52 17459 276 513 2361 3689 7976 5851 3732 130 24528 125 206 689 1112 2300 1275 864 6 6577 110 279 1640 2793 5733 4469 2881 45 17950 238 485 2331 3906 8036 5750 3747 116 24609 116 197 591 1039 2268 1310 976 14 6511 100 327 1844 2902 5880 4574 3027 57 18711 218 524 2440 3951 8167 5891 4003 98 25292 73 388 1824 2307 3171 1264 452 7 114 90 1072 2870 6488 2827 833 19 356 478 2896 5179 9659 4092 1285 37 71 321 1561 2367 3368 1407 549 7 95 99 1112 2760 6715 3138 1007 13 343 420 2673 5127 10084 4545 1556 24 120 295 1586 2343 3802 1791 769 7 147 81 943 2537 6850 3262 1163 10 404 376 2530 4880 10653 5055 1933 21 169 284 1444 2250 3782 1869 858 9 241 76 798 2413 6788 3487 1449 13 559 360 2242 4663 10572 5356 2308 29 Age category EU/EEA <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown Total EU/EEA Non-EU/EEA <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown 9486 14313 23982 9651 14939 24772 10713 14993 25852 10665 15265 26089 Total non-EU/EEA 20203 39918 60428 46376 76754 123460 18867 38782 57877 18639 40419 59287 Total WHO European Region 49 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 9: New HIV diagnoses*, by sex, age and year of diagnosis (2005–2014) and cumulative totals Table 9b: West, Centre and East of the WHO European Region Age category West <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown Total West Centre <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown Total Centre Female 2005 Male Total** Female 2006 Male Total** Female 2007 Male Total** Female 2008 Male Total** 160 301 1124 2036 3398 1504 836 26 9385 161 225 1212 2500 6827 4484 2522 62 17993 323 527 2338 4549 10237 5995 3365 95 27429 160 243 923 1726 3340 1475 858 178 8903 143 202 1144 2393 6843 4896 2640 308 18569 303 446 2070 4126 10204 6378 3499 495 27521 176 260 851 1602 3210 1592 853 203 8747 135 234 1344 2686 7310 5179 2965 381 20234 311 495 2199 4299 10538 6788 3821 596 29047 145 261 767 1537 3205 1698 989 230 8832 143 285 1497 2791 7298 5745 3172 405 21336 288 548 2271 4334 10532 7452 4162 644 30231 35 98 109 136 156 69 45 17 29 99 160 293 453 250 161 37 64 197 270 433 612 322 207 73 28 94 88 136 145 68 38 6 36 80 185 290 506 231 125 38 64 174 275 434 659 304 163 70 25 76 93 120 157 51 57 5 18 86 204 348 511 252 183 38 45 163 304 486 690 311 245 80 21 64 117 128 182 65 64 3 21 74 221 369 636 340 187 27 42 139 346 508 838 411 251 82 665 1482 2178 603 1491 2143 584 1640 2324 644 1875 2617 1168 East <15 63 92 347 137 193 530 232 226 688 359 578 15–19 472 235 707 471 209 680 515 156 671 434 122 558 20–24 351 458 809 409 460 869 722 687 1409 2060 1211 3274 25–29 324 958 1282 427 994 1421 823 1371 2195 2649 3213 5871 30–39 1734 4398 6132 2170 5382 7552 2752 6196 8953 3137 6404 9565 40–49 573 1717 2290 749 2066 2815 919 2575 3495 1136 2722 3865 50+ 136 302 438 176 443 619 266 569 835 348 658 1009 Unknown 2694 3117 5811 3006 3346 6355 2033 2783 4819 14 9 27 Total East 6347 11277 17816 7545 13093 20841 8262 14563 23065 10137 14917 25337 16397 30752 47423 17051 33153 50505 17593 36437 54436 19613 38128 58185 Total WHO European Region Age category West <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown Total West Centre <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown Total Centre Female 2013 Male Total** Female 2014 Male Total** Female Cumulative total*** Male Unkown 86 182 574 1036 2449 1528 1166 9 7030 99 313 2037 3356 7212 5648 3973 30 22668 186 496 2613 4395 9671 7186 5142 41 29730 84 169 536 874 2213 1379 1124 7 6386 75 343 1852 3191 6418 5165 3835 25 20904 161 513 2391 4067 8642 6553 4963 35 27325 3451 4946 18074 30594 51617 22788 14315 2596 148381 3709 5735 32569 61084 135454 85195 51165 5494 380405 120 48 240 424 674 267 116 3496 5385 7271 10718 50820 91961 187508 108050 65441 11577 533346 26 28 124 153 259 132 94 4 31 67 453 755 1395 655 344 15 57 95 579 911 1657 788 438 55 29 38 99 170 309 133 125 - 31 90 512 868 1387 671 416 17 60 128 612 1044 1703 808 541 54 4704 1283 2573 2588 3490 1448 1003 291 6192 1472 5628 8017 13164 6198 3552 787 2 4 52 94 123 62 15 2208 10898 2758 8234 10666 16721 7679 4559 3286 903 3992 4950 17380 45010 2560 64801 Total 820 3715 4580 East <15 113 160 400 127 153 400 2259 3254 1731 7244 15–19 255 72 327 227 76 303 6958 5504 2 12464 20–24 1316 776 2092 1135 704 1839 14541 11419 3 25963 25–29 2191 2319 4510 2007 2133 4140 19456 24788 10 44254 30–39 3951 6498 10449 3719 6386 10105 39677 83410 30 123117 40–49 2123 3382 5505 2000 3371 5371 15440 34074 8 49522 50+ 1042 1379 2421 1082 1428 2510 5968 9641 4 15613 2 3 5 1 0 1 48317 71892 322 120531 Unknown Total East 10993 14589 25709 10298 14251 24669 152616 243982 2110 398708 Total WHO European Region 18843 40972 60019 17587 39147 56944 318377 669397 10055 996855 * Data from Bosnia and Herzegovina, Russia, Turkmenistan and Uzbekistan excluded due to inconsistent reporting during the period; data from Italy and Spain excluded due to increasing national coverage over the period. Therefore, totals by gender and overall may differ from totals presented in Tables 1-3. ** Annual totals include people diagnosed whose gender was unknown *** Cumulative total is the total number of cases reported by country since the start of reporting 50 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Female 2009 Male Total** Female 2010 Male Total** Female 2011 Male Total** Female 2012 Male Total** 146 234 686 1331 2979 1642 1071 310 8399 125 296 1545 2684 7316 5937 3475 567 21945 271 530 2234 4029 10312 7586 4547 881 30390 154 214 720 1383 2797 1771 1096 15 8150 117 313 1877 3006 7300 5857 3638 39 22147 271 527 2598 4395 10107 7637 4735 57 30327 129 207 700 1275 2719 1550 1071 7 7658 112 294 1849 3203 6998 5716 3644 30 21846 245 501 2550 4478 9721 7271 4718 39 29523 116 182 590 1180 2643 1608 1155 14 7488 95 328 2057 3408 7376 5922 3928 45 23159 213 510 2649 4595 10035 7534 5084 66 30686 29 47 131 125 184 61 66 2 23 57 256 400 765 366 238 30 52 104 390 535 967 436 307 73 24 26 130 112 181 79 63 4 21 41 321 444 754 359 250 23 45 67 455 565 958 448 319 94 22 28 145 128 207 115 65 3 25 59 357 560 985 472 287 20 47 87 504 689 1192 590 352 90 26 33 129 138 245 131 80 2 28 67 433 674 1169 593 308 20 54 100 565 815 1419 727 388 49 645 2135 2864 619 2213 2951 713 2765 3551 784 3292 4117 Total Centre 366 679 1214 482 663 1322 112 140 388 161 227 Age category West <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown Total West Centre <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown East 537 <15 427 102 529 347 114 461 299 70 369 284 61 345 15–19 2142 1131 3273 1821 1181 3002 1606 867 2473 1454 675 2129 20–24 2843 3087 5930 2750 2933 5683 2333 2465 4798 2204 2209 4413 25–29 3546 7028 10574 3708 7152 10860 3709 6614 10323 3665 6404 10069 30–39 1373 3014 4387 1525 3249 4774 1720 3027 4747 1785 3188 4973 40–49 459 780 1239 564 922 1486 713 980 1693 806 1198 2004 50+ 3 17 28 26410 36180 62594 4 8 12 8 6 11159 15838 27174 37607 52394 90182 10496 14171 24803 10367 13968 24484 Total East 14 Unknown 20203 39918 60428 46376 76754 123460 18867 38782 57877 18639 40419 59287 Total WHO European Region 51 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 10: HIV diagnoses in people infected through heterosexual contact, by country and transmission subcategory, cases diagnosed in 2014, in EU/EEA and other countries of the WHO European Region Area EU/EEA West West Centre Centre Centre Centre West East West West West West Centre West West West East Country* Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein East Lithuania West Luxembourg West Malta West Netherlands West Norway Centre Poland West Portugal Centre Romania Centre Slovakia Centre Slovenia West Spain West Sweden West United Kingdom Total EU/EEA Non-EU/EEA Centre Albania West Andorra East Armenia East Azerbaijan East Belarus Centre Bosnia and Herzegovina Yugoslav Republic of Centre former Macedonia, the East Georgia West Israel East Kazakhstan East Kyrgyzstan East Moldova West Monaco Centre Montenegro East Russia West San Marino Centre Serbia West Switzerland East Tajikistan Centre Turkey East Turkmenistan East Ukraine East Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region Case from country with generalised HIV epidemic Partner from a country with a generalised HIV epidemic N % Partner IDU N % 14 157 4 0 1 2 43 0 19 664 494 0 0 0 68 0 0 0 0 11 2 48 0 0 122 0 0 0 0 73 1048 2771 17.1 43.6 4.2 0.0 10.0 4.4 42.2 0.0 27.1 46.0 63.3 0.0 0.0 0.0 57.1 0.0 0.0 0.0 0.0 40.7 22.2 23.0 0.0 0.0 21.8 0.0 0.0 0.0 0.0 44.0 48.0 28.2 1 0 0 0 0 1 33 0 27 226 50 0 0 0 8 0 0 0 0 0 0 0 60 0 17 0 0 1 0 0 0 423 0 0 0 0 0 - 0.0 0.0 0.0 0.0 0.0 - 0 0 0 0 0 - 0 0.0 0 0.0 0 50 0 0 0 0 0 0 0 37 0 0 0 87 0.0 26.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.2 0.0 0.0 0.0 0.5 45 2 0 0 0 0 0 0 1 25 0 0 0 73 15.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 15.0 0.0 0.0 0.0 0.4 2850 8 0 2858 30.9 0.7 0.0 10.7 449 2 45 496 4.9 0.2 0.3 1.9 34 3 128 165 Other/ undetermined** Bisexual partner Total N % N % N % N 1.2 0.0 0.0 0.0 0.0 2.2 32.4 0.0 38.6 15.7 6.4 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.6 0.0 3.0 0.0 0.0 25.0 0.0 0.0 0.0 4.3 2 0 0 0 0 3 0 7 1 11 6 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 4 36 2.4 0.0 0.0 0.0 0.0 6.7 0.0 4.3 1.4 0.8 0.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.4 1 0 0 0 0 0 1 0 0 0 8 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 3 15 1.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.0 0.0 0.0 0.1 0.2 64 203 92 11 9 39 25 155 23 542 222 127 28 0 41 1598 132 0 66 16 7 161 81 88 420 320 18 2 875 93 1130 6588 78.0 56.4 95.8 100.0 90.0 86.7 24.5 95.7 32.9 37.6 28.5 100.0 100.0 0.0 34.5 100.0 100.0 0.0 100.0 59.3 77.8 77.0 57.4 100.0 75.0 100.0 100.0 50.0 100.0 56.0 51.7 67.0 82 360 96 11 10 45 102 162 70 1443 780 127 28 0 119 1598 132 0 66 27 9 209 141 88 560 320 18 4 875 166 2185 9833 0.0 0.0 0.0 0.0 0.0 - 0 0 19 43 0 - 0.0 0.0 7.3 12.0 0.0 - 0 0 0 0 0 - 0.0 0.0 0.0 0.0 0.0 - 61 0 243 316 1349 - 100.0 0.0 92.7 88.0 100.0 - 61 0 262 359 1349 - 0 0.0 0 0.0 4 100.0 4 45 7 0 14 0 0 0 0 0 1 0 0 0 129 15.4 3.6 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 202 133 1399 375 620 0 4 0 29 104 569 485 10648 16541 69.2 69.3 100.0 96.4 100.0 0.0 100.0 0.0 93.5 62.3 100.0 100.0 100.0 98.3 292 192 1399 389 620 0 4 0 31 167 569 485 10648 16831 0.4 0.2 0.8 0.6 14 2 0 16 0.2 0.2 0.0 0.1 5865 1190 16074 23129 63.7 98.8 98.9 86.7 9212 1205 16247 26664 * Country-specific comments are in Annex 5 ** The category ‘other/undetermined’ includes a substantial proportion of cases with partners reported as heterosexual from a non-generalised epidemic country in the following countries: Albania (18%), Armenia (93%), Azerbaijan (23%), Czech Republic (18%), Denmark (22%), Georgia (27%), Kyrgyzstan (48%), Moldova (99.7%), Norway (32%), Portugal (23%). Countries reporting aggregate data (Ukraine and Kazakhstan for 2014) are classified as unknown because information on region of origin and partner risk factors are not included in the aggregate reporting metadataset. 53 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 11: HIV diagnoses, by country of report and region of origin, cases diagnosed in 2014, in EU/EEA and other countries of the WHO European Region Area EU/EEA West West Centre Centre Centre Centre West East West West West West Centre West West West East Country* Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein East Lithuania West Luxembourg West Malta West Netherlands West Norway Centre Poland West Portugal Centre Romania Centre Slovakia Centre Slovenia West Spain West Sweden West United Kingdom Total EU/EEA Non-EU/EEA Centre Albania West Andorra East Armenia East Azerbaijan East Belarus Centre Bosnia and Herzegovina Centre former Yugoslav Republic of Macedonia, the East Georgia West Israel East Kazakhstan East Kyrgyzstan East Moldova West Monaco Centre Montenegro East Russia West San Marino Centre Serbia West Switzerland East Tajikistan Centre Turkey East Turkmenistan East Ukraine East Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region Country of report N % Western Europe N % Central & Eastern Europe N % Sub-Saharan Africa N % 124 353 231 89 36 173 129 285 81 1366 2111 506 0 2 130 2680 342 0 136 24 20 545 103 0 581 787 83 44 2287 69 2629 15946 52.8 34.0 93.5 96.7 64.3 74.6 50.4 97.9 44.8 31.6 59.9 70.9 0.0 18.2 36.2 72.5 98.6 0.0 96.5 34.8 50.0 65.6 38.4 0.0 63.2 99.5 96.5 89.8 67.9 19.7 42.8 53.2 11 93 1 0 11 7 23 0 8 66 108 5 0 3 22 40 1 1 1 18 8 28 23 0 8 0 0 0 106 12 514 1118 4.7 9.0 0.4 0.0 19.6 3.0 9.0 0.0 4.4 1.5 3.1 0.7 0.0 27.3 6.1 1.1 0.3 100.0 0.7 26.1 20.0 3.4 8.6 0.0 0.9 0.0 0.0 0.0 3.1 3.4 8.4 3.7 63 28 5 1 7 44 21 6 30 74 344 80 0 1 36 223 3 0 4 4 1 36 15 0 9 1 0 4 102 24 412 1578 26.8 2.7 2.0 1.1 12.5 19.0 8.2 2.1 16.6 1.7 9.8 11.2 0.0 9.1 10.0 6.0 0.9 0.0 2.8 5.8 2.5 4.3 5.6 0.0 1.0 0.1 0.0 8.2 3.0 6.9 6.7 5.3 20 214 7 0 1 3 51 0 15 940 487 24 0 3 78 387 0 0 0 19 5 81 64 0 169 0 3 0 185 143 1240 4139 8.5 20.6 2.8 0.0 1.8 1.3 19.9 0.0 8.3 21.7 13.8 3.4 0.0 27.3 21.7 10.5 0.0 0.0 0.0 27.5 12.5 9.7 23.9 0.0 18.4 0.0 3.5 0.0 5.5 40.9 20.2 13.8 76 0 332 586 1809 30 534 160 0 616 831 0 20 126 198 985 0 0 6303 98.7 0.0 100.0 97.0 99.9 100.0 99.6 33.5 0.0 95.5 100.0 0.0 100.0 100.0 38.4 100.0 0.0 0.0 23.4 0 3 0 0 0 0 0 8 0 0 0 0 0 0 77 0 0 0 88 0.0 100.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.3 0 0 0 18 2 0 2 131 0 25 0 0 0 0 21 0 0 0 199 0.0 0.0 0.0 3.0 0.1 0.0 0.4 27.5 0.0 3.9 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.7 0 0 0 0 0 0 0 67 0 0 0 0 0 0 64 0 0 0 131 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.5 14098 1695 6456 22249 51.6 34.2 26.2 39.1 1184 19 2 1206 4.3 0.4 0.0 2.1 1655 62 60 1777 6.1 1.3 0.2 3.1 4256 14 0 4270 15.6 0.3 0.0 7.5 * Country-specific comments are in Annex 5 ** Countries reporting aggregate data (Ukraine and Kazakhstan for 2014) are classified as unknown because information on region of origin is not included in the aggregate reporting metadataset. 54 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Latin America & Caribbean N Rate South & South-east Asia N % Other N % Unknown** N % Total Country 3 34 0 1 0 0 6 0 3 179 69 1 0 1 42 204 0 0 0 3 1 60 16 0 51 0 0 1 508 8 299 1490 1.3 3.3 0.0 1.1 0.0 0.0 2.3 0.0 1.7 4.1 2.0 0.1 0.0 9.1 11.7 5.5 0.0 0.0 0.0 4.3 2.5 7.2 6.0 0.0 5.5 0.0 0.0 2.0 15.1 2.3 4.9 5.0 7 14 0 0 1 5 16 0 12 52 96 17 0 0 13 51 0 0 0 0 1 31 31 0 1 0 0 0 0 39 276 663 3.0 1.3 0.0 0.0 1.8 2.2 6.3 0.0 6.6 1.2 2.7 2.4 0.0 0.0 3.6 1.4 0.0 0.0 0.0 0.0 2.5 3.7 11.6 0.0 0.1 0.0 0.0 0.0 0.0 11.1 4.5 2.2 1 21 3 0 0 0 9 0 0 103 50 13 0 1 3 97 1 0 0 0 4 25 5 0 0 0 0 0 68 20 167 591 0.4 2.0 1.2 0.0 0.0 0.0 3.5 0.0 0.0 2.4 1.4 1.8 0.0 9.1 0.8 2.6 0.3 0.0 0.0 0.0 10.0 3.0 1.9 0.0 0.0 0.0 0.0 0.0 2.0 5.7 2.7 2.0 6 282 0 1 0 0 1 0 32 1547 260 68 271 0 35 13 0 0 0 1 0 25 11 1061 101 3 0 0 110 35 604 4467 2.6 27.1 0.0 1.1 0.0 0.0 0.4 0.0 17.7 35.8 7.4 9.5 100.0 0.0 9.7 0.4 0.0 0.0 0.0 1.4 0.0 3.0 4.1 100.0 11.0 0.4 0.0 0.0 3.3 10.0 9.8 14.9 235 1039 247 92 56 232 256 291 181 4327 3525 714 271 11 359 3695 347 1 141 69 40 831 268 1061 920 791 86 49 3366 350 6141 29992 0 0 0 0 0 0 0 9 0 0 0 0 0 0 27 0 0 0 36 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.1 0 0 0 0 0 0 0 20 0 3 0 0 0 0 10 0 0 0 33 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.5 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 1 0 0 0 0 0 0 82 0 1 0 0 0 0 7 0 0 0 91 1.3 0.0 0.0 0.0 0.0 0.0 0.0 17.2 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.3 0 0 0 0 0 0 0 0 2350 0 0 0 0 0 111 0 1812 15796 20070 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 100.0 0.0 0.0 0.0 0.0 0.0 21.6 0.0 100.0 100.0 74.5 77 3 332 604 1811 30 536 477 2350 645 831 0 20 126 515 985 1812 15796 26953 1524 2 0 1526 5.6 0.0 0.0 2.7 687 6 3 696 2.5 0.1 0.0 1.2 676 4 2 682 2.5 0.1 0.0 1.2 3245 3148 18144 24537 11.9 63.6 73.6 43.1 27325 4950 24669 56945 EU/EEA Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein Lithuania Luxembourg Malta Netherlands Norway Poland Portugal Romania Slovakia Slovenia Spain Sweden United Kingdom Total EU/EEA Non-EU/EEA Albania Andorra Armenia Azerbaijan Belarus Bosnia and Herzegovina former Yugoslav Republic of Macedonia, the Georgia Israel Kazakhstan Kyrgyzstan Moldova Monaco Montenegro Russia San Marino Serbia Switzerland Tajikistan Turkey Turkmenistan Ukraine Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region 55 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 12: HIV diagnoses, by geographical area, transmission mode and country or subcontinent of origin, cases reported in 2014 Table 12a: EU/EEA and non-EU/EEA countries Transmission mode EU/EEA Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total EU/EEA Non-EU/EEA Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total non-EU/EEA Total WHO European Region Country of report N % Western Europe N % Central & Eastern Europe N % Sub-Saharan Africa N % 8921 888 4202 88 14 10 1823 15946 70.4 71.4 42.7 37.3 19.7 45.5 30.9 53.2 753 49 221 5 4 2 84 1118 5.9 3.9 2.2 2.1 5.6 9.1 1.4 3.7 578 170 562 13 7 1 246 1578 4.6 13.7 5.7 5.5 9.9 4.5 4.2 5.3 212 13 3426 97 36 3 352 4139 1.7 1.0 34.8 41.1 50.7 13.6 6.0 13.8 522 1258 3996 140 2 14 371 6303 22249 41.8 18.6 23.7 44.6 28.6 58.3 20.9 23.4 39.1 54 2 24 0 0 0 8 88 1206 4.3 0.0 0.1 0.0 0.0 0.0 0.5 0.3 2.1 23 39 108 1 1 1 26 199 1776 1.8 0.6 0.6 0.3 14.3 4.2 1.5 0.7 3.1 3 0 119 1 2 0 6 131 4270 0.2 0.0 0.7 0.3 28.6 0.0 0.3 0.5 7.5 Table 12b: West, Centre, East of the WHO European Region Transmission mode West Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total West Centre Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total Centre East Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total East Total WHO European Region 56 Country of report N % Western Europe N % Central & Eastern Europe N % Sub-Saharan Africa N % 8583 518 3469 59 14 8 1447 14098 71.5 60.5 37.7 28.0 18.7 42.1 29.3 51.6 794 50 240 5 4 2 89 1184 6.6 5.8 2.6 2.4 5.3 10.5 1.8 4.3 565 187 618 13 8 1 262 1655 4.7 21.8 6.7 6.2 10.7 5.3 5.3 6.1 215 13 3537 98 38 3 352 4256 1.8 1.5 38.4 46.4 50.7 15.8 7.1 15.6 652 214 570 24 0 2 233 1695 47.0 79.3 47.3 48.0 0.0 16.7 11.5 34.2 12 1 5 0 0 0 1 19 0.9 0.4 0.4 0.0 0.0 0.0 0.0 0.4 35 6 14 1 0 0 6 62 2.5 2.2 1.2 2.0 0.0 0.0 0.3 1.3 0 0 8 0 0 0 6 14 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.3 208 1414 4159 145 2 14 514 6456 22249 39.1 20.6 25.6 50.2 100.0 93.3 72.2 26.2 39.1 0 0 0 0 0 0 2 2 1206 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.1 1 16 38 0 0 1 4 60 1776 0.2 0.2 0.2 0.0 0.0 6.7 0.6 0.2 3.1 0 0 0 0 0 0 0 0 4270 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Latin America & Caribbean N % South & South-east Asia N % Other N % Unknown N % Total Transmission mode 903 10 455 5 2 0 115 1490 7.1 0.8 4.6 2.1 2.8 0.0 1.9 5.0 303 17 280 6 5 3 49 663 2.4 1.4 2.8 2.5 7.0 13.6 0.8 2.2 271 12 197 8 1 1 101 591 2.1 1.0 2.0 3.4 1.4 4.5 1.7 2.0 736 85 490 14 2 2 3138 4467 5.8 6.8 5.0 5.9 2.8 9.1 53.1 14.9 12677 1244 9833 236 71 22 5908 29992 24 2 9 0 0 0 1 36 1526 1.9 0.0 0.1 0.0 0.0 0.0 0.1 0.1 2.7 7 0 19 5 1 0 1 33 696 0.6 0.0 0.1 1.6 14.3 0.0 0.1 0.1 1.2 15 1 13 0 0 0 62 91 682 1.2 0.0 0.1 0.0 0.0 0.0 3.5 0.3 1.2 601 5452 12543 167 1 9 1299 20072 24539 48.1 80.7 74.5 53.2 14.3 37.5 73.2 74.5 43.1 1249 6754 16831 314 7 24 1774 26953 56944 Latin America & Caribbean N % South & South-east Asia N % Other N % Unknown N % EU/EEA Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total EU/EEA Non-EU/EEA Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total non-EU/EEA Total WHO European Region Total Transmission mode 925 12 464 5 2 0 116 1524 7.7 1.4 5.0 2.4 2.7 0.0 2.3 5.6 308 17 292 11 6 3 50 687 2.6 2.0 3.2 5.2 8.0 15.8 1.0 2.5 283 13 207 8 1 1 163 676 2.4 1.5 2.2 3.8 1.3 5.3 3.3 2.5 334 46 385 12 2 1 2465 3245 2.8 5.4 4.2 5.7 2.7 5.3 49.9 11.9 12007 856 9212 211 75 19 4944 27325 2 0 0 0 0 0 0 2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1 0 5 0 0 0 0 6 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 2 0 2 0 0 0 0 4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 682 49 601 25 1 10 1780 3148 49.2 18.1 49.9 50.0 100.0 83.3 87.9 63.6 1386 270 1205 50 1 12 2026 4950 0 0 0 0 0 0 0 0 1526 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 1 0 2 0 0 0 0 3 696 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1 0 1 0 0 0 0 2 682 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 321 5442 12047 144 0 0 192 18146 24539 60.3 79.2 74.1 49.8 0.0 0.0 27.0 73.6 43.1 532 6872 16247 289 2 15 712 24669 56944 West Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total West Centre Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total Centre East Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total East Total WHO European Region 57 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 13: New HIV diagnoses, by country of report and probable region of infection, in 2014, in EU/EEA and other countries of the WHO European Region Area EU/EEA West West Centre Centre Centre Centre West East West West West West Centre West West West East Country* Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein East Lithuania West Luxembourg West Malta West Netherlands West Norway Centre Poland West Portugal Centre Romania Centre Slovakia Centre Slovenia West Spain West Sweden West United Kingdom Total EU/EEA Non-EU/EEA Centre Albania West Andorra East Armenia East Azerbaijan East Belarus Centre Bosnia and Herzegovina Centre former Yugoslav Republic of Macedonia, the East Georgia West Israel East Kazakhstan East Kyrgyzstan East Moldova West Monaco Centre Montenegro East Russia West San Marino Centre Serbia West Switzerland East Tajikistan Centre Turkey East Turkmenistan East Ukraine East Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region Country of report N % Western Europe N % Central & Eastern Europe N % Sub-Saharan Africa N % 35 268 0 92 36 0 123 208 84 1252 0 714 271 1 143 0 213 0 97 21 33 516 75 958 587 787 76 0 0 67 3181 9838 14.9 25.8 0.0 100.0 64.3 0.0 48.0 71.5 46.4 28.9 0.0 100.0 100.0 9.1 39.8 0.0 61.4 0.0 68.8 30.4 82.5 62.1 28.0 90.3 63.8 99.5 88.4 0.0 0.0 19.1 51.8 32.8 2 40 0 0 6 2 23 5 13 0 0 0 0 0 19 0 4 0 5 0 4 20 36 0 5 0 3 0 0 26 300 513 0.9 3.8 0.0 0.0 0.0 0.9 9.0 1.7 7.2 0.0 0.0 0.0 0.0 0.0 5.3 0.0 1.2 0.0 3.5 0.0 10.0 2.4 13.4 0.0 0.5 0.0 3.5 0.0 0.0 7.4 4.9 1.7 2 14 0 0 5 1 15 1 36 0 0 0 0 0 11 0 3 0 4 0 0 7 16 0 2 1 4 0 0 22 201 345 0.9 1.3 0.0 0.0 8.9 0.4 5.9 0.3 19.9 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.9 0.0 2.8 0.0 0.0 0.8 6.0 0.0 0.2 0.1 4.7 0.0 0.0 6.3 3.3 1.2 5 115 0 0 1 0 48 0 15 0 0 0 0 1 57 0 0 0 0 0 0 29 66 0 93 0 3 0 0 132 836 1401 2.1 11.1 0.0 0.0 1.8 0.0 18.8 0.0 8.3 0.0 0.0 0.0 0.0 9.1 15.9 0.0 0.0 0.0 0.0 0.0 0.0 3.5 24.6 0.0 10.1 0.0 3.5 0.0 0.0 37.7 13.6 4.7 50 3 135 296 1809 30 230 268 0 613 678 0 0 0 0 198 0 0 0 4319 64.9 100.0 40.7 49.0 99.9 100.0 42.9 56.2 0.0 96.4 81.6 0.0 0.0 0.0 0.0 38.4 0.0 0.0 0.0 16.0 5 0 0 1 0 0 19 4 0 0 0 0 0 0 0 32 0 0 0 61 6.5 0.0 0.0 0.2 0.0 0.0 3.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.2 0 0 187 155 0 0 131 56 0 19 33 0 0 0 0 7 0 0 0 588 0.0 0.0 56.3 25.7 0.0 0.0 24.4 11.7 0.0 3.0 4.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 2.2 0 0 0 0 0 0 0 48 0 0 0 0 0 0 0 40 0 0 0 88 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.3 7569 2300 4288 14157 27.7 46.5 17.4 24.9 524 16 34 574 1.9 0.3 0.1 1.0 389 11 533 933 1.4 0.2 2.2 1.6 1485 4 0 1489 5.4 0.1 0.0 2.6 * Country-specific comments are in Annex 5 ** Countries reporting aggregate data (Ukraine and Kazakhstan for 2014) are classified as unknown because information on probable country of infection is not included in the aggregate reporting metadataset. 58 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Latin America & Caribbean N Rate South & South-east Asia N % Other N % Unknown** N % Total Country 1 15 0 0 1 1 4 0 1 0 0 0 0 0 25 0 0 0 0 0 1 12 10 0 13 0 0 0 0 7 95 186 0.4 1.4 0.0 0.0 1.8 0.4 1.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 2.5 1.4 3.7 0.0 1.4 0.0 0.0 0.0 0.0 2.0 1.5 0.6 2 26 0 0 0 2 28 2 29 0 0 0 0 0 4 0 0 0 0 1 0 19 48 0 0 0 0 0 0 53 264 478 0.9 2.5 0.0 0.0 0.0 0.9 10.9 0.7 16.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.4 0.0 2.3 17.9 0.0 0.0 0.0 0.0 0.0 0.0 15.1 4.3 1.6 0 8 0 0 2 0 8 0 3 0 0 0 0 1 9 0 0 0 0 0 2 4 7 0 0 0 0 0 0 30 99 173 0.0 0.8 0.0 0.0 3.6 0.0 3.1 0.0 1.7 0.0 0.0 0.0 0.0 9.1 2.5 0.0 0.0 0.0 0.0 0.0 5.0 0.5 2.6 0.0 0.0 0.0 0.0 0.0 0.0 8.6 1.6 0.6 188 553 247 0 5 226 7 75 0 3075 3525 0 0 8 91 3695 127 1 35 47 0 224 10 103 220 3 0 49 3366 13 1165 17058 80.0 53.2 100.0 0.0 8.9 97.4 2.7 25.8 0.0 71.1 100.0 0.0 0.0 72.7 25.3 100.0 36.6 100.0 24.8 68.1 0.0 27.0 3.7 9.7 23.9 0.4 0.0 100.0 100.0 3.7 19.0 56.9 235 1039 247 92 56 232 256 291 181 4327 3525 714 271 11 359 3695 347 1 141 69 40 831 268 1061 920 791 86 49 3366 350 6141 29992 0 0 0 0 0 0 0 5 0 0 0 0 0 0 0 14 0 0 0 19 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0 0 0 0 0 0 1 14 0 3 0 0 0 0 0 16 0 0 0 34 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.1 0 0 3 0 0 0 1 13 0 1 0 0 0 0 0 6 0 0 0 24 0.0 0.0 0.9 0.0 0.0 0.0 0.2 2.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 22 0 7 152 2 0 154 69 2350 0 120 0 20 3 126 202 985 1812 15796 21820 28.6 0.0 2.1 25.2 0.1 0.0 28.7 14.5 100.0 0.0 14.4 0.0 100.0 100.0 100.0 39.2 100.0 100.0 100.0 81.0 77 3 332 604 1811 30 536 477 2350 636 831 0 20 3 126 515 985 1812 15796 26953 203 2 0 205 0.7 0.0 0.0 0.4 504 2 6 512 1.8 0.0 0.0 0.9 190 2 5 197 0.7 0.0 0.0 0.3 16461 2613 19803 38878 60.2 52.8 80.3 68.3 27325 4950 24669 56945 EU/EEA Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein Lithuania Luxembourg Malta Netherlands Norway Poland Portugal Romania Slovakia Slovenia Spain Sweden United Kingdom Total EU/EEA Non-EU/EEA Albania Andorra Armenia Azerbaijan Belarus Bosnia and Herzegovina former Yugoslav Republic of Macedonia, the Georgia Israel Kazakhstan Kyrgyzstan Moldova Monaco Montenegro Russia San Marino Serbia Switzerland Tajikistan Turkey Turkmenistan Ukraine Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region 59 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 14: Percentage of new HIV diagnoses (2014) among persons >14 years reported with information about CD4 cell count, by CD4 cell count level (<200 and <350 cells per mm3 blood) and by transmission mode in cases with CD4 <350, in EU/EEA and other countries of the WHO European Region Area EU/EEA West West Centre Centre Centre Centre West East West West West West Centre West West West East Country* Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein East Lithuania West Luxembourg West Malta West Netherlands West Norway Centre Poland West Portugal Centre Romania Centre Slovakia Centre Slovenia West Spain West Sweden West United Kingdom Total EU/EEA Non-EU/EEA Centre Albania West Andorra East Armenia East Azerbaijan East Belarus Centre Bosnia and Herzegovina Former Yugoslav Republic of Centre Macedonia, the East Georgia West Israel East Kazakhstan East Kyrgyzstan East Moldova West Monaco Centre Montenegro East Russia West San Marino Centre Serbia West Switzerland East Tajikistan Centre Turkey*** East Turkmenistan East Ukraine East Uzbekistan total Non EU-EEA WHO European Region West Centre East Total WHO European Region Number of cases with CD4** Completeness (%) CD4 CD4 <200 (%) CD4 <350 (%) CD4 < 350 per mm3 blood (%) N % N % Hetero IDU MSM 222 605 220 48 203 174 162 140 2308 516 306 2862 247 1 56 760 686 731 62 45 2888 5169 18411 94.9 59.0 89.8 85.7 87.9 69.0 56.8 79.1 53.7 72.3 86.0 77.8 72.0 100.0 83.6 92.3 75.1 94.8 72.1 91.8 85.9 84.6 61.4 61 137 60 7 30 42 62 36 620 159 81 998 82 1 12 193 227 280 12 22 801 1131 5069 27.5 22.6 27.3 14.6 14.8 24.1 38.3 25.7 26.9 30.8 26.5 34.9 33.2 100.0 21.4 25.4 33.1 38.3 19.4 48.9 27.7 21.9 27.4 109 261 95 13 64 79 102 58 1080 264 145 1529 130 1 29 337 351 426 23 28 1334 2080 8608 49.1 43.1 43.2 27.1 31.5 45.4 63.0 41.4 46.8 51.2 47.4 53.4 52.6 100.0 51.8 44.3 51.2 58.3 37.1 62.2 46.2 40.2 46.6 59.5 52.9 53.8 50.0 38.5 57.1 60.4 49.2 55.6 66.1 60.9 49.7 53.9 56.5 58.8 54.8 53.2 68.8 57.0 54.9 55.4 30.0 25.0 44.7 100.0 37.5 50.0 69.6 20.0 59.5 77.3 42.9 46.1 52.3 41.7 63.0 61.6 50.0 75.0 64.2 60.9 45.8 31.4 35.4 16.2 28.6 37.9 66.7 30.0 32.7 37.0 37.0 35.6 45.8 100.0 57.9 36.6 42.5 48.3 24.4 63.3 39.5 28.9 36.9 52 295 347 - 74.3 90.8 59.2 - 32 108 108 - 61.5 36.6 31.1 - 40 162 179 - 76.9 54.9 51.6 - 74.4 51.9 47.7 - 100.0 77.1 62.5 - 87.5 50.0 42.9 - 24 80.0 1 4.2 9 37.5 33.3 - 38.1 468 248 149 463 16 107 338 622 88 3217 88.3 54.6 24.9 57.0 80.0 85.6 66.1 71.7 4.9 12.3 162 74 45 121 5 45 96 227 11 1035 34.6 29.8 30.2 26.1 31.3 42.1 28.4 36.5 12.5 32.2 273 121 106 243 7 72 162 399 35 1808 58.3 48.8 71.1 52.5 43.8 67.3 47.9 64.1 39.8 56.2 56.9 58.9 67.5 52.4 66.7 77.8 56.7 62.4 40.5 56.5 69.4 48.1 84.6 51.7 100.0 80.0 71.2 68.3 37.9 40.2 75.0 66.7 41.7 56.9 38.8 40.0 42.1 43.3 17278 1596 2753 21627 63.0 33.0 11.5 37.9 4668 505 915 6088 27.0 31.6 33.2 28.1 7939 812 1594 10345 46.2 50.9 57.9 48.0 55.7 54.1 56.1 55.7 61.7 58.5 67.7 63.7 37.0 39.1 44.4 37.2 * Country-specific comments are in Annex 5 ** Completeness is for all cases; there is some variation by country for CD4 cell count completeness by transmission group *** Data for Turkey exclude people diagnosed with AIDS at the time of HIV diagnosis. 61 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 15: AIDS diagnoses and rates per 100 000 population, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region Area EU/EEA West West Centre Centre Centre Centre West East West West West West Centre West West West East Country* Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein East Lithuania West Luxembourg West Malta West Netherlands West Norway Centre Poland West Portugal Centre Romania Centre Slovakia Centre Slovenia West Spain West Sweden West United Kingdom Total EU/EEA Non-EU/EEA Centre Albania West Andorra East Armenia East Azerbaijan East Belarus Centre Bosnia and Herzegovina Yugoslav Republic of Centre former Macedonia, the East Georgia West Israel East Kazakhstan East Kyrgyzstan East Moldova West Monaco Centre Montenegro East Russia*** West San Marino Centre Serbia**** West Switzerland East Tajikistan Centre Turkey East Turkmenistan East Ukraine East Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region Year of start of reporting 2005 2006 2007 2008 2009 N Rate N Rate N Rate N Rate N Rate 1982 1983 1987 1986 1986 1986 1980 1992 1983 1980 1981 1981 1986 1985 1983 1982 1990 1989 1988 1983 1986 1999 1983 1986 1985 1985 1985 1986 1981 1982 1981 96 156 19 21 11 13 44 29 26 1371 736 104 33 1 42 1531 119 0 10 11 3 357 32 151 995 379 3 10 1874 46 980 9203 1.2 1.5 0.2 0.5 1.5 0.1 0.8 2.1 0.5 2.2 0.9 0.9 0.3 0.3 1 7.9 5.3 0 0.3 2.4 0.7 2.2 0.7 0.4 9.5 1.8 0.1 0.5 4.3 0.5 1.6 2 98 106 16 20 8 18 51 32 26 1184 720 90 22 3 42 1454 90 0 27 9 7 285 32 167 920 324 4 5 1752 55 891 8458 1.2 1 0.2 0.5 1.1 0.2 0.9 2.4 0.5 1.9 0.9 0.8 0.2 1 1 6 4 0 0.8 1.9 1.7 1.7 0.7 0.4 8.8 1.5 0.1 0.2 4 0.6 1.5 1.8 110 105 21 11 12 23 32 57 33 1019 664 93 23 0 35 1405 81 0 28 11 2 298 9 141 813 311 6 9 1639 62 844 7897 1.3 1 0.3 0.3 1.6 0.2 0.6 4.2 0.6 1.6 0.8 0.8 0.2 0 0.8 4.5 3.7 0 0.9 2.3 0.5 1.8 0.2 0.4 7.7 1.5 0.1 0.4 3.7 0.7 1.4 1.7 97 119 29 25 12 29 40 61 27 1063 587 109 23 2 36 1341 103 0 54 8 9 278 18 180 847 336 1 11 1544 829 7818 1.2 1.1 0.4 0.6 1.5 0.3 0.7 4.6 0.5 1.7 0.7 1 0.2 0.6 0.8 3.6 4.7 0 1.7 1.7 2.2 1.7 0.4 0.5 8 1.6 0 0.5 3.4 1.3 1.6 90 121 30 22 8 23 36 38 23 954 624 103 23 0 35 1204 101 0 37 3 1 271 18 131 692 268 4 18 1418 655 6952 1.1 1.1 0.4 0.5 1 0.2 0.7 2.8 0.4 1.5 0.8 0.9 0.2 0 0.8 2.1 4.7 0 1.2 0.6 0.2 1.6 0.4 0.3 6.6 1.3 0.1 0.9 3.1 1.1 1.4 1993 2004 1988 1995 1991 1986 12 0 41 20 163 6 0.4 0 1.4 0.2 1.7 0.2 10 0 46 21 331 4 0.3 0 1.5 0.2 3.4 0.1 24 1 59 200 308 4 0.8 1.2 2 2.3 3.2 0.1 32 2 83 76 351 5 1.1 2.4 2.8 0.9 3.7 0.1 34 0 84 109 532 2 1.2 0 2.8 1.2 5.6 0.1 1989 10 0.5 10 0.5 10 0.5 9 0.4 2 0.1 1989 1981 1993 1999 1989 1985 1990 140 61 100 23 60 1 5 1 52 196 4 32 0 4217 11 5155 3.1 0.9 0.6 0.4 1.4 3 0.8 3.4 0.6 2.6 0.1 0 0 9 0 2.2 162 70 132 29 93 0 5 1 51 160 21 30 0 4723 13 5912 3.7 1 0.8 0.6 2.2 0 0.8 3.3 0.6 2.1 0.3 0 0 10.2 0 2.5 183 49 176 24 218 0 3 0 39 176 30 30 0 4573 35 6142 4.2 0.7 1.1 0.5 5.3 0 0.5 0 0.4 2.3 0.4 0 0 9.9 0.1 2.6 232 53 174 36 92 0 6 0 39 161 55 55 0 4380 184 6025 5.3 0.7 1.1 0.7 2.2 0 1 0 0.4 2.1 0.8 0.1 0 9.5 0.7 2.6 284 52 173 75 262 0 8 0 52 151 70 67 0 4437 129 6523 6.6 0.7 1.1 1.4 6.4 0 1.3 0 0.6 2 0.9 0.1 0 9.7 0.5 2.8 8664 757 4937 14358 2.4 0.4 3.6 2.1 7956 694 5720 14370 2.1 0.4 4.2 2.1 7400 667 5972 14039 1.9 0.4 4.3 2 7170 792 5881 13843 1.9 0.4 4.3 2 6452 692 6331 13475 1.6 0.4 4.6 1.8 1986 1985 1980 1998 1985 2002 1988 1992 * Country-specific comments are in Annex 5 ** Cumulative total is the total number of cases reported by the country since the start of reporting *** Includes data from Kosovo (without prejudice to positions on status, and in line with UNSCR 1244 and the ICJ Opinion on the Kosovo Declaration of Independence): 2005 (4), 2006 (0, 0.0), 2007 (1, 0.0), 2008 (1, 0.0), 2009 (0, 0.0), 2010 (3, 0.1), 2011 (3, 0.2), 2012 (1, 0.1), 2013 (1, 0.1), 2014 (1, 0.1), cumulative 1986-2014 (50). 62 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT 2010 2011 2012 2013 2014 Cumulative Country* total** N Rate N Rate N Rate N Rate N Rate 81 104 32 21 10 26 44 26 32 978 508 103 28 1 38 1145 132 0 33 8 6 286 22 173 736 248 2 7 1206 667 6704 1 1 0.4 0.5 1.2 0.2 0.8 2 0.6 1.5 0.6 0.9 0.3 0.3 0.8 1.9 6.2 0 1.1 1.6 1.4 1.7 0.5 0.5 7 1.2 0 0.3 2.6 1.1 1.3 78 87 40 26 5 26 59 38 25 847 495 101 32 2 47 1052 112 1 21 11 5 229 19 184 632 323 4 15 1063 421 6000 0.9 0.8 0.5 0.6 0.6 0.2 1.1 2.9 0.5 1.3 0.6 0.9 0.3 0.6 1 1.8 5.4 2.8 0.7 2.1 1.2 1.4 0.4 0.5 6 1.6 0.1 0.7 2.3 0.7 1.2 91 92 65 28 7 30 41 36 19 817 488 122 48 1 36 1066 142 1 38 8 6 256 25 157 581 325 7 11 953 432 5929 1.1 0.8 0.9 0.7 0.8 0.3 0.7 2.7 0.4 1.3 0.6 1.1 0.5 0.3 0.8 1.8 6.9 2.7 1.3 1.5 1.4 1.5 0.5 0.4 5.5 1.6 0.1 0.5 2 0.7 1.2 68 80 71 17 3 27 38 26 20 659 412 137 42 1 27 1056 133 0 44 10 1 220 28 161 459 345 6 11 683 345 5132 0.8 0.7 1 0.4 0.3 0.3 0.7 2 0.4 1 0.5 1.2 0.4 0.3 0.6 1.8 6.6 0 1.5 1.9 0.2 1.3 0.6 0.4 4.4 1.7 0.1 0.5 1.8 0.5 1 76 84 64 22 6 24 29 18 20 405 235 115 51 0 29 858 171 1 37 9 4 157 45 125 249 378 4 16 444 344 4020 0.9 0.7 0.9 0.5 0.7 0.2 0.5 1.4 0.4 0.6 0.3 1.1 0.5 0 0.6 1.4 8.5 2.7 1.3 1.6 0.9 0.9 0.9 0.3 2.4 1.9 0.1 0.8 1.3 0.5 0.8 2949 4469 529 440 254 428 2956 434 636 69786 30474 3678 796 67 1220 67248 1524 12 415 289 107 5964 1114 3172 20857 8774 78 228 84538 2172 28657 344265 26 0 94 210 475 6 0.9 0 3.2 2.3 5 0.2 46 1 87 195 590 7 1.6 1.3 2.9 2.1 6.2 0.2 49 0 133 235 598 4 1.7 0 4.5 2.5 6.3 0.1 65 2 144 189 547 7 2.3 2.6 4.8 2 5.8 0.2 50 0 171 200 474 - 1.7 0 5.7 2.1 5 - 406 8 1006 1519 4544 127 6 0.3 8 0.4 10 0.5 10 0.5 16 0.8 149 339 38 264 130 306 0 7 0 0 49 163 101 60 0 5861 220 8355 8 0.5 1.6 2.4 7.5 0 1.1 0 0 0.5 2.1 1.3 0.1 0 12.8 0.8 3.5 395 55 226 90 439 0 2 1 53 127 136 80 0 9189 11727 9.4 0.7 1.4 1.6 10.8 0 0.3 3.1 0.6 1.6 1.8 0.1 0 20.2 5.5 359 46 234 88 183 0 7 2 54 94 150 95 0 10073 12414 8.7 0.6 1.4 1.6 4.5 0 1.1 6 0.6 1.2 1.9 0.1 0 22.2 5.8 303 43 261 67 234 0 7 0 45 95 170 95 9362 11646 7.4 0.6 1.5 1.2 5.7 0 1.1 0 0.5 1.2 2.1 0.1 20.7 5.4 268 63 236 81 234 1 7 44 47 156 125 9844 12017 6.6 0.8 1.4 1.4 5.7 3 1.1 0.5 0.6 1.9 0.2 23 5.6 2932 1534 2209 678 2285 50 95 0 23 1784 9686 899 1237 1 75579 651 107402 6167 701 8191 15059 1.5 0.4 5.9 2 5357 851 11518 17727 1.3 0.4 10.3 2.5 5176 897 12269 18343 1.3 0.5 10.9 2.6 4386 912 11480 16778 1.1 0.5 10.2 2.3 3214 932 11890 16037 0.8 0.5 10.7 2.3 338482 18497 94676 451667 EU/EEA Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein Lithuania Luxembourg Malta Netherlands Norway Poland Portugal Romania Slovakia Slovenia Spain Sweden United Kingdom Total EU/EEA Non-EU/EEA Albania Andorra Armenia Azerbaijan Belarus Bosnia and Herzegovina former Yugoslav Republic of Macedonia, the Georgia Israel Kazakhstan Kyrgyzstan Moldova Monaco Montenegro Russia San Marino Serbia*** Switzerland Tajikistan Turkey Turkmenistan Ukraine Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region 63 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 16: AIDS diagnoses in males and rates per 100 000 population, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region Area EU/EEA West West Centre Centre Centre Centre West East West West West West Centre West West West East Country* Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein East Lithuania West Luxembourg West Malta West Netherlands West Norway Centre Poland West Portugal Centre Romania Centre Slovakia Centre Slovenia West Spain West Sweden West United Kingdom Total EU/EEA Non-EU/EEA Centre Albania West Andorra East Armenia East Azerbaijan East Belarus Centre Bosnia and Herzegovina Yugoslav Republic of Centre former Macedonia, the East Georgia West Israel East Kazakhstan East Kyrgyzstan East Moldova West Monaco Centre Montenegro East Russia West San Marino Centre Serbia*** West Switzerland East Tajikistan Centre Turkey East Turkmenistan East Ukraine East Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region 2005 N Rate 2006 N Rate 2007 N Rate 2008 N Rate 2009 N Rate Rate 67 83 16 19 6 8 30 15 25 924 600 80 29 1 28 1145 74 0 7 6 1 272 18 117 790 208 2 8 1448 35 622 6684 1.7 1.6 0.4 0.9 1.7 0.2 1.1 2.4 1 3 1.5 1.5 0.6 0.7 1.4 12.1 7.2 0 0.4 2.6 0.5 3.4 0.8 0.6 15.6 2 0.1 0.8 6.8 0.8 2.1 3 75 66 12 14 7 13 31 22 20 817 595 65 15 2 34 1080 63 0 22 6 5 224 24 130 677 187 4 5 1355 33 532 6135 1.9 1.3 0.3 0.7 1.9 0.3 1.2 3.5 0.8 2.7 1.5 1.2 0.3 1.3 1.6 9.2 6.2 0 1.4 2.6 2.5 2.8 1 0.7 13.4 1.8 0.2 0.5 6.2 0.7 1.8 2.7 86 65 18 10 8 18 22 46 22 697 528 71 17 0 18 1077 59 0 26 8 2 228 6 109 615 180 4 7 1280 40 558 5825 2.1 1.3 0.5 0.5 2.2 0.4 0.8 7.4 0.9 2.3 1.3 1.3 0.4 0 0.8 7.2 5.8 0 1.7 3.4 1 2.8 0.3 0.6 12.1 1.7 0.2 0.7 5.8 0.9 1.9 2.5 78 76 20 24 10 22 33 44 24 720 488 96 21 2 27 991 77 0 45 5 9 225 11 139 627 181 0 9 1173 517 5694 1.9 1.5 0.5 1.2 2.6 0.4 1.2 7.1 0.9 2.3 1.2 1.7 0.4 1.2 1.2 5.5 7.6 0 3 2.1 4.4 2.8 0.5 0.8 12.4 1.8 0 0.9 5.2 1.7 2.5 63 76 22 20 8 17 25 26 15 677 506 81 17 0 27 908 67 0 28 2 1 228 13 99 503 158 3 16 1086 447 5139 1.6 1.4 0.6 1 2.1 0.3 0.9 4.2 0.6 2.2 1.3 1.5 0.4 0 1.2 3.2 6.7 0 1.9 0.8 0.5 2.8 0.5 0.5 9.9 1.6 0.1 1.6 4.7 1.5 2.1 62 59 21 20 7 20 34 21 23 671 420 84 26 1 27 845 86 0 27 4 4 225 20 132 518 141 2 7 933 437 4878 1.5 1.1 0.6 1 1.8 0.4 1.2 3.4 0.9 2.1 1 1.5 0.5 0.6 1.2 3 8.9 0 1.9 1.6 1.9 2.7 0.8 0.7 10.2 1.4 0.1 0.7 4.1 1.4 2 11 0 32 16 114 4 0.7 0 2.2 0.4 2.5 0.2 6 0 37 19 220 3 0.4 0 2.5 0.4 4.9 0.2 20 1 46 169 208 4 1.3 2.4 3 3.9 4.7 0.2 23 2 62 68 231 4 1.5 4.6 4.1 1.6 5.2 0.2 32 0 57 90 326 2 2.2 0 3.7 2 7.4 0.1 18 0 73 195 291 6 1.2 0 4.8 4.3 6.6 0.3 8 0.8 9 0.9 9 0.9 5 0.5 2 0.2 6 0.6 105 44 78 20 49 1 5 1 44 142 4 27 0 2986 10 3701 5 1.4 1.1 0.8 2.5 6.2 1.7 6.9 1 3.9 0.1 0.1 0 13.8 0.1 3.3 129 52 88 23 53 0 4 1 39 113 16 26 0 3407 9 4254 6.2 1.6 1.2 0.9 2.7 0 1.3 6.8 0.9 3.1 0.5 0.1 0 15.8 0.1 3.8 138 38 111 24 137 0 3 0 25 126 21 25 0 3208 27 4340 6.7 1.1 1.5 0.9 6.9 0 1 0 0.6 3.4 0.6 0.1 0 15 0.2 3.8 179 34 124 24 59 0 4 0 29 113 43 48 0 3060 141 4253 8.7 1 1.6 0.9 3 0 1.3 0 0.7 3 1.2 0.1 0 14.4 1.1 3.7 209 34 111 61 166 0 6 0 45 108 55 60 0 3019 92 4475 10.3 0.9 1.4 2.3 8.4 0 2 0 1 2.8 1.5 0.2 0 14.3 0.7 3.9 245 22 194 111 179 0 7 0 0 42 121 79 46 0 3988 163 5786 12.1 0.6 2.5 4.1 9.1 0 2.3 0 0 0.9 3.1 2.1 0.1 0 18.9 1.2 5 6363 512 3510 10385 3.5 0.6 5.4 3.1 5807 474 4108 10389 3.2 0.5 6.3 3.1 5488 457 4220 10165 2.9 0.5 6.4 2.9 5251 539 4157 9947 2.8 0.6 6.3 2.9 4800 507 4307 9614 2.4 0.6 6.5 2.7 4511 501 5652 10664 2.2 0.5 8.5 2.9 * Country-specific comments are in Annex 5 ** Cumulative total is the total number of cases reported by the country since the start of reporting *** Includes data from Kosovo (without prejudice to positions on status, and in line with UNSCR 1244 and the ICJ Opinion on the Kosovo Declaration of Independence): 2005 (3), 2006 (0), 2007 (1), 2008 (1), 2009 (0), 2010 (2), 2011 (2), 2012 (1), 2013 (0), 2014 (1), cumulative 1986-2014 (33). 64 2010 N HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT 2011 N Rate 2012 N Rate 2013 N Rate 2014 N Rate Cumulative Country* total** 60 55 38 25 2 18 40 31 18 620 416 85 27 1 34 800 80 1 15 7 3 181 17 142 461 199 4 12 828 288 4508 1.5 1 1.1 1.2 0.5 0.3 1.5 5 0.7 2 1 1.6 0.6 0.6 1.5 2.8 8.4 5.6 1.1 2.7 1.5 2.2 0.7 0.8 9.1 2 0.2 1.2 3.6 0.9 1.8 72 56 47 26 6 24 35 25 16 562 384 101 45 1 28 778 102 1 28 5 5 201 23 120 414 204 7 10 731 298 4355 1.8 1 1.3 1.3 1.4 0.5 1.3 4 0.6 1.8 1 1.9 1 0.6 1.2 2.7 10.9 5.5 2 1.9 2.4 2.4 0.9 0.7 8.2 2.1 0.3 1 3.2 1 1.8 50 57 53 14 2 22 29 19 17 473 329 118 38 1 20 796 90 0 31 9 1 179 19 130 323 235 6 10 532 250 3854 1.2 1 1.5 0.7 0.5 0.4 1 3.1 0.6 1.5 0.8 2.2 0.8 0.6 0.9 2.8 9.7 0 2.3 3.4 0.5 2.2 0.7 0.7 6.5 2.4 0.2 1 2.8 0.8 1.6 54 53 52 20 5 18 23 13 14 274 200 93 41 0 20 651 110 1 29 6 4 131 36 100 198 271 3 15 352 235 3022 1.3 1 1.5 1 1.2 0.3 0.8 2.1 0.5 0.9 0.5 1.8 0.9 0 0.9 2.2 12 5.4 2.1 2.2 1.9 1.6 1.4 0.5 4 2.8 0.1 1.5 2.2 0.7 1.3 2245 3038 400 387 198 348 2511 320 518 54951 26078 3096 696 58 937 51847 1060 11 335 225 93 4801 871 2498 16559 5098 66 200 67362 1775 22444 271026 35 1 65 171 365 4 2.4 2.5 4.3 3.7 8.3 0.2 34 0 95 209 375 4 2.4 0 6.4 4.5 8.5 0.2 50 1 100 162 369 6 3.5 2.6 6.9 3.4 8.4 0.3 36 0 124 162 310 - 2.5 0 8.7 3.4 7 - 312 6 746 1320 2932 102 5 0.5 8 0.8 9 0.9 13 1.3 110 277 37 150 69 269 0 2 1 45 89 84 65 0 6141 7875 13.9 1 1.9 2.5 13.7 0 0.7 6.4 1 2.3 2.2 0.2 0 29.2 7.6 248 34 180 65 93 0 7 2 50 66 106 83 0 6498 8157 12.6 0.9 2.2 2.3 4.7 0 2.3 12.3 1.1 1.7 2.6 0.2 0 31 7.8 219 32 192 49 128 0 7 0 39 67 95 76 6013 7614 11.3 0.8 2.3 1.7 6.5 0 2.3 0 0.9 1.7 2.3 0.2 28.8 7.3 201 44 176 56 141 1 4 38 36 104 99 6119 7664 10.5 1.1 2.1 1.9 7.2 6.2 1.3 0.9 0.9 2.5 0.3 30.9 7.4 2179 1113 1585 533 1393 39 77 0 21 1348 7210 612 1028 0 50886 494 74046 4042 623 7717 12383 2 0.7 14.5 3.6 3812 675 8024 12512 1.9 0.7 15.1 3.6 3304 697 7467 11468 1.6 0.7 14 3.3 2425 715 7545 10686 1.2 0.8 14.3 3.1 267798 12868 64395 345072 EU/EEA Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein Lithuania Luxembourg Malta Netherlands Norway Poland Portugal Romania Slovakia Slovenia Spain Sweden United Kingdom Total EU/EEA Non-EU/EEA Albania Andorra Armenia Azerbaijan Belarus Bosnia and Herzegovina former Yugoslav Republic of Macedonia, the Georgia Israel Kazakhstan Kyrgyzstan Moldova Monaco Montenegro Russia San Marino Serbia*** Switzerland Tajikistan Turkey Turkmenistan Ukraine Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region 65 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 17: AIDS diagnoses in females and rates per 100 000 population, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region Area EU/EEA West West Centre Centre Centre Centre West East West West West West Centre West West West East Country* Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein East Lithuania West Luxembourg West Malta West Netherlands West Norway Centre Poland West Portugal Centre Romania Centre Slovakia Centre Slovenia West Spain West Sweden West United Kingdom Total EU/EEA Non-EU/EEA Centre Albania West Andorra East Armenia East Azerbaijan East Belarus Centre Bosnia and Herzegovina Yugoslav Republic of Centre former Macedonia, the East Georgia West Israel East Kazakhstan East Kyrgyzstan East Moldova West Monaco Centre Montenegro East Russia West San Marino Centre Serbia*** West Switzerland East Tajikistan Centre Turkey East Turkmenistan East Ukraine East Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region 2005 N Rate 2006 N Rate 2007 N Rate 2008 N Rate 2009 N Rate Rate 29 73 3 2 5 5 14 14 1 446 136 24 4 0 14 386 45 0 3 5 2 85 14 34 205 171 1 2 426 11 358 2518 0.7 1.4 0.1 0.1 1.3 0.1 0.5 1.9 0 1.4 0.3 0.4 0.1 0 0.7 3.8 3.7 0 0.2 2.1 1 1 0.6 0.2 3.8 1.6 0 0.2 1.9 0.2 1.2 1.1 22 40 4 6 1 5 20 10 6 365 125 25 7 1 8 374 27 0 5 3 2 61 8 37 243 137 0 0 397 22 359 2320 0.5 0.7 0.1 0.3 0.3 0.1 0.7 1.4 0.2 1.1 0.3 0.4 0.1 0.7 0.4 3 2.2 0 0.3 1.3 1 0.7 0.3 0.2 4.5 1.3 0 0 1.8 0.5 1.2 1 24 40 3 1 4 5 10 11 11 317 136 22 6 0 15 328 22 0 2 3 0 70 3 32 198 131 2 2 359 22 286 2065 0.6 0.7 0.1 0 1 0.1 0.4 1.5 0.4 1 0.3 0.4 0.1 0 0.7 2.1 1.8 0 0.1 1.2 0 0.8 0.1 0.2 3.6 1.2 0.1 0.2 1.6 0.5 0.9 0.8 19 43 9 1 2 7 7 17 3 340 99 13 2 0 9 350 26 0 9 3 0 53 7 41 220 155 1 2 371 312 2121 0.4 0.8 0.2 0 0.5 0.1 0.3 2.4 0.1 1 0.2 0.2 0 0 0.4 1.8 2.2 0 0.5 1.2 0 0.6 0.3 0.2 4 1.5 0 0.2 1.6 1 0.9 27 45 8 2 0 6 11 12 8 275 118 22 6 0 8 296 34 0 9 1 0 43 5 32 189 110 1 2 332 208 1811 0.6 0.8 0.2 0.1 0 0.1 0.4 1.7 0.3 0.8 0.3 0.4 0.1 0 0.4 1 2.9 0 0.5 0.4 0 0.5 0.2 0.2 3.4 1 0 0.2 1.4 0.7 0.7 19 45 11 1 3 6 10 5 9 305 88 19 2 0 11 300 46 0 6 4 2 61 2 41 218 107 0 0 273 230 1824 0.4 0.8 0.3 0 0.7 0.1 0.4 0.7 0.3 0.9 0.2 0.3 0 0 0.5 1 4 0 0.4 1.6 1 0.7 0.1 0.2 4 1 0 0 1.2 0.7 0.7 1 0 9 4 49 2 0.1 0 0.6 0.1 1 0.1 4 0 9 2 111 1 0.3 0 0.6 0 2.2 0.1 4 0 13 31 100 0 0.3 0 0.9 0.7 2 0 9 0 21 8 120 1 0.6 0 1.4 0.2 2.4 0.1 2 0 27 19 206 0 0.1 0 1.9 0.4 4.1 0 8 0 21 15 184 0 0.6 0 1.5 0.3 3.6 0 2 0.2 1 0.1 1 0.1 4 0.4 0 0 0 0 35 17 21 3 11 0 0 0 8 54 0 5 0 1231 1 1453 1.5 0.5 0.3 0.1 0.5 0 0 0 0.2 1.4 0 0 0 4.9 0 1.3 33 18 44 6 40 0 1 0 12 47 5 4 0 1316 4 1658 1.4 0.5 0.5 0.2 1.9 0 0.3 0 0.3 1.2 0.1 0 0 5.3 0 1.4 45 11 65 0 81 0 0 0 14 50 9 5 0 1365 8 1802 1.9 0.3 0.8 0 3.8 0 0 0 0.3 1.3 0.3 0 0 5.5 0.1 1.6 53 19 50 9 33 0 2 0 10 48 12 7 0 1320 43 1769 2.3 0.5 0.6 0.3 1.5 0 0.6 0 0.2 1.2 0.3 0 0 5.3 0.3 1.5 75 18 62 14 96 0 2 0 7 42 15 7 0 1418 37 2047 3.3 0.5 0.7 0.5 4.5 0 0.6 0 0.2 1.1 0.4 0 0 5.8 0.3 1.7 94 16 70 19 127 0 0 0 0 7 42 22 14 0 1873 57 2569 4.2 0.4 0.8 0.7 6 0 0 0 0 0.2 1.1 0.6 0 0 7.6 0.4 2.1 2300 245 1426 3971 1.2 0.3 2.1 1.1 2146 220 1612 3978 1.1 0.2 2.3 1.1 1905 210 1752 3867 1 0.2 2.5 1.1 1916 253 1721 3890 1 0.3 2.4 1.1 1649 185 2024 3858 0.8 0.2 2.8 1 1654 200 2539 4393 0.8 0.2 3.5 1.2 * Country-specific comments are in Annex 5 ** Cumulative total is the total number of cases reported by the country since the start of reporting *** Includes data from Kosovo (without prejudice to positions on status, and in line with UNSCR 1244 and the ICJ Opinion on the Kosovo Declaration of Independence): 2005 (1), 2006 (0), 2007 (0), 2008 (0), 2009 (0), 2010 (1), 2011 (1), 2012 (0), 2013 (1), 2014 (0), cumulative 1986-2014 (17). 66 2010 N HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT 2011 N Rate 2012 N Rate 2013 N Rate 2014 N Rate Cumulative Country* total** 18 32 2 1 3 8 19 7 7 226 79 16 5 1 13 252 32 0 6 4 2 48 2 42 171 124 0 3 235 133 1491 0.4 0.6 0.1 0 0.7 0.1 0.7 1 0.3 0.7 0.2 0.3 0.1 0.6 0.6 0.8 2.8 0 0.4 1.6 1 0.6 0.1 0.2 3.1 1.2 0 0.3 1 0.4 0.6 19 36 18 2 1 6 6 11 3 252 104 21 3 0 8 288 40 0 10 3 1 55 2 37 167 121 0 1 222 134 1571 0.4 0.6 0.5 0.1 0.2 0.1 0.2 1.6 0.1 0.7 0.2 0.4 0.1 0 0.3 0.9 3.6 0 0.6 1.1 0.5 0.7 0.1 0.2 3 1.2 0 0.1 0.9 0.4 0.6 18 23 18 3 1 5 9 7 3 181 83 19 4 0 7 260 43 0 13 1 0 41 9 31 136 110 0 1 151 95 1273 0.4 0.4 0.5 0.1 0.2 0.1 0.3 1 0.1 0.5 0.2 0.3 0.1 0 0.3 0.8 3.9 0 0.8 0.4 0 0.5 0.4 0.2 2.5 1.1 0 0.1 0.8 0.3 0.5 22 31 12 2 1 6 6 5 6 131 35 21 10 0 9 207 61 0 8 3 0 26 9 25 51 107 1 1 92 109 997 0.5 0.5 0.3 0.1 0.2 0.1 0.2 0.7 0.2 0.4 0.1 0.4 0.2 0 0.4 0.7 5.6 0 0.5 1.1 0 0.3 0.4 0.1 0.9 1 0 0.1 0.5 0.3 0.4 702 1429 129 53 56 80 445 114 118 14808 4396 581 100 9 281 15401 464 1 80 64 14 1163 243 674 4297 3676 12 28 17176 397 6213 73204 11 0 22 24 225 3 0.8 0 1.5 0.5 4.4 0.2 15 0 38 26 223 0 1 0 2.5 0.6 4.4 0 15 1 44 27 178 1 1 2.7 2.8 0.6 3.5 0.1 14 0 47 38 164 - 1 0 3 0.8 3.2 - 94 2 260 199 1612 23 0 0 2 0.2 1 0.1 3 0.3 33 118 18 76 21 170 0 0 0 8 38 52 15 0 3048 3849 5.4 0.5 0.9 0.7 8 0 0 0 0.2 0.9 1.4 0 0 12.5 3.6 111 12 54 23 90 0 0 0 4 28 44 12 0 3575 4257 5.1 0.3 0.6 0.8 4.3 0 0 0 0.1 0.7 1.1 0 0 14.7 3.9 84 11 69 18 106 0 0 0 6 28 75 19 3349 4032 3.9 0.3 0.8 0.6 5 0 0 0 0.1 0.7 1.9 0 13.8 3.6 67 19 60 25 93 0 3 6 11 52 26 3725 4353 3.2 0.5 0.7 0.8 4.4 0 0.9 0.1 0.3 1.3 0.1 16.2 4 753 421 620 142 892 11 18 0 2 436 2475 287 209 1 24693 157 33340 1314 225 3801 5340 0.6 0.2 6.5 1.5 1361 222 4245 5828 0.6 0.2 7.2 1.6 1077 215 4013 5305 0.5 0.2 6.8 1.4 788 217 4345 5350 0.4 0.2 7.5 1.5 70648 5621 30274 106544 EU/EEA Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein Lithuania Luxembourg Malta Netherlands Norway Poland Portugal Romania Slovakia Slovenia Spain Sweden United Kingdom Total EU/EEA Non-EU/EEA Albania Andorra Armenia Azerbaijan Belarus Bosnia and Herzegovina former Yugoslav Republic of Macedonia, the Georgia Israel Kazakhstan Kyrgyzstan Moldova Monaco Montenegro Russia San Marino Serbia Switzerland Tajikistan Turkey Turkmenistan Ukraine Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region 67 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 18: AIDS diagnoses in men infected through sex with men, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region Area EU/EEA West West Centre Centre Centre Centre West East West West West West Centre West West West East Country* Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein East Lithuania West Luxembourg West Malta West Netherlands West Norway Centre Poland West Portugal Centre Romania Centre Slovakia Centre Slovenia West Spain West Sweden West United Kingdom Total EU/EEA Non-EU/EEA Centre Albania West Andorra East Armenia East Azerbaijan East Belarus Centre Bosnia and Herzegovina Yugoslav Republic of Centre former Macedonia, the East Georgia West Israel East Kazakhstan East Kyrgyzstan East Moldova West Monaco Centre Montenegro East Russia West San Marino Centre Serbia*** West Switzerland East Tajikistan Centre Turkey East Turkmenistan East Ukraine East Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region Year of diagnosis 2009 2010 2011 2012 2013 2014 Cumulative total** 31 31 5 19 4 10 15 0 7 249 252 63 23 0 13 252 10 0 0 2 0 127 9 29 83 14 1 7 338 201 1796 31 30 2 18 0 12 13 0 6 236 213 54 24 0 17 265 7 0 2 5 1 111 9 42 88 13 3 7 314 146 1669 25 23 8 22 1 11 13 1 2 189 211 50 37 0 14 261 4 0 2 3 0 123 10 25 81 7 3 8 308 156 1598 22 21 12 11 2 12 11 0 4 193 188 48 30 0 6 298 10 0 5 7 1 115 15 45 55 15 2 7 225 113 1473 24 26 9 15 4 8 10 1 6 100 112 37 37 0 10 237 7 1 3 3 1 76 18 32 42 23 2 10 155 121 1130 999 1418 76 235 107 202 1734 27 292 27943 17890 1994 551 43 378 11578 107 2 71 126 42 2933 504 607 2633 166 43 130 12804 1086 14921 101642 1 0 1 4 2 5 5 1 2 1 6 2 6 0 2 1 3 4 6 1 5 3 3 3 8 0 7 1 4 - 48 4 22 15 21 28 2005 2006 2007 2008 22 40 7 3 2 6 18 1 10 336 341 50 19 0 6 314 4 0 0 2 1 154 11 23 84 5 1 5 291 8 250 2014 34 25 4 11 2 3 17 1 8 292 340 38 10 2 8 309 3 0 1 2 3 124 11 14 79 10 3 4 302 9 245 1914 37 25 4 6 4 8 13 0 13 247 317 44 12 0 7 316 3 0 2 2 0 134 2 19 81 3 2 6 300 17 254 1878 27 22 4 12 4 7 16 1 10 257 274 57 16 1 8 300 3 0 7 0 1 132 6 27 108 9 0 7 322 229 1867 31 34 4 17 4 10 12 0 6 263 279 49 13 0 10 293 7 0 1 1 0 135 7 25 73 14 1 10 315 189 1803 0 0 1 0 0 1 0 0 0 0 0 0 2 1 1 2 0 0 6 1 3 1 0 0 6 0 0 1 0 0 3 2 2 2 1 1 4 3 3 5 37 5 12 0 0 0 1 1 1 15 49 0 4 0 8 0 101 3 9 0 0 0 0 3 0 18 43 0 4 0 8 0 90 3 5 0 1 2 0 2 0 12 63 0 5 0 9 0 110 7 5 1 0 0 0 3 0 15 48 0 11 0 10 0 113 3 8 0 0 2 0 4 0 25 42 0 2 0 10 0 104 10 6 0 0 2 0 5 0 0 22 61 0 3 0 10 0 133 11 8 1 0 2 0 1 1 21 34 0 0 0 31 131 11 4 0 0 0 0 4 2 30 33 0 0 0 45 148 16 8 1 0 0 0 3 0 19 31 0 12 50 164 21 9 0 0 2 1 3 22 18 0 15 55 171 104 308 3 1 12 22 38 0 11 381 3269 0 108 0 239 1 4672 2001 95 19 2115 1900 88 16 2004 1878 87 23 1988 1824 123 33 1980 1747 136 24 1907 1741 149 39 1929 1583 154 63 1800 1508 169 69 1746 1362 182 93 1637 1006 193 101 1301 102932 2757 623 106314 * Country-specific comments are in Annex 5 ** Cumulative total is the total number of cases reported by the country since the start of reporting *** Includes data from Kosovo (in accordance with the UN Security Council Resolution No. 1244 (1999)): 2005 (0), 2006 (0), 2007 (0), 2008 (1), 2009 (0), 2010 (0), 2011 (0), 2012 (0), 2013 (0), 2014 (1), cumulative 1986-2014 (3). 68 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 19: AIDS diagnoses in people infected through injecting drug use, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region Area EU/EEA West West Centre Centre Centre Centre West East West West West West Centre West West West East Country* Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein East Lithuania West Luxembourg West Malta West Netherlands West Norway Centre Poland West Portugal Centre Romania Centre Slovakia Centre Slovenia West Spain West Sweden West United Kingdom Total EU/EEA Non-EU/EEA Centre Albania West Andorra East Armenia East Azerbaijan East Belarus Centre Bosnia and Herzegovina Yugoslav Republic of Centre former Macedonia, the East Georgia West Israel East Kazakhstan East Kyrgyzstan East Moldova West Monaco Centre Montenegro East Russia West San Marino Centre Serbia*** West Switzerland East Tajikistan Centre Turkey East Turkmenistan East Ukraine East Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region Year of diagnosis 2009 2010 2005 2006 2007 2008 18 9 1 1 0 0 4 16 7 129 62 5 2 0 9 446 71 0 7 3 0 26 4 76 442 2 0 0 850 4 33 2227 19 7 0 1 0 4 3 23 1 106 82 5 0 0 9 398 51 0 17 0 2 10 4 89 356 3 0 0 750 3 25 1968 20 3 1 1 0 3 3 45 8 87 63 3 1 0 10 383 45 0 21 2 0 13 0 77 278 3 0 0 671 6 30 1777 24 8 4 0 0 5 6 41 1 85 52 3 0 0 11 318 60 0 35 0 0 7 2 74 263 2 0 0 537 27 1565 15 5 7 0 0 2 3 26 2 56 46 6 0 0 8 275 49 0 20 0 0 10 1 55 217 4 0 0 450 19 1276 0 0 27 12 97 1 0 0 28 13 216 1 1 0 25 131 198 1 0 1 30 50 191 0 0 0 33 69 265 0 2011 2012 2013 2014 Cumulative total** 11 3 10 1 0 4 4 14 3 60 34 3 0 0 6 228 70 0 20 0 0 6 3 70 212 12 0 0 336 27 1137 12 4 17 1 0 1 4 20 0 58 40 8 0 0 10 194 57 0 9 1 0 8 0 61 159 27 0 0 290 14 996 18 1 39 1 0 2 4 15 4 43 40 22 0 0 3 180 70 0 21 0 0 4 1 55 145 57 0 0 226 11 962 12 2 29 0 0 2 5 9 2 33 30 41 0 0 1 179 62 0 19 0 0 4 1 43 96 77 0 0 156 10 813 14 1 26 0 0 2 1 6 0 18 9 42 0 0 0 105 73 0 16 1 1 1 0 25 42 101 0 1 91 12 588 771 274 135 25 3 33 254 241 55 13797 4302 240 6 5 374 34755 835 7 195 40 4 335 155 1469 9126 294 1 7 49776 242 1504 119260 0 0 41 160 208 0 1 0 33 148 266 0 0 0 42 159 242 0 0 0 24 123 193 0 1 0 34 109 155 - 3 2 360 1019 2128 18 1 2 1 0 0 0 0 0 0 0 9 79 4 0 17 42 0 0 0 11 41 2 1 0 3041 3 3379 105 14 102 19 45 0 0 0 7 29 12 1 0 3360 9 3963 103 9 96 20 101 0 0 0 12 21 14 2 0 3086 20 3841 134 12 118 27 55 0 0 0 6 19 35 1 0 2868 116 3663 170 7 104 53 103 0 0 0 11 14 50 4 0 2732 70 3685 186 3 185 102 95 0 0 0 0 6 11 59 2 0 3458 131 4647 191 7 132 58 101 0 0 0 12 17 71 2 0 4979 6018 160 9 151 55 17 0 1 0 5 6 74 1 0 4933 5855 141 15 157 38 22 0 0 0 8 7 51 1 4273 5053 117 11 144 38 28 0 0 5 2 60 2 3856 4562 1574 236 1190 455 723 19 4 0 6 655 3299 433 61 0 38604 380 51178 2096 96 3414 5606 1823 108 4000 5931 1610 103 3905 5618 1376 92 3760 5228 1134 83 3744 4961 950 105 4729 5784 826 122 6065 7014 717 161 5939 6817 594 160 5112 5866 351 163 4636 5150 119571 2723 48137 170438 * Country-specific comments are in Annex 5 ** Cumulative total is the total number of cases reported by the country since the start of reporting *** No AIDS diagnoses in people infected through injecting drug use reported from Kosovo (without prejudice to positions on status, and in line with UNSCR 1244 and the ICJ Opinion on the Kosovo Declaration of Independence). 69 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 20: AIDS diagnoses in people infected through heterosexual contact, by country and year of diagnosis (2005-2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region Area EU/EEA West West Centre Centre Centre Centre West East West West West West Centre West West West East Country* Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein East Lithuania West Luxembourg West Malta West Netherlands West Norway Centre Poland West Portugal Centre Romania Centre Slovakia Centre Slovenia West Spain West Sweden West United Kingdom Total EU/EEA Non-EU/EEA Centre Albania West Andorra East Armenia East Azerbaijan East Belarus Centre Bosnia and Herzegovina Yugoslav Republic of Centre former Macedonia, the East Georgia West Israel East Kazakhstan East Kyrgyzstan East Moldova West Monaco Centre Montenegro East Russia West San Marino Centre Serbia*** West Switzerland East Tajikistan Centre Turkey East Turkmenistan East Ukraine East Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region Year of diagnosis 2009 2010 2005 2006 2007 2008 48 95 11 14 7 7 22 10 8 724 199 45 8 1 25 660 31 0 3 5 2 140 16 36 447 127 2 2 579 23 642 3939 39 64 12 8 6 9 29 8 15 610 193 41 11 1 22 626 21 0 3 7 2 108 16 35 470 106 1 0 535 36 562 3596 45 66 16 4 6 11 16 10 11 546 180 36 5 0 14 614 22 0 4 7 2 111 7 27 441 112 3 2 490 30 505 3343 39 75 15 10 7 14 16 17 11 592 146 45 5 0 13 604 25 0 6 8 5 102 10 34 455 116 1 1 535 512 3419 38 73 19 4 4 11 18 10 12 508 154 36 8 0 15 525 32 0 15 1 1 104 10 24 385 108 1 0 491 386 2994 12 0 9 8 51 4 10 0 17 6 103 3 20 0 32 55 99 3 26 0 46 14 145 5 28 0 45 34 254 2 2011 2012 2013 2014 Cumulative total** 31 66 14 1 5 12 23 7 12 528 118 31 4 1 12 558 36 0 11 6 6 121 10 51 423 106 1 0 394 376 2964 30 49 20 6 5 12 40 9 15 440 151 33 7 2 17 500 34 0 9 5 3 83 9 43 379 158 1 3 344 244 2651 37 65 15 4 4 13 22 16 10 487 132 38 6 1 19 507 55 1 13 4 5 98 12 34 341 138 3 1 316 248 2645 27 44 20 6 1 10 21 10 12 351 116 28 10 0 17 491 37 0 15 2 0 72 11 34 294 139 4 3 223 203 2202 35 49 25 4 1 12 17 8 9 231 72 27 12 0 15 423 59 17 5 2 56 27 28 158 143 2 0 148 186 1771 885 2336 282 150 124 158 782 125 222 19780 3988 952 152 15 342 16513 405 3 118 105 37 1995 397 611 8352 2070 29 41 15279 667 10038 86953 24 0 42 38 246 1 39 0 50 44 305 4 40 0 83 68 348 0 55 1 102 57 344 3 40 0 120 83 301 - 342 2 565 424 2246 68 6 6 4 4 1 3 3 6 6 10 84 41 41 0 5 15 0 3 0 13 97 2 16 0 941 0 1264 53 41 19 8 43 0 2 0 17 85 9 15 0 1089 2 1528 61 33 33 0 108 0 1 0 8 84 14 20 0 1265 6 1846 76 34 38 6 31 0 3 0 12 73 17 32 0 1342 51 1955 102 34 55 17 101 0 4 0 9 75 18 28 0 1509 40 2356 132 26 70 24 146 0 2 0 0 11 83 39 26 0 2264 68 3245 181 38 81 26 321 0 1 0 11 68 53 36 0 3944 5205 184 30 76 27 118 0 2 0 9 49 57 35 0 4873 6005 139 19 87 24 139 0 1 0 7 50 81 41 4875 6031 126 42 87 37 173 0 3 10 19 75 58 5806 6990 1150 841 546 180 1233 6 43 0 5 400 2624 366 592 0 28536 183 40436 3819 268 1116 5203 3502 241 1381 5124 3238 242 1709 5189 3275 285 1814 5374 2867 251 2232 5350 2825 261 3123 6209 2450 349 5057 7856 2421 310 5918 8650 1983 340 5910 8233 1521 348 6892 8761 86163 5146 36077 127389 * Country-specific comments are in Annex 5 ** Cumulative total is the total number of cases reported by the country since the start of reporting *** Includes data from Kosovo (without prejudice to positions on status, and in line with UNSCR 1244 and the ICJ Opinion on the Kosovo Declaration of Independence): 2005 (4), 2006 (0), 2007 (1), 2008 (0), 2009 (0), 2010 (3), 2011 (3), 2012 (1), 2013 (1), 2014 (0), cumulative 1986-2014 (46). 70 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 21: AIDS diagnoses in people infected through mother-to-child transmission, by country and year of diagnosis (2005–2014) and cumulative totals, in EU/EEA and other countries of the WHO European Region Area EU/EEA West West Centre Centre Centre Centre West East West West West West Centre West West West East Country* Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein East Lithuania West Luxembourg West Malta West Netherlands West Norway Centre Poland West Portugal Centre Romania Centre Slovakia Centre Slovenia West Spain West Sweden West United Kingdom Total EU/EEA Non-EU/EEA Centre Albania West Andorra East Armenia East Azerbaijan East Belarus Centre Bosnia and Herzegovina Yugoslav Republic of Centre former Macedonia, the East Georgia West Israel East Kazakhstan East Kyrgyzstan East Moldova West Monaco Centre Montenegro East Russia West San Marino Centre Serbia*** West Switzerland East Tajikistan Centre Turkey East Turkmenistan East Ukraine East Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region Year of diagnosis 2009 2010 2011 2012 2013 2014 Cumulative total** 0 0 2 0 0 0 1 0 0 5 1 1 0 0 1 3 0 0 0 0 0 5 0 1 1 8 0 0 3 11 43 1 0 1 1 0 0 0 0 0 8 2 0 0 0 0 3 2 0 0 0 0 2 0 3 1 11 0 0 3 7 45 0 0 0 0 0 0 0 0 0 11 2 0 1 0 0 4 1 0 0 1 0 1 0 1 1 11 0 0 3 1 38 0 0 3 0 0 0 1 0 0 9 1 0 0 0 1 7 2 0 1 0 0 2 1 0 3 16 0 0 3 4 54 0 2 0 0 0 0 0 0 1 1 0 0 0 0 0 2 0 0 0 0 0 2 0 0 1 8 0 0 0 2 19 13 123 7 4 2 0 25 2 7 777 115 24 4 0 36 738 18 0 1 4 1 64 7 58 119 297 0 2 974 22 705 4149 0 0 1 1 13 0 1 0 1 1 12 0 2 0 0 3 4 0 4 0 4 3 3 0 0 0 7 2 8 - 9 0 20 14 105 0 1 0 1 1 0 6 11 1 2 0 3 0 0 0 0 1 2 1 0 0 129 8 174 8 1 5 3 3 0 0 0 0 0 5 0 0 118 158 1 1 2 4 1 0 0 0 0 1 6 1 0 88 115 3 1 6 1 9 0 0 0 1 1 14 0 59 110 2 0 1 0 3 0 0 0 0 2 1 60 86 63 39 31 11 44 0 1 0 0 26 109 29 13 0 1078 22 1620 28 17 158 203 26 17 110 153 34 25 105 164 11 9 85 105 3902 429 1438 5769 2005 2006 2007 2008 1 0 0 0 1 0 0 0 0 10 3 0 1 0 0 4 1 0 0 0 0 1 0 3 5 8 0 0 9 1 32 80 0 1 0 0 0 0 2 0 0 6 1 1 0 0 0 9 2 0 0 0 0 3 0 4 3 7 0 0 7 1 27 74 1 4 0 0 0 0 0 0 1 8 2 0 0 0 1 2 0 0 0 0 0 4 0 1 3 6 0 0 10 2 27 72 1 4 0 0 0 0 0 0 0 9 0 0 0 0 3 2 5 0 0 0 0 2 0 5 4 7 0 0 8 22 72 2 1 0 0 0 0 0 0 0 10 0 0 1 0 1 5 1 0 0 0 0 3 0 7 3 13 0 0 8 20 75 0 0 2 0 13 0 0 0 1 0 10 0 1 0 1 2 7 0 0 0 0 0 12 0 0 0 2 2 10 0 0 0 1 0 0 6 2 0 0 1 0 0 0 1 0 0 1 0 139 0 165 1 2 1 1 4 0 0 0 1 0 0 0 0 122 2 145 13 1 5 0 7 0 0 0 1 1 1 0 0 110 3 154 10 1 4 2 6 0 0 0 2 0 0 0 0 73 6 116 4 1 5 0 1 0 0 0 1 1 0 2 0 86 3 118 68 15 162 245 63 12 144 219 67 10 149 226 56 14 118 188 55 24 114 193 35 13 169 217 * Country-specific comments are in Annex 5 ** Cumulative total is the total number of cases reported by country since the start of reporting *** No AIDS diagnoses in people infected through mother-to-child transmission reported from Kosovo (without prejudice to positions on status, and in line with UNSCR 1244 and the ICJ Opinion on the Kosovo Declaration of Independence) 71 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 22: AIDS diagnoses*, by sex, transmission mode and year of diagnosis (2005–2014) and cumulative totals Table22a: EU/EEA and non-EU/EEA countries Transmission mode EU/EEA Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total EU/EEA Non-EU/EEA Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total non-EU/EEA Total WHO European Region Transmission mode EU/EEA Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total EU/EEA Non-EU/EEA Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total non-EU/EEA Total WHO European Region * Female 2005 Male Total** Female 2006 Male Total** Female 2007 Male Total** Female 2008 Male Total** 428 1756 41 32 27 223 2507 2005 1795 2160 38 48 25 578 6649 2006 2223 3916 79 80 52 801 9157 391 1607 35 28 23 214 2298 1902 1574 1953 38 35 19 581 6102 1905 1965 3560 73 63 42 795 8403 360 1412 30 14 24 203 2043 1855 1411 1900 40 23 16 540 5785 1861 1771 3313 70 37 40 743 7835 336 1484 32 25 26 218 2121 1864 1229 1935 40 27 29 570 5694 1867 1565 3419 72 52 55 788 7818 43 130 12 2 1 31 219 2726 91 291 189 14 6 0 109 700 7349 91 334 319 26 8 1 141 920 10077 107 211 7 1 1 10 337 2635 82 486 223 14 2 0 27 834 6936 82 593 434 21 3 1 37 1171 9574 120 263 19 1 12 14 429 2472 101 614 309 22 2 14 39 1101 6886 101 734 572 41 3 26 53 1530 9365 94 263 17 0 2 29 405 2526 103 582 294 20 1 1 47 1048 6742 103 679 557 37 1 3 76 1456 9274 Female 2013 Male Total** Female 2014 Male Total** Female Cumulative total*** Male Unkown Total 175 919 27 5 7 139 1272 1468 638 1282 27 8 7 423 3853 1473 813 2201 54 13 14 562 5130 98 732 12 6 6 143 997 1130 490 1038 7 5 10 342 3022 1130 588 1771 19 11 16 485 4020 0 24549 37509 2057 2371 1354 5028 72868 100571 94511 48877 2072 5936 1705 15740 269412 28 2 4 0 0 0 1 35 100556 119018 86286 4127 8307 3058 20741 342093 91 506 21 1 3 60 682 1954 111 689 647 30 2 1 115 1595 5448 111 780 1153 51 3 4 175 2277 7407 95 482 9 2 2 38 628 1625 116 611 702 17 1 2 96 1545 4566 116 706 1184 26 3 4 134 2173 6192 0 2316 5305 239 107 26 469 8462 81329 4392 9843 6333 280 288 31 1369 22536 291937 2 4 2 1 0 0 5 14 49 4393 12163 11631 520 395 57 1841 31000 373081 Data from Bosnia and Herzegovina, Russia, San Marino, Sweden, Turkmenistan, Ukraine and Uzbekistan excluded due to inconsistent reporting during the period. Therefore, totals by gender and overall may differ from totals presented in Tables 15-21. ** Annual totals include people diagnosed whose gender was unknown *** Cumulative total is the total number of cases reported by country since the start of reporting 72 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Female 2009 Male Total** Female 2010 Male Total** Female 2011 Male Total** Female 2012 Male Total** 255 1278 39 16 13 209 1810 1802 1021 1715 36 21 15 529 5139 1803 1276 2993 75 37 28 739 6951 241 1347 30 6 13 187 1824 1793 896 1617 13 17 13 528 4877 1795 1137 2964 43 23 26 715 6703 179 1114 23 7 11 157 1491 1668 817 1537 22 3 10 451 4508 1669 996 2651 45 10 21 608 6000 195 1170 21 10 16 159 1571 1595 767 1475 17 15 4 482 4355 1598 962 2645 38 25 20 641 5929 125 411 15 6 2 33 592 2402 94 757 394 14 3 3 97 1362 6501 94 883 805 29 9 5 130 1955 8906 130 440 17 3 1 48 639 2463 118 928 472 20 1 4 86 1629 6506 118 1058 912 37 4 5 134 2268 8971 142 618 14 0 1 23 798 2289 95 897 638 26 9 2 62 1729 6236 97 1039 1257 40 9 3 85 2530 8529 94 535 13 1 1 38 682 2253 97 828 597 14 9 1 107 1653 6007 97 922 1132 27 10 2 145 2335 8263 Transmission mode EU/EEA Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total EU/EEA Non-EU/EEA Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total non-EU/EEA Total WHO European Region 73 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 22: AIDS diagnoses*, by sex, transmission mode and year of diagnosis (2005–2014) and cumulative totals Table 22b: West, Centre, East of the WHO European Region Transmission mode West Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total West Centre Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total Centre East Men who have sex with men Female 2005 Male Total** Female 2006 Male Total** Female 2007 Male Total** Female 2008 Male Total** 389 1700 36 17 2 145 2289 1991 1703 2096 31 33 1 472 6327 1992 2092 3796 67 50 3 617 8617 366 1573 28 13 3 141 2124 1888 1454 1893 34 21 4 479 5773 1891 1820 3466 62 34 7 620 7900 329 1385 29 10 2 128 1883 1855 1275 1822 36 14 3 443 5448 1861 1604 3208 65 24 5 571 7338 299 1434 25 15 3 140 1916 1821 1077 1841 31 20 4 457 5251 1824 1376 3275 56 35 7 597 7170 18 95 7 15 25 83 243 94 77 169 8 18 24 118 508 94 95 264 15 33 49 201 751 16 90 6 15 20 72 219 88 91 148 6 16 15 107 471 88 107 238 12 31 35 179 690 27 81 4 4 23 71 210 87 75 158 6 10 13 104 453 87 102 239 10 14 36 175 663 23 103 6 10 23 87 252 123 69 177 8 8 25 125 535 123 92 280 14 18 48 212 787 - 11 11 - 8 8 - 14 14 - 23 23 64 306 370 116 515 631 124 675 799 108 665 776 Heterosexual contact 91 84 175 155 135 290 209 229 438 210 211 421 Mother-to-child 10 13 23 8 12 20 16 20 36 18 21 39 Haemophiliac/transfusion recipient 2 3 5 1 0 1 1 1 2 0 0 0 Nosocomial infection 1 0 1 1 0 1 11 14 25 2 1 3 Other/undetermined 26 97 124 11 22 33 18 32 50 20 35 55 Injecting drug use Total East Total WHO European Region Transmission mode West Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total West Centre Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total Centre East Men who have sex with men 194 514 709 292 692 984 379 985 1364 358 956 1317 2726 7349 10077 2635 6936 9574 2472 6886 9365 2526 6742 9274 Female 2013 Male Total** Female 2014 Male Total** Female Cumulative total*** Male Unknown Total 130 841 16 4 2 83 1076 1357 464 1141 18 7 1 315 3303 1362 594 1982 34 11 3 398 4384 63 634 8 4 0 79 788 1006 288 886 3 3 1 238 2425 1006 351 1521 11 7 1 317 3214 0 24997 37381 1951 2007 47 3900 70283 101843 94344 48181 1930 5465 54 14299 266116 28 3 4 0 0 0 1 36 101835 119323 85491 3880 7472 101 18185 336287 34 106 13 1 5 55 214 179 126 231 12 2 6 135 691 179 160 337 25 3 11 190 905 19 121 4 4 6 63 217 193 144 227 5 2 9 135 715 193 163 348 9 6 15 198 932 0 579 1843 198 463 1308 1232 5623 2735 2141 3258 231 745 1653 2041 12804 2 0 2 1 0 0 1 6 2729 2698 5065 429 1208 2960 3260 18349 - 43 43 - 46 46 0 383 0 383 Injecting drug use 102 737 839 111 669 780 1288 7863 3 9153 Heterosexual contact 478 557 1035 459 627 1086 3590 3768 0 7358 19 27 46 9 16 25 147 191 0 338 Haemophiliac/transfusion recipient 1 1 2 0 1 1 8 14 0 22 Nosocomial infection 3 1 4 2 2 4 25 29 0 54 Other/undetermined 61 88 149 39 65 104 365 769 4 1137 Mother-to-child Total East 664 1454 2118 620 1426 2046 5423 13017 7 18445 Total WHO European Region 1954 5448 7407 1625 4566 6192 81329 291937 49 373081 * Data from Bosnia and Herzegovina, Russia, San Marino, Sweden, Turkmenistan, Ukraine and Uzbekistan excluded due to inconsistent reporting during the period. Therefore, totals by gender and overall may differ from totals presented in Tables 15-21. ** Annual totals include people diagnosed whose gender was unknown *** Cumulative total is the total number of cases reported by country since the start of reporting 74 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Female 2009 Male Total** Female 2010 Male Total** Female 2011 Male Total** Female 2012 Male Total** 231 1223 26 17 2 149 1648 1746 902 1643 29 18 3 459 4800 1747 1134 2866 55 35 5 609 6451 202 1291 22 7 5 127 1654 1738 748 1534 13 13 3 461 4510 1740 950 2825 35 20 8 588 6166 149 1042 16 5 1 101 1314 1581 677 1408 12 3 0 360 4041 1582 826 2450 28 8 1 461 5356 148 1077 15 8 1 112 1361 1503 569 1344 11 12 0 371 3810 1506 717 2421 26 20 1 483 5174 15 85 15 3 11 56 185 136 68 164 9 5 12 111 505 136 83 249 24 8 23 167 690 23 95 9 2 8 63 200 144 82 165 4 4 10 86 495 144 105 260 13 6 18 149 695 23 119 7 2 10 61 222 150 99 225 10 8 10 117 619 152 122 345 17 10 20 178 844 35 107 10 2 15 53 222 165 126 203 7 12 4 154 671 165 161 310 17 14 19 207 893 24 Transmission mode West Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total West Centre Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total Centre East Men who have sex with men - 14 14 - 29 29 - 32 32 - 24 134 808 942 146 994 1140 149 937 1086 106 900 1006 Injecting drug use 381 302 683 401 390 791 571 542 1113 521 524 1045 Heterosexual contact 13 12 25 16 16 32 14 26 40 9 13 2 1 3 0 1 1 0 1 1 1 0 1 Haemophiliac/transfusion recipient 2 3 5 1 4 5 1 2 3 1 1 2 Nosocomial infection 22 Mother-to-child 37 56 93 45 67 112 18 36 54 32 64 569 1196 1765 609 1501 2110 753 1576 2329 670 1526 2196 Total East 96 Other/undetermined 2402 6501 8906 2463 6506 8971 2289 6236 8529 2253 6007 8263 Total WHO European Region 75 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 23: AIDS diagnoses*, by sex, age and year of diagnosis (2005–2014) and cumulative totals Table 23a: EU/EEA and non-EU/EEA countries Age category EU/EEA <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown Total EU/EEA Non-EU/EEA <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown Total non-EU/EEA Total WHO European Region Age category EU/EEA <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown Total EU/EEA Non-EU/EEA <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown Female 2005 Male Total** Female 2006 Male Total** Female 2007 Male Total** Female 2008 Male Total** 77 78 154 363 924 617 293 1 2507 79 86 226 533 2350 2171 1199 5 6649 156 164 380 896 3275 2788 1492 6 9157 64 84 136 314 825 586 285 4 2298 67 86 192 525 2042 2051 1133 6 6102 131 170 328 840 2868 2638 1418 10 8403 56 75 115 275 703 546 272 1 2043 59 80 229 499 1827 1937 1151 3 5785 115 155 344 776 2533 2485 1423 4 7835 60 62 137 270 674 622 296 0 2121 74 69 213 479 1771 1910 1176 2 5694 134 131 350 749 2447 2533 1472 2 7818 13 5 18 46 84 39 14 0 19 2 22 98 278 185 95 1 32 7 41 144 362 224 109 1 9 2 24 72 144 61 23 2 14 3 24 125 401 184 80 3 23 5 48 197 545 245 103 5 38 11 36 82 150 84 28 0 43 11 41 160 499 248 99 0 81 22 77 242 649 332 127 0 19 6 34 78 179 66 22 1 25 11 51 132 467 261 101 0 44 17 85 211 648 327 123 1 219 700 920 337 834 1171 429 1101 1530 405 1048 1456 2726 7349 10077 2635 6936 9574 2472 6886 9365 2526 6742 9274 Female 2013 Male Total** Female 2014 Male Total** Female Cumulative total*** Male Unkown Total 28 29 81 130 366 343 295 0 1272 33 32 158 298 1058 1213 1060 1 3853 61 61 239 429 1425 1558 1356 1 5130 18 29 82 102 291 258 217 0 997 19 35 129 286 849 883 820 1 3022 37 64 211 388 1140 1141 1038 1 4020 4032 1216 5752 14914 28549 11436 6919 50 72868 4996 1914 12301 41617 112352 59921 36079 232 269412 0 1 0 9 16 6 2 1 35 9023 3121 18035 56498 140858 71314 42961 283 342093 36 9 32 92 266 155 91 1 45 8 41 153 657 471 216 4 81 17 73 245 923 626 307 5 19 6 26 76 191 169 141 0 30 20 75 167 498 453 300 2 49 26 101 243 689 622 441 2 310 93 628 1590 3532 1516 781 12 401 151 812 2985 9666 5617 2840 64 1 0 2 2 3 2 1 3 712 244 1441 4577 13197 7129 3621 79 Total non-EU/EEA 682 1595 2277 628 1545 2173 8462 22536 14 31000 Total WHO European Region 1954 5448 7407 1625 4566 6192 81329 291937 49 373081 * Data from Bosnia and Herzegovina, Russia, San Marino, Sweden, Turkmenistan, Ukraine and Uzbekistan excluded due to inconsistent reporting during the period. Therefore, totals by gender and overall may differ from totals presented in Tables 15-17. ** Annual totals include people diagnosed whose gender was unknown *** Cumulative total is the total number of cases reported by country since the start of reporting 76 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Female 2009 Male Total** Female 2010 Male Total** Female 2011 Male Total** Female 2012 Male Total** 52 49 105 222 600 517 265 0 1810 52 34 168 389 1571 1758 1167 0 5139 104 83 273 612 2172 2275 1432 0 6951 40 33 134 215 540 526 336 0 1824 30 18 198 389 1404 1637 1201 0 4877 70 51 332 604 1946 2163 1537 0 6703 31 29 123 169 450 430 258 1 1491 31 35 147 409 1307 1488 1088 3 4508 62 64 270 578 1758 1918 1346 4 6000 40 26 113 176 484 426 306 0 1571 27 40 192 375 1252 1398 1070 1 4355 67 66 305 553 1737 1824 1376 1 5929 18 13 58 112 238 111 41 1 20 13 47 186 617 343 131 5 38 26 105 298 855 455 172 6 20 9 42 113 279 118 57 1 24 17 73 222 730 395 166 2 44 26 115 335 1009 513 223 3 18 3 54 119 363 165 75 1 33 2 51 194 791 457 197 4 51 5 105 313 1154 623 272 7 19 2 35 108 282 172 64 0 33 3 36 156 691 522 211 1 52 5 71 264 973 694 275 1 592 1362 1955 639 1629 2268 798 1729 2530 682 1653 2335 Total non-EU/EEA 2402 6501 8906 2463 6506 8971 2289 6236 8529 2253 6007 8263 Total WHO European Region Age category EU/EEA <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown Total EU/EEA Non-EU/EEA <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown 77 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 23: AIDS diagnoses*, by sex, age and year of diagnosis (2004–2013) and cumulative totals Table 23b: West, Centre, East of the WHO European Region Age category West <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown Total West Centre <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown Total Centre Female 2005 Male Total** Female 2006 Male Total** Female 2007 Male Total** Female 2008 Male Total** 33 35 123 333 886 597 281 1 2289 33 37 190 465 2264 2135 1198 5 6327 66 72 313 798 3151 2732 1479 6 8617 27 31 120 287 804 581 270 4 2124 34 27 158 464 1943 2021 1121 5 5773 61 58 278 752 2748 2603 1391 9 7900 28 30 94 248 674 543 265 1 1883 29 34 180 423 1709 1912 1158 3 5448 57 64 274 673 2386 2457 1423 4 7338 20 27 102 241 641 603 281 1 1916 30 33 172 396 1632 1833 1154 1 5251 50 60 274 637 2275 2437 1435 2 7170 46 44 22 28 50 37 16 0 47 51 34 69 126 112 68 1 93 95 56 97 176 149 84 1 36 54 14 24 40 26 23 2 35 61 28 61 140 79 63 4 71 115 42 85 180 105 86 6 31 46 16 27 43 27 20 0 31 47 42 53 144 78 58 0 62 93 58 80 187 105 78 0 43 36 43 66 144 123 79 1 82 70 78 94 208 152 102 1 663 39 34 35 28 64 29 23 0 252 535 787 46 243 508 751 219 471 690 210 453 East <15 11 18 29 10 12 22 35 42 77 20 26 15–19 4 4 1 1 2 10 10 20 7 11 18 20–24 27 0 24 52 26 30 56 41 48 89 34 49 83 25–29 48 97 145 75 125 200 82 183 265 79 149 229 30–39 72 238 310 125 360 485 136 473 609 148 462 612 40–49 22 109 131 40 135 175 60 195 255 56 215 271 50+ 10 28 38 15 29 44 15 34 49 14 44 58 0 0 0 0 0 0 0 0 0 0 0 0 194 514 709 292 692 984 379 985 1364 358 956 1317 2726 7349 10077 2635 6936 9574 2472 6886 9365 2526 6742 9274 Female 2013 Male Total** Female 2014 Male Total** Female Cumulative total*** Male Unknown Total 10 18 58 96 307 315 272 0 1076 15 16 107 217 842 1102 1002 2 3303 25 34 165 314 1150 1419 1275 2 4384 6 12 42 81 236 225 186 0 788 4 21 78 174 625 769 753 1 2425 10 33 120 255 861 994 940 1 3214 2061 823 5424 14936 28803 11334 6852 50 70283 2469 1516 11725 41185 112617 60034 36340 230 266116 0 1 0 9 16 7 2 1 36 4529 2337 17140 56101 141401 71334 43164 281 336287 21 11 23 28 59 31 40 1 20 18 67 99 238 142 105 2 41 29 90 127 297 173 145 3 14 9 27 30 60 40 37 0 16 13 57 111 259 155 103 1 30 22 84 141 319 195 140 1 2072 409 511 575 1102 556 389 9 2637 454 870 1552 3546 2216 1477 52 1 0 0 0 0 1 1 3 4706 856 1371 2114 4621 2760 1857 64 217 715 932 5623 12804 6 18349 500 Unknown Total East Total WHO European Region Age category West <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown Total West Centre <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown Total Centre 214 691 905 East <15 33 43 76 17 29 46 209 291 0 15–19 9 6 15 14 21 35 77 95 0 172 20–24 32 25 57 39 69 108 445 518 2 965 25–29 98 135 233 67 168 235 993 1862 2 2857 30–39 266 635 901 186 463 649 2175 5852 3 8029 40–49 152 440 592 162 412 574 1062 3286 0 4347 74 169 243 135 263 398 459 1099 0 1558 0 1 1 0 1 1 3 14 0 17 Total East 664 1454 2118 620 1426 2046 5423 13017 7 18445 Total WHO European Region 1954 5448 7407 1625 4566 6192 81329 291937 49 373081 50+ Unknown * 78 Data from Bosnia and Herzegovina, Russia, San Marino, Sweden, Turkmenistan, Ukraine and Uzbekistan excluded due to inconsistent reporting during the period. Therefore, totals by gender and overall may differ from totals presented in Tables 15-17. ** Annual totals include people diagnosed whose gender was unknown *** Cumulative total is the total number of cases reported by country since the start of reporting HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Female 2009 Male Total** Female 2010 Male Total** Female 2011 Male Total** Female 2012 Male Total** 20 34 78 187 566 510 253 0 1648 26 18 131 335 1448 1696 1146 0 4800 46 52 209 523 2015 2207 1399 0 6451 21 23 97 190 501 493 329 0 1654 15 13 161 327 1258 1572 1164 0 4510 36 36 258 517 1761 2065 1493 0 6166 12 23 79 138 405 409 247 1 1314 10 26 110 313 1117 1420 1043 2 4041 22 49 189 451 1523 1829 1290 3 5356 14 16 76 144 427 399 285 0 1361 10 28 129 269 1046 1284 1043 1 3810 24 44 205 415 1474 1683 1328 1 5174 33 18 28 29 37 19 21 0 28 16 43 61 153 114 90 0 61 34 71 90 190 133 111 0 20 12 35 26 52 32 23 0 17 9 44 69 157 105 94 0 37 21 79 95 209 137 117 0 19 6 46 31 56 33 31 0 21 9 47 99 217 121 103 2 40 15 93 130 273 155 134 4 30 10 34 28 56 40 24 0 21 12 66 106 215 159 92 0 51 22 100 134 271 199 116 0 185 505 690 200 495 695 222 619 844 222 671 893 Total Centre 17 18 35 19 22 41 18 33 51 15 29 Age category West <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown Total West Centre <15 15–19 20–24 25–29 30–39 40–49 50+ Unknown East 44 <15 10 13 23 7 13 20 3 2 5 2 3 5 15–19 57 41 98 44 66 110 52 41 93 38 33 71 20–24 118 179 297 112 215 327 119 191 310 112 156 268 25–29 235 587 822 266 719 985 352 764 1116 283 682 965 30–39 99 291 390 119 355 474 153 404 557 159 476 635 40–49 32 62 94 41 109 150 55 138 193 61 146 207 50+ 1 5 6 1 2 3 1 3 4 0 1 569 1196 1765 609 1501 2110 753 1576 2329 670 1526 2196 Total East 1 Unknown 2402 6501 8906 2463 6506 8971 2289 6236 8529 2253 6007 8263 Total WHO European Region 79 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 24: The most common AIDS-indicative diseases diagnosed in 2014, ordered by frequency Table 24a: EU/EEA and non-EU/EEA countries Men N Diseases EU/EEA Pneumocystis pneumonia Candidiasis, oesophageal Mycobacterium tuberculosis, pulmonary in an adult or an adolescent (aged 13 years or over) Wasting syndrome due to HIV Kaposi’s sarcoma Toxoplasmosis of brain in a patient over one month of age Mycobacterium tuberculosis, extrapulmonary Cytomegalovirus disease (other than liver, spleen or nodes) in a patient over one month of age Encephalopathy, HIV-related Cryptococcosis, extrapulmonary Non-EU/EEA Mycobacterium tuberculosis, pulmonary in an adult or an adolescent (aged 13 years or over) Mycobacterium tuberculosis, extrapulmonary Wasting syndrome due to HIV Candidiasis, oesophageal Pneumocystis pneumonia Pneumonia, recurrent in an adult or an adolescent (aged 13 years or over) Encephalopathy, HIV-related Candidiasis of bronchi, trachea or lungs Isosporiasis, intestinal with diarrhoea (>1 months duration) Bacterial infections, multiple or recurrent in a child under 13 years of age % 837 368 22.4 9.8 Women N 227 139 % 18.6 11.4 Total N % 1064 507 21.5 10.2 Children N 3 3 % 4.7 4.7 370 9.9 127 10.4 497 10.0 9 14.1 346 304 176 165 9.3 8.1 4.7 4.4 133 23 127 87 10.9 1.9 10.4 7.1 479 327 303 252 9.7 6.6 6.1 5.1 14 0 1 5 21.9 0.0 1.6 7.8 205 5.5 45 3.7 250 5.0 1 1.6 137 85 3.7 2.3 65 21 5.3 1.7 202 106 4.1 2.1 10 1 15.6 1.6 422 26.3 124 21.0 546 24.9 9 15.8 164 145 104 86 50 49 38 36 23 10.2 9.1 6.5 5.4 3.1 3.1 2.4 2.2 1.4 44 61 52 27 15 15 16 17 11 7.5 10.3 8.8 4.6 2.5 2.5 2.7 2.9 1.9 208 206 156 113 65 64 54 53 34 9.5 9.4 7.1 5.2 3.0 2.9 2.5 2.4 1.6 9 4 3 1 1 1 4 5 6 15.8 7.0 5.3 1.8 1.8 1.8 7.0 8.8 10.5 Table 24b: West, Centre, East of the WHO European Region Diseases West Pneumocystis pneumonia Candidiasis, oesophageal Kaposi’s sarcoma Wasting syndrome due to HIV Mycobacterium tuberculosis, pulmonary in an adult or an adolescent (aged 13 years or over) Toxoplasmosis of brain in a patient over one month of age Cytomegalovirus disease (other than liver, spleen or nodes) in a patient over one month of age Mycobacterium tuberculosis, extrapulmonary Encephalopathy, HIV-related Cryptococcosis, extrapulmonary Centre Wasting syndrome due to HIV Mycobacterium tuberculosis, pulmonary in an adult or an adolescent (aged 13 years or over) Candidiasis, oesophageal Pneumocystis pneumonia Encephalopathy, HIV-related Pneumonia, recurrent in an adult or an adolescent (aged 13 years or over) Toxoplasmosis of brain in a patient over one month of age Mycobacterium tuberculosis, extrapulmonary Kaposi’s sarcoma Cytomegalovirus disease (other than liver, spleen or nodes) in a patient over one month of age East Mycobacterium tuberculosis, pulmonary in an adult or an adolescent (aged 13 years or over) Mycobacterium tuberculosis, extrapulmonary Wasting syndrome due to HIV Candidiasis, oesophageal Pneumocystis pneumonia Candidiasis of bronchi, trachea or lungs Encephalopathy, HIV-related Isosporiasis, intestinal with diarrhoea (>1 months duration) Pneumonia, recurrent in an adult or an adolescent (aged 13 years or over) Cryptococcosis, extrapulmonary 80 Men N 757 287 278 199 % 25.8 9.8 9.5 6.8 Women N 201 103 21 75 % 21.5 11.0 2.2 8.0 Total N 958 390 299 274 % 24.8 10.1 7.7 7.1 Children N 2 1 0 1 % 15.4 7.7 0.0 7.7 189 6.5 81 8.6 270 7.0 1 7.7 139 4.7 110 11.7 249 6.4 0 0.0 188 6.4 43 4.6 231 6.0 1 7.7 130 88 69 4.4 3.0 2.4 73 37 14 7.8 3.9 1.5 203 125 83 5.3 3.2 2.1 2 1 1 15.4 7.7 7.7 178 18.8 65 21.7 243 19.5 13 24.1 159 16.8 33 11.0 192 15.4 8 14.8 105 110 49 44 34 34 36 11.1 11.6 5.2 4.7 3.6 3.6 3.8 32 25 29 11 17 12 2 10.7 8.4 9.7 3.7 5.7 4.0 0.7 137 135 78 55 51 46 38 11.0 10.9 6.3 4.4 4.1 3.7 3.1 3 1 9 7 1 4 0 5.6 1.9 16.7 13.0 1.9 7.4 0.0 27 2.9 3 1.0 30 2.4 0 0.0 444 30.3 137 23.8 581 28.5 9 16.7 165 113 80 55 50 49 34 38 27 11.3 7.7 5.5 3.8 3.4 3.3 2.3 2.6 1.8 46 54 56 28 24 14 16 9 13 8.0 9.4 9.7 4.9 4.2 2.4 2.8 1.6 2.3 211 167 136 83 74 63 50 47 40 10.3 8.2 6.7 4.1 3.6 3.1 2.5 2.3 2.0 8 4 2 1 4 1 5 1 0 14.8 7.4 3.7 1.9 7.4 1.9 9.3 1.9 0.0 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 25: Deaths among people diagnosed with HIV and/or AIDS, by country and year of death (2005–2014) and cumulative totals in EU/EEA and other countries of the WHO European Region* Area EU/EEA West West Centre Centre Centre Centre West East West West West West Centre West West West East Country** Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein East Lithuania West Luxembourg West Malta West Netherlands West Norway Centre Poland West Portugal Centre Romania Centre Slovakia Centre Slovenia West Spain West Sweden West United Kingdom Total EU/EEA Non-EU/EEA Centre Albania West Andorra East Armenia East Azerbaijan East Belarus Centre Bosnia and Herzegovina Yugoslav Republic of Centre former Macedonia, the East Georgia West Israel East Kazakhstan East Kyrgyzstan East Moldova West Monaco Centre Montenegro East Russia West San Marino Centre Serbia West Switzerland East Tajikistan Centre Turkey East Turkmenistan East Ukraine East Uzbekistan Total non-EU/EEA WHO European Region West Centre East Total WHO European Region 2005 2006 2007 2008 51 46 12 3 7 10 27 12 400 156 49 6 0 8 862 35 0 5 3 1 94 15 65 300 223 0 2 1205 19 359 3975 36 34 8 6 4 6 19 18 332 164 38 7 1 8 812 40 0 9 6 7 64 6 43 240 186 4 0 1032 8 314 3452 51 32 6 2 3 11 20 11 243 172 42 12 0 6 819 47 0 15 3 1 101 1 61 225 156 3 3 1010 6 314 3376 29 26 9 7 5 0 8 20 78 3 9 0 15 21 138 5 7 0 20 43 141 1 Year of diagnosis 2009 2010 39 19 14 10 3 10 3 2 207 113 48 15 0 5 645 57 0 12 1 0 64 2011 2012 2013 2014 Cumulative total*** 25 28 16 8 5 14 2 5 152 84 50 11 1 1 636 88 0 10 7 2 84 1 57 174 186 3 1 307 156 2114 34 33 14 8 3 12 4 2 122 102 42 11 0 0 107 0 18 3 0 80 2 46 205 199 0 5 248 157 1457 29 33 13 4 2 14 0 2 70 60 44 19 0 0 106 0 16 1 1 65 3 35 126 237 0 3 143 131 1131 1428 2031 156 181 112 228 2028 108 0 36302 14553 1846 393 39 414 43029 748 6 172 132 61 1488 628 1272 8536 4010 39 97 48070 1323 16168 185572 13 0 38 47 188 0 10 0 40 30 126 2 13 0 46 36 18 0 136 1 326 416 1423 57 14 3 8 230 129 31 11 0 3 754 58 0 20 4 0 95 3 71 209 144 0 5 852 308 3023 32 27 2 7 3 11 9 0 179 126 30 11 0 5 715 69 0 17 3 0 96 3 46 210 120 2 1 534 280 2538 53 214 134 1 2 423 310 2404 34 31 17 6 4 13 6 7 169 121 53 17 1 4 644 80 0 9 3 1 82 1 68 200 215 1 1 370 158 2316 3 1 32 43 146 0 13 0 40 27 151 1 12 0 23 45 146 0 11 0 26 40 158 0 4 5 2 1 0 1 4 0 3 0 64 56 30 77 24 41 0 0 0 25 71 0 4 2188 9 2643 36 37 86 16 45 1 1 0 24 57 11 2 2420 9 2938 67 39 91 18 68 0 2 0 13 50 13 0 2507 19 3101 74 30 137 15 65 0 1 0 22 34 30 0 2710 124 3468 63 23 130 21 54 0 2 0 25 41 34 0 2591 40 3256 80 23 168 26 72 0 4 0 29 23 53 0 3096 66 3867 94 32 150 19 127 0 2 0 30 13 61 0 3744 4511 83 22 148 19 11 0 1 0 18 3 86 0 3870 4547 82 28 147 6 22 0 1 0 20 4 98 10 3514 4143 68 26 108 9 33 0 2 12 4 73 11 3436 3895 828 920 1439 198 697 18 41 0 8 1080 5891 463 95 1 35443 323 49868 3696 369 2553 6618 3216 310 2864 6390 3135 282 3060 6477 2741 288 3462 6491 2313 244 3237 5794 2137 288 3846 6271 1923 389 4515 6827 1735 333 4593 6661 1064 344 4192 5600 736 365 3951 5052 184914 7961 42585 235466 * Comparisons between country data should be made with caution. Some country data include only AIDS-related deaths while other country data include data for all deaths among people diagnosed with HIV and/or AIDS, irrespective of the cause of death. ** Country-specific comments are in Annex 5 *** Cumulative total is the total number of cases reported by country since the start of reporting 81 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 26: Deaths among AIDS cases*, by transmission mode and year of death (2005–2014) and cumulative totals Table 26a: EU/EEA and non-EU/EEA countries Transmission mode EU/EEA Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total EU/EEA Non-EU/EEA Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total non-EU/EEA Total WHO European Region Transmission mode EU/EEA Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total EU/EEA Non-EU/EEA Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total non-EU/EEA Total WHO European Region * Female 2005 Male Total** Female 2006 Male Total** Female 2007 Male Total** Female 2008 Male Total** 221 330 10 19 25 66 671 586 1011 543 17 31 35 199 2422 586 1232 873 27 50 60 265 3093 186 289 6 11 22 58 572 494 853 471 10 26 39 167 2060 494 1039 760 16 37 61 225 2632 194 286 3 10 25 61 579 489 834 445 12 14 26 152 1972 489 1028 731 15 24 51 213 2551 184 262 3 7 19 69 544 434 693 380 14 27 22 155 1725 434 877 642 17 34 41 224 2269 25 47 3 0 1 15 91 762 30 164 72 4 3 1 78 352 2774 30 189 119 7 3 2 93 443 3536 55 71 0 0 1 6 133 705 24 229 103 2 2 0 11 371 2431 24 284 174 2 2 1 17 504 3136 61 74 4 1 0 3 143 722 16 276 108 4 4 3 20 431 2403 16 337 182 8 5 3 23 574 3125 54 98 4 0 0 7 163 707 23 289 138 5 1 0 14 470 2195 23 344 236 9 1 0 21 634 2903 Female 2013 Male Total** Female 2014 Male Total** Female Cumulative total*** Male Unkown Total 93 180 5 10 18 59 365 312 333 310 4 15 16 102 1092 312 426 490 9 25 34 161 1457 52 140 3 7 16 38 256 254 245 223 3 14 22 107 868 255 297 364 6 21 38 145 1126 0 9938 10110 683 1436 643 1709 24519 50045 40236 14537 776 4042 935 6336 116907 2 0 1 0 0 0 0 3 50022 50118 24568 1457 5474 1562 8013 141214 49 96 6 0 0 10 161 526 21 250 165 7 0 0 23 466 1558 21 299 261 13 0 0 33 627 2084 20 91 2 0 1 6 120 376 22 176 118 1 0 0 22 339 1207 22 196 209 3 0 1 28 459 1585 0 1415 1687 84 63 4 168 3421 27940 2514 5032 2199 93 203 5 575 10621 127522 0 1 0 1 0 0 4 6 9 2513 6447 3878 178 266 9 745 14036 155244 Data from Bosnia and Herzegovina, Finland, Italy, Russia, San Marino, Sweden, Turkmenistan, Ukraine and Uzbekistan excluded due to inconsistent reporting during the period. Therefore, totals by gender and overall may differ from totals presented in Table 25. ** Annual totals include people diagnosed whose gender was unknown *** Cumulative total is the total number of cases reported by country since the start of reporting 82 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Female 2009 Male Total** Female 2010 Male Total** Female 2011 Male Total** Female 2012 Male Total** 116 240 6 9 15 61 447 389 508 310 7 12 23 127 1376 389 624 550 13 21 38 188 1823 94 221 12 5 14 44 390 403 413 355 2 20 21 155 1369 403 507 576 14 25 35 199 1759 96 213 5 8 28 63 413 383 374 331 9 18 19 125 1259 383 470 544 14 26 47 188 1672 103 170 5 9 25 40 352 328 320 302 5 19 21 130 1125 329 423 472 10 28 46 170 1478 52 116 3 0 1 7 179 626 23 275 126 2 0 1 18 445 1821 23 327 242 5 0 2 25 624 2447 53 124 2 1 0 9 189 579 24 330 143 3 1 0 15 516 1885 24 383 267 5 2 0 24 705 2464 46 165 3 0 0 8 222 635 18 311 187 8 1 0 20 545 1804 18 357 352 11 1 0 28 767 2439 47 117 4 1 0 2 171 523 12 318 162 2 0 0 12 506 1631 12 365 279 6 1 0 14 677 2155 Transmission mode EU/EEA Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total EU/EEA Non-EU/EEA Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total non-EU/EEA Total WHO European Region 83 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 26: Deaths among AIDS cases*, by transmission mode and year of death (2005–2014) and cumulative totals Table 26b: West, Centre, East of the WHO European Region Transmission mode West Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total West Centre Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total Centre East Men who have sex with men Female 2005 Male Total** Female 2006 Male Total** Female 2007 Male Total** Female 2008 Male Total** 215 303 11 8 1 31 569 582 974 507 11 16 1 155 2246 582 1189 810 22 24 2 186 2815 177 276 4 5 2 35 499 492 809 442 5 20 0 129 1897 492 986 718 9 25 2 164 2396 187 271 3 5 1 35 502 470 764 436 7 8 0 123 1808 470 951 707 10 13 1 158 2310 174 244 3 6 1 38 466 413 620 351 12 18 1 106 1521 413 794 595 15 24 2 144 1987 7 41 0 11 24 35 118 29 41 65 7 18 34 54 248 29 48 106 7 29 58 89 366 6 33 2 6 20 24 91 24 31 65 6 8 39 41 214 24 37 98 8 14 59 65 305 9 23 1 6 24 25 88 32 38 49 5 9 26 34 193 32 47 72 6 15 50 59 281 8 26 1 1 18 31 85 35 38 50 3 10 21 46 203 35 46 76 4 11 39 77 288 - 5 5 - 2 2 3 9 160 184 58 242 300 308 367 56 9 24 59 3 Injecting drug use 324 381 Heterosexual contact 207 33 43 76 51 67 118 66 68 134 90 117 Mother-to-child 2 3 5 0 1 1 3 4 7 3 4 7 Haemophiliac/transfusion recipient 0 0 0 0 0 0 0 1 1 0 0 0 Nosocomial infection 1 1 2 1 0 1 0 3 3 0 0 0 Other/undetermined 15 68 83 5 8 13 4 15 19 7 17 24 Total East 75 280 355 115 320 435 132 402 534 156 471 628 762 2774 3536 705 2431 3136 722 2403 3125 707 2195 2903 Female 2013 Male Total** Female 2014 Male Total** Female Cumulative total*** Male Unkown Total 69 134 0 6 0 17 226 280 250 237 1 7 0 63 838 280 319 371 1 13 0 80 1064 36 94 1 1 0 10 142 225 166 148 1 5 0 47 592 226 202 243 2 6 0 57 736 0 10516 10118 660 1261 20 1262 23837 51263 40960 14358 708 3783 18 5746 116836 2 0 1 0 0 0 0 3 51242 51442 24425 1368 5043 38 6996 140554 13 35 7 4 18 35 112 41 41 80 3 8 16 41 230 41 54 115 10 12 34 76 342 9 44 2 6 16 27 104 47 51 71 2 9 22 59 261 47 60 115 4 15 38 86 365 0 274 674 79 237 623 473 2360 1179 1059 1122 120 458 917 782 5637 0 0 0 1 0 0 1 2 1176 1314 1762 198 692 1524 1238 7904 60 12 12 4 0 116 0 116 292 352 27 4 Injecting drug use 204 231 563 3246 1 3806 Heterosexual contact Total WHO European Region Transmission mode West Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total West Centre Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total Centre East Men who have sex with men 107 158 265 93 122 215 1005 1254 0 2257 Mother-to-child 4 7 11 2 1 3 28 41 0 69 Haemophiliac/transfusion recipient 0 0 0 0 0 0 1 4 0 5 Nosocomial infection 0 0 0 1 0 1 4 5 0 9 Other/undetermined 17 21 38 7 23 30 142 383 3 524 Total East 188 490 678 130 354 484 1743 5049 4 6786 Total WHO European Region 526 1558 2084 376 1207 1585 27940 127522 9 155244 * Data from Bosnia and Herzegovina, Finland, Italy, Russia, San Marino, Sweden, Turkmenistan, Ukraine and Uzbekistan excluded due to inconsistent reporting during the period. Therefore, totals by gender and overall may differ from totals presented in Table 25. ** Annual totals include people diagnosed whose gender was unknown *** Cumulative total is the total number of cases reported by country since the start of reporting 84 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Female 2009 Male Total** Female 2010 Male Total** Female 2011 Male Total** Female 2012 Male Total** 108 227 5 6 2 34 382 371 452 284 4 8 2 95 1216 371 560 511 9 14 4 129 1598 81 202 7 3 0 24 317 369 371 309 2 9 0 115 1175 369 452 511 9 12 0 139 1492 75 167 3 4 0 23 272 345 309 253 4 13 0 83 1007 345 384 420 7 17 0 106 1279 77 138 4 1 1 12 233 299 239 254 2 7 0 64 865 300 316 392 6 8 1 76 1099 6 26 2 3 13 23 73 37 28 41 4 4 21 35 170 37 34 67 6 7 34 58 243 8 28 6 3 14 20 79 54 23 56 0 12 21 43 209 54 31 84 6 15 35 63 288 13 54 2 4 28 36 137 49 42 83 7 5 19 47 252 49 55 137 9 9 47 83 389 16 25 3 8 24 25 101 35 45 54 3 12 21 62 232 35 61 79 6 20 45 87 333 6 Transmission mode West Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total West Centre Men who have sex with men Injecting drug use Heterosexual contact Mother-to-child Haemophiliac/transfusion recipient Nosocomial infection Other/undetermined Total Centre East Men who have sex with men - 4 4 - 4 4 - 7 7 - 6 54 303 357 58 349 407 54 334 388 57 354 411 Injecting drug use 103 111 214 115 133 248 157 182 339 124 156 280 Heterosexual contact 2 1 3 1 3 4 3 6 9 2 2 0 0 0 0 0 0 0 1 1 1 0 1 Haemophiliac/transfusion recipient 1 1 2 0 0 0 0 0 0 0 0 0 Nosocomial infection 4 Mother-to-child 11 15 26 9 12 21 12 15 27 5 16 171 435 606 183 501 684 226 545 771 189 534 723 Total East 21 Other/undetermined 626 1821 2447 579 1885 2464 635 1804 2439 523 1631 2155 Total WHO European Region 85 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Table 27: Number of HIV tests performed, excluding unlinked anonymous testing and testing of blood donations, by country and year (2005–2014) and number of tests per 1 000 population in 2014, in EU/EEA and other countries of the WHO European Region Area EU/EEA West West Centre Centre Centre Centre West East West West West West Centre West West West East Country* Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece** Hungary Iceland Ireland Italy Latvia Liechtenstein East Lithuania West Luxembourg West Malta West Netherlands West Norway Centre Poland West Portugal Centre Romania Centre Slovakia Centre Slovenia West Spain West Sweden West United Kingdom Non-EU/EEA Centre Albania West Andorra East Armenia East Azerbaijan East Belarus Centre Bosnia and Herzegovina Yugoslav Republic Centre former of Macedonia, the East Georgia West Israel East Kazakhstan East Kyrgyzstan East Moldova West Monaco Centre Montenegro East Russia West San Marino Centre Serbia West Switzerland East Tajikistan Centre Turkey East Turkmenistan East Ukraine East Uzbekistan * ** 86 Number of HIV tests 2009 2010 2005 2006 2007 2008 667825 591193 110000 26085 38708 330233 143671 61249 142427 5442919 70512 9397 85538 58424 13975 6197 193075 136040 917117 188279 103718 24522 - 659693 578717 105000 26124 37763 317823 154332 65861 147601 5181244 80168 9106 85117 52988 14339 10309 188550 159180 191223 93426 25624 - 777935 595394 160000 32698 41913 344874 141880 68478 153478 5157143 33558 65980 9351 63000 79279 60333 13379 11957 176728 220226 88520 31120 - 751749 619418 110000 38996 42294 342223 124935 74357 186822 5055365 29908 83408 9522 72444 162381 13366 181118 282248 66926 31183 - 770901 635150 140000 40938 48158 347135 112533 78735 190380 5026694 35171 91181 7794 184980 59331 100799 13308 213138 284053 132990 37105 - 3700 1884 39469 237027 440675 10834 3098 3077 50221 237183 441299 20904 1686 3546 55342 293086 437983 16858 2458 2803 60701 322525 430175 - 2143 2810 60103 340048 459032 - Tests/1000 2014 population 2011 2012 2013 831675 651095 160000 32848 48385 353507 168923 78054 185114 5011668 31070 89137 7318 180055 58826 178554 8533 229783 291915 109261 36977 - 826256 679655 180000 32928 49074 334569 137877 85025 5216466 31918 84464 184521 58799 102234 57685 317286 306679 110025 38110 - 703486 190000 40071 54120 349205 134709 73367 5247398 34622 93060 175488 60491 101042 64778 358953 293204 110506 33602 - 695433 210000 29998 50235 341583 137151 82279 5225638 32241 95861 150597 58302 102161 68020 14522 302898 114574 33457 - 697684 230000 349448 82266 5266055 22455 168028 60614 108781 332422 126187 35498 - 62.3 31.7 33.2 62.5 80 2.1 36.5 30.3 37 16.7 23.2 17.2 - 2168 2678 60731 353772 517625 20793 3260 2590 68449 365090 621780 - 3140 2062 71957 514434 683125 - 3063 2310 83431 482282 770136 - 2378 94122 612860 1157072 - 31.2 31.3 63.6 121.8 - 7526 11172 10574 10426 11842 18721 17811 18105 24562 - - 26026 234835 621261 162075 185922 3594 17744347 4723 35083 72114 1881750 153090 1555511 515972 16989 242484 862058 179407 216566 3988 18535043 5061 37829 91310 1908257 136145 1661600 545240 16989 269071 1491190 227879 347709 3838 3976 42573 92474 1998163 211789 1937440 619130 18792 271641 1643938 268134 355711 4229 3825 44555 129330 5045319 2280442 796371 17562 278887 1758026 325855 342666 5812 4181 47734 214207 2347084 987464 25370 286995 1786289 297959 336871 6492 25209546 5090 51727 280281 2319946 1506724 21799 274294 1897476 381295 340397 6914 3961 56086 438532 2392970 - 15562 233516 2026174 470355 342418 6781 3845 64031 447636 2343099 - 18091 2127136 370160 146105 6970 4004 65829 514701 2155108 2941748 - 86290 2190757 410331 133476 6571 3427 56282 634791 2027295 1853626 - 21.4 126.1 70.2 32.8 10.5 102.1 7.9 76.5 28.1 43.3 - Country-specific comments are in Annex 5 HIV tests reported for Greece refer to only to those performed in reference centres and do not include all tests carried out in public hospitals or private laboratories. SURVEILLANCE REPORT HIV/AIDS surveillance in Europe 2014 Maps 87 HIV/AIDS surveillance in Europe 2014 Map 1: New HIV diagnoses per 100 000 population, 2014 <2 2 to < 10 10 to < 20 ≥ 20 Missing or excluded data Andorra Liechtenstein Luxembourg Malta Monaco San Marino Map 2: New HIV diagnoses in men per 100 000 male population, 2014 <2 2 to < 10 10 to < 20 ≥ 20 Missing or excluded data Andorra Liechtenstein Luxembourg Malta Monaco San Marino 88 SURVEILLANCE REPORT SURVEILLANCE REPORT HIV/AIDS surveillance in Europe 2014 Map 3: New HIV diagnoses in women per 100 000 female population, 2014 <2 2 to < 10 10 to < 20 ≥ 20 Missing or excluded data Andorra Liechtenstein Luxembourg Malta Monaco San Marino Map 4: New HIV diagnoses in men who have sex with men per 100 000 male population, 2014 <1 1 to < 3 3 to < 5 ≥5 Missing or excluded data Andorra Liechtenstein Luxembourg Malta Monaco San Marino 89 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Map 5: New HIV diagnoses acquired through injecting drug use per 100 000 population, 2014 <1 1 to < 3 3 to < 5 ≥5 Missing or excluded data Andorra Liechtenstein Luxembourg Malta Monaco San Marino Map 6: New HIV diagnoses acquired through heterosexual transmission per 100 000 population, 2014 <1 1 to < 3 3 to < 5 ≥5 Missing or excluded data Andorra Liechtenstein Luxembourg Malta Monaco San Marino 90 SURVEILLANCE REPORT HIV/AIDS surveillance in Europe 2014 Map 7: Percentage of adult (>14 years) HIV diagnoses with CD4 <350 cells/mm3 at diagnosis, 2014 < 30% 30% to < 40% 40% to < 50% ≥ 50% Missing or excluded data Andorra Liechtenstein Luxembourg Malta Monaco San Marino Map 8: AIDS diagnoses reported per 100 000 population, 2014 <1 1 to < 3 3 to < 5 ≥5 Missing or excluded data Andorra Liechtenstein Luxembourg Malta Monaco San Marino 91 HIV/AIDS surveillance in Europe 2014 92 SURVEILLANCE REPORT SURVEILLANCE REPORT HIV/AIDS surveillance in Europe 2014 Annexes 93 SURVEILLANCE REPORT HIV/AIDS surveillance in Europe 2014 Annex 1: Framework for data collection, validation and presentation Since 2008, the European Centre for Disease Prevention and Control (ECDC) and the World Health Organization Regional Office for Europe (WHO Regional Office) have jointly carried out the enhanced surveillance of HIV/ AIDS in Europe. Both strive to ensure a high quality of standardised HIV and AIDS surveillance data from the 53 countries of the WHO European Region, including the 28 countries of the European Union (EU) and the three countries of the European Economic Area (EEA) (in this report referred to together as EU/EEA). 1 Reporting In EU/EEA countries, the Member States’ Coordinating Competent Bodies have nominated national operational contact points for HIV/AIDS surveillance to work on reporting surveillance data to the joint ECDC/WHO database for HIV/AIDS surveillance. For non-EU/EEA countries, nominations for national HIV/AIDS surveillance focal points were received directly by the WHO Regional Office via the respective ministries of health. Data are submitted through a web-based platform to a joint database of The European Surveillance System (TESSy). Four types of data are collected: HIV (case-based and aggregate), AIDS (case-based and aggregate), HIVAIDS (case-based data which links HIV and AIDS diagnoses) and number of HIV tests performed (aggregate). Data are uploaded directly by the reporting country into the database. When uploading data, a built-in set of validation rules ensures the verification of the data within the database. This verification of the data during the uploading process improves the quality of the data and allows each country to test their datasets prior to submission. Further validation checks are carried out before the data is considered of sufficient quality to be used for analysis. Bosnia and Herzegovina, Russia, Turkmenistan and Uzbekistan did not report any HIV data through this system for 2014. HIV data for Russia were therefore obtained through publicly available national sources, with the assumption that the data has been validated to the same rigor as for the other countries, and then incorporated with the other countries’ reported data to enable a more complete presentation of the epidemiology of HIV and AIDS in Europe. Bosnia and Herzegovina, Russia, San Marino, Sweden, Turkmenistan and Uzbekistan did not report any AIDS data through this system for 2014. Surveillance systems – data sources To describe the national source of data and specify the national surveillance system from which the reported data originate, the variable ‘data source’ is included as a compulsory part of reporting (Annexes 4 and 4a). Some cross-country comparisons are hampered by differences in surveillance systems as the quality and coverage of national surveillance are not consistent. Particularly in the early part of the period covered in this report (2005– 2014), some countries did not have national HIV/AIDS data and others established or substantially modified the national reporting systems over the course of the reporting period. These issues are detailed in Annex 5. 2 Data collection and validation Data collection 2015 The 2014 data submission for HIV and AIDS surveillance took place between 15 March and 15 September 2015. Data presented in this report were extracted from the joint database on 5 November 2015, although minor corrections were made during subsequent country reviews and verification of the data presented in the draft report. Individual country datasets Data were uploaded, validated and approved in the joint database for HIV/AIDS surveillance by the reporting countries. Once the data were submitted, individual datasets were validated. The HIVAIDS record type was used for the first time in 2014 to collected case-based joined HIV and AIDS data. Thirty-three countries used the joined record type for 2014 reporting and, of these, twenty-eight countries uploaded all historical data in the new format, two countries uploaded several years of data in the new format, and three countries uploaded only 2014 data in the new format. Two countries (Kazakhstan and Ukraine) reported aggregated HIV data. Ukraine reported aggregated AIDS data for the years 2005 to 2014 and Belarus reported aggregate AIDS data for 2014. All other countries reported case-based AIDS data. Reporting of aggregated HIV and AIDS data has an impact on the data presentation and analysis and the epidemiological overview of HIV/AIDS in Europe because fewer variables are available from the aggregated datasets, hence reducing the amount of data that can be presented in certain tables and figures. 3 Data re-coding and adjustments Dates used for data presentation In this report the HIV and AIDS data are presented by ‘date of diagnosis’ with the exception of Table 1a. If countries could not provide this date, the ‘date of notification’ or ‘date of statistics’ was used instead. 95 HIV/AIDS surveillance in Europe 2014 Region of origin When available, countries were encouraged to provide data on the specific country of origin or nationality of the case. This information was used first and, if absent, the variable ‘region of origin’ was used to group cases into region of origin presented in Table 11 (stratified by reporting country) and Table 12 (all countries stratified by mode of transmission). Origin of reported cases Cases originating from countries outside of the reporting country, including those from outside of Europe or from countries with generalised HIV epidemics are, on occasion, separated from other cases for the analyses presented here. This approach has been taken so as to inform epidemiological understanding and to guide public health resource allocation and prevention efforts. In order to compare the impact of the epidemic on all transmission modes, cases reported as originating from regions or countries of sub-Saharan Africa were used as a proxy for cases originating from countries with a generalised epidemic (in Tables 11, 12 and in selected Figures). As most of the cases originating from SURVEILLANCE REPORT sub-Saharan Africa were reported from west European countries within the EU/EEA, this information is presented in detail in Chapter 1. Reporting delay Reporting delays refer to the time delay between HIV/ AIDS diagnosis (or death) and the report of this event at national level, identified by ‘date of notification’. Due to delays in reporting, HIV trends analysed at a European level are often biased downwards for the most recent year (2014) and, to a lesser extent for the 2 to 3 years prior to the reporting period. To provide a more accurate picture of trends, surveillance data should be corrected to more accurately describe the trends in HIV diagnoses. In this report, we apply a statistical approach, as described by Heisterkamp, et al [1] to adjust the surveillance data for reporting delays. Annual reporting delay probabilities were estimated using historical data from 2005 to 2014. Countries were excluded from reporting delay adjustment: 1 when they showed an inconsistent and non-stationary pattern in their reporting delay distribution during the period 2005–2014, or Figure A1: Geographical/epidemiological division of the WHO European Region West Centre East Andorra Luxembourg Malta Monaco San Marino The countries covered by the report are grouped as follows: • West, 23 countries: Andorra, Austria*, Belgium*, Denmark*, Finland*, France*, Germany*, Greece*, Iceland, Ireland*, Israel, Italy*, Luxembourg*, Malta*, Monaco, Netherlands*, Norway, Portugal*, San Marino, Spain*, Sweden*, Switzerland, United Kingdom*. • Centre, 15 countries: Albania, Bosnia and Herzegovina, Bulgaria*, Croatia*, Cyprus*, Czech Republic*, Hungary*, the former Yugoslav Republic of Macedonia, Montenegro, Poland*, Romania*, Serbia, Slovakia*, Slovenia*, Turkey. • East, 15 countries: Armenia, Azerbaijan, Belarus, Estonia*, Georgia, Kazakhstan, Kyrgyzstan, Latvia*, Lithuania*, Moldova, Russia, Tajikistan, Turkmenistan, Ukraine, Uzbekistan. * Countries which constitute the European Union as of 1 July 2014. 96 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT 2 when they reported aggregated data during the period 2005–2014. maps presenting figures for MSM, rates are calculated using the male population. Adjusting for reporting delays is a valuable tool to indicate HIV trends more precisely, as well as in monitoring the timeliness of data collection, an important aspect of quality control. Data are presented by year but also as cumulative totals per country. The cumulative total includes all data reported by that particular country since the beginning of national reporting and is not limited to the selected number of years presented. Reporting delays were applied for the graphs showing trends for the EU/EEA and by transmission mode. The list of countries with the number of reported diagnoses adjusted for reporting delay are presented in Annex 6. 4 Data presentation Geographical presentation Data are presented for the WHO European Region and the EU/EEA. The EU comprises 28 Member States and the EEA comprises an additional three countries (Norway, Iceland and Liechtenstein) which are included in the overview of the EU/EEA. The tables are presented by EU/EEA countries, non-EU/ EEA countries, by individual countries and by totals. The 53 countries of the WHO European Region are also subdivided into three geographical areas based on epidemiological considerations and in accordance with the division used in previous reports on HIV/AIDS surveillance in Europe: West (23 countries), Centre (15 countries) and East (15 countries) (see Figure A1). The division reflects similarities in epidemiological dynamics such as epidemic levels, trends over time and transmission patterns. Of the EU/EEA countries, 19 Member States are classified as being in the West, nine in the Centre and three in the East. Liechtenstein is not included in the WHO European Region classification and, therefore, totals for West, Centre and East may not always equal the EU/EEA and non-EU/EEA totals. Data from Kosovoi are included as footnotes to Tables 1–7 and 15–21. Population data and rates Data are presented in absolute numbers and rates as cases per 100 000 population. The population estimates up to 2014 were derived from Eurostat for all EU/EEA countries and from United Nations (UN) Population Division for non-EU/EEA countries [2]. The Eurostat data are from 31 March 2015 (http://ec.europa.eu/eurostat/data/database) and the UN population data are from September 2015 (http:// esa.un.org/unpd/wpp/DVD). The population data used for HIV and AIDS for Spain and for HIV for Italy were adjusted according to the extent of sub-national coverage for relevant years. For data presented by gender and age, rates were calculated using relevant male and female population denominators from the sources described above. For i This designation is without prejudice to positions on status, and is in line with UNSCR 1244 and the ICJ Opinion on the Kosovo Declaration of Independence. Trend data For presentation of the overall trends, only countries reporting consistently were included and these are noted in the footnotes to the trend graphs. When presenting HIV trends for 2005–2014 by transmission mode, countries reporting transmission mode inconsistently or incompletely were excluded (e.g. Estonia, Poland and Turkey) from Table 8 and relevant figures reporting trends by transmission mode. Countries with varying geographic coverage of the national surveillance system over time (Spain and Italy) were also excluded from Tables 8 and 9 and from graphs showing HIV trends. When presenting trends for AIDS deaths, only countries reporting consistently were included (i.e. Bosnia and Herzegovina, Finland, Italy, Russia, Sweden, Turkmenistan, Ukraine and Uzbekistan were not included in the presentation of trends for AIDS deaths in Table 26 or the description in the text). 5 Data limitations Surveillance systems are not identical across Europe, and differences in data collection methods and testing policies could impact the results and introduce bias in comparisons between countries. Particularly, factors such as underreporting and reporting delay may influence the country figures and rankings presented in the report. The data in the report are to be considered as provisional because they are subject to regular updates (e.g. detection and deletion of duplicate cases, inclusion of new information about cases already reported). The limitations described below and country comments in Annex 5 and the information on HIV and AIDS case reporting systems available in Annexes 4 and 5 need to be taken into account when interpreting the data presented here. Official reports of newly diagnosed cases of HIV do not represent true incidence. Newly reported HIV diagnoses include recently infected individuals as well as those who were infected several years ago but only recently tested for HIV. These reports are also influenced by several factors such as the uptake of HIV testing, patterns of reporting, the long incubation period and a slow progression of the disease. In order to better interpret trends in HIV case reporting data, the total numbers of HIV tests performed annually for diagnostic purposes (excluding unlinked anonymous tests and screening of blood donations) are presented to help provide some background on HIV testing patterns. 97 HIV/AIDS surveillance in Europe 2014 Although the table in Annex 6 adjusts for reporting delay for those countries where this is possible, no adjustments are made for underreporting or underascertainment bias. Fewer than 40% of European countries have evaluated their surveillance systems for underreporting and only two have published the results [4]. Previous estimates of underreporting range from 0% to 25% for AIDS cases [3], while national estimates of underreporting for HIV can range from 10% (Iceland and Italy) to around 40% (Germany and the UK) [4, 5]. Estimates with regard to the underreporting of AIDSrelated deaths are not available. References 1 Heisterkmap SH, Jager JC, Ruitenberg EJ, van Druten JAM, Downs AM. Correcting Reported Aids Incidence: A statistical approach. Statistics in Medicine. Vol. 8, 963-976 (1989). 2 United Nations, Department of Economic and Social Affairs, Population Division. World Population Prospects: The 2015 Revision, DVD Edition. New York; 2015. Available at: http://esa.un.org/unpd/ wpp/DVD/ [accessed 14 September 2015]. 3 EuroHIV. Completeness of AIDS case reporting in Europe. HIV/AIDS Surveillance in Europe, Quarterly Report 1996. Paris: Institut de médecine et d’épidémiologie africaines; 1996. No.49:30-33. 4 EuroHIV. EuroHIV 2006 survey on HIV and AIDS surveillance in the WHO European Region. Saint-Maurice: Institut de veille sanitaire; 2007. 5 Personal communication to ECDC. F. Cazein, 08/11/12. 98 SURVEILLANCE REPORT HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Annex 2 List of variables* for 2014 HIV/AIDS data collection HIVAIDS case-based HIV case-based AIDS case-based HIV aggregated AIDS aggregated HIV tests aggregate RecordID RecordType RecordTypeVersion Subject Status DataSource ReportingCountry DateUsedForStatistics Age Gender Outcome DateOfOnset DateOfDiagnosis DateOfNotification Classification ClinicalCriteria LaboratoryResult EpiLinked RecordID RecordType RecordTypeVersion Subject Status DataSource ReportingCountry DateUsedForStatistics Age Gender Outcome DateOfOnset DateOfDiagnosis DateOfNotification Classification ClinicalCriteria LaboratoryResult EpiLinked RecordType RecordTypeVersion Subject DataSource AgeClass Gender ReportingCountry DateUsedForStatistics Classification Number of cases - RecordType RecordTypeVersion Subject DataSource AgeClass Gender ReportingCountry DateUsedForStatistics Classification Number of cases - RecordType RecordTypeVersion Subject DataSource DateUsedForStatistics ReportingCountry NumberOfTests - HIVType Stage Transmission TransmissionHetero TransmissionMTCT HIVStatus DateOfAIDSDiagnosis CountryOfBirth CountryOfNationality RegionOfOrigin CD4Cells ProbableCountryOfInfection DateOfDeath - HIVType ARTTreatment Transmission TransmissionHetero TransmissionMTCT DateOfHIVDiagnosis CountryOfBirth CountryOfNationality RegionOfOrigin AgeClass AIDSIndicatorDisease DateOfDeath DateOfReportDeath Transmission - Transmission - - Common set of variables RecordID RecordType RecordTypeVersion Subject Status DataSource ReportingCountry DateUsedForStatistics Age Gender DateOfDiagnosis DateOfNotification Disease-specific variables HIVType ART Transmission TransmissionPartner HIVStatus CountryOfBirth RegionOfOrigin First CD4Count First CD4Date ProbableCountryOfInfection AcuteInfection YearOfArrival LastAttendanceDate CD4Latest CD4LatestDate VLLatest VLLatestDate DateofAIDSDiagnosis AIDSIndicatorDiseaases DateofDeath DeathCause * Additional optional variables ‘PlaceOfNotification’ and ‘PlaceOfResidence’ were added from TESSy metadataset 20 for all diseases and can be reported via HIV case-based and HIV aggregate. 99 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Annex 3 Completeness of variables for data reported in 2013 and 2014 EU/EEA Countries Age Gender Date of diagnosis Date of notification Transmission Date of AIDS diagnosis Date of death Country of birth Region of origin CD4 cell count Probable country of infection WHO European Region Age Gender Date of diagnosis Date of notification Transmission Date of AIDS diagnosis Date of death Country of birth Region of origin CD4 cell count Probable country of infection 100 Number of countries 2013 Completeness % Minimal Maximal Number of countries 2014 Completeness % Minimal Maximal 30 30 30 27 30 30 24 22 23 22 25 99.8 99.8 100 74.7 81.6 31.3 5.9 57.2 71.5 64.2 42.8 83.3 86.7 100 74.1 9.1 3.4 0.3 34.3 32.6 7.3 5.5 100 100 100 100 98.7 100 100 100 100 97.7 100 31 31 31 29 31 31 26 22 23 23 25 99.8 99.7 100 74.3 80.3 29.3 3.4 56.9 69.1 61.9 43.2 84.8 85.6 100 1.1 9.1 3.1 0.3 38.4 63.9 4.5 2.6 100 100 100 100 100 100 100 100 100 100 100 49 49 49 41 48 46 38 36 37 35 37 99.8 99.7 100 48.9 87.4 23.6 9.3 39.9 48.8 38.9 30.1 83.3 86.7 100 48.9 9.1 3.4 0.3 34.3 32.6 7.3 5.5 100 100 100 100 100 100 100 100 100 97.7 100 49 49 49 42 48 44 40 35 36 36 36 99.8 99.6 100 49.7 86.5 17.9 3.5 41.2 48.5 37.9 31.8 84.9 85.6 100 1.1 9.1 3.1 0.3 38.5 48.5 4.5 2.6 100 100 100 100 100 100 100 100 100 100 100 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Annex 4a HIV surveillance system overview: data source information Country EU/EEA Austria Belgium Bulgaria Cyprus Croatia Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland HIV Data source Type HIV Period Legal Coverage AT-HIV BE-HIV/AIDS BG-HIV CY-HIV/AIDS HR-CNIPH CZ-HIV/AIDS DK-HIV EE-NAKIS FI-NIDR FR-HIVAIDS [email protected] EL-NOTIFIABLE_DISEASES HU-HIV/AIDS IS-SUBJECT_TO_REGISTRATION IE-CIDR HIVAIDS HIVAIDS HIVAIDS HIVAIDS HIV HIVAIDS HIVAIDS HIV HIV HIVAIDS HIV HIVAIDS HIVAIDS HIV HIVAIDS 1980-2014 1978-2014 1986-2014 1986-2014 1985-2014 1985-2013 1990-2014 1988-2014 1980-2014 2003-2014 1993-2014 1981-2014 1985-2014 1983-2014 1981-2014 V V C C C C C C C C C C C C C Co Co Co Co Co Co Co Co Co Co Co Co Co Co Co Italy Latvia IT-COA-ISS LV-HIV/AIDS HIV HIVAIDS 2004-2014 1987-2014 C C Co Co Liechtenstein CH-SFOPH-LI HIV 1985-2014 V NS/unk Lithuania Luxembourg Malta Netherlands Norway Poland Portugal Romania Slovakia Slovenia Spain Sweden United Kingdom Non-EU/EEA Albania Andorra Armenia Azerbaijan Belarus Bosnia and Herzegovina former Yugoslav Republic of Macedonia, the Georgia Israel Kazakhstan Kyrgyzstan LT-AIDS_CENTRE LU-HIVAIDS MT-DISEASE_SURVEILLANCE NL-HIV/AIDS NO-MSIS_B PL-HIV PT-HIVAIDS RO-RSS SK-EPIS SI-HIVAIDS ES-HIV SE-SmiNet UK-HIVAIDS HIV HIVAIDS HIV HIVAIDS HIVAIDS HIVAIDS HIVAIDS HIVAIDS HIVAIDS HIVAIDS HIV HIVAIDS HIVAIDS 1988-2014 1983-2014 1986-2014 1980-2014 1980-2014 1984-2014 1983-2014 1985-2014 1985-2014 1985-2014 2003-2014 1983-2014 1981-2014 C V C V C C C C C C C C V Co Co Co Co Co Co Co Co Co Co Co Co Co AL-NIoPH AD-MoHWFH AM-NAC AZ-AIDS-CENTER-NEW BY-NAC BA-FMoH-MoHSWRS MK-NHASS HIVAIDS HIVAIDS HIVAIDS HIVAIDS HIVAIDS HIV HIV 1993-2014 2004-2014 1988-2014 1987-2014 1981-2014 1986-2013 1987-2014 C V V V C C C Co Co Co Se Co Co Co GE-IDACIRC IL-MOH KZ-RCfAPC KG-HIV KG 2008 HIVAIDS HIVAIDS HIV HIVAIDS 1989-2014 1981-2014 1987-2014 1987-2014 C C NS/unk V Co Co NS/unk Co Moldova MD-NAC HIVAIDS 1987-2014 V Other Montenegro Monaco Russia San Marino Serbia* Switzerland Tajikistan Turkey Turkmenistan Ukraine Uzbekistan ME-IOPH MC-MoSH-GEN RU-MOH SM-AIDS/HIV RS-NAC CH-FOPH TJ-RHAC TR-MOH TM-NAC UA-NAC UZ-RAC HIVAIDS HIV HIVAGGR HIV HIVAIDS HIV HIVAIDS HIV HIV HIVAGGR HIV 1989-2014 1985-2014 2010 1985-2013 1984-2014 1985-2014 1991-2014 1984-2014 1981-2012 1987-2014 1981-2010 C C C C C C C C V V V Co Co Co Co Co Co Co Co Co Other Co Comments HIV record type used 1986 through 2013 HIV record type used 1990-2013 Data source EE-HIV used 1988-2012 Data source DE-HIV-Pre-IfSG used 1993-2001 Data source IE-HIV/AIDS used for for years 1981-2011 See Annex 5 about historical coverage Same data source in HIV record type used for 1987-2013; HIVAIDS record type in 2014 only Cases reported through Switzerland's surveillance system using another data source HIV record type used in years 1980-2013 HIV record type used in years 1985-2013 See Annex 5 about historical coverage Data source SE-SweHIVReg used 1983-2009 HIV record type used 1981-2013 Did not report 2014 cases Data source KG-RCfAPC-GE8 used for 19872007; HIV record type used for 1987-2013 Data source MD-NAC-NCfPC-GEN used 20082013; HIV record type used 1987-2013 Did not report 2014 cases HIV aggregate record type used 1984-2001 Did not report 2013 or 2014 cases Did not report cases 2011-2014 * Data from Kosovo (without prejudice to positions on status, and in line with UNSCR 1244 and the ICJ Opinion on the Kosovo Declaration of Independence), reported through data source XK-HIV AIDS for 2014 and through data source RS-Kosova NIPH for 2000-2013. HIV record type used for all reporting years Type: HIVAIDS (HIV and AIDS joined case-based record type); HIV (HIV case-based record type); AIDS (AIDS case-based record type); HIVAGGR (HIV aggregate record type); AIDSAGGR (AIDS aggregate record type) Legal: voluntary reporting (V), compulsory reporting (C ), not specified/unknown (NS/unk) Coverage: sentinel system (Se), comprehensive (Co), not specified/unknown (NS/unk) 101 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Annex 4b AIDS surveillance system overview: data source information Country EU/EEA Austria Belgium Bulgaria Cyprus Croatia Czech Republic Denmark Type Period Legal Coverage AT-AIDS BE-HIV/AIDS BG-AIDS CY-HIV/AIDS HR-CNIPH CZ-HIV/AIDS DK-HIV HIVAIDS HIVAIDS HIVAIDS HIVAIDS AIDS HIVAIDS HIVAIDS 1980-2014 1978-2014 1986-2014 1986-2014 1985-2014 1985-2013 1980-2014 V V C C C C C Co Co Co Co Co Co Co Estonia EE-NAKIS AIDS 1988-2014 C Co Finland France FI-NIDR FR-HIVAIDS; FR-AIDS AIDS HIVAIDS 1980-2014 2003-2014 C C Co Co Germany Greece Hungary Iceland Ireland DE-AIDS EL-NOTIFIABLE_DISEASES HU-HIV/AIDS IS-SUBJECT_TO_REGISTRATION IE-CIDR AIDS HIVAIDS HIVAIDS AIDS HIVAIDS 1970-2014 1981-2014 1985-2014 1983-2014 1981-2014 V C C C V Co Co Co Co Co Italy Latvia IT-COA-ISS LV-AIDS AIDS HIVAIDS 1982-2014 1990-2014 C C Co Co Liechtenstein CH-SFOPH-LI AIDS 1985-2014 V NS/unk Lithuania Luxembourg Malta Netherlands Norway LT-AIDS_CENTRE LU-HIVAIDS MT-DISEASE_SURVEILLANCE NL-HIV/AIDS NO-MSIS_B AIDS HIVAIDS AIDS HIVAIDS HIVAIDS 1988-2014 1983-2014 1986-2014 1980-2014 1980-2014 C V C V C Co Co Co Co Co Poland Portugal Romania Slovakia Slovenia Spain Sweden United Kingdom Non-EU/EEA Albania Andorra Armenia Azerbaijan Belarus Bosnia and Herzegovina former Yugoslav Republic of Macedonia, the Georgia Israel Kazakhstan Kyrgyzstan PL-HIV PT-HIVAIDS RO-RSS SK-EPIS SI-HIVAIDS ES-AIDS HIVAIDS HIVAIDS HIVAIDS HIVAIDS HIVAIDS AIDS UK-HIVAIDS HIVAIDS 1984-2014 1983-2014 1985-2014 1985-2014 1985-2014 1980-2014 1983-2009 1981-2014 C C C C C C V V Co Co Co Co Co Co Co Co AL-NIoPH AD-MoHWFH AM-NAC AZ-AIDS-CENTER-NEW BY-NAC BA-FMoH-MoHSWRS MK-NHASS GE-IDACIRC IL-MOH KZ-RCfAPC KG-HIV KG 2008 HIVAIDS HIVAIDS HIVAIDS HIVAIDS HIVAIDS AIDS AIDS HIVAIDS HIVAIDS HIVAIDS HIVAIDS 1993-2014 2004-2014 1988-2014 1987-2014 1991-2014 1986-2013 1987-2014 1989-2014 1981-2014 1987-2014 1987-2007 C V V V C C C C C NS V Co Co Se Co Co Co Co Co Co NS Co Moldova MD-NAC HIVAIDS 1989-2014 V Co Montenegro Monaco Russia San Marino Serbia* Switzerland Tajikistan Turkey Turkmenistan Ukraine Uzbekistan ME-IOPH MC-MoSH-GEN SM-AIDS/HIV RS-NAC CH-FOPH TJ-RHAC TR-MOH TM-NAC UA-NAC UZ-RAC HIVAIDS HIV 1989-2014 1985-2014 2010 AIDS 1985-2013 HIVAIDS 1985-2014 AIDS 1985-2014 HIVAIDS 1991-2014 AIDS 1984-2014 AIDS 1981-2012 AIDSAGGR 1987-2014 AIDS 1981-2010 C C C C C C C V V V Co Co Co Co Co Co Co Co Co Co * AIDS Data source Comments AIDS record type used 1986 through 2013 HIVAIDS from data source DK-MIS used 1980-2013 AIDS record type from data source EE-AIDS used 1988-2012 Additional data from data source FR-AIDS used for the years 1978-2014 Data source IE-HIV/AIDS used for years 1981-2011 Same data source in HIV record type used for 1990-2013; HIVAIDS record type in 2014 only Cases reported through Switzerland's surveillance system using another data source Data source NO-MSIS-A and record type AIDS used in years 1980-2013 AIDS record type used in years 1985-2013 See Annex 5 about coverage AIDS surveillance discontinued in 2000 AIDS record type used 1991-2013 Did not report 2014 cases HIVAIDS record type used for AIDS only Data source KG-RCfAPC-GEN used for 19872007; AIDS record type used for 1987-2013 Data source MD-NAC-NCfPC-GEN used 20082013; AIDS record type used 1987-2013 Has not reported AIDS cases Did not report 2014 cases AIDS record type used 1985-2001 Did not report 2013 or 2014 cases Did not report cases 2011-2014 Data from Kosovo (without prejudice to positions on status, and in line with UNSCR 1244 and the ICJ Opinion on the Kosovo Declaration of Independence), reported through data source XK-HIV AIDS for 2013 and through data source RS-Kosova NIPH for 2000-2013. AIDS record type used for all reporting years Type: HIVAIDS (HIV and AIDS joined case-based record type); HIV (HIV case-based record type); AIDS (AIDS case-based record type); HIVAGGR (HIV aggregate record type); AIDSAGGR (AIDS aggregate record type) Legal: voluntary reporting (V), compulsory reporting (C ), not specified/unknown (NS/unk) Coverage: sentinel system (Se), comprehensive (Co), not specified/unknown (NS/unk) 102 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Annex 5 Country-specific comments regarding national HIV and AIDS reporting Country Comments EU/EEA Bulgaria Case-based reporting of HIV is available from 2007 onwards. Croatia The data presented in Table 4 for 2014 is 80 persons for the MSM transmission route (out of total 92 HIV diagnoses for Croatia for 2014). The reason for the discrepancy between data submitted to TESSy and national data will be investigated and duly corrected in the next reporting round. Czech Republic Foreigners with short-time stays in the Czech Republic are not included in reported data. Estonia Surveillance system was substantially modified in 2008. Previously, the probable mode of HIV transmission was not reported by Estonia (from 2003 to 2007 Estonia supplied partial information on PWID only). France Case-based data reported through TESSy are not exhaustive, because of reporting delays (cases reported several months or several years after the diagnosis) but also because of underreporting (cases that are diagnosed but never reported). The most recent estimates of underreporting are 41% in 2007-2009 for AIDS and 29% in 2013 for HIV in France. To assess the real the number of HIV and AIDS diagnoses in France it is essential to use adjusted data, which take into account both reporting delays (for the last two years) and underreporting (for the whole surveillance period). Adjusting for these factors, the estimated number of new HIV diagnoses in 2013 was 6220 95%CI [5759-6682] and estimated number of new AIDS diagnoses was 1212 95% CI [1092-1333]. The 2014 adjusted numbers of HIV and AIDS diagnoses will be available at the end of November 2015. Ireland HIV was made a notifiable disease in September 2011. HIV reporting system was modified substantially in 2012. AIDS cases and deaths among AIDS cases are now only reported if at the time of HIV diagnosis. Italy New HIV diagnoses were reported by 10 of the 22 Italian regions between 2004 and 2006, 11 regions in 2007, 12 regions in 2008, 18 regions in 2009, and all of the 22 regions of Italy for 2012 and 2013. Between 2004 and 2011, population denominators are based on the annual resident population in the regions reporting cases. From 2012 the coverage of the surveillance system is national and, thus, the total Italian population is used as a denominator. AIDS deaths for years 2011, 2012, 2013 are not reported due to lack of updated data from the national mortality register. Liechtenstein Liechtenstein with only 35 000 inhabitants has small numbers of communicable diseases. Therefore public health authorities refrain from collecting data due to limited public health added value. In 1970 Liechtenstein adopted the Swiss Law of Epidemiology. Since then all communicable disease data are reported to the officials in Switzerland as demanded by the Federal Office of Public Health. These data are reported through Switzerland to TESSy but may not represent all cases diagnosed in Liechtenstein. Luxembourg HIV tests reported up to 2010 include only tests performed at two major public laboratories and, thus, underestimate the total number of HIV tests performed during those years. From 2011, tests reported include all laboratories in the country. Malta New HIV reporting system started in 2004. Portugal PT-HIV database is now fully case-based containing details of cases diagnosed from 1983. In 2013 and 2014, the Portuguese HIV/AIDS Programme implemented a strategy to address underreporting and reporting delay, resulting in significant increases of the number of reported cases diagnosed between 1983 and 2012 which are reflected in the present report. Romania New HIV diagnoses who have AIDS are reported only in in the AIDS database and AIDS tables. The total number of new HIV diagnoses for Romania is a sum of the HIV and AIDS case reports for any given year. Data on AIDS deaths for 2013 are not complete and will be updated in future reporting years. Spain HIV reporting has existed since the 1980s in some of the 19 Autonomous Regions of Spain. For 2003-11 data are available only for 9 Regions: Asturias, Balearic Islands, Basque Country, Canary Islands, Catalonia, Ceuta, Extremadura, La Rioja, and Navarre; since 2004, data are available for 10 Regions (+ Galicia); since 2007, data are available for 11 Regions (+Madrid); since 2008, data are available for 14 Regions (+ Aragón, Castilla-La Mancha and Melilla); since 2009, data are available for 17 Regions (+ Cantabria, Castilla-León and Murcia); since 2012 data are available for 18 Regions (+Valencia). Since 2013 data are available for all the 19 Regions of Spain (+ Andalucía). Rates based on the corresponding populations for each year. AIDS reporting, 2014: for technical reasons, it has not been possible to include data from one region in 2013 and from two regions in 2014. Rates in 2013 and 2014 are based on the corresponding population. Sweden Due to changes in the HIV/AIDS surveillance system, AIDS reporting has not been mandatory since 2000. Since 2008, no AIDS data are reported from Sweden because the national AIDS surveillance system has been discontinued. Non-EU/EEA Andorra New HIV reporting system started in 2004. Belarus AIDS deaths for 2014 only include deaths among people diagnosed with AIDS in 2014 and are likely to be an under-estimate former Yugoslavic Republic of Macedonia Reported HIV cases exclude persons diagnosed with AIDS at the time of HIV diagnosis. Serbia Updated information from national statistics for two AIDS diagnoses was reported as date of diagnoses in 2008 instead of 2009. Data on HIV tests refer to the number of people tested and do not include people tested in reference laboratory or private laboratories. Turkey Reported HIV cases exclude persons diagnosed with AIDS at the time of HIV diagnosis. Reported AIDS cases only include people diagnosed with AIDS at the time of HIV diagnosis. Ukraine Ukraine data reported exclude Crimea and Sevastopol City for 2014; corresponding population denominators were used to compute rates; Table 7: MTCT cases for 2005-2007 are calculated from best available data, data for 2008-2012 data are validated and final, and data for 2013 and 2014 are provisional and may be adjusted in the coming few years. 103 HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Annex 6 HIV diagnoses and rate per 100 000 population, adjusted for reporting delay and adjustment coefficients*, EU/EEA countries, 2011–2014 Country** EU/EEA Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France*** Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein Lithuania Luxembourg Malta Netherlands Norway Poland Portugal Romania Slovakia Slovenia Spain Sweden United Kingdom Total EU/EEA Non-EU/EEA Albania Andorra Armenia Azerbaijan Belarus Bosnia and Herzegovina former Yugoslav Republic of Macedonia Georgia Israel Kazakhstan Kyrgyzstan Moldova Monaco Montenegro Russia San Marino Serbia Switzerland Tajikistan Turkey Turkmenistan Ukraine Uzbekistan Total Non-EU/EEA WHO European Region Total West Total Centre Total East Total WHO Region 2011 N Rate 2012 N Rate 2013 N Rate 2014 N Rate 2011 Adjustment coefficients* 2012 2013 2014 328 1183 201 77 54 153 266 366 172 6085 2699 953 162 23 328 3928 299 1 166 59 21 1174 269 1131 1904 784 49 55 3493 399 6305 33087 3.9 10.8 2.7 1.8 6.4 1.5 4.8 27.5 3.2 9.4 3.3 8.6 1.6 7.2 7.2 6.6 14.4 2.8 5.4 11.6 5.1 7.0 5.5 3.0 18.0 3.9 0.9 2.7 10.6 4.2 10.0 6.7 326 1229 157 74 58 212 201 315 156 6217 2978 1142 219 19 349 4333 339 0 160 63 30 1104 242 1131 1880 870 50 45 3732 396 6497 34525 3.9 11.1 2.1 1.7 6.7 2.0 3.6 23.8 2.9 9.5 3.6 10.3 2.2 5.9 7.6 7.3 16.6 0.0 5.3 12.0 7.2 6.6 4.9 3.0 17.8 4.3 0.9 2.2 9.9 4.2 10.2 6.9 266 1125 200 85 54 235 233 325 159 6220 3288 890 240 12 343 3983 340 0 177 68 36 1085 233 1158 1801 898 83 44 3866 375 6385 34207 3.1 10.1 2.7 2.0 6.2 2.2 4.2 24.6 2.9 9.5 4.0 8.1 2.4 3.6 7.5 6.7 16.8 0.0 6.0 12.7 8.5 6.5 4.6 3.0 17.2 4.5 1.5 2.1 8.3 3.9 10.0 6.7 235 1039 247 92 62 232 282 291 190 3525 785 271 13 363 3861 347 1 141 81 40 1006 308 1273 1234 791 86 54 3366 385 6509 32605 2.8 9.3 3.4 2.2 7.2 2.2 5.0 22.1 3.5 4.4 7.2 2.7 3.9 7.9 6.4 17.3 2.7 4.8 14.8 9.4 6.0 6.0 3.3 11.8 4.0 1.6 2.6 7.2 4.0 10.1 6.4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.01 0 0 0 0.06 0 0.02 0 0.01 0.13 0 0 0 0 0.02 0.02 0.03 0 0 0 0 0 0 0 0 0 0.01 0 0 0 0 0 0.01 0 0 0 0.09 0 0.04 0 0.03 0.17 0 0 0 0 0.04 0.04 0.04 0 0 0 0 0 0 0 0 0.01 0.02 0 0.03 0 0.05 0 0.02 0 0 0 0.12 0 0.07 0 0.05 0.23 0 0 0 0 0.06 0.06 0.05 0 0 0 0 0.1 0 0.1 0 0.05 0.27 0 0.1 0 0.16 0.01 0.2 0 0 0 0.18 0 0.21 0.15 0.2 0.45 0 0 0.1 0 0.1 0.43 0.09 78 2 182 548 1196 27 1 2.7 2.6 6.1 5.9 12.6 0.7 0.0 81 2 228 517 1223 25 15 2.8 2.6 7.7 5.5 12.9 0.7 0.7 119 5 238 514 1533 27 15 4.1 6.6 8.0 5.4 16.1 0.7 0.7 77 3 332 604 1811 2.7 3.9 11.0 6.3 19.1 30 1.4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 429 450 1999 614 721 0 9 8 127 559 978 654 0 17305 25887 31046 3562 24805 59413 59413 10.2 5.9 12.1 11.1 17.7 0.0 1.4 25.1 1.4 7.1 12.6 0.9 38.1 12.2 7.6 1.9 22.2 8.4 8.4 534 487 2011 701 757 0 14 5 130 621 849 1069 0 16850 26119 32549 4150 24484 61183 61183 12.9 6.3 12.0 12.4 18.6 0.0 2.2 15.0 1.4 7.7 10.7 1.4 37.2 12.2 7.9 2.2 21.8 8.5 8.5 480 473 2140 503 706 0 10 1 149 576 893 1319 17860 27561 31991 4637 25709 62337 62337 11.8 6.1 12.5 8.8 17.3 0.0 1.6 3.0 1.7 7.1 11.0 1.7 39.5 12.7 7.6 2.4 22.8 8.6 8.6 541 477 2350 651 831 0 20 3 136 541 985 1848 15796 27037 29728 5219 24683 59630 59647 13.4 6.0 13.5 11.1 20.4 0.0 3.2 8.9 1.5 6.6 11.9 2.4 36.9 12.7 7.0 2.7 22.3 8.2 8.2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.00 0.05 0.00 0.00 0.03 0.03 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.00 0.06 0.01 0.00 0.03 0.03 0 0 0 0 0 0 0 0 0 0.01 0 0 0 0 0 0 0.00 0.08 0.01 0.00 0.04 0.04 0.01 0 0 0.01 0 0 0 0 0 0.08 0.05 0 0.02 0 0 0 0.00 0.09 0.05 0.00 0.05 0.05 * The coefficients present the adjustments for the current year of reporting. ** Country-specific comments are in Annex 5. For Italy and Portugal, specific additional adjustments were applied to align with national methods. *** French data for 2011-2013 are adjusted for both reporting delay and underreporting. These adjustments for 2014 were not available in time for full inclusion in this report, but it is estimated that 6584 people were diagnosed with HIV in France during 2014. EU/EEA, West and Regional totals’ adjustments are calculated 104 including only reporting delay adjustments for France and, thus, may sum to more than the country total for 2014. HIV/AIDS surveillance in Europe 2014 SURVEILLANCE REPORT Annex 7 HIV/AIDS surveillance in Europe: participating countries and national institutions Country EU/EEA Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland Ireland Italy Latvia Liechtenstein Lithuania Luxembourg Malta Netherlands Norway Poland Portugal Romania Slovakia Slovenia Spain Sweden United Kingdom Non-EU/EEA Albania Andorra Armenia Azerbaijan Belarus Bosnia and Herzegovina former Yugoslavic Republic of Macedonia Georgia Israel Kazakhstan Kyrgyzstan Moldova Monaco Montenegro Russia San Marino Serbia Switzerland Tajikistan Turkey Turkmenistan Ukraine Uzbekistan National institutions Federal Ministry of Health, Family and Youth Scientific Institute of Public Health Ministry of Health Croatian National Institute of Public Health Ministry of Health National Institute of Public Health Statens Serum Institut Health Board National Public Health Institute (KTL) Institut de veille sanitaire Robert Koch Institute Hellenic Center for Disease Control and Prevention National Center for Epidemiology (Országos Epidemiológiai Központ) Health Protection Agency Centre for Infections Health Protection Surveillance Centre (HPSC) Ministry of Health DG Prevention - Unit V Centre for Disease Prevention and Control of Latvia Principality of Liechtenstein Center for Communicable Diseases and AIDS National Service of Infectious Diseases, Centre Hospitalier Department of Health Promotion and Disease Prevention National Institute for Public Health and the Environment (RIVM) Norwegian Institute of Public Health – Department of Infectious Disease Epidemiology National Institute of Public Health – National Institute of Hygiene (NIZP-PZH) National Institute of Health Dr Ricardo Jorge (Instituto Nacional de Saúde Doutor Ricardo Jorge, I.P.) Institute of Public Health and National Institute for Infectious Diseases "Prof. Dr. Matei Bals" Regional Public Health Authority of capital Bratislava National Institute of Public Health Instituto de Salud Carlos III Centro Nacional de Epidemiologia Swedish Institute for Infectious Disease Control Public Health England National Institute of Public Health Ministry of Health, Social Welfare and Family National Center for AIDS Prevention Azerbaijan AIDS Center National Centre for Hygiene, Epidemiology and Public Health Federal Ministry of Health, Republika Srpska;Serbia Institute for Public Health of Serbia Public Health Institute Infectious Diseases, AIDS & Clinical Immunology Research Center Ministry of Health National Center for the Prevention and Control of AIDS Republic Centre for AIDS Prevention and Control National AIDS Center; National Center for Preventative Care Ministry of Social Health Institute of Public Health of Montenegro Federal Scientific and Methodological Center for Prevention and Control of AIDS Ospedale di Stato Institute of Public Health of Serbia Bundesamt für Gesundheit Republican HIV/AIDS Center Public Health Institute of Turkey, Ministry of Health National AIDS Prevention Center State Institution "Ukrainian Center for Socially Dangerous Disease Control of the MOH of Ukraine" Republican AIDS Center 105 HOW TO OBTAIN EU PUBLICATIONS Free publications: • one copy: via EU Bookshop (http://bookshop.europa.eu); • more than one copy or posters/maps: from the European Union’s representations (http://ec.europa.eu/represent_en.htm); from the delegations in non-EU countries (http://eeas.europa.eu/delegations/index_en.htm); by contacting the Europe Direct service (http://europa.eu/europedirect/index_en.htm) or calling 00 800 6 7 8 9 10 11 (freephone number from anywhere in the EU) (*). 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