МЕХАНИЗМЫ ДЕЙСТВИЯ ИОНИЗИРУЮЩИХ ИЗЛУЧЕНИЙ ПРИ

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15
:
1.
.,
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.,
. //
11.
.,
.,
.
. 1978. . 6-21.
.,
2.
. //
. 1989. . 60. .
.
1983. . 121-123.
12.
.,
60-80.
».
3.
.,
.,
6. .
. //
. 2005.
40-46.
.,
., A
.
.
6.
2. . 268-276.
7.
. 1984. .
.
. //
. 2002.
.: «
» 3 . . 1. . 174-
. //
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.
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.
.
. 1987. . 87-106.
8.
. //
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.
. 1974. . 31-34.
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.
.
.
.- .
.
.
.
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.
., 1992. 88 .
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.,
.,
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.,
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.
.,
. // XV
«
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187-193.
5.
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13.
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. 674-
675.
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// Space Res. 2001. Vol. 39. 4, P. 1-12.
5, 2008
16
MECHANISMS OF ACTION OF IONIZING RADIATIONS ON RIZING
OF LOCAL CHANGES OF BIOLOGICAL CELULARE STRUCTURES
IN CONDITIONS OF SPACE FLIGHT
Dmitrievsky I.M.1, Yurov S.S.2, Cozhocaru A.F.2, Nechitailo G.S.3
1
The Moscow State Physics-Engineering Institute, 2Institute of Cell Biophysics RAS, Pushchino
of Moscow region, 3Institute of Biochemical Physics RAS, Moscow
Influence of ionizing factors of cosmic flight in experiments on bacteriophage 4Br+, on
seeds of tomato Lycopersicon esculentum Mill, laboratory mice and biological eye structures
was studied. Rare effects of macrolocal action of hadronic radiation of high energy and heavy
charged particles on phage-particles were manifested as essential damages on the level of cellular structures and whole cells, also as specific macrodamages of DNA (long and multiple deletions) and membranes, at the expense of multiple generation of second particles and of its narrow angle distribution. Gamma-radiation did not exert macrolocal changes in 4Br+ cells and
had another microlocal mutagenic action. A row of natural nontoxic membrane-tropic compounds with antioxidant and energy-stimulating properties is proposed for protection from radiation. On base of calculation and experimental data flares in eyes and considerable improving of cosmonaut sight keenness we explain by local action of polarized Cherenkov radiation,
occurred under the passage of ionizing particles through the eye, and of polarized light reflected
from earth atmosphere. Flares are also explained by mechanism of direct excitement of eye rodopsyne being high sensitive to the light and ionizing particles.
5, 2008