16 616.12-008.331.1.334-055.1-053.81-07(045) . , . (127473 *, , (410028 . . *, . * , .20/1) svlvs@mail.ru , , 141) liana@san.ru I , - . . - c . : , , - , ( 1,3 . - ) , - , . 25-64 [3,5]. 36% , ( 3–4 [2,5]. ( ) [1]. – - 7 , I , [5]. , - 44 , 20 31,9+1,14), ( . 2,12+0,22), - . ) - , I 45 , , , I ( . <5 - . - [1,6]. « , » 2004. - . 12 10 2009 ( 17 110/70 129/85 . 14,8 .), . ., –11,3 ., . : [4]. - 13,3 , - ( ( ), ) ( (AND, ) 2421/2021, [4]. ) - : I (n=20), II – (n=24), . I - II ( : – 15,5 ., - . 1). – 1 I . ( ) ( ( ( ( ( ( ( (n=12) 28,16+2,62 --25,41+1,26 123,16+1,95 108,23+2,87 119,06+1,69 76,38+1,58 63,48+2,81 73,51+1,39 . . . . . . ) .) .) .) .) .) .) II (n=24) 31,27+1,79 2,16+0,27 27,85+1,59 143,77+2,35 123,88+2,57 138,77+2,63 85,39+1,97 70,31+2,02 80,04+1,91 (n=20) 32,66+1,73 1,95+0,38 26,56+0,88 142,32+2,21 122,07+3,21 137,62+2,02 89,40+1,84 71,5+2,30 84,97+1,37 ( – AI) [2]. TOSHIBA ( 7,5 – , ) (TAMX), - : (Vps), (Ved), - STATISTICA-6 Excel. Microsoft . M- +SE, , SE - =0,05. (TAV). . , 54,5% , , , , . . 1,0-1,5 , , 2 - , - - . , - , 28% , 10 2009 - 18 ( . 2). - , , , , . - , . - ( ), 17,7% ( . 2). ( [8]. ): , - [7, 9] ( : I - ) 12,2% II , 28,0% ( . 2). 2 I ( ( ( ( . . . . . .) . .) ( ( (n=12) 11,5+0,36 9,73+0,54 9,63+0,57 8,43+0,5 47,0+1,26 45,16+1,49 ; **-p<0,01 .) .) .) .) *-p<0,05 II (n=24) 20,52+1,09 *** 12,45+1,19 ** 13,58+0,73 *** 9,55+0,93 * 60,18+2,39** 53,45+2,03** ; ***-p<0,001 (n=20) 12,7+0,36 9,97+0,59 9,70+0,40 8,66+0,42 52,77+1,14** 50,66+1,50* ; -p<0,05 I ; -p<0,01 I 18,9%, TAV 18,3% . 3). , , , - , , . , Vps 15,8%, Ved 12,4%, TAMX TAV 10,2%, Ved: 76,0% II 78,5%, I ( . 3). 9,3% c , . Ved , , - , . I, ) . ( I) - . 3). , - , : 23,2%, - : 20,0%, Ved - , ( Vps , 21,7%, (II ) 33,3% ( 22,4%, . 4). AI AMX , 10 2009 19 , . 4). 7,0%, (I ): 18,3%, 16,0% ( ) , - : 24,1%, 7,9% ( - 22,3%, . 4). ( . 4). 3 I Vps ( Ved ( TAMX ( TAV ( .) .) Vps ( Ved ( TAMX ( TAV ( .) .) Vps ( Ved ( TAMX ( TAV ( .) .) .) .) .) .) .) ) (n=12) (n=20) II (n=24) 81,73+9,48 21,16+2,90 29,75+3,76 16,76+2,20 72,16+3,39 20,61+1,88 28,93+1,90 15,89+1,07 83,58+5,38 23,17+2,05 31,64+1,90 17,52+1,05 67,06+8,28 10,73+1,88 19,2+3,29 10,3+1,75 62,95+3,67 5,64+0,63 17,16+1,23 9,2+0,76 71,04+3,52 9,93+1,58 18,49+1,49 9,35+0,79 41,56+8,07 5,75+0,96 11,03+2,02 5,33+0,99 46,65+2,60 4,95+0,78 12,51+1,07 6,08+0,53 52,79+4,32 8,84+1,71 13,66+1,33 6,51+0,78 4 I (n=20) II (n=24) ( .) .) 0,077+0,004 8,27+0,64 0,063+0,002** 9,46+0,58* 0,060+0,002** 11,20+0,77* ( .) .) 0,082+0,004 7,22+0,95 0,060+0,002** 8,73+0,44 0,068+0,002** 9,34+0,63* ( .) .) 0,068+0,006 5,21+0,73 ; **-p<0,01 ; 0,063+0,001* 6,56+0,35* 0,062+0,002* 7,61+0,50* ; I( I( I( *-p<0,05 -p<0,05 (n=12) I - , - , - . . - , . . 10 2009 20 , - , ( I – ) – , , (<5 1. . – 2006. – 2. 3. 4. . 9. – . 5-12. ., . . – ., 1999. – .83-88. ., . – 2007. – 1. – .4-7. ., ., . ( I). , . - .– . // ., 2005. – : , - . // - ) . . 64 . 5. . . ( . ., - .) . – ., 2005. – 5-16. – 734 . 6. Mancia G., Parati G. // J. Hypertens– 2003.–Vol.21–P.17-23. 7. Safar M.E., Levy B. I., StruijkerBoudier H. // Circulation–2003.–Vol.107–P.2864. 8. Sega R., Corrao G.,Bombelli M. et al. // Hypertension–2002.–Vol.39–P.710. 9. Vasan R.S. // Eng.J. Med. –2001.– Vol.345–P.1291-1297. VARIABILITY OF BLOOD PRESSURE AND VASCULAR BLOOD FLOW IN YOUNG WITH ARTERIAL HYPERTENSION S.V. Lyamina, N.P.Lyamina*, V.N. Senchikhin*, .A. Dodina* Federal Educational Institution of High Professional Education Moscow State Medical Stomatological University (20/1, Delegatskaya str.,Moscow, 127473) svlvs@mail.ru *Federal State Institution Saratov Research Institute of Cardiology Rosmedtechnologii (141, Chernyshevskogo str., Saratov, 410028) liana@san.ru Even in young patients with arterial hypertension the abnormality of the vascular wall’s tone in great and peripheral vessels can be discovered. Indeed in young patients with the initial stage of the disease the elastance of the vessels is decreased. Excessive variability of blood pressure (BP) worsen the elastance in young patients with arterial hypertension. Keywords: arterial hypertension, young age, elastance of the vessels, variability of BP. 10 2009